NL8700656A - Nieuwe werkwijze. - Google Patents

Nieuwe werkwijze. Download PDF

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Publication number
NL8700656A
NL8700656A NL8700656A NL8700656A NL8700656A NL 8700656 A NL8700656 A NL 8700656A NL 8700656 A NL8700656 A NL 8700656A NL 8700656 A NL8700656 A NL 8700656A NL 8700656 A NL8700656 A NL 8700656A
Authority
NL
Netherlands
Prior art keywords
process according
acetone
methoxy
naphthaldehyde
takes place
Prior art date
Application number
NL8700656A
Other languages
English (en)
Dutch (nl)
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of NL8700656A publication Critical patent/NL8700656A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/73—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with hydrogenation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NL8700656A 1986-03-21 1987-03-20 Nieuwe werkwijze. NL8700656A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8607119 1986-03-21
GB868607119A GB8607119D0 (en) 1986-03-21 1986-03-21 Process

Publications (1)

Publication Number Publication Date
NL8700656A true NL8700656A (nl) 1987-10-16

Family

ID=10595051

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8700656A NL8700656A (nl) 1986-03-21 1987-03-20 Nieuwe werkwijze.

Country Status (8)

Country Link
JP (1) JPS62230744A (es)
CH (1) CH671014A5 (es)
DK (1) DK142387A (es)
ES (1) ES2004267A6 (es)
GB (1) GB8607119D0 (es)
GR (1) GR870454B (es)
NL (1) NL8700656A (es)
SE (1) SE8701168L (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756851A (en) * 1996-10-21 1998-05-26 Albemarle Corporation Production of nabumetone or precursors thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2242972A1 (es) * 1973-09-11 1975-04-04 Beecham Group Ltd
EP0003643A1 (en) * 1978-01-27 1979-08-22 Beecham Group Plc Process for the preparation of 4-(6-methoxy-2-naphthyl)-butan-2-one; 4-(6-methoxy-2-naphthyl)-4-hydroxybut-3-en-2-one and a process for its preparation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2242972A1 (es) * 1973-09-11 1975-04-04 Beecham Group Ltd
EP0003643A1 (en) * 1978-01-27 1979-08-22 Beecham Group Plc Process for the preparation of 4-(6-methoxy-2-naphthyl)-butan-2-one; 4-(6-methoxy-2-naphthyl)-4-hydroxybut-3-en-2-one and a process for its preparation

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 090, no. 1, 1 January 1979, Columbus, Ohio, US; abstract no. 000223, GOUDIE A C ET AL: "4-(6-Methoxy-2-naphthyl)butan-2-one and related analogs, a novel structural class of antiinflammatory compounds" *
CHEMICAL ABSTRACTS, vol. 103, no. 17, 28 October 1985, Columbus, Ohio, US; abstract no. 141569, LIU K ET AL: "Synthesis of nabumetone" *
J. MED. CHEM. (JMCMAR,00222623);78; VOL.21 (12); PP.1260-4, BEECHAM PHARM.;MED. RES. CENT.; HARLOW/ESSEX; ENGL. *
YIYAO GONGYE (YIGODN);85; VOL.16 (4); PP.147-9, JIANGSU PHARM. IND. CO.;PEOP. REP. CHINA (CN) *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756851A (en) * 1996-10-21 1998-05-26 Albemarle Corporation Production of nabumetone or precursors thereof
US5907069A (en) * 1996-10-21 1999-05-25 Albemarle Corporation Production of nabumetone or precursors thereof

Also Published As

Publication number Publication date
CH671014A5 (en) 1989-07-31
SE8701168D0 (sv) 1987-03-20
SE8701168L (sv) 1987-09-22
GB8607119D0 (en) 1986-04-30
DK142387A (da) 1987-09-22
DK142387D0 (da) 1987-03-19
GR870454B (en) 1987-07-10
ES2004267A6 (es) 1988-12-16
JPS62230744A (ja) 1987-10-09

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