NO156200C - Analogifremgangsmaate ved fremstilling av terapeutisk aktiv ester av diflunisal. - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktiv ester av diflunisal.

Info

Publication number
NO156200C
NO156200C NO824280A NO824280A NO156200C NO 156200 C NO156200 C NO 156200C NO 824280 A NO824280 A NO 824280A NO 824280 A NO824280 A NO 824280A NO 156200 C NO156200 C NO 156200C
Authority
NO
Norway
Prior art keywords
diflunisal
hydrogen
estes
preparation
therapeutic active
Prior art date
Application number
NO824280A
Other languages
English (en)
Norwegian (no)
Other versions
NO156200B (no
NO824280L (no
Inventor
Conrad P Dorn
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NO824280L publication Critical patent/NO824280L/no
Publication of NO156200B publication Critical patent/NO156200B/no
Publication of NO156200C publication Critical patent/NO156200C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00—Preparation of esters of carbonic or haloformic acids
    • C07C68/06—Preparation of esters of carbonic or haloformic acids from organic carbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/10—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/287—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96—Esters of carbonic or haloformic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Dental Preparations (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO824280A 1981-12-21 1982-12-20 Analogifremgangsmaate ved fremstilling av terapeutisk aktiv ester av diflunisal. NO156200C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33242681A 1981-12-21 1981-12-21

Publications (3)

Publication Number Publication Date
NO824280L NO824280L (no) 1983-06-22
NO156200B NO156200B (no) 1987-05-04
NO156200C true NO156200C (no) 1987-08-12

Family

ID=23298179

Family Applications (1)

Application Number Title Priority Date Filing Date
NO824280A NO156200C (no) 1981-12-21 1982-12-20 Analogifremgangsmaate ved fremstilling av terapeutisk aktiv ester av diflunisal.

Country Status (15)

Country Link
EP (1) EP0082404B1 (de)
JP (1) JPS58116440A (de)
KR (1) KR840002766A (de)
AT (1) ATE17941T1 (de)
AU (1) AU563270B2 (de)
CA (1) CA1191153A (de)
DE (1) DE3269109D1 (de)
DK (1) DK562482A (de)
ES (1) ES8401924A1 (de)
FI (1) FI824202L (de)
GR (1) GR77835B (de)
NO (1) NO156200C (de)
NZ (1) NZ202721A (de)
PT (1) PT76003B (de)
ZA (1) ZA829334B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2482587A1 (fr) * 1980-05-14 1981-11-20 Poudres & Explosifs Ste Nale Procede de synthese de chloroformiates a-chlores et nouveaux chloroformiates a-chlores
IL67445A (en) * 1982-12-09 1985-11-29 Teva Pharma Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids
IL67623A (en) * 1983-01-05 1984-09-30 Teva Pharma 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it
FR2551058B1 (fr) * 1983-08-26 1986-09-26 Poudres & Explosifs Ste Nale Procede de preparation de chloroformiates a-chlores
FR2574075B1 (fr) * 1984-12-04 1987-09-18 Poudres & Explosifs Ste Nale Procede de synthese d'esters actifs d'acides carboxyliques, nouveaux carbonates alpha-halogenes utiles pour cette synthese et leur mode d'obtention
AU2003274127A1 (en) 2003-10-08 2005-04-21 Innovaprotean, S.L. Compounds for the treatment of diseases associated with the formation of amyloid fibrils
US7423818B2 (en) * 2005-07-15 2008-09-09 Electro Scientific Industries, Inc. Method of suppressing distortion of a working laser beam of a laser link processing system

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1175212A (en) * 1967-03-09 1969-12-23 Merck & Co Inc Halo-Substituted 5-Phenylbenzoic Acids and their Derivatives

Also Published As

Publication number Publication date
PT76003A (en) 1983-01-01
AU563270B2 (en) 1987-07-02
ZA829334B (en) 1984-07-25
AU9133182A (en) 1983-06-30
DK562482A (da) 1983-06-22
NO156200B (no) 1987-05-04
PT76003B (en) 1985-12-03
FI824202A0 (fi) 1982-12-07
ES518359A0 (es) 1984-01-16
ES8401924A1 (es) 1984-01-16
FI824202L (fi) 1983-06-22
ATE17941T1 (de) 1986-02-15
CA1191153A (en) 1985-07-30
EP0082404A1 (de) 1983-06-29
NO824280L (no) 1983-06-22
JPS58116440A (ja) 1983-07-11
KR840002766A (ko) 1984-07-16
GR77835B (de) 1984-09-25
NZ202721A (en) 1985-12-13
EP0082404B1 (de) 1986-02-12
DE3269109D1 (en) 1986-03-27

Similar Documents

Publication Publication Date Title
NO171680C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktiv morfolinoethylester av mycofenolsyre og derivater derav
NO158539C (no) Analogifremgangsmaate for fremstilling av en terapeutisk aktiv 2,6-diaminopurinforbindelse.
NO156200C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktiv ester av diflunisal.
NO171915C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive 1-azabicyklo(4.2.0)okt-2-en-derivater
IL64073A (en) (2s,5r)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them
FI891845A0 (fi) Foerfarande foer framstaellning av optiskt aktivt 3-(metansulfonyloxi) tiolan och dess analoger.
ATE123487T1 (de) Derivate der kaffeinsäure und sie enthaltende pharmazeutische zusammensetzungen.
IL108432A (en) DERIVATIVES OF 3, 5-DIHYDROXY-7- £1, 2, 6, 7, 8, 8a-HEXAHYDRO-2- METHYL-8- (SUBSTITUTED ALKANOYLOXY)-1-NAPHTHYL| HEPTANOIC ACID AND THEIR LACTONES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
ATE57928T1 (de) 1-alkyl-ergolinyl-thioharnstoffderivate.
FI890929A0 (fi) Foerfarande foer framstaellning av ftalazinaettiksyraesterderivat och ny mellanprodukt.
KR900006287A (ko) 2-[4-(2-피페리디노-에톡시)-벤조일]-벤조산의 측쇄 알킬 에스테르, 이의 제조 방법 및 진경제로서의 이의 용도
ATE92461T1 (de) Gegen die zerebrale insuffizienz wirksame verbindungen.
GB1187340A (en) 4-Benzylpiperidine Derivatives
DK227088A (da) Prodrug-derivater af carboxylsyre-laegemidler