NL7605077A - Werkwijze ter bereiding van 7-acylamido 3-alkyl (of aryl) 3-cefem 4-carbonzuren en esters daarvan. - Google Patents

Werkwijze ter bereiding van 7-acylamido 3-alkyl (of aryl) 3-cefem 4-carbonzuren en esters daarvan.

Info

Publication number
NL7605077A
NL7605077A NL7605077A NL7605077A NL7605077A NL 7605077 A NL7605077 A NL 7605077A NL 7605077 A NL7605077 A NL 7605077A NL 7605077 A NL7605077 A NL 7605077A NL 7605077 A NL7605077 A NL 7605077A
Authority
NL
Netherlands
Prior art keywords
cefem
acylamido
aryl
esters
alkyl
Prior art date
Application number
NL7605077A
Other languages
English (en)
Dutch (nl)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NL7605077A publication Critical patent/NL7605077A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
NL7605077A 1975-05-12 1976-05-12 Werkwijze ter bereiding van 7-acylamido 3-alkyl (of aryl) 3-cefem 4-carbonzuren en esters daarvan. NL7605077A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/576,818 US4013651A (en) 1975-05-12 1975-05-12 3-substituted amino-cephalosporins

Publications (1)

Publication Number Publication Date
NL7605077A true NL7605077A (nl) 1976-11-16

Family

ID=24306128

Family Applications (3)

Application Number Title Priority Date Filing Date
NL7605077A NL7605077A (nl) 1975-05-12 1976-05-12 Werkwijze ter bereiding van 7-acylamido 3-alkyl (of aryl) 3-cefem 4-carbonzuren en esters daarvan.
NL7605078A NL7605078A (nl) 1975-05-12 1976-05-12 Werkwijze ter bereiding van 3-h 3-cefem 4-carbon- zuren en esters daarvan.
NL7605075A NL7605075A (nl) 1975-05-12 1976-05-12 Werkwijze ter bereiding van op de plaats 3 door aminogroepen gesubstitueerde cefalosporinever- bindingen.

Family Applications After (2)

Application Number Title Priority Date Filing Date
NL7605078A NL7605078A (nl) 1975-05-12 1976-05-12 Werkwijze ter bereiding van 3-h 3-cefem 4-carbon- zuren en esters daarvan.
NL7605075A NL7605075A (nl) 1975-05-12 1976-05-12 Werkwijze ter bereiding van op de plaats 3 door aminogroepen gesubstitueerde cefalosporinever- bindingen.

Country Status (11)

Country Link
US (3) US4013651A (cs)
JP (1) JPS51138697A (cs)
BE (1) BE841496A (cs)
CA (1) CA1074782A (cs)
CH (3) CH621123A5 (cs)
DE (1) DE2620308A1 (cs)
ES (3) ES447807A1 (cs)
GB (1) GB1544984A (cs)
IE (1) IE42540B1 (cs)
IL (1) IL49318A (cs)
NL (3) NL7605077A (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947413A (en) * 1972-11-13 1976-03-30 Merck & Co., Inc. 3-α-Substituted cephalosporins
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4434287A (en) 1975-02-20 1984-02-28 Ciba-Geigy Corporation Cephalosporin derivatives
US4550162A (en) * 1975-02-20 1985-10-29 Ciba-Geigy Corporation Process for the manufacture of enol derivatives
JPS543087A (en) * 1977-06-03 1979-01-11 Fujisawa Pharmaceut Co Ltd Preparation of cephalosporin compound
US4244885A (en) * 1977-12-08 1981-01-13 Yeda Research And Development Co. Ltd. α-Substituted-3-(halomethyl)-4-hydroxybenzeneacetic acids
US4436903A (en) * 1980-12-22 1984-03-13 Ciba-Geigy Corporation Process for the production of 7 β-substituted-3-unsubstituted-3-cephem-4-carboxylic acid compounds
US4533497A (en) * 1982-12-27 1985-08-06 Eli Lilly And Company N-ethylidene azetidinones
EP0327239B1 (en) * 1988-01-25 1994-06-22 Eli Lilly And Company 1-carbacephalosporin antibiotics
US5019571A (en) * 1988-01-25 1991-05-28 Eli Lilly And Company 1-carbacephalosporin antibiotics
WO2017190043A1 (en) * 2016-04-29 2017-11-02 University Of Kansas Cephalosporin-type compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE412238B (sv) * 1971-05-24 1980-02-25 Ciba Geigy Forfarande for framstellning av 7 beta-amino-cefem-4-karboxylsyraforeningar genom dekarbonylering av en 3-formyl-cefem-4-karboxylsyraforening
US4001226A (en) * 1974-12-04 1977-01-04 Eli Lilly And Company 3-(substituted)carbonylamino cephem derivatives
JPS609516B2 (ja) * 1975-03-07 1985-03-11 塩野義製薬株式会社 セフエム骨格の環化製法
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen

Also Published As

Publication number Publication date
ES447805A1 (es) 1978-04-01
US4065621A (en) 1977-12-27
GB1544984A (en) 1979-04-25
IL49318A (en) 1980-03-31
CH621123A5 (cs) 1981-01-15
JPS51138697A (en) 1976-11-30
ES447806A1 (es) 1977-10-01
IE42540L (en) 1976-11-12
US4013651A (en) 1977-03-22
BE841496A (fr) 1976-11-08
CH619958A5 (cs) 1980-10-31
CH623054A5 (cs) 1981-05-15
NL7605078A (nl) 1976-11-16
IL49318A0 (en) 1976-05-31
DE2620308A1 (de) 1976-11-25
IE42540B1 (en) 1980-08-27
CA1074782A (en) 1980-04-01
NL7605075A (nl) 1976-11-16
US4065618A (en) 1977-12-27
ES447807A1 (es) 1977-10-01

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Legal Events

Date Code Title Description
BV The patent application has lapsed