NO154797B - ANALOGY PROCEDURE FOR THE PREPARATION OF CEPHALOSPOR COMPOUNDS IN THE SYN-ISOMER FORM OR TOXIC SALTS THEREOF - Google Patents

ANALOGY PROCEDURE FOR THE PREPARATION OF CEPHALOSPOR COMPOUNDS IN THE SYN-ISOMER FORM OR TOXIC SALTS THEREOF Download PDF

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Publication number
NO154797B
NO154797B NO721705A NO170572A NO154797B NO 154797 B NO154797 B NO 154797B NO 721705 A NO721705 A NO 721705A NO 170572 A NO170572 A NO 170572A NO 154797 B NO154797 B NO 154797B
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sulfuric acid
concentrated sulfuric
radioactive
cephalospor
syn
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NO721705A
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Norwegian (no)
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NO154797C (en
Inventor
Martin Christopher Cook
Gordon Ian Gregory
Janice Bradshaw
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Glaxo Lab Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/42—Singly bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/14—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)

Description

Fremgangsmåte til destruksjon av med radioaktivt stoff forurenset celluloseholdig materiale ved hjelp av konsentrert svovelsyre. Method for the destruction of cellulosic material contaminated with radioactive substances using concentrated sulfuric acid.

På steder hvor man arbeider med radioaktive stoffer forekommer ofte avfall In places where you work with radioactive substances, waste often occurs

i form av celluloseholdig materiale som er in the form of cellulosic material which is

forurenset med radioaktivt stoff. Dette celluloseholdige materiale destrueres i almin-nelighet således at det radioaktive stoff contaminated with radioactive material. This cellulose-containing material is generally destroyed so that the radioactive substance

kan isoleres i konsentrert tilstand for se-nere håndtering og oppbevaring. can be isolated in a concentrated state for later handling and storage.

Man har hittil destruert det celluloseholdige materiale ved å forbrenne det i en Until now, the cellulose-containing material has been destroyed by burning it in a

ovn. Denne metode lider imidlertid av den furnace. However, this method suffers from it

ulempe at en del av det radioaktive stoff disadvantage that part of the radioactive substance

føres bort med røken i form av svevepartikler hvilket bevirker at man må anvende is carried away with the smoke in the form of suspended particles, which means that you have to use

særlige luftrensningsanlegg for å befri avgangsgassen for de radioaktive partikler. special air purification facilities to free the exhaust gas of the radioactive particles.

Hertil kommer at forekomsten av radioaktive svevepartikler generelt øker risikoen In addition, the presence of radioactive suspended particles generally increases the risk

ved destruksjonsprosessen. by the destruction process.

Det er videre foreslått å destruere det It is further proposed to destroy it

celluloseholdige materiale ved hjelp av cellulosic material by means of

konsentrert svovelsyre etter det fra Kjel-dahlanalyser kjente prinsipp. Man har her concentrated sulfuric acid according to the principle known from Kjel-dahl analyses. One has here

gått frem på den måte at man har helt proceeded in such a way that one has completely

kald konsentrert svovelsyre på det celluloseholdige materiale hvoretter man har oppvarmet svovelsyre, som inneholder en ok-sydasjonskatalysator, til omkring dens ko-kepunkt. På denne måte kan man imidlertid kun destruere meget små mengder celluloseholdig materiale i forhold til den an-vendte mengde svovelsyre. Tilsetningen av cold concentrated sulfuric acid on the cellulose-containing material after which sulfuric acid, which contains an oxidation catalyst, has been heated to around its boiling point. In this way, however, only very small amounts of cellulose-containing material can be destroyed in relation to the amount of sulfuric acid used. The addition of

større mengder bevirker nemlig at mate- larger quantities mean that feed-

rialet ved oppvarmning baker seg sammen likesom en kraftig røkutvikling finner sted. Heller ikke en tilsetning av det celluloseholdige materiale til den varme svovelsyren er mulig uten kraftig røkutvikling. Som følge herav har man avvist destruksjon av det celluloseholdige materiale med konsentrert svovelsyre som ugjennomførlig i industriell praksis. the rial on heating bakes together just as a strong smoke development takes place. Neither is an addition of the cellulose-containing material to the hot sulfuric acid possible without strong smoke generation. As a result, destruction of the cellulose-containing material with concentrated sulfuric acid has been rejected as impracticable in industrial practice.

Det er formålet med foreliggende opp-finnelse å tilveiebringe en fremgangsmåte til destruksjon av med radioaktivt stoff forurenset celluloseholdig materiale ved hjelp av konsentrert svovelsyre, hvilken fremgangsmåte kan gjennomføres industri-elt uten vesentlig risiko for dannelse av radioaktive svevepartikler. It is the purpose of the present invention to provide a method for the destruction of cellulosic material contaminated with radioactive substances by means of concentrated sulfuric acid, which method can be carried out industrially without significant risk of the formation of radioactive suspended particles.

Dette formål oppnås ved at materialet oppslemmes i kald konsentrert svovelsyre, hvoretter oppslemningen ledes ned under overflaten av konsentrert svovelsyre, som holdes ved en temperatur på 300—330°C, og hvortil det på i og for seg kjent måte er tilsatt en katalysator for oksydering av det celluloseholdige materiale til karbondioksyd og vann. This purpose is achieved by slurrying the material in cold concentrated sulfuric acid, after which the slurry is led down below the surface of concentrated sulfuric acid, which is kept at a temperature of 300-330°C, and to which a catalyst for oxidation is added in a manner known per se of the cellulosic material to carbon dioxide and water.

Det viser seg at destruksjon i dette tilfelle forløper uten utvikling av røk, og at avgangsgassen, som består av karbondioksyd og svoveldioksyd og som inneholder vanndamp og svovelsyredamp, kun med-river en liten mengde dråpeformet stoff av den størrelsesorden som vanligvis medrives ved en destillasjon. Den lave mengde radioaktivt stoff som på denne måte kan unnvike fra destruksjonsbeholderen er ikke til vesentlig genanse, idet den lett kan til-bakeholdes i passende kolonner eller dråpe-fangere og for øvrig utfelles med den svovelsyre som kan kondenseres i en etter destruksjonsbeholderen anbragte konden-sator. It turns out that destruction in this case proceeds without the development of smoke, and that the waste gas, which consists of carbon dioxide and sulfur dioxide and which contains water vapor and sulfuric acid vapor, only entrains a small amount of drop-shaped material of the order of magnitude that is usually entrained in a distillation. The small amount of radioactive material that can escape from the destruction container in this way is not of any significant concern, as it can easily be retained in suitable columns or droplet traps and otherwise precipitated with the sulfuric acid that can be condensed in a condenser placed after the destruction container. sator.

Fremgangsmåten ifølge oppfinnelsen skal i det følgende nærmere belyses i for-bindelse med et eksempel: 5 kg celluloseholdig materiale som er forurenset med radioaktivt stoff, røres ut med 50 1 kald konsentrert svovelsyre til dannelse av en oppslemning. Denne pum-pes i løpet av 1 time gjennom et rør ned under overflaten av 100 1 konsentrert svovelsyre, hvortil det som katalysator er tilsatt 1 kg selen. Den sistnevnte konsentrerte svovelsyre, som er anbragt i en luk-ket kvartsbeholder forsynt med destilla-sjonsoppsats, holdes oppvarmet til 310°C. Under destruksjon av det celluloseholdige materiale bortgår ca. 50 kg svovelsyre, 8 kg karbondioksyd, 24 kg svoveldioksyd og 12 kg vanndamp. Det iakttas ikke noen røk-utvikling over den varme konsentrerte svo-velsyres overflate, og hovedmengden av radioaktivt stoff forblir i svovelsyren i destruksjonsbeholderen og kan isoleres fra denne i konsentrert tilstand ved inndamp-ning av svovelsyren hvorved det radioaktive stoff blir tilbake som inndampnings-rest. The method according to the invention will be explained in more detail in the following in connection with an example: 5 kg of cellulose-containing material which is contaminated with radioactive material is stirred with 50 1 of cold concentrated sulfuric acid to form a slurry. This is pumped over the course of 1 hour through a pipe below the surface of 100 1 of concentrated sulfuric acid, to which 1 kg of selenium has been added as a catalyst. The latter concentrated sulfuric acid, which is placed in a closed quartz container equipped with a distillation apparatus, is kept heated to 310°C. During destruction of the cellulose-containing material, approx. 50 kg sulfuric acid, 8 kg carbon dioxide, 24 kg sulfur dioxide and 12 kg water vapour. No smoke development is observed over the surface of the hot concentrated sulfuric acid, and the main amount of radioactive material remains in the sulfuric acid in the destruction container and can be isolated from it in a concentrated state by evaporation of the sulfuric acid, whereby the radioactive material remains as an evaporation residue .

Avgangsgassen kan etter kondensasjon The exhaust gas can after condensation

av svovelsyredamp og fjernelse av over-skytende vann behandles på kjent måte til gjendannelse av svovelsyre av svoveldioksyd, således at kun karbondioksyd unnviker. Den kondenserte og den gjenvunne svovelsyre som kan inneholde en liten mengde radioaktivt stoff, kan etter avkjøling be-nyttes til oppløsning av ytterligere mengder celluloseholdig materiale, og prosessen kan gjennomføres i kontinuert drift inntil det anses for formålstjenlig å inndampe svovelsyren helt for isolering av radioaktivt stoff. of sulfuric acid vapor and removal of excess water is treated in a known manner to regenerate sulfuric acid from sulfur dioxide, so that only carbon dioxide escapes. The condensed and recovered sulfuric acid, which may contain a small amount of radioactive material, can, after cooling, be used to dissolve further quantities of cellulose-containing material, and the process can be carried out in continuous operation until it is considered expedient to evaporate the sulfuric acid completely for the isolation of radioactive material .

Claims (1)

Fremgangsmåte til destruksjon av med radioaktivt stoff forurenset celluloseholdig materiale ved hjelp av konsentrert svovelsyre under oppvarmning til om lag ko-kepunktet, karakterisert ved at materialet etter oppslemming i kald konsentrert svovelsyre ledes ned under overflaten av konsentrert svovelsyre, som holdes ved en temperatur på 300—330°C, og hvortil det på i og for seg kjent måte er tilsatt en katalysator for oksydering av det celluloseholdige materiale til karbondioksyd og vann. Anførte publikasjoner:Method for the destruction of cellulosic material contaminated with radioactive substances using concentrated sulfuric acid while heating to approximately the boiling point, characterized in that the material, after being suspended in cold concentrated sulfuric acid, is led down below the surface of concentrated sulfuric acid, which is kept at a temperature of 300- 330°C, and to which a catalyst for oxidizing the cellulose-containing material to carbon dioxide and water is added in a manner known per se. Cited publications: N. C. Franz Radioactive Waste materials in Wood Industries Forest Products Journal no. 3 (March 1963).N. C. Franz Radioactive Waste materials in Wood Industries Forest Products Journal no. 3 (March 1963).
NO721705A 1971-05-14 1972-05-12 ANALOGY PROCEDURE FOR THE PREPARATION OF CEPHALOSPOR COMPOUNDS IN THE SYN-ISOMER FORM OR TOXIC SALTS THEREOF NO154797C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1508271A GB1399086A (en) 1971-05-14 1971-05-14 Cephalosporin compounds
GB4588471 1971-10-01

Publications (2)

Publication Number Publication Date
NO154797B true NO154797B (en) 1986-09-15
NO154797C NO154797C (en) 1986-12-29

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JP (3) JPS531280B1 (en)
AT (1) AT336786B (en)
BE (1) BE783449A (en)
CA (1) CA1027554A (en)
CH (1) CH591497A5 (en)
CS (2) CS245753B2 (en)
CY (1) CY971A (en)
DE (2) DE2223375C2 (en)
DK (1) DK155187C (en)
ES (2) ES402651A1 (en)
FR (2) FR2137900B1 (en)
GB (1) GB1399086A (en)
HK (1) HK66078A (en)
IE (1) IE38172B1 (en)
IL (1) IL39429A (en)
KE (1) KE2895A (en)
MY (1) MY7800466A (en)
NL (1) NL166688C (en)
NO (1) NO154797C (en)
PH (1) PH11205A (en)
SE (1) SE457795B (en)
YU (2) YU41807B (en)

Families Citing this family (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1445979A (en) * 1972-10-25 1976-08-11 Glaxo Lab Ltd Cephalosporin derivatives
US4079178A (en) * 1971-05-14 1978-03-14 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino) acylamido groups at the 7-position
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US4138555A (en) 1971-05-14 1979-02-06 Glaxo Laboratories, Limited (6R,7R)-7-[2-aryl-2-(etherified oximino)acetamido]-3-carbamoyloxymethylceph-3-em-4-carboxylic acid 1-oxides
US4064346A (en) * 1971-05-14 1977-12-20 Glaxo Laboratories Limited 3-Acetoxymethyl-7β-(2-carboxy-methoxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof
US4033950A (en) * 1971-05-14 1977-07-05 Glaxo Laboratories Limited 3-Hydroxymethyl-7β-(2-alkoxy-or benzyloxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof
AR207341A1 (en) * 1973-03-15 1976-09-30 Fujisawa Pharmaceutical Co A PROCEDURE FOR THE PREPARATION OF 2-ALKYL-2 OR 3-CEFEM-4-CARBOXYL ACID DERIVATIVES
DE2460537C2 (en) * 1973-12-21 1987-01-22 Glaxo Laboratories Ltd., Greenford, Middlesex 7-β-Acylamido-3-em-4-carboxylic acid antibiotics
US4144392A (en) 1973-12-21 1979-03-13 Glaxo Laboratories Limited Cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyimino-arylacetamido group and at position-3 the residue of a sulphur nucleophile
US4144393A (en) 1973-12-21 1979-03-13 Glaxo Laboratories Limited 3-Acetoxymethyl cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyiminoarylacetamido group
GB1512957A (en) * 1974-08-23 1978-06-01 Glaxo Lab Ltd Gephalosporin antibiotics
DK154939C (en) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd METHOD OF ANALOGUE FOR THE PREPARATION OF THIAZOLYLACETAMIDO-CEPHEM COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE SALTS OR ESTERS THEREOF
US4200746A (en) 1974-12-20 1980-04-29 Glaxo Laboratories, Ltd. Cephalosporins
GB1522140A (en) * 1974-12-20 1978-08-23 Glaxo Lab Ltd Syn-7-(2-hydroxyiminoacetamido)-3-pyridiniummethyl cephalosporins methods for their preparation and compositions containing them
PH15487A (en) * 1975-02-04 1983-01-31 Fujisawa Pharmaceutical Co 7((2-hydroxyamino-2-disubstituted phenyl-acetamido)-)3-heterocyclithio-3-cephem-4-carboxylic acids
GB1555471A (en) * 1975-06-19 1979-11-14 Glaxo Lab Ltd 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof
SE440655B (en) * 1976-01-23 1985-08-12 Roussel Uclaf SET TO MAKE NEW OXIME DERIVATIVES OF 7-AMINO-THIAZOLYL-ACETAMIDO-CEPHALOSPORANIC ACID
DE2760123C2 (en) 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporanic acids, their preparation and pharmaceutical compositions containing them
IE44888B1 (en) * 1976-03-09 1982-05-05 Fujisawa Pharmaceutical Co 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation theroef
GB1575803A (en) 1976-03-09 1980-10-01 Fujisawa Pharmaceutical Co 3,7 disubstituted 3 cephem 4 carboxylic acid compounds andprocesses for the preparation thereof
US4165430A (en) 1976-03-19 1979-08-21 Glaxo Laboratories Limited Cephalosporins having a 7-carboxy substituted α-etherified oximinoarylacetamido) group
FR2345153A1 (en) * 1976-03-25 1977-10-21 Roussel Uclaf NEW ALCOYLOXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
DK162391C (en) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co ANALOGY PROCEDURE FOR PREPARING SYN-ISOMERS OF 3,7-DISUBSTITUTED 3-CEPHEM-4-CARBOXYLIC ACID COMPOUNDS
DE2760484C2 (en) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid
US4278670A (en) * 1976-07-12 1981-07-14 Smithkline Corporation 7-Alpha-oxyiminoacylcephalosporins
FR2361895A1 (en) * 1976-08-20 1978-03-17 Roussel Uclaf NEW OXIMES DERIVED FROM 3-CARBAMOYLOXYMETHYL 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
GB1592149A (en) * 1976-10-08 1981-07-01 Fujisawa Pharmaceutical Co 3 7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for preparation thereof
FR2381053A1 (en) * 1977-02-18 1978-09-15 Roussel Uclaf NEW OXIMES DERIVED FROM 3-THIADIAZOLYL THIOMETHYL 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
JPS53103493A (en) * 1977-02-18 1978-09-08 Takeda Chem Ind Ltd Cephalosporin derivatives and process for their preparation
PH17188A (en) 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
SE439312B (en) 1977-03-25 1985-06-10 Roussel Uclaf SET TO MAKE NEW OXIME DERIVATIVES OF 3-ACETOXIMETHYL-7-AMINOTIAZOLYLACETAMIDO CEPHALOSPORANIC ACID
FR2384779A1 (en) * 1977-03-25 1978-10-20 Roussel Uclaf NEW OXIMES DERIVED FROM 3-CHLORO OR 3-METHOXY 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
DE2716677C2 (en) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephem derivatives and processes for their preparation
DE2714880A1 (en) * 1977-04-02 1978-10-26 Hoechst Ag CEPHEMDER DERIVATIVES AND PROCESS FOR THEIR PRODUCTION
NL7805715A (en) * 1977-06-03 1978-12-05 Hoffmann La Roche METHOD FOR PREPARING ACYL DERIVATIVES.
IT1192287B (en) * 1977-11-14 1988-03-31 Fujisawa Pharmaceutical Co PHARMACEUTICAL ACTION DERIVATIVES OF CEPHALOSPORANIC ACID AND RELATED PREPARATION PROCEDURE
FR2438051A2 (en) * 1978-10-05 1980-04-30 Roussel Uclaf 3-Azido:methyl-3-cephem-4-carboxylic acid derivs. - useful as broad-spectrum antibacterial agents and disinfectants (BE 15.10.79)
SE445350B (en) * 1978-04-14 1986-06-16 Roussel Uclaf OXIMO DERIVATIVES OF 3-AZIDOMETHYL-7-AMINO-THIAZOLYL-ACETAMIDO-CEPHALOSPORANIC ACID AND ITS USE AS ANTIBIOTICS
DE2822861A1 (en) * 1978-05-26 1979-11-29 Hoechst Ag CEPHEMDER DERIVATIVES AND PROCESS FOR THEIR PRODUCTION
AR228726A1 (en) * 1978-05-26 1983-04-15 Glaxo Group Ltd PROCEDURE FOR THE PREPARATION OF ANTIBIOTIC (6R, 7R) -7 - ((Z) -2- (2-AMINOTIAZOL-4-IL) -2- (2-CARBOXIPROP-2-OXIIMINO) ACETAMIDO) -3- (1- PIRIDINIOMETIL) CEF-3-EM-4-CARBOXILATO
DE2822860A1 (en) * 1978-05-26 1979-11-29 Hoechst Ag CEPHEM DERIVATIVES AND METHOD FOR THEIR PRODUCTION
US4268509A (en) * 1978-07-10 1981-05-19 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
AT366387B (en) * 1978-11-15 1982-04-13 Glaxo Group Ltd METHOD FOR PRODUCING NEW CEPHALOSPORINE ANTIBIOTICS
DE2914327A1 (en) * 1979-04-09 1980-10-30 Hoechst Ag CEPHEM DERIVATIVES AND METHOD FOR THEIR PRODUCTION
DE3069560D1 (en) * 1979-09-03 1984-12-06 Fujisawa Pharmaceutical Co Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
US4341777A (en) * 1979-09-10 1982-07-27 Glaxo Group Limited Cephalosporin antibiotic
DE3069364D1 (en) * 1979-10-12 1984-11-08 Fujisawa Pharmaceutical Co Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
EP0076528B1 (en) * 1980-02-18 1990-05-23 Roussel-Uclaf Oxime derivatives of 3-alkyloxy or 3-alkylthiomethyl 7-amino-thiazolylacetamido-cephalosporanic acid and their preparation
FR2476087A1 (en) * 1980-02-18 1981-08-21 Roussel Uclaf NOVEL OXIMES DERIVED FROM 3-ALKYLOXY OR 3-ALKYL-THIOMETHYL 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS
EP0037797A3 (en) * 1980-03-11 1981-12-16 Ciba-Geigy Ag Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application
ZA813787B (en) * 1980-06-18 1982-07-28 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
GR75644B (en) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co
IL63207A (en) * 1980-07-24 1985-09-29 Lonza Ag Process for the preparation of 2-(2-aminothiazole-4-yl)-2-(syn)-methoxyiminoacetic acid esters
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE3175156D1 (en) * 1980-08-29 1986-09-25 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
US4416879A (en) * 1980-09-08 1983-11-22 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
NZ198350A (en) * 1980-09-25 1985-02-28 Toyama Chemical Co Ltd Cephalosporins and intermediates;pharmaceutical compositions
IL63965A (en) * 1980-10-10 1985-01-31 Sparamedica Ag 7-(2-(2-amino-4-selenazoyl)acetamido)cephalosporin derivatives,and intermediates therefor,their preparation and pharmaceutical compositions containing them
FR2494279A1 (en) * 1980-11-20 1982-05-21 Rhone Poulenc Ind NEW OXACEPHALOSPORINS, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM
FR2494274A2 (en) * 1980-11-20 1982-05-21 Rhone Poulenc Ind NEW THIOVINYL-3 CEPHALOSPORINS, THEIR PREPARATION AND THE MEDICINES THAT CONTAIN THEM
FR2494275A2 (en) * 1980-11-20 1982-05-21 Rhone Poulenc Ind NEW DERIVATIVES OF VINYL-3 CEPHALOSPORINS AND THEIR PREPARATION
FR2494276A2 (en) * 1980-11-20 1982-05-21 Rhone Poulenc Ind NEW VINYL-3 CEPHALOSPORINS, AND THEIR PREPARATION
FR2494280A1 (en) * 1980-11-20 1982-05-21 Rhone Poulenc Ind NEW DERIVATIVES OF CEPHALOSPORINE AND THEIR PREPARATION
GR76342B (en) * 1981-02-02 1984-08-06 Fujisawa Pharmaceutical Co
FR2499995A1 (en) * 1981-02-13 1982-08-20 Roussel Uclaf 7-2-2-Amino-4-thiazolyl 2-hydroxy:imino-acetamido 3-cephem derivs. - 3-substd. by alkoxy- or alkyl-thio-methyl are antibiotics active against gram positive and gram negative bacteria
JPS6011917B2 (en) * 1981-04-09 1985-03-28 山之内製薬株式会社 Novel cephalosporin compounds
FR2505339A1 (en) * 1981-05-11 1982-11-12 Rhone Poulenc Sante 3-Substd. thio-vinyl 1-oxa-ceph-3-em-4-carboxylic acid antibacterials - esp. having 7-2-2-amino-4-thiazolyl-2-methoxy:imino-acetamido Gp., 3-thio substits. include thiadiazolyl and triazinyl Gps.
FR2505338A1 (en) * 1981-05-11 1982-11-12 Rhone Poulenc Sante 3-Substd. thio-vinyl 1-oxa-ceph-3-em-4-carboxylic acid antibacterials - esp. having 7-2-2-amino-4-thiazolyl-2-methoxy:imino-acetamido Gp., 3-thio substits. include thiadiazolyl and triazinyl Gps.
EP0070803A3 (en) * 1981-07-16 1984-05-02 Ciba-Geigy Ag Antibiotically active aminotriazolylcephalosporin derivatives and their preparation
PL238158A1 (en) * 1981-09-08 1984-11-19 Lilly Co Eli Method of obtaining new cephalosporin derivatives
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
JPS5859992A (en) * 1981-09-14 1983-04-09 Fujisawa Pharmaceut Co Ltd Novel cephen compound, its preparation and preventing agent and remedy for microbism
MA19602A1 (en) * 1981-09-30 1983-04-01 Ciba Geigy Ag AMINO-OXAZOLYL COMPOUNDS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS, AND THEIR APPLICATION
US4401668A (en) * 1981-10-02 1983-08-30 Eli Lilly And Company Pyrazinium substituted cephalosporins
US4394503A (en) 1981-12-07 1983-07-19 Bristol-Myers Company Cephalosporin derivatives
US4474954A (en) * 1981-12-07 1984-10-02 Bristol-Myers Company Intermediates for cephalosporin derivatives
US4406899A (en) 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
US4457929A (en) * 1982-03-29 1984-07-03 Bristol-Myers Company 3-Quaternary ammonium methyl)-substituted cephalosporin derivatives
PH19163A (en) * 1982-04-06 1986-01-16 Daiichi Seiyaku Co Cephalosporin derivatives
US4500526A (en) * 1982-06-28 1985-02-19 Bristol-Myers Company Cephalosporin derivatives
ATE30724T1 (en) 1982-06-28 1987-11-15 Bristol Myers Co CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
GB2125033B (en) * 1982-07-23 1985-08-29 Servipharm Ltd Cephalosporins
IE55406B1 (en) * 1982-08-07 1990-09-12 Tanabe Seiyaku Co Novel cephalosporin compounds and preparation thereof
US4546101A (en) * 1982-09-10 1985-10-08 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof
FR2533216A1 (en) * 1982-09-22 1984-03-23 Toyama Chemical Co Ltd New cephalosporins and their salts.
JPS5973043A (en) * 1982-10-19 1984-04-25 House Food Ind Co Ltd Method for modifying quality of hardly soluble gelling agent
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
US4482553A (en) * 1983-04-12 1984-11-13 Eli Lilly And Company Benzothienylglycyl cephalosporin derivatives
US4492694A (en) * 1983-04-12 1985-01-08 Eli Lilly And Company Indolylglycyl cephalosporin derivatives
US4492693A (en) * 1983-04-12 1985-01-08 Eli Lilly And Company Benzothienylglycyl cephalosporin derivatives
GB2137993A (en) * 1983-04-12 1984-10-17 Lilly Co Eli Improvements in or relating to naphthylglycyl cephalosporin derivatives
DE3330605A1 (en) * 1983-08-25 1985-03-14 Hoechst Ag, 6230 Frankfurt CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
JPS60132983A (en) * 1983-12-21 1985-07-16 Tanabe Seiyaku Co Ltd Thiazoleacetic acid derivative and its production
JPS60190783A (en) * 1983-12-21 1985-09-28 Sumitomo Seiyaku Kk Cephem compound
DE3485860T2 (en) * 1983-12-29 1993-01-14 Mochida Pharm Co Ltd CEPHALOSPORINE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS.
JPS60142987A (en) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd Cephalosporin derivative
GB8411954D0 (en) * 1984-05-10 1984-06-13 Glaxo Group Ltd Cephalosporin antibiotics
FI851934L (en) * 1984-05-30 1985-12-01 Ici Plc KEFALOSPORINDERIVAT.
IE58487B1 (en) * 1984-09-07 1993-09-22 Kaisha Maiji Seika New cephalosporin compounds and the production thereof
EP0182633A3 (en) * 1984-11-20 1987-09-02 Ici Pharma Cephalosporin derivatives
JPS61145186A (en) * 1984-12-20 1986-07-02 Meiji Seika Kaisha Ltd Novel cephem compound and preparation thereof
DE3585434D1 (en) * 1984-12-27 1992-04-02 Banyu Pharma Co Ltd CEPHALOSPORINE COMPOUNDS.
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US4874856A (en) * 1985-06-24 1989-10-17 Bristol-Myers Company 3-(substituted)propenyl-7-(aminothiazolylacetamido) ceph-3-em-4-carboxylic acids and esters thereof
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
US4814328A (en) * 1986-03-19 1989-03-21 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, and antibacterial agents
DE3623921A1 (en) * 1986-07-16 1988-01-21 Basf Ag OXIMETHER AND FUNGICIDES CONTAINING THEM
ZA877987B (en) * 1986-11-12 1988-08-31 Ici Pharma Antibiotic compounds
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
JPS63132893A (en) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd Novel cephalosporin derivative, production thereof and antibacterial agent containing said derivative as active ingredient
EP0272827A3 (en) * 1986-12-23 1990-02-07 ZENECA Pharma S.A. 3-heterocyclicthiomethyl cephalosphorins
US5262410A (en) * 1986-12-23 1993-11-16 Ici Pharma 3-heterocyclic thiomethyl cephalosporins
US5189157A (en) * 1987-06-16 1993-02-23 Hoffmann La Roche Inc. Antibacterial cephalosporin compounds
DE3854804T2 (en) * 1987-07-23 1996-06-13 Zeneca Pharma Sa Cephalosporin compounds, processes for their preparation and pharmaceutical preparations containing them
ATE130299T1 (en) * 1987-07-23 1995-12-15 Zeneca Pharma Sa CEPHALOSPORIN COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME.
KR900006811B1 (en) * 1988-05-11 1990-09-21 주식회사 럭 키 Cephalosphorin derivatives and its process
US5202315A (en) * 1989-05-11 1993-04-13 Lucky, Ltd. Cephalosporin compounds
GB8927871D0 (en) * 1989-12-08 1990-02-14 Beecham Group Plc Novel compounds
IN189046B (en) 1998-03-30 2002-12-14 Ranbaxy Lab Ltd
AU2820700A (en) * 1999-03-09 2000-09-28 Ranbaxy Laboratories Limited Process for the preparation of cefuroxime

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE311519B (en) * 1962-12-14 1969-06-16 Astra Ab
GB1208015A (en) * 1967-03-23 1970-10-07 Glaxo Lab Ltd Cephalosporins
GB1208014A (en) * 1967-03-23 1970-10-07 Glaxo Lab Ltd Cephalosporins
GB1241657A (en) * 1967-08-21 1971-08-04 Glaxo Lab Ltd Improvements in or relating to cephalosporin compounds
GB1279402A (en) * 1968-06-14 1972-06-28 Glaxo Lab Ltd Improvements in or relating to cephalosporin derivatives
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
ZA72568B (en) * 1971-01-29 1972-10-25 Glaxo Lab Ltd Improvements in or relating to antibiotics
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds

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FR2137899B1 (en) 1976-08-20
NL166688B (en) 1981-04-15
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CS245754B2 (en) 1986-10-16
IL39429A (en) 1978-04-30
IE38172B1 (en) 1978-01-18
CH591497A5 (en) 1977-09-30
JPS531280B1 (en) 1978-01-17
JPS6324993B2 (en) 1988-05-23
DE2223375A1 (en) 1972-11-23
DK155187B (en) 1989-02-27
YU126772A (en) 1982-02-28
CS245753B2 (en) 1986-10-16
NL166688C (en) 1985-01-16
ES430104A1 (en) 1976-10-01
GB1399086A (en) 1975-06-25
KE2895A (en) 1978-11-10
CA1027554A (en) 1978-03-07
JPS54135792A (en) 1979-10-22
FR2137900A1 (en) 1972-12-29
IL39429A0 (en) 1972-07-26
JPS5328141A (en) 1978-03-16
YU321379A (en) 1982-02-28
FR2137899A1 (en) 1972-12-29
HK66078A (en) 1978-11-24
FR2137900B1 (en) 1976-04-16
AT336786B (en) 1977-05-25
ATA420872A (en) 1976-09-15
CY971A (en) 1978-12-22
ES402651A1 (en) 1975-11-01
DK155187C (en) 1989-07-17
SE457795B (en) 1989-01-30
DE2223375C2 (en) 1985-05-15
YU41807B (en) 1988-02-29
MY7800466A (en) 1978-12-31
DE2265234C2 (en) 1983-02-10
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IE38172L (en) 1972-11-14
NO154797C (en) 1986-12-29

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