NO162193C - Radioaktiv steroid, fremgangsmaate ved dets fremst., middel for paavisning in vitro av mottagere for glucocorticoiderog for bestemmelse av antall bindingspunkter for glucocorticoidene og anvendelse av steroidet for dette formaal - Google Patents
Radioaktiv steroid, fremgangsmaate ved dets fremst., middel for paavisning in vitro av mottagere for glucocorticoiderog for bestemmelse av antall bindingspunkter for glucocorticoidene og anvendelse av steroidet for dette formaalInfo
- Publication number
- NO162193C NO162193C NO841797A NO841797A NO162193C NO 162193 C NO162193 C NO 162193C NO 841797 A NO841797 A NO 841797A NO 841797 A NO841797 A NO 841797A NO 162193 C NO162193 C NO 162193C
- Authority
- NO
- Norway
- Prior art keywords
- steroid
- glucocorticoider
- forecast
- receivers
- vitro
- Prior art date
Links
- 239000003862 glucocorticoid Substances 0.000 title abstract 3
- 150000003431 steroids Chemical class 0.000 title abstract 3
- 230000002285 radioactive effect Effects 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 238000000338 in vitro Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- YZCKVEUIGOORGS-NJFSPNSNSA-N Tritium Chemical compound [3H] YZCKVEUIGOORGS-NJFSPNSNSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229940037128 systemic glucocorticoids Drugs 0.000 abstract 2
- 229910052722 tritium Inorganic materials 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/534—Production of labelled immunochemicals with radioactive label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8309811A FR2547587B1 (fr) | 1983-06-14 | 1983-06-14 | Steroides radioactifs, leur procede de preparation, leur application a la mise en evidence des recepteurs de glucocorticoides et au dosage du nombre de sites de fixation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO841797L NO841797L (no) | 1984-12-17 |
| NO162193B NO162193B (no) | 1989-08-14 |
| NO162193C true NO162193C (no) | 1989-11-22 |
Family
ID=9289758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO841797A NO162193C (no) | 1983-06-14 | 1984-05-04 | Radioaktiv steroid, fremgangsmaate ved dets fremst., middel for paavisning in vitro av mottagere for glucocorticoiderog for bestemmelse av antall bindingspunkter for glucocorticoidene og anvendelse av steroidet for dette formaal |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US4664850A (OSRAM) |
| EP (1) | EP0128839B1 (OSRAM) |
| JP (1) | JPS6034987A (OSRAM) |
| AT (1) | ATE43132T1 (OSRAM) |
| CA (2) | CA1222743A (OSRAM) |
| DE (1) | DE3478225D1 (OSRAM) |
| FI (1) | FI83784C (OSRAM) |
| FR (1) | FR2547587B1 (OSRAM) |
| NO (1) | NO162193C (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2592047B1 (fr) * | 1985-12-19 | 1988-03-04 | Roussel Uclaf | Complexes organometalliques de produits steroides ayant une affinite pour les recepteurs progestogene et gluco-corticoide et leur application au dosage des recepteurs hormonaux |
| CA2330611A1 (en) | 1998-05-22 | 1999-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Bifunctional molecules and therapies based thereon |
| US8847766B2 (en) | 2005-04-28 | 2014-09-30 | Proteus Digital Health, Inc. | Pharma-informatics system |
| US9062126B2 (en) | 2005-09-16 | 2015-06-23 | Raptor Pharmaceuticals Inc. | Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof |
| EP2398500B1 (en) | 2009-02-20 | 2019-03-13 | 2-BBB Medicines B.V. | Glutathione-based drug delivery system |
| BRPI1011188B1 (pt) | 2009-05-06 | 2019-10-15 | Laboratory Skin Care, Inc. | Composições de liberação dérmica compreendendo complexos de partículas de agente ativo-fosfato de cálcio e métodos para usar as mesmas |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1465484A (fr) * | 1965-10-27 | 1967-01-13 | Composés stéroïdes du type cétonique | |
| FR2398076A1 (fr) * | 1977-07-19 | 1979-02-16 | Roussel Uclaf | Steroides marques au tritium, leur procede de preparation et leur application pour le dosage et la localisation des recepteurs tissulaires hormonaux des steroides |
| FR2398077A1 (fr) * | 1977-07-19 | 1979-02-16 | Roussel Uclaf | Steroides marques au tritium, leur procede de preparation et leur application pour le dosage et la localisation des recepteurs tissulaires hormonaux des steroides |
| FR2430952A1 (fr) * | 1978-07-13 | 1980-02-08 | Roussel Uclaf | Nouveaux derives acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicament |
-
1983
- 1983-06-14 FR FR8309811A patent/FR2547587B1/fr not_active Expired
-
1984
- 1984-05-04 NO NO841797A patent/NO162193C/no unknown
- 1984-06-13 CA CA000456494A patent/CA1222743A/fr not_active Expired
- 1984-06-13 AT AT84401202T patent/ATE43132T1/de not_active IP Right Cessation
- 1984-06-13 FI FI842397A patent/FI83784C/fi not_active IP Right Cessation
- 1984-06-13 DE DE8484401202T patent/DE3478225D1/de not_active Expired
- 1984-06-13 EP EP84401202A patent/EP0128839B1/fr not_active Expired
- 1984-06-14 US US06/620,457 patent/US4664850A/en not_active Expired - Lifetime
- 1984-06-14 JP JP59120899A patent/JPS6034987A/ja active Granted
-
1985
- 1985-12-19 US US06/797,140 patent/US4865767A/en not_active Expired - Fee Related
-
1987
- 1987-02-17 CA CA000529937A patent/CA1242696A/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6034987A (ja) | 1985-02-22 |
| CA1222743A (fr) | 1987-06-09 |
| FR2547587A1 (fr) | 1984-12-21 |
| FI83784B (fi) | 1991-05-15 |
| NO841797L (no) | 1984-12-17 |
| ATE43132T1 (de) | 1989-06-15 |
| CA1242696A (fr) | 1988-10-04 |
| JPH0460479B2 (OSRAM) | 1992-09-28 |
| FI842397A0 (fi) | 1984-06-13 |
| US4664850A (en) | 1987-05-12 |
| NO162193B (no) | 1989-08-14 |
| EP0128839B1 (fr) | 1989-05-17 |
| FR2547587B1 (fr) | 1985-10-25 |
| EP0128839A2 (fr) | 1984-12-19 |
| EP0128839A3 (en) | 1985-09-18 |
| FI83784C (fi) | 1991-08-26 |
| FI842397L (fi) | 1984-12-15 |
| US4865767A (en) | 1989-09-12 |
| DE3478225D1 (en) | 1989-06-22 |
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