GB1152645A - Rubella Vaccine - Google Patents
Rubella VaccineInfo
- Publication number
- GB1152645A GB1152645A GB32603/67A GB3260367A GB1152645A GB 1152645 A GB1152645 A GB 1152645A GB 32603/67 A GB32603/67 A GB 32603/67A GB 3260367 A GB3260367 A GB 3260367A GB 1152645 A GB1152645 A GB 1152645A
- Authority
- GB
- United Kingdom
- Prior art keywords
- culture
- virus
- rubella
- rubella vaccine
- media
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/20—Rubella virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36211—Rubivirus, e.g. rubella virus
- C12N2770/36234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
1,152,645. Rubella vaccine. MERCK & CO. Inc. 14 July, 1967 [22 May, 1967], No. 32603/67. Heading A5B. A rubella vaccine is prepared by isolating rubella virus from clinical material by inoculation of chick embryo or grivet monkey tissue culture and incubating at 30-38‹C.; successively passing the virus through culture media to attenuate the virus at least one of such passages being in media comprising minced and trypsinised 9-11 day old decapitated and amputated chick embryo culture in a cell growth medium at 30-38‹C., each passage being followed by infectivity titrations on sample harvests taken at 2-14 day intervals, the harvests being frozen until tested and re-inoculated in a culture medium if too virulent. The serial passages may include incubations in grivet monkey kidney cultures, embryonated hen's eggs or duck embryo tissue cultures.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64034167A | 1967-05-22 | 1967-05-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1152645A true GB1152645A (en) | 1969-05-21 |
Family
ID=24567850
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB32603/67A Expired GB1152645A (en) | 1967-05-22 | 1967-07-14 | Rubella Vaccine |
Country Status (7)
Country | Link |
---|---|
BE (1) | BE701496A (en) |
ES (1) | ES343144A1 (en) |
FI (1) | FI43624B (en) |
FR (1) | FR1583642A (en) |
GB (1) | GB1152645A (en) |
GR (1) | GR33984B (en) |
SE (1) | SE318975B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2076787A5 (en) * | 1970-01-28 | 1971-10-15 | Merieux Inst | Lyophilisation stabiliser - for viruses contg potassium phosphate lactose and albumin |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2532548B1 (en) * | 1982-09-03 | 1985-11-08 | Pasteur Institut | NOVEL PROCESS FOR THE PRODUCTION OF VACCINES HAVING A HIGH TITLE OF VIRUSES AND HIGHLY PURIFIED VACCINES, A HIGH TITLE OF VIRUSES, SO OBTAINED |
-
1967
- 1967-07-14 SE SE10568/67A patent/SE318975B/xx unknown
- 1967-07-14 GB GB32603/67A patent/GB1152645A/en not_active Expired
- 1967-07-15 GR GR670133984A patent/GR33984B/en unknown
- 1967-07-17 ES ES343144A patent/ES343144A1/en not_active Expired
- 1967-07-18 BE BE701496D patent/BE701496A/xx unknown
- 1967-07-18 FI FI1977/67A patent/FI43624B/fi active
-
1968
- 1968-01-03 FR FR1583642D patent/FR1583642A/fr not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2076787A5 (en) * | 1970-01-28 | 1971-10-15 | Merieux Inst | Lyophilisation stabiliser - for viruses contg potassium phosphate lactose and albumin |
Also Published As
Publication number | Publication date |
---|---|
FR1583642A (en) | 1969-11-21 |
SE318975B (en) | 1969-12-22 |
GR33984B (en) | 1968-02-29 |
ES343144A1 (en) | 1968-10-01 |
FI43624B (en) | 1971-02-01 |
BE701496A (en) | 1968-01-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PLNP | Patent lapsed through nonpayment of renewal fees |