NL990021I1 - Ä7-(3-Digesubstitueerde amino)fenylÜ-pyrazoloÄ1,5-aÜpyrimidinen. - Google Patents

Ä7-(3-Digesubstitueerde amino)fenylÜ-pyrazoloÄ1,5-aÜpyrimidinen.

Info

Publication number
NL990021I1
NL990021I1 NL990021C NL990021C NL990021I1 NL 990021 I1 NL990021 I1 NL 990021I1 NL 990021 C NL990021 C NL 990021C NL 990021 C NL990021 C NL 990021C NL 990021 I1 NL990021 I1 NL 990021I1
Authority
NL
Netherlands
Prior art keywords
pyrazolo
pyrimidines
phenyl
disubstituted amino
disubstituted
Prior art date
Application number
NL990021C
Other languages
English (en)
Other versions
NL990021I2 (nl
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27055659&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL990021(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NL990021I1 publication Critical patent/NL990021I1/nl
Publication of NL990021I2 publication Critical patent/NL990021I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL990021C 1983-06-23 1999-07-22 Ä7-(3-Digesubstitueerde amino)fenylÜ-pyrazoloÄ1,5-aÜpyrimidinen. NL990021I2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50696683A 1983-06-23 1983-06-23
US06/732,986 US4626538A (en) 1983-06-23 1985-05-13 [7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines

Publications (2)

Publication Number Publication Date
NL990021I1 true NL990021I1 (nl) 1999-10-01
NL990021I2 NL990021I2 (nl) 2000-03-01

Family

ID=27055659

Family Applications (1)

Application Number Title Priority Date Filing Date
NL990021C NL990021I2 (nl) 1983-06-23 1999-07-22 Ä7-(3-Digesubstitueerde amino)fenylÜ-pyrazoloÄ1,5-aÜpyrimidinen.

Country Status (3)

Country Link
US (1) US4626538A (nl)
EP (1) EP0208846B1 (nl)
NL (1) NL990021I2 (nl)

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EP1344768B1 (en) * 1999-08-10 2005-04-06 Neurocrine Biosciences, Inc. Synthesis of substituted pyrazolopyrimidines
US6472528B1 (en) * 1999-08-10 2002-10-29 Neurocrine Biosciences, Inc. Synthesis of substituted pyrazolopyrimidines
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US20030091632A1 (en) * 1999-08-26 2003-05-15 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
AU769856B2 (en) * 1999-09-02 2004-02-05 Neurocrine Biosciences, Inc. Polymorphs of N-methyl-N-(3-(3-(2-thienylcarbonyl)-pyrazol-(1,5-alpha)- pyrimidin-7-yl)phenyl)acetamide and compositions and methods related thereto
US6384221B1 (en) * 1999-09-02 2002-05-07 Neurocrine Biosciences, Inc. Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
DE10004790B4 (de) * 2000-02-01 2004-09-09 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung von Zaleplon, Verfahren zu seiner Herstellung und seine Verwendung
EP1272181A2 (en) 2000-04-13 2003-01-08 Synthon B.V. Modified release formulations containing a hypnotic agent
EP1526136A1 (en) * 2000-08-03 2005-04-27 Wyeth Polymorphs of zaleplon and methods for the preparation thereof
CA2417875C (en) * 2000-08-03 2008-12-09 Wyeth Polymorphs of zaleplon and methods for the preparation thereof
AR029780A1 (es) 2000-12-13 2003-07-16 Gador Sa Procedimiento mejorado para la obtencion de n-[3(3-ciano-pirazolo[1,5-a]pirimidin-7-il)fenil]-n-etil-acetamida
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DE02778962T1 (de) * 2001-06-12 2005-02-10 Biogal Gyogyszergyar Rt. VERFAHREN ZUR HERSTELLUNG VON N ç3 (3 CYANOPYRAZOLOç1,5 A!PYRIMIDIN 7 YL)PHENYL!-N-ETHYLACETAMID (ZALEPLON)
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ZA200406577B (en) * 2002-02-15 2006-06-28 Teva Gyogyzeryan Reszvenytarsa Powder composition comprising zaleplon of defined particle size distribution and pharmaceutical products made therefrom
PL207322B1 (pl) * 2002-05-14 2010-11-30 Adamed Społka Z Ograniczoną Odpowiedzialnością Sposób wytwarzania zaleplonu
AU2003297559A1 (en) * 2002-12-04 2004-06-23 Nascime Limited Method and compositions for treating anxiety
TWI252851B (en) * 2003-07-24 2006-04-11 Ferrer Int 7-substituted 3-nitro-pyrazolo[1,5-a]pyrimidines and compositions and methods related thereto
ES2222814B1 (es) * 2003-07-24 2005-12-01 Ferrer Internacional, S.A. 3-nitro-pirazolo(1,5-a)pirimidinas 7-sustituidas y composiciones y metodos relacionados.
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US20050277639A1 (en) * 2004-03-02 2005-12-15 Phil Skolnick 2-Pyridinyl[7-(substituted-pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl]methanones
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EP1884516A1 (en) * 2006-08-04 2008-02-06 Ferrer Internacional, S.A. Pyrazolo[1,5-a]pyrimidines, processes, uses and compositions
JP2010502722A (ja) * 2006-09-08 2010-01-28 ブレインセルス，インコーポレイティド ４−アシルアミノピリジン誘導体を含む組み合わせ
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US20100029657A1 (en) * 2008-02-29 2010-02-04 Wyeth Bridged, Bicyclic Heterocyclic or Spiro Bicyclic Heterocyclic Derivatives of Pyrazolo[1, 5-A]Pyrimidines, Methods for Preparation and Uses Thereof
US10478438B2 (en) 2008-10-16 2019-11-19 David Reed Helton Treatment of organophosphate exposure with ocinaplon
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CN102174048B (zh) * 2011-03-08 2014-09-17 中国人民解放军军事医学科学院放射与辐射医学研究所 一种催眠药的新多晶型β
CN102816163A (zh) * 2012-08-20 2012-12-12 四川禾邦阳光制药股份有限公司 扎来普隆的新晶型及制备方法
CN102775412B (zh) * 2012-08-21 2013-05-01 四川大学 一种镇静催眠的化合物及其制备方法和用途
CN102807569B (zh) * 2012-08-21 2015-02-25 四川大学 一种镇静催眠的化合物及其制备方法和用途
CN107973800B (zh) * 2017-12-29 2020-05-12 深圳蓝新科技有限公司 扎来普隆的制备方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4178449A (en) * 1978-04-17 1979-12-11 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
US4281000A (en) * 1979-07-09 1981-07-28 American Cyanamid Company Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents
US4521422A (en) * 1983-06-23 1985-06-04 American Cyanamid Company Aryl and heteroaryl[7-(aryl and heteroaryl)pyrazolo[1,5-a]pyrimidin-3-yl]methanones
NZ208554A (en) * 1983-06-23 1987-06-30 American Cyanamid Co (aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions
US4576943A (en) * 1984-10-09 1986-03-18 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines

Also Published As

Publication number Publication date
US4626538A (en) 1986-12-02
EP0208846B1 (en) 1993-11-18
NL990021I2 (nl) 2000-03-01
EP0208846A1 (en) 1987-01-21

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