NO132851B - - Google Patents
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- Publication number
- NO132851B NO132851B NO3832/69A NO383269A NO132851B NO 132851 B NO132851 B NO 132851B NO 3832/69 A NO3832/69 A NO 3832/69A NO 383269 A NO383269 A NO 383269A NO 132851 B NO132851 B NO 132851B
- Authority
- NO
- Norway
- Prior art keywords
- accordance
- blood
- ratio
- electrodes
- electrical
- Prior art date
Links
- 210000004369 blood Anatomy 0.000 claims description 51
- 239000008280 blood Substances 0.000 claims description 51
- 238000000034 method Methods 0.000 claims description 40
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- 238000005345 coagulation Methods 0.000 claims description 25
- 239000000523 sample Substances 0.000 claims description 22
- 230000000694 effects Effects 0.000 claims description 21
- 238000003860 storage Methods 0.000 claims description 19
- 238000012544 monitoring process Methods 0.000 claims description 17
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- 238000012360 testing method Methods 0.000 claims description 14
- 239000011521 glass Substances 0.000 claims description 13
- 230000023555 blood coagulation Effects 0.000 claims description 12
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 12
- 239000000463 material Substances 0.000 claims description 7
- 239000003990 capacitor Substances 0.000 claims description 6
- 239000013068 control sample Substances 0.000 claims description 6
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- 238000011161 development Methods 0.000 claims description 6
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- 230000003851 biochemical process Effects 0.000 claims description 4
- 230000031018 biological processes and functions Effects 0.000 claims description 4
- 238000012986 modification Methods 0.000 claims description 4
- 230000004048 modification Effects 0.000 claims description 4
- 239000000126 substance Substances 0.000 claims description 4
- 238000009966 trimming Methods 0.000 claims description 4
- 229910001020 Au alloy Inorganic materials 0.000 claims description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 3
- 229910001260 Pt alloy Inorganic materials 0.000 claims description 3
- 229910002804 graphite Inorganic materials 0.000 claims description 3
- 239000010439 graphite Substances 0.000 claims description 3
- 239000004020 conductor Substances 0.000 claims 6
- 229920001296 polysiloxane Polymers 0.000 claims 3
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- 239000003353 gold alloy Substances 0.000 claims 1
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- 210000004027 cell Anatomy 0.000 description 69
- 206010053567 Coagulopathies Diseases 0.000 description 8
- 230000035602 clotting Effects 0.000 description 8
- 210000002381 plasma Anatomy 0.000 description 8
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 7
- 229960002897 heparin Drugs 0.000 description 7
- 229920000669 heparin Polymers 0.000 description 7
- 238000006243 chemical reaction Methods 0.000 description 6
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- 108010094028 Prothrombin Proteins 0.000 description 5
- 102100027378 Prothrombin Human genes 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 239000003814 drug Substances 0.000 description 5
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 5
- 239000010931 gold Substances 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 229910052697 platinum Inorganic materials 0.000 description 5
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- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 3
- 239000003242 anti bacterial agent Substances 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
- 229940127219 anticoagulant drug Drugs 0.000 description 3
- DMFGNRRURHSENX-UHFFFAOYSA-N beryllium copper Chemical compound [Be].[Cu] DMFGNRRURHSENX-UHFFFAOYSA-N 0.000 description 3
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- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
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- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 2
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- PGOHTUIFYSHAQG-LJSDBVFPSA-N (2S)-6-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoyl]amino]hexanoic acid Chemical compound CSCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(O)=O PGOHTUIFYSHAQG-LJSDBVFPSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 201000009030 Carcinoma Diseases 0.000 description 1
- 206010011091 Coronary artery thrombosis Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
- 208000006193 Pulmonary infarction Diseases 0.000 description 1
- 108010000499 Thromboplastin Proteins 0.000 description 1
- 102000002262 Thromboplastin Human genes 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
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- 230000003115 biocidal effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
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- 208000002528 coronary thrombosis Diseases 0.000 description 1
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- 210000003743 erythrocyte Anatomy 0.000 description 1
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- 238000001990 intravenous administration Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000006193 liquid solution Substances 0.000 description 1
- 239000006194 liquid suspension Substances 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
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- 229910000679 solder Inorganic materials 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000009424 thromboembolic effect Effects 0.000 description 1
- 201000005060 thrombophlebitis Diseases 0.000 description 1
- 230000001732 thrombotic effect Effects 0.000 description 1
- 231100000732 tissue residue Toxicity 0.000 description 1
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- 229960001005 tuberculin Drugs 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
- G01N27/06—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
- G01N27/06—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
- G01N27/07—Construction of measuring vessels; Electrodes therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Electrochemistry (AREA)
- Ecology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB36850/69A GB1299363A (en) | 1968-09-27 | 1968-09-27 | Monitoring of chemical, bio-chemical and biological reactions, particularly blood-clotting |
GB4614168 | 1968-09-27 | ||
GB4677168 | 1968-10-02 | ||
GB4754068 | 1968-10-07 | ||
GB5155268 | 1968-10-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
NO132851B true NO132851B (xx) | 1975-10-06 |
NO132851C NO132851C (xx) | 1976-01-14 |
Family
ID=27516334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO3832/69A NO132851C (xx) | 1968-09-27 | 1969-09-26 |
Country Status (12)
Country | Link |
---|---|
US (1) | US3699437A (xx) |
AT (1) | AT320864B (xx) |
BE (1) | BE739401A (xx) |
CH (1) | CH517942A (xx) |
FR (1) | FR2019062A1 (xx) |
GB (1) | GB1299363A (xx) |
IE (1) | IE33584B1 (xx) |
IL (1) | IL33080A (xx) |
IT (1) | IT942031B (xx) |
NL (1) | NL6914627A (xx) |
NO (1) | NO132851C (xx) |
SE (1) | SE379860B (xx) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3772591A (en) * | 1972-04-12 | 1973-11-13 | Fisher Scientific Co | Method and apparatus for analyzing blood properties |
JPS5651758B2 (xx) * | 1973-04-25 | 1981-12-08 | ||
GB1585067A (en) * | 1976-10-19 | 1981-02-25 | Nat Res Dev | Detection of bacterial activity |
DE2966583D1 (en) * | 1978-10-02 | 1984-03-01 | Wellcome Found | A method of and apparatus for monitoring platelet aggregation and test cell for use in such method and apparatus |
US4301414A (en) * | 1979-10-29 | 1981-11-17 | United States Surgical Corporation | Disposable sample card and method of making same |
DE3175570D1 (en) * | 1980-03-08 | 1986-12-11 | Japan Tectron Instr Corp | Methods of monitoring micro-organisms and media for culture |
DE3337618A1 (de) * | 1983-10-15 | 1985-04-25 | Heinz Prof. Dr. 4400 Münster Schröer | Anordnung zur messung der ex-vivo-blutungszeit |
GB8621757D0 (en) * | 1986-09-10 | 1986-10-15 | Gorog P | Blood testing device |
US5174961A (en) * | 1991-01-18 | 1992-12-29 | Hemotec, Inc. | High sensitivity coagulation detection apparatus |
US5314826A (en) * | 1991-08-23 | 1994-05-24 | Medtronic Hemotec, Inc. | Platelet activation and function evaluation technique |
US5316730A (en) * | 1992-12-07 | 1994-05-31 | Xylum Corporation | Disposable cartridge for investigating physical properties of blood |
US5522255A (en) * | 1993-08-31 | 1996-06-04 | Boehringer Mannheim Corporation | Fluid dose, flow and coagulation sensor for medical instrument |
US5526111A (en) * | 1993-08-31 | 1996-06-11 | Boehringer Mannheim Corporation | Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control |
US5731212A (en) * | 1994-12-20 | 1998-03-24 | International Technidyne Corporation | Test apparatus and method for testing cuvette accommodated samples |
US5925319A (en) * | 1996-04-30 | 1999-07-20 | Medtronic, Inc. | Test cartridge for evaluating blood platelet functionality |
US6004819A (en) * | 1996-11-04 | 1999-12-21 | Xylum Corporation | Blood testing device |
WO1998039643A1 (en) * | 1997-03-05 | 1998-09-11 | Diametrics | Method and apparatus for measurement of whole blood coagulation parameters |
US6046051A (en) * | 1997-06-27 | 2000-04-04 | Hemosense, Inc. | Method and device for measuring blood coagulation or lysis by viscosity changes |
US7021122B1 (en) * | 1998-03-19 | 2006-04-04 | Orgenics Biosensors Ltd. | Device for the determination of blood clotting by capacitance or resistance |
DE69942146D1 (de) * | 1998-03-19 | 2010-04-29 | Inverness Medical Switzerland | GERÄT ZUR BESTIMMUNG DER BLUT-KOAGULATION mittels Widerstandsmessungen |
US7144495B2 (en) | 2000-12-13 | 2006-12-05 | Lifescan, Inc. | Electrochemical test strip with an integrated micro-needle and associated methods |
US6620310B1 (en) * | 2000-12-13 | 2003-09-16 | Lifescan, Inc. | Electrochemical coagulation assay and device |
GB0030929D0 (en) * | 2000-12-19 | 2001-01-31 | Inverness Medical Ltd | Analyte measurement |
GB2392724A (en) * | 2002-09-06 | 2004-03-10 | Ian Stoakes | Methods of and apparatus for blood analysis |
US7291310B2 (en) * | 2002-12-17 | 2007-11-06 | The Regents Of The University Of Michigan | Microsystem for determining clotting time of blood and low-cost, single-use device for use therein |
ES2340378T3 (es) * | 2003-12-16 | 2010-06-02 | Dynabyte Informationssysteme Gmbh | Dispositivo de cartucho para el analisis de sangre. |
ATE532058T1 (de) * | 2004-05-17 | 2011-11-15 | Medtronic Inc | Point-of-care-heparinbestimmungssystem |
US7837941B2 (en) | 2006-04-07 | 2010-11-23 | Agamatrix, Inc. | Method and apparatus for monitoring alteration of flow characteristics in a liquid sample |
US7674616B2 (en) * | 2006-09-14 | 2010-03-09 | Hemosense, Inc. | Device and method for measuring properties of a sample |
US20080297169A1 (en) * | 2007-05-31 | 2008-12-04 | Greenquist Alfred C | Particle Fraction Determination of A Sample |
EP2201136B1 (en) | 2007-10-01 | 2017-12-06 | Nabsys 2.0 LLC | Nanopore sequencing by hybridization of probes to form ternary complexes and variable range alignment |
US9650668B2 (en) | 2008-09-03 | 2017-05-16 | Nabsys 2.0 Llc | Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels |
US8262879B2 (en) | 2008-09-03 | 2012-09-11 | Nabsys, Inc. | Devices and methods for determining the length of biopolymers and distances between probes bound thereto |
EP2342362B1 (en) | 2008-09-03 | 2017-03-01 | Nabsys 2.0 LLC | Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels |
DE102008050092A1 (de) * | 2008-10-06 | 2010-04-08 | Hach Lange Gmbh | Mobile Wasser-Analyseanordnung |
US8455260B2 (en) | 2009-03-27 | 2013-06-04 | Massachusetts Institute Of Technology | Tagged-fragment map assembly |
EP2395353B1 (en) | 2010-06-09 | 2018-08-22 | Apex Biotechnology Corp. | Device and method for measuring prothrombin time and hematocrit by analyzing change in reactance in a sample |
US8715933B2 (en) | 2010-09-27 | 2014-05-06 | Nabsys, Inc. | Assay methods using nicking endonucleases |
WO2012067911A1 (en) | 2010-11-16 | 2012-05-24 | Nabsys, Inc. | Methods for sequencing a biomolecule by detecting relative positions of hybridized probes |
WO2012109574A2 (en) | 2011-02-11 | 2012-08-16 | Nabsys, Inc. | Assay methods using dna binding proteins |
US9914966B1 (en) | 2012-12-20 | 2018-03-13 | Nabsys 2.0 Llc | Apparatus and methods for analysis of biomolecules using high frequency alternating current excitation |
US10294516B2 (en) | 2013-01-18 | 2019-05-21 | Nabsys 2.0 Llc | Enhanced probe binding |
US20150140671A1 (en) * | 2013-11-18 | 2015-05-21 | Johnson Electric S.A. | Method and system for assembling a microfluidic sensor |
JP2016061731A (ja) * | 2014-09-19 | 2016-04-25 | ソニー株式会社 | 電気的特性測定装置及びプログラム |
CN107107056B (zh) | 2014-09-26 | 2020-04-14 | 雅培医护站股份有限公司 | 用于流体样本中的凝结测定的单通道盒设备 |
US10473612B2 (en) * | 2014-09-26 | 2019-11-12 | Abbott Point Of Care Inc. | Cartridge device identification for coagulation assays in fluid samples |
WO2016049533A1 (en) | 2014-09-26 | 2016-03-31 | Abbott Point Of Care Inc. | Cartridge device with fluidic junctions for coagulation assays in fluid samples |
EP3198280B1 (en) | 2014-09-26 | 2021-05-26 | Abbott Point Of Care, Inc. | Sensors for assaying coagulation in fluid samples |
CN107110875A (zh) | 2014-09-26 | 2017-08-29 | 雅培医护站股份有限公司 | 用在凝固测定中的鞣花酸制剂 |
US10247741B2 (en) | 2014-09-26 | 2019-04-02 | Abbott Point Of Care Inc. | Microfabricated device with micro-environment sensors for assaying coagulation in fluid samples |
FR3043780B1 (fr) * | 2015-11-16 | 2017-12-15 | Hospices Civils Lyon | Methode de diagnostic d'anomalies de la coagulation sanguine |
CN108318560B (zh) * | 2018-01-19 | 2021-06-04 | 国力天(深圳)科技有限公司 | 一种便携式微电极法血液检测仪及其检测方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2555937A (en) * | 1949-08-25 | 1951-06-05 | Robert L Rosenthal | Method and apparatus for measuring resistance of blood during clotting |
GB707914A (en) * | 1951-08-28 | 1954-04-28 | Ass Portland Cement | Method and apparatus for measuring the oxygen content in gaseous mixtures |
GB781058A (en) * | 1952-05-23 | 1957-08-14 | Elliott Brothers London Ltd | Improvements in the continuous measurement and recording of the conductivity of electrolytic solutions |
US3524727A (en) * | 1965-06-16 | 1970-08-18 | Corning Glass Works | Method and device for determining serological data by an agglomeration test |
US3374672A (en) * | 1965-07-06 | 1968-03-26 | California Inst Res Found | Flowmeter |
US3467862A (en) * | 1967-02-20 | 1969-09-16 | Usher Abramovich Vatmakher | Apparatus for recording resistance changes during the entire coagulation process in a biological fluid |
-
1968
- 1968-09-27 GB GB36850/69A patent/GB1299363A/en not_active Expired
-
1969
- 1969-08-21 US US863411A patent/US3699437A/en not_active Expired - Lifetime
- 1969-09-25 AT AT908769A patent/AT320864B/de not_active IP Right Cessation
- 1969-09-25 BE BE739401D patent/BE739401A/xx unknown
- 1969-09-26 CH CH1459669A patent/CH517942A/de not_active IP Right Cessation
- 1969-09-26 SE SE6913270A patent/SE379860B/xx unknown
- 1969-09-26 FR FR6932941A patent/FR2019062A1/fr not_active Withdrawn
- 1969-09-26 NL NL6914627A patent/NL6914627A/xx unknown
- 1969-09-26 NO NO3832/69A patent/NO132851C/no unknown
- 1969-09-27 IT IT22600/69A patent/IT942031B/it active
- 1969-09-28 IL IL6933080A patent/IL33080A/xx unknown
- 1969-09-29 IE IE1348/69A patent/IE33584B1/xx unknown
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IL33080A (en) | 1973-06-29 |
IT942031B (it) | 1973-03-20 |
DE1947051A1 (de) | 1970-06-11 |
GB1299363A (en) | 1972-12-13 |
DE1947051B2 (de) | 1976-06-24 |
CH517942A (de) | 1972-01-15 |
IE33584L (en) | 1970-03-27 |
AT320864B (de) | 1975-03-10 |
US3699437A (en) | 1972-10-17 |
NL6914627A (xx) | 1970-04-01 |
FR2019062A1 (xx) | 1970-06-26 |
IL33080A0 (en) | 1970-02-19 |
BE739401A (xx) | 1970-03-02 |
NO132851C (xx) | 1976-01-14 |
IE33584B1 (en) | 1974-08-21 |
SE379860B (xx) | 1975-10-20 |
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