NO166643C - Fremg.maate for fremst. av den hoeyredreiende, optiske isomer av diastereomer a av ym-09730, med kjem. navn (+)-2,6-dimethyl-4-(n-nitrofenyl)-1,4-dihydropyridin-3,5-dicarboxylsyre-3-(1-benzylpyrrolidin-3-yl)-ester-5-methylester. - Google Patents

Fremg.maate for fremst. av den hoeyredreiende, optiske isomer av diastereomer a av ym-09730, med kjem. navn (+)-2,6-dimethyl-4-(n-nitrofenyl)-1,4-dihydropyridin-3,5-dicarboxylsyre-3-(1-benzylpyrrolidin-3-yl)-ester-5-methylester.

Info

Publication number
NO166643C
NO166643C NO854062A NO854062A NO166643C NO 166643 C NO166643 C NO 166643C NO 854062 A NO854062 A NO 854062A NO 854062 A NO854062 A NO 854062A NO 166643 C NO166643 C NO 166643C
Authority
NO
Norway
Prior art keywords
ester
isoms
benzylpyrrolidin
dihydropyridine
diastereomer
Prior art date
Application number
NO854062A
Other languages
English (en)
Norwegian (no)
Other versions
NO854062L (no
NO166643B (no
Inventor
Kazuharu Tamazawa
Hideki Arima
Minoru Okada
Yasuo Isomura
Klaus K Schmiegel
James H Wikel
Original Assignee
Yamanouchi Pharma Co Ltd
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd, Lilly Co Eli filed Critical Yamanouchi Pharma Co Ltd
Publication of NO854062L publication Critical patent/NO854062L/no
Publication of NO166643B publication Critical patent/NO166643B/no
Publication of NO166643C publication Critical patent/NO166643C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO854062A 1985-01-24 1985-10-14 Fremg.maate for fremst. av den hoeyredreiende, optiske isomer av diastereomer a av ym-09730, med kjem. navn (+)-2,6-dimethyl-4-(n-nitrofenyl)-1,4-dihydropyridin-3,5-dicarboxylsyre-3-(1-benzylpyrrolidin-3-yl)-ester-5-methylester. NO166643C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1205185 1985-01-24

Publications (3)

Publication Number Publication Date
NO854062L NO854062L (no) 1986-07-25
NO166643B NO166643B (no) 1991-05-13
NO166643C true NO166643C (no) 1991-08-21

Family

ID=11794796

Family Applications (1)

Application Number Title Priority Date Filing Date
NO854062A NO166643C (no) 1985-01-24 1985-10-14 Fremg.maate for fremst. av den hoeyredreiende, optiske isomer av diastereomer a av ym-09730, med kjem. navn (+)-2,6-dimethyl-4-(n-nitrofenyl)-1,4-dihydropyridin-3,5-dicarboxylsyre-3-(1-benzylpyrrolidin-3-yl)-ester-5-methylester.

Country Status (12)

Country Link
JP (1) JPS61267577A (instruction)
KR (1) KR900002342B1 (instruction)
CN (1) CN1023483C (instruction)
AT (1) AT390613B (instruction)
CA (1) CA1273931A (instruction)
DK (1) DK468385A (instruction)
ES (1) ES8607284A1 (instruction)
FI (1) FI83517C (instruction)
GR (1) GR852497B (instruction)
IT (1) IT1221762B (instruction)
MX (1) MX260A (instruction)
NO (1) NO166643C (instruction)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60134557D1 (de) 2000-08-01 2008-08-07 Kaneka Corp Neue carbonylreduktase, deren gen und verfahren zu dessen verwendung
KR100939347B1 (ko) 2005-07-20 2010-01-29 (주)카이로드 광학적으로 순수한 (ｓ)-3-히드록시 피롤리딘의 제조방법
CN101643469B (zh) * 2008-12-27 2012-11-21 武汉百科药物开发有限公司 一种盐酸巴尼地平的合成工艺
EP4382529A1 (en) 2022-12-07 2024-06-12 Bayer Consumer Care AG A process for preparing pure (3s)-pyrrolidin-3-ol and pure (3s)-pyrrolidin-3-ol hydrochloride

Also Published As

Publication number Publication date
KR860005637A (ko) 1986-08-11
FI83517C (fi) 1991-07-25
DK468385A (da) 1986-07-25
NO854062L (no) 1986-07-25
DK468385D0 (da) 1985-10-14
GR852497B (instruction) 1986-02-18
ES8607284A1 (es) 1986-05-16
FI853697L (fi) 1986-07-25
FI83517B (fi) 1991-04-15
ATA297085A (de) 1989-11-15
MX260A (es) 1995-01-31
IT8522489A0 (it) 1985-10-15
CA1273931A (en) 1990-09-11
CN1023483C (zh) 1994-01-12
NO166643B (no) 1991-05-13
CN85107590A (zh) 1986-07-23
KR900002342B1 (ko) 1990-04-12
AT390613B (de) 1990-06-11
IT1221762B (it) 1990-07-12
JPS61267577A (ja) 1986-11-27
FI853697A0 (fi) 1985-09-26
ES547696A0 (es) 1986-05-16

Similar Documents

Publication Publication Date Title
PT84611B (pt) Processo para a preparacao de benzenossulfonato de 2-(2-aminoetoximetil)-4-(2-clorofenil)-1,4-di-hidro-6-metilpiridino-3,5-dicarboxilato 3-etilico 5-metilico
GB2164336B (en) 4-aryl-1,4-dihydropyridine-3,5-dicarboxylate derivatives
KR910018025A (ko) 약제로서 n-알킬화 1,4-디히드로피리딘디카르복실산 에스테르의 용도, 신규 화합물-및 그의 제조방법
NO166643C (no) Fremg.maate for fremst. av den hoeyredreiende, optiske isomer av diastereomer a av ym-09730, med kjem. navn (+)-2,6-dimethyl-4-(n-nitrofenyl)-1,4-dihydropyridin-3,5-dicarboxylsyre-3-(1-benzylpyrrolidin-3-yl)-ester-5-methylester.
FI862111A7 (fi) Foerfarande foer framstaellning av 2(n-bensyl-n-metylamino)-etylmetyl-2,6-dimetyl-4-(m-nitrofenyl) -1,4-dihydropyridin-3,5-dikarboxylat och dess hydrokloridsalt.
NL7711827A (nl) 1.4-dihydro-2.6-dimethyl-4-(3-nitrofenyl)- 3.5-pyridinedicarbonzuur-isopropyl-(2-pro- poxy-ethyl)ester, werkwijzen ter bereiding ervan, alsmede de toepassing als perifere vasodilatator.
EP0247345A3 (en) 1,4-dihydropyridine-3,5-dicarboxylates incorporating an alkyleneaminoalkylene-heteroatom moiety
DK165686A (da) 1,4-dihydropyridin-3,5-dicarboxylatderivater
ES551768A0 (es) Un procedimiento para la preparacion del isomero optico dextrogiro del diastereomero a del 2,6-dimetil-4-(m-nitrofenil)-1,4-dihidropiridin-3,5-dicarboxilato de 3-(1-bencilpirrolidin-3-ilo) y 5-metilo
PT84566B (pt) Processo para a preparacao do novo composto com actividade optica (+)-1,4- -dihidro-2,6-dimetil-4-(3-nitrofenil)-piridina-3,5-dicarboxilato de 3-metil-5- -{3-(4,4-difenil-piperidil-1)-profilo} e de composicoes farmaceuticas que o contem
FI894455A7 (fi) 1,4-dihydropyridiinijohdannaisia
EP0260605A3 (en) Dihydropyridine-5-phosphonic acid cyclic ester
IT8320800A0 (it) 2,6-dimetil-3,5-bis-(1-adamantilossicarbonil)-4-(2-difluorometossifenil)-1,4-diidropiridina.
FI853574L (fi) Dihydropyridin -3,5-dikarboxylsyraesterderivat.
DK162442C (da) 3-(2-(furoyl)-5-(eventuelt substitueret)alkoxy-carbonyl-2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridiner og farmaceutisk praeparat indeholdende saadanne forbindelser
NO922795L (no) Anvendelse av 1,4-dihydropyridiner ved diabetes
DK550683D0 (da) Racematet og den optiske (+)-isomer af den diastereomere alfa-form af 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridin-3,5-dicarboxylsyre-3-(1-benzyl-3-piperidyl)ester-5-methylester og salte deraf samt farmaceutiske praeparater indeholdende disse forbindelser
ATE126190T1 (de) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-
AU575946B2 (en) 1,4-dihydro-2,6-dimethyl-4-(substituted phenyl)- 3,5-dicarboxylate derivatives
SE8303617D0 (sv) 2,6-dimetyl-4-(2,3-diklorfenyl)-1,4-dihydropyridin-3,5-dikarboxylsyra-3-metylester-5-etylester
LV5477A3 (lv) 2,6-Dimetil-3,5-dikarbmetoski-4-(o-difluormetoksifenil)-1,4-dihidropiridina iegusanas panemiens
IT8620305A0 (it) Processo per la preparazione di 2-(n-benzil-n-metilammino)-etil-metil1,4-diidro-2,6-dimetil-4-(3-nitro fenil)-3,5-piridin-dicarbossilato cloridrato.
ATE93851T1 (de) 1,4-dihydropyridin-enantiomere.
RO91076A2 (ro) Procedeu de obtinere a 4-(2'-nitrofenil)-2,6-dimetil-3,5-dicarboximetoxi-1,4-dihidropiridinei
IT8721084A0 (it) Composizioni erbicide che contengono, come antidoto, un derivato nitrilico.

Legal Events

Date Code Title Description
MK1K Patent expired