NO155240C - Analogifremgangsmaate for fremstilling av terapeutisk aktive aroyl (propionyl- eller butyryl)-l-prolinderivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive aroyl (propionyl- eller butyryl)-l-prolinderivater.

Info

Publication number
NO155240C
NO155240C NO792849A NO792849A NO155240C NO 155240 C NO155240 C NO 155240C NO 792849 A NO792849 A NO 792849A NO 792849 A NO792849 A NO 792849A NO 155240 C NO155240 C NO 155240C
Authority
NO
Norway
Prior art keywords
aroyl
butyryl
propionyl
preparation
therapeutic active
Prior art date
Application number
NO792849A
Other languages
English (en)
Norwegian (no)
Other versions
NO792849L (no
NO155240B (no
Inventor
Francis Joseph Mcevoy
Jay Donald Albright
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/044,733 external-priority patent/US4226775A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NO792849L publication Critical patent/NO792849L/no
Publication of NO155240B publication Critical patent/NO155240B/no
Publication of NO155240C publication Critical patent/NO155240C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/84Unsaturated compounds containing keto groups containing six membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/88Unsaturated compounds containing keto groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
NO792849A 1978-09-05 1979-09-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive aroyl (propionyl- eller butyryl)-l-prolinderivater. NO155240C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93956478A 1978-09-05 1978-09-05
US06/044,733 US4226775A (en) 1979-06-01 1979-06-01 Substituted thio-substituted benzyl-propionyl-L-prolines

Publications (3)

Publication Number Publication Date
NO792849L NO792849L (no) 1980-03-06
NO155240B NO155240B (no) 1986-11-24
NO155240C true NO155240C (no) 1987-03-04

Family

ID=26721935

Family Applications (1)

Application Number Title Priority Date Filing Date
NO792849A NO155240C (no) 1978-09-05 1979-09-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive aroyl (propionyl- eller butyryl)-l-prolinderivater.

Country Status (19)

Country Link
EP (1) EP0010347B1 (nl)
AR (2) AR230624A1 (nl)
AU (1) AU530456B2 (nl)
CA (1) CA1114821A (nl)
DD (1) DD147236A5 (nl)
DE (1) DE2934592A1 (nl)
DK (1) DK161198C (nl)
ES (1) ES483846A1 (nl)
FI (1) FI75152C (nl)
GR (1) GR73190B (nl)
HU (1) HU180651B (nl)
IE (1) IE48939B1 (nl)
IL (1) IL57802A (nl)
NO (1) NO155240C (nl)
NZ (1) NZ190995A (nl)
PH (1) PH19468A (nl)
PT (1) PT70025A (nl)
YU (1) YU205479A (nl)
ZA (1) ZA793536B (nl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE51409B1 (en) * 1980-07-24 1986-12-24 Ici Ltd Amide derivatives
DE3169110D1 (en) * 1980-11-24 1985-03-28 Ici Plc Amide derivatives
JPH0623190B2 (ja) * 1985-04-16 1994-03-30 サントリー株式会社 インヒビタ−活性を有するn−アシルピロリジン誘導体及びその製法並びに用途
US4880827A (en) * 1986-03-18 1989-11-14 Sumitomo Pharmaceuticals Company, Ltd. Pyrrolidine derivatives having inhibitory action for proline specific endopepidase
HU198012B (en) * 1987-07-03 1989-07-28 Richter Gedeon Vegyeszet Process for producing cyclic amino-acid derivatives and pharmaceutical compositions containing them
CA2113288A1 (en) * 1993-01-29 1994-07-30 Kan Takamine Process for producing aromatic amide compounds
DE4302957A1 (de) * 1993-02-03 1994-08-04 Bayer Ag Imidazolyl-substituierte Phenylessigsäureprolinamide
AU693110B2 (en) * 1993-08-19 1998-06-25 Warner-Lambert Company Substituted 2(5H)furanone, 2(5H)thiophenone and 2(5H)pyrrolone derivatives, their preparation and their use as endothelin antagonists
US5922759A (en) * 1996-06-21 1999-07-13 Warner-Lambert Company Butenolide endothelin antagonists
AU6603996A (en) * 1995-08-24 1997-03-19 Warner-Lambert Company Furanone endothelin antagonists
US5891892A (en) * 1996-10-29 1999-04-06 Warner-Lambert Company Small molecule biaryl compounds as inhibitors of endothelin converting enzyme

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4052511A (en) * 1976-02-13 1977-10-04 E. R. Squibb & Sons, Inc. Carboxyacylproline derivatives
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4116962A (en) * 1976-12-03 1978-09-26 E. R. Squibb & Sons, Inc. Pyrrolidine and piperidine-2-carboxylic acid derivatives

Also Published As

Publication number Publication date
YU205479A (en) 1983-01-21
EP0010347A1 (en) 1980-04-30
AU4935179A (en) 1980-03-13
DK369079A (da) 1980-03-06
NZ190995A (en) 1982-03-09
FI792595A (fi) 1980-03-06
ES483846A1 (es) 1980-04-16
FI75152B (fi) 1988-01-29
IL57802A (en) 1983-05-15
IE791682L (en) 1980-03-05
GR73190B (nl) 1984-02-14
PH19468A (en) 1986-05-14
AU530456B2 (en) 1983-07-14
PT70025A (en) 1979-09-01
EP0010347B1 (en) 1983-11-09
NO792849L (no) 1980-03-06
ZA793536B (en) 1980-07-30
IE48939B1 (en) 1985-06-26
FI75152C (fi) 1988-05-09
DE2934592C2 (nl) 1989-10-05
CA1114821A (en) 1981-12-22
DE2934592A1 (de) 1980-03-20
DD147236A5 (de) 1981-03-25
NO155240B (no) 1986-11-24
AR229953A1 (es) 1984-01-31
DK161198C (da) 1991-12-02
DK161198B (da) 1991-06-10
AR230624A1 (es) 1984-05-31
HU180651B (en) 1983-04-29
IL57802A0 (en) 1979-11-30

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