NO122031B - - Google Patents
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- Publication number
- NO122031B NO122031B NO164282A NO16428266A NO122031B NO 122031 B NO122031 B NO 122031B NO 164282 A NO164282 A NO 164282A NO 16428266 A NO16428266 A NO 16428266A NO 122031 B NO122031 B NO 122031B
- Authority
- NO
- Norway
- Prior art keywords
- virus
- chicken
- mumps
- fetal
- cultures
- Prior art date
Links
- 241000700605 Viruses Species 0.000 claims description 23
- 241000287828 Gallus gallus Species 0.000 claims description 16
- 241000711386 Mumps virus Species 0.000 claims description 14
- 229960005486 vaccine Drugs 0.000 claims description 10
- 235000013601 eggs Nutrition 0.000 claims description 9
- 210000003754 fetus Anatomy 0.000 claims description 9
- 230000001605 fetal effect Effects 0.000 claims description 8
- 238000004519 manufacturing process Methods 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 5
- 239000002609 medium Substances 0.000 description 8
- 208000005647 Mumps Diseases 0.000 description 7
- 210000003837 chick embryo Anatomy 0.000 description 6
- 208000010805 mumps infectious disease Diseases 0.000 description 6
- 210000001519 tissue Anatomy 0.000 description 6
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 230000002238 attenuated effect Effects 0.000 description 4
- 239000001963 growth medium Substances 0.000 description 4
- 238000002955 isolation Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 210000002966 serum Anatomy 0.000 description 4
- 239000003381 stabilizer Substances 0.000 description 4
- 238000004448 titration Methods 0.000 description 4
- 230000006978 adaptation Effects 0.000 description 3
- 244000309466 calf Species 0.000 description 3
- 210000000991 chicken egg Anatomy 0.000 description 3
- 238000011534 incubation Methods 0.000 description 3
- 210000004789 organ system Anatomy 0.000 description 3
- 241000282693 Cercopithecidae Species 0.000 description 2
- 201000005505 Measles Diseases 0.000 description 2
- 229930193140 Neomycin Natural products 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 102000004142 Trypsin Human genes 0.000 description 2
- 108090000631 Trypsin Proteins 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 238000003306 harvesting Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 229940095293 mumps vaccine Drugs 0.000 description 2
- 229960004927 neomycin Drugs 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 229960001322 trypsin Drugs 0.000 description 2
- 239000012588 trypsin Substances 0.000 description 2
- 208000006740 Aseptic Meningitis Diseases 0.000 description 1
- 206010003694 Atrophy Diseases 0.000 description 1
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 102000008100 Human Serum Albumin Human genes 0.000 description 1
- 108091006905 Human Serum Albumin Proteins 0.000 description 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 description 1
- 206010027201 Meningitis aseptic Diseases 0.000 description 1
- 206010029240 Neuritis Diseases 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 206010033645 Pancreatitis Diseases 0.000 description 1
- 241000283984 Rodentia Species 0.000 description 1
- 206010039705 Scleritis Diseases 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 206010058874 Viraemia Diseases 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 235000011089 carbon dioxide Nutrition 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 239000012568 clinical material Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 210000003027 ear inner Anatomy 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 206010014599 encephalitis Diseases 0.000 description 1
- 201000002491 encephalomyelitis Diseases 0.000 description 1
- 210000000918 epididymis Anatomy 0.000 description 1
- 201000010063 epididymitis Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000001508 eye Anatomy 0.000 description 1
- 210000000256 facial nerve Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 210000005075 mammary gland Anatomy 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 210000001328 optic nerve Anatomy 0.000 description 1
- 201000005737 orchitis Diseases 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 210000005084 renal tissue Anatomy 0.000 description 1
- 210000003079 salivary gland Anatomy 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 210000003670 sublingual gland Anatomy 0.000 description 1
- 210000001913 submandibular gland Anatomy 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A61K39/165—Mumps or measles virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
- C12N2760/18734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47965365A | 1965-08-13 | 1965-08-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO122031B true NO122031B (ja) | 1971-05-10 |
Family
ID=23904868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO164282A NO122031B (ja) | 1965-08-13 | 1966-08-12 |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5238089B1 (ja) |
| BE (1) | BE685270A (ja) |
| BR (1) | BR6681974D0 (ja) |
| CH (1) | CH475355A (ja) |
| CS (1) | CS161688B2 (ja) |
| CY (1) | CY536A (ja) |
| DE (1) | DE1617621B1 (ja) |
| DK (1) | DK116677B (ja) |
| ES (1) | ES330274A1 (ja) |
| FI (1) | FI43094B (ja) |
| FR (2) | FR1509944A (ja) |
| GB (1) | GB1140766A (ja) |
| IL (1) | IL26244A (ja) |
| NO (1) | NO122031B (ja) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2076787A5 (en) * | 1970-01-28 | 1971-10-15 | Merieux Inst | Lyophilisation stabiliser - for viruses contg potassium phosphate lactose and albumin |
-
1965
- 1965-08-01 IL IL26244A patent/IL26244A/xx unknown
-
1966
- 1966-07-19 CS CS4877A patent/CS161688B2/cs unknown
- 1966-08-03 GB GB34791/66A patent/GB1140766A/en not_active Expired
- 1966-08-04 ES ES0330274A patent/ES330274A1/es not_active Expired
- 1966-08-08 CH CH1137766A patent/CH475355A/de not_active IP Right Cessation
- 1966-08-09 BE BE685270D patent/BE685270A/xx not_active IP Right Cessation
- 1966-08-09 BR BR181974/66A patent/BR6681974D0/pt unknown
- 1966-08-10 DE DE1966M0070534 patent/DE1617621B1/de active Pending
- 1966-08-11 FI FI2099/66A patent/FI43094B/fi active
- 1966-08-12 FR FR73061A patent/FR1509944A/fr not_active Expired
- 1966-08-12 DK DK414266AA patent/DK116677B/da unknown
- 1966-08-12 FR FR72964A patent/FR5807M/fr not_active Expired
- 1966-08-12 JP JP41052676A patent/JPS5238089B1/ja active Pending
- 1966-08-12 NO NO164282A patent/NO122031B/no unknown
-
1970
- 1970-04-10 CY CY53670A patent/CY536A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1140766A (en) | 1969-01-22 |
| BE685270A (ja) | 1967-02-09 |
| FI43094B (ja) | 1970-10-01 |
| ES330274A1 (es) | 1967-06-16 |
| IL26244A (en) | 1970-03-22 |
| JPS5238089B1 (ja) | 1977-09-27 |
| FR5807M (ja) | 1968-02-19 |
| BR6681974D0 (pt) | 1973-12-26 |
| CS161688B2 (ja) | 1975-06-10 |
| DE1617621B1 (de) | 1971-03-04 |
| DK116677B (da) | 1970-02-02 |
| FR1509944A (fr) | 1968-01-19 |
| CH475355A (de) | 1969-07-15 |
| CY536A (en) | 1970-04-10 |
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