ZA829334B - Novel forms of diflunisal and related compounds - Google Patents

Novel forms of diflunisal and related compounds

Info

Publication number
ZA829334B
ZA829334B ZA829334A ZA829334A ZA829334B ZA 829334 B ZA829334 B ZA 829334B ZA 829334 A ZA829334 A ZA 829334A ZA 829334 A ZA829334 A ZA 829334A ZA 829334 B ZA829334 B ZA 829334B
Authority
ZA
South Africa
Prior art keywords
hydrogen
diflunisal
lower alkyl
related compounds
novel forms
Prior art date
Application number
ZA829334A
Other languages
English (en)
Inventor
Conrad P Dorn
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA829334B publication Critical patent/ZA829334B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00Preparation of esters of carbonic or haloformic acids
    • C07C68/06Preparation of esters of carbonic or haloformic acids from organic carbonates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/10Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/28Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/287Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96Esters of carbonic or haloformic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Dental Preparations (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA829334A 1981-12-21 1982-12-20 Novel forms of diflunisal and related compounds ZA829334B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33242681A 1981-12-21 1981-12-21

Publications (1)

Publication Number Publication Date
ZA829334B true ZA829334B (en) 1984-07-25

Family

ID=23298179

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA829334A ZA829334B (en) 1981-12-21 1982-12-20 Novel forms of diflunisal and related compounds

Country Status (15)

Country Link
EP (1) EP0082404B1 (xx)
JP (1) JPS58116440A (xx)
KR (1) KR840002766A (xx)
AT (1) ATE17941T1 (xx)
AU (1) AU563270B2 (xx)
CA (1) CA1191153A (xx)
DE (1) DE3269109D1 (xx)
DK (1) DK562482A (xx)
ES (1) ES518359A0 (xx)
FI (1) FI824202L (xx)
GR (1) GR77835B (xx)
NO (1) NO156200C (xx)
NZ (1) NZ202721A (xx)
PT (1) PT76003B (xx)
ZA (1) ZA829334B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2482587A1 (fr) * 1980-05-14 1981-11-20 Poudres & Explosifs Ste Nale Procede de synthese de chloroformiates a-chlores et nouveaux chloroformiates a-chlores
IL67445A (en) * 1982-12-09 1985-11-29 Teva Pharma Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids
IL67623A (en) * 1983-01-05 1984-09-30 Teva Pharma 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it
FR2551058B1 (fr) * 1983-08-26 1986-09-26 Poudres & Explosifs Ste Nale Procede de preparation de chloroformiates a-chlores
FR2574075B1 (fr) * 1984-12-04 1987-09-18 Poudres & Explosifs Ste Nale Procede de synthese d'esters actifs d'acides carboxyliques, nouveaux carbonates alpha-halogenes utiles pour cette synthese et leur mode d'obtention
US7265245B2 (en) 2003-10-08 2007-09-04 Innovaprotean, S.L Compounds useful for the treatment of diseases associated with the formation of amyloid fibrils
US7423818B2 (en) * 2005-07-15 2008-09-09 Electro Scientific Industries, Inc. Method of suppressing distortion of a working laser beam of a laser link processing system

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1175212A (en) * 1967-03-09 1969-12-23 Merck & Co Inc Halo-Substituted 5-Phenylbenzoic Acids and their Derivatives

Also Published As

Publication number Publication date
ES8401924A1 (es) 1984-01-16
KR840002766A (ko) 1984-07-16
NO824280L (no) 1983-06-22
DK562482A (da) 1983-06-22
DE3269109D1 (en) 1986-03-27
NO156200B (no) 1987-05-04
NZ202721A (en) 1985-12-13
ES518359A0 (es) 1984-01-16
CA1191153A (en) 1985-07-30
ATE17941T1 (de) 1986-02-15
AU9133182A (en) 1983-06-30
PT76003B (en) 1985-12-03
FI824202A0 (fi) 1982-12-07
JPS58116440A (ja) 1983-07-11
AU563270B2 (en) 1987-07-02
EP0082404B1 (en) 1986-02-12
EP0082404A1 (en) 1983-06-29
GR77835B (xx) 1984-09-25
NO156200C (no) 1987-08-12
PT76003A (en) 1983-01-01
FI824202L (fi) 1983-06-22

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