NL8601240A - Plasminogeenactivator en trombolytisch geneesmiddel. - Google Patents

Plasminogeenactivator en trombolytisch geneesmiddel. Download PDF

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Publication number
NL8601240A
NL8601240A NL8601240A NL8601240A NL8601240A NL 8601240 A NL8601240 A NL 8601240A NL 8601240 A NL8601240 A NL 8601240A NL 8601240 A NL8601240 A NL 8601240A NL 8601240 A NL8601240 A NL 8601240A
Authority
NL
Netherlands
Prior art keywords
scu
plasminogen activator
blood
plasminogen
urokinase
Prior art date
Application number
NL8601240A
Other languages
English (en)
Dutch (nl)
Original Assignee
Leuven Res & Dev Vzw
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leuven Res & Dev Vzw filed Critical Leuven Res & Dev Vzw
Priority to NL8601240A priority Critical patent/NL8601240A/nl
Priority to ES198787200909T priority patent/ES2033295T3/es
Priority to JP62119978A priority patent/JPS62285784A/ja
Priority to AT87200909T priority patent/ATE78292T1/de
Priority to EP87200909A priority patent/EP0247674B1/en
Priority to DE8787200909T priority patent/DE3780357T2/de
Publication of NL8601240A publication Critical patent/NL8601240A/nl
Priority to GR920401735T priority patent/GR3005408T3/el

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NL8601240A 1986-05-15 1986-05-15 Plasminogeenactivator en trombolytisch geneesmiddel. NL8601240A (nl)

Priority Applications (7)

Application Number Priority Date Filing Date Title
NL8601240A NL8601240A (nl) 1986-05-15 1986-05-15 Plasminogeenactivator en trombolytisch geneesmiddel.
ES198787200909T ES2033295T3 (es) 1986-05-15 1987-05-15 Un metodo para preparar un activador de plasminogeno.
JP62119978A JPS62285784A (ja) 1986-05-15 1987-05-15 プラスミノ−ゲン活性化因子および血栓ほう壊組成物
AT87200909T ATE78292T1 (de) 1986-05-15 1987-05-15 Plasminogen-aktivator und thrombolytische zusammensetzung.
EP87200909A EP0247674B1 (en) 1986-05-15 1987-05-15 Plasminogen activator and thrombolytic composition
DE8787200909T DE3780357T2 (de) 1986-05-15 1987-05-15 Plasminogen-aktivator und thrombolytische zusammensetzung.
GR920401735T GR3005408T3 (da) 1986-05-15 1992-08-11

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8601240 1986-05-15
NL8601240A NL8601240A (nl) 1986-05-15 1986-05-15 Plasminogeenactivator en trombolytisch geneesmiddel.

Publications (1)

Publication Number Publication Date
NL8601240A true NL8601240A (nl) 1987-12-01

Family

ID=19848019

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8601240A NL8601240A (nl) 1986-05-15 1986-05-15 Plasminogeenactivator en trombolytisch geneesmiddel.

Country Status (7)

Country Link
EP (1) EP0247674B1 (da)
JP (1) JPS62285784A (da)
AT (1) ATE78292T1 (da)
DE (1) DE3780357T2 (da)
ES (1) ES2033295T3 (da)
GR (1) GR3005408T3 (da)
NL (1) NL8601240A (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0316068A1 (en) * 1987-10-09 1989-05-17 Collaborative Research Inc. Modified low molecular weight plasminogen activator and method of preparation
DE3735917A1 (de) * 1987-10-23 1989-05-03 Basf Ag Neue polypeptide, ihre herstellung und verwendung
GB8809093D0 (en) * 1988-04-18 1988-05-18 Erba Carlo Spa Low molecular weight derivatives of prourokinase
GB8919803D0 (en) * 1989-09-01 1989-10-18 Ciba Geigy Pharmaceutical compositions
DE4101736A1 (de) 1991-01-22 1992-07-23 Gruenenthal Gmbh Neue als plasminogenaktivatoren einsetzbare polypeptide, dafuer codierende plasmide und verfahren zu deren herstellung und deren verwendung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL68366A (en) * 1982-04-15 1990-08-31 Genentech Inc Process for expressing a gene encoding a protein comprising the enzymatic portion of human urokinase in a microorganism or cell culture
DE3486023T2 (de) * 1983-09-13 1993-06-24 Green Cross Corp Verfahren zur herstellung von urokinase zymogen.

Also Published As

Publication number Publication date
DE3780357D1 (de) 1992-08-20
JPS62285784A (ja) 1987-12-11
DE3780357T2 (de) 1992-12-17
ES2033295T3 (es) 1993-03-16
EP0247674A1 (en) 1987-12-02
GR3005408T3 (da) 1993-05-24
ATE78292T1 (de) 1992-08-15
EP0247674B1 (en) 1992-07-15

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