NO133649B - - Google Patents
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- Publication number
- NO133649B NO133649B NO944/71A NO94471A NO133649B NO 133649 B NO133649 B NO 133649B NO 944/71 A NO944/71 A NO 944/71A NO 94471 A NO94471 A NO 94471A NO 133649 B NO133649 B NO 133649B
- Authority
- NO
- Norway
- Prior art keywords
- colloidal
- core
- complex
- capsule
- capsules
- Prior art date
Links
- 239000002775 capsule Substances 0.000 claims description 112
- 239000000463 material Substances 0.000 claims description 98
- 239000011162 core material Substances 0.000 claims description 57
- 239000007788 liquid Substances 0.000 claims description 45
- 238000000034 method Methods 0.000 claims description 34
- 230000008021 deposition Effects 0.000 claims description 33
- 239000007787 solid Substances 0.000 claims description 31
- 239000012736 aqueous medium Substances 0.000 claims description 21
- 238000005354 coacervation Methods 0.000 claims description 21
- 239000006185 dispersion Substances 0.000 claims description 18
- 239000007864 aqueous solution Substances 0.000 claims description 17
- 239000000243 solution Substances 0.000 claims description 17
- 239000000126 substance Substances 0.000 claims description 16
- 238000003756 stirring Methods 0.000 claims description 10
- 239000002609 medium Substances 0.000 claims description 5
- 230000015572 biosynthetic process Effects 0.000 claims description 4
- 230000015556 catabolic process Effects 0.000 claims description 4
- 238000001816 cooling Methods 0.000 claims description 3
- 238000004132 cross linking Methods 0.000 claims description 3
- 238000012546 transfer Methods 0.000 claims description 3
- 239000000084 colloidal system Substances 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 claims description 2
- 239000013589 supplement Substances 0.000 claims description 2
- 239000000725 suspension Substances 0.000 claims 3
- 238000001246 colloidal dispersion Methods 0.000 claims 1
- DIOQZVSQGTUSAI-UHFFFAOYSA-N decane Chemical compound CCCCCCCCCC DIOQZVSQGTUSAI-UHFFFAOYSA-N 0.000 description 14
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 12
- -1 polyethylene maleic anhydride copolymer Polymers 0.000 description 10
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 9
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
- 239000000203 mixture Substances 0.000 description 8
- 108010010803 Gelatin Proteins 0.000 description 7
- 229920000159 gelatin Polymers 0.000 description 7
- 239000008273 gelatin Substances 0.000 description 7
- 235000019322 gelatine Nutrition 0.000 description 7
- 235000011852 gelatine desserts Nutrition 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 7
- 239000003921 oil Substances 0.000 description 7
- 235000019198 oils Nutrition 0.000 description 7
- 239000002245 particle Substances 0.000 description 6
- 230000035508 accumulation Effects 0.000 description 5
- 238000009825 accumulation Methods 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 4
- 244000215068 Acacia senegal Species 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- 229920000084 Gum arabic Polymers 0.000 description 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- 235000010489 acacia gum Nutrition 0.000 description 3
- 239000000205 acacia gum Substances 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 2
- 239000010775 animal oil Substances 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 239000000975 dye Substances 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000003350 kerosene Substances 0.000 description 2
- 239000000696 magnetic material Substances 0.000 description 2
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 2
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 230000004942 nuclear accumulation Effects 0.000 description 2
- 239000011236 particulate material Substances 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- WWMIMRADNBGDHP-UHFFFAOYSA-N 2-hydroxyhexanedial Chemical compound O=CC(O)CCCC=O WWMIMRADNBGDHP-UHFFFAOYSA-N 0.000 description 1
- 235000019501 Lemon oil Nutrition 0.000 description 1
- 241000779819 Syncarpia glomulifera Species 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 125000006267 biphenyl group Chemical group 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- 239000003431 cross linking reagent Substances 0.000 description 1
- 239000002612 dispersion medium Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229940013317 fish oils Drugs 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 239000000446 fuel Substances 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 239000002198 insoluble material Substances 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 239000010699 lard oil Substances 0.000 description 1
- 239000010501 lemon oil Substances 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 239000006193 liquid solution Substances 0.000 description 1
- 229960001047 methyl salicylate Drugs 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000001739 pinus spp. Substances 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 239000004071 soot Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 229940036248 turpentine Drugs 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1234870 | 1970-03-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO133649B true NO133649B (en, 2012) | 1976-03-01 |
| NO133649C NO133649C (en, 2012) | 1976-06-09 |
Family
ID=10002863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO944/71A NO133649C (en, 2012) | 1970-03-13 | 1971-03-12 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4031214A (en, 2012) |
| JP (1) | JPS5317647B1 (en, 2012) |
| AT (1) | AT304147B (en, 2012) |
| BE (1) | BE764216A (en, 2012) |
| CA (1) | CA940450A (en, 2012) |
| DK (1) | DK128229B (en, 2012) |
| ES (1) | ES389164A1 (en, 2012) |
| FI (1) | FI50766C (en, 2012) |
| FR (1) | FR2085703B1 (en, 2012) |
| GB (1) | GB1347472A (en, 2012) |
| IE (1) | IE35013B1 (en, 2012) |
| IL (1) | IL36409A (en, 2012) |
| IT (1) | IT1011004B (en, 2012) |
| KE (1) | KE2738A (en, 2012) |
| NL (1) | NL168704C (en, 2012) |
| NO (1) | NO133649C (en, 2012) |
| SE (1) | SE386823B (en, 2012) |
| ZA (1) | ZA711632B (en, 2012) |
| ZM (1) | ZM3271A1 (en, 2012) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK136934B (da) * | 1976-02-06 | 1977-12-19 | Rosco As | Fremgangsmåde til fremstilling af en klar, stabil, injicerbar opløsning indeholdende et sulfonamid og en potentiator. |
| EP0007591B1 (de) * | 1978-08-01 | 1982-07-28 | Ciba-Geigy Ag | Stabile flüssige Arzneimittelformulierung auf Basis von 2,6-Diamino-5-(3',4',5'-trimethoxybenzyl)-pyrimidin(Trimethoprim) und einem Sulfonamid, Verfahren zu ihrer Herstellung und ihre Verwendung |
| AR220263A1 (es) * | 1980-02-19 | 1980-10-15 | Bago Lab Sa | Procedimiento para obtener una preparacion inyectable de sulfonamida potenciada de baja irritabilidad |
| GB2112381B (en) * | 1981-09-30 | 1986-08-28 | Nat Res Dev | Cyclic ether and thioether derivatives for use as diluents in sustained release compositions |
| US5335675A (en) * | 1988-11-15 | 1994-08-09 | Family Health International | Stress-softened elastomeric films, articles, and method and apparatus for making such films and articles |
| US5135924A (en) * | 1989-01-03 | 1992-08-04 | Hoffmann-La Roche Inc. | Therapeutic treatment of animals with oral administration of ormetoprim-potentiated sulfonamides |
| US6211185B1 (en) | 1999-05-05 | 2001-04-03 | Veterinary Pharmacy Corporation | Concentrate comprising a sulfonamide in solution, a 2,4-diaminopyrimidine in stable suspension within said solution, and a suspending agent |
| US20060205682A1 (en) * | 2005-02-25 | 2006-09-14 | Roberts Richard H | Antibiotic and combinations of antibiotic and symptomatic relief agent formulations |
| CN113712914A (zh) * | 2021-10-18 | 2021-11-30 | 杭州艾贝德生命科技研究院有限公司 | 一种复方磺胺嘧啶混悬液的制备方法 |
| CN113952296B (zh) * | 2021-11-15 | 2023-10-13 | 山东新华制药股份有限公司 | 一种复方磺胺甲噁唑注射液的制备方法 |
| CN118304259B (zh) * | 2024-04-10 | 2024-12-10 | 南京康川济医药科技有限公司 | 一种复方磺胺甲噁唑注射液及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH544053A (de) * | 1966-05-09 | 1973-11-15 | Hoffmann La Roche | Verfahren zur Herstellung von Sulfonamidderivaten |
| US3728452A (en) * | 1971-01-20 | 1973-04-17 | Abic Ltd | Water-soluble composition comprising sulfadimidine and pyrimethamine |
-
1971
- 1971-03-11 ZM ZM32/71A patent/ZM3271A1/xx unknown
- 1971-03-12 AT AT215271A patent/AT304147B/de not_active IP Right Cessation
- 1971-03-12 IT IT49010/71A patent/IT1011004B/it active
- 1971-03-12 SE SE7103189A patent/SE386823B/xx unknown
- 1971-03-12 BE BE764216A patent/BE764216A/xx not_active IP Right Cessation
- 1971-03-12 DK DK119271AA patent/DK128229B/da not_active IP Right Cessation
- 1971-03-12 FI FI710727A patent/FI50766C/fi active
- 1971-03-12 IE IE317/71A patent/IE35013B1/xx unknown
- 1971-03-12 NO NO944/71A patent/NO133649C/no unknown
- 1971-03-12 IL IL36409A patent/IL36409A/xx unknown
- 1971-03-12 CA CA107,656A patent/CA940450A/en not_active Expired
- 1971-03-12 FR FR7108681A patent/FR2085703B1/fr not_active Expired
- 1971-03-12 NL NLAANVRAGE7103335,A patent/NL168704C/xx not_active IP Right Cessation
- 1971-03-12 ZA ZA711632A patent/ZA711632B/xx unknown
- 1971-03-12 ES ES389164A patent/ES389164A1/es not_active Expired
- 1971-03-13 JP JP1403571A patent/JPS5317647B1/ja active Pending
- 1971-05-27 GB GB1234870A patent/GB1347472A/en not_active Expired
-
1975
- 1975-04-07 US US05/565,964 patent/US4031214A/en not_active Expired - Lifetime
-
1977
- 1977-05-28 KE KE2738A patent/KE2738A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL36409A (en) | 1974-01-14 |
| SE386823B (sv) | 1976-08-23 |
| NO133649C (en, 2012) | 1976-06-09 |
| FR2085703B1 (en, 2012) | 1974-05-31 |
| FI50766C (fi) | 1976-07-12 |
| IT1011004B (it) | 1977-01-20 |
| FR2085703A1 (en, 2012) | 1971-12-31 |
| GB1347472A (en) | 1974-02-27 |
| IL36409A0 (en) | 1971-05-26 |
| DK128229B (da) | 1974-03-25 |
| ES389164A1 (es) | 1974-09-01 |
| ZM3271A1 (en) | 1972-10-23 |
| BE764216A (fr) | 1971-09-13 |
| NL168704C (nl) | 1982-05-17 |
| JPS5317647B1 (en, 2012) | 1978-06-09 |
| NL7103335A (en, 2012) | 1971-09-15 |
| US4031214A (en) | 1977-06-21 |
| AT304147B (de) | 1972-12-27 |
| NL168704B (nl) | 1981-12-16 |
| CA940450A (en) | 1974-01-22 |
| FI50766B (en, 2012) | 1976-03-31 |
| IE35013L (en) | 1971-09-13 |
| DE2112049A1 (de) | 1971-09-23 |
| IE35013B1 (en) | 1975-10-15 |
| KE2738A (en) | 1977-06-10 |
| ZA711632B (en) | 1972-10-25 |
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