GB1140766A - Vaccine and its preparation - Google Patents
Vaccine and its preparationInfo
- Publication number
- GB1140766A GB1140766A GB34791/66A GB3479166A GB1140766A GB 1140766 A GB1140766 A GB 1140766A GB 34791/66 A GB34791/66 A GB 34791/66A GB 3479166 A GB3479166 A GB 3479166A GB 1140766 A GB1140766 A GB 1140766A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vaccine
- chick embryo
- virus
- aug
- virulent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A61K39/165—Mumps or measles virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
- C12N2760/18734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
1,140,766. Mumps vaccine. MERCK & CO. Inc. 3 Aug., 1966 [13 Aug., 1965], No. 34798/66. Heading A5B. Mumps vaccine is prepared by attenuating a live virulent mump virus by growing it in at least ten successive passages in embryonated hens eggs and then propagating it in chick embryo tissue culture containing tissue of 9-11 day old chick embryo, at 30-38‹C. Preferably at least ten chick embryo tissue passages are made. The virulent virus may be derived from clinical material, isolated in a suitable cell culture and adapted to chick embryo tissue culture. The virus containing fluids are harvested, preferably stabilised with e.g. sucrose, human albumin, glutamine, phosphate or mixtures thereof, and then stored frozen for subsequent use as a vaccine, or filled into ampules, and freeze-dried for reconstitution with sterile water to provide a vaccine.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47965365A | 1965-08-13 | 1965-08-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1140766A true GB1140766A (en) | 1969-01-22 |
Family
ID=23904868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB34791/66A Expired GB1140766A (en) | 1965-08-13 | 1966-08-03 | Vaccine and its preparation |
Country Status (14)
Country | Link |
---|---|
JP (1) | JPS5238089B1 (en) |
BE (1) | BE685270A (en) |
BR (1) | BR6681974D0 (en) |
CH (1) | CH475355A (en) |
CS (1) | CS161688B2 (en) |
CY (1) | CY536A (en) |
DE (1) | DE1617621B1 (en) |
DK (1) | DK116677B (en) |
ES (1) | ES330274A1 (en) |
FI (1) | FI43094B (en) |
FR (2) | FR5807M (en) |
GB (1) | GB1140766A (en) |
IL (1) | IL26244A (en) |
NO (1) | NO122031B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2076787A5 (en) * | 1970-01-28 | 1971-10-15 | Merieux Inst | Lyophilisation stabiliser - for viruses contg potassium phosphate lactose and albumin |
-
1965
- 1965-08-01 IL IL26244A patent/IL26244A/en unknown
-
1966
- 1966-07-19 CS CS4877A patent/CS161688B2/cs unknown
- 1966-08-03 GB GB34791/66A patent/GB1140766A/en not_active Expired
- 1966-08-04 ES ES0330274A patent/ES330274A1/en not_active Expired
- 1966-08-08 CH CH1137766A patent/CH475355A/en not_active IP Right Cessation
- 1966-08-09 BR BR181974/66A patent/BR6681974D0/en unknown
- 1966-08-09 BE BE685270D patent/BE685270A/xx not_active IP Right Cessation
- 1966-08-10 DE DE1966M0070534 patent/DE1617621B1/en active Pending
- 1966-08-11 FI FI2099/66A patent/FI43094B/fi active
- 1966-08-12 NO NO164282A patent/NO122031B/no unknown
- 1966-08-12 JP JP41052676A patent/JPS5238089B1/ja active Pending
- 1966-08-12 DK DK414266AA patent/DK116677B/en unknown
- 1966-08-12 FR FR72964A patent/FR5807M/fr not_active Expired
- 1966-08-12 FR FR73061A patent/FR1509944A/en not_active Expired
-
1970
- 1970-04-10 CY CY53670A patent/CY536A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CS161688B2 (en) | 1975-06-10 |
CY536A (en) | 1970-04-10 |
DK116677B (en) | 1970-02-02 |
NO122031B (en) | 1971-05-10 |
FR5807M (en) | 1968-02-19 |
ES330274A1 (en) | 1967-06-16 |
FI43094B (en) | 1970-10-01 |
FR1509944A (en) | 1968-01-19 |
BR6681974D0 (en) | 1973-12-26 |
CH475355A (en) | 1969-07-15 |
BE685270A (en) | 1967-02-09 |
DE1617621B1 (en) | 1971-03-04 |
JPS5238089B1 (en) | 1977-09-27 |
IL26244A (en) | 1970-03-22 |
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