NL7603653A - Werkwijze voor het bereiden van nieuwe middelen tegen cholesterolemie. - Google Patents

Werkwijze voor het bereiden van nieuwe middelen tegen cholesterolemie.

Info

Publication number
NL7603653A
NL7603653A NL7603653A NL7603653A NL7603653A NL 7603653 A NL7603653 A NL 7603653A NL 7603653 A NL7603653 A NL 7603653A NL 7603653 A NL7603653 A NL 7603653A NL 7603653 A NL7603653 A NL 7603653A
Authority
NL
Netherlands
Prior art keywords
cholesterolemia
agents
preparing new
preparing
new
Prior art date
Application number
NL7603653A
Other languages
English (en)
Dutch (nl)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NL7603653A publication Critical patent/NL7603653A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0206—Polyalkylene(poly)amines
    • C08G73/0213—Preparatory process
    • C08G73/0226—Quaternisation of polyalkylene(poly)amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C07C209/74—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton by halogenation, hydrohalogenation, dehalogenation, or dehydrohalogenation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
NL7603653A 1975-04-23 1976-04-07 Werkwijze voor het bereiden van nieuwe middelen tegen cholesterolemie. NL7603653A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/570,910 US4016209A (en) 1975-04-23 1975-04-23 3-[N'-(3-Halopropyl)-N-'-methylamino]-N,N,N-trimethyl-1-propanaminium halide and acid addition salts thereof

Publications (1)

Publication Number Publication Date
NL7603653A true NL7603653A (nl) 1976-10-26

Family

ID=24281556

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7603653A NL7603653A (nl) 1975-04-23 1976-04-07 Werkwijze voor het bereiden van nieuwe middelen tegen cholesterolemie.

Country Status (29)

Country Link
US (3) US4016209A (pl)
JP (1) JPS51136605A (pl)
AR (1) AR223301A1 (pl)
AT (1) AT354099B (pl)
AU (1) AU506771B2 (pl)
BE (1) BE841005A (pl)
CA (1) CA1082228A (pl)
CS (1) CS190529B2 (pl)
DD (2) DD131564A5 (pl)
DE (1) DE2617524A1 (pl)
DK (1) DK164576A (pl)
EG (1) EG12656A (pl)
ES (1) ES447059A1 (pl)
FI (1) FI760939A (pl)
FR (2) FR2308375A1 (pl)
GB (2) GB1525762A (pl)
GR (1) GR59848B (pl)
HU (1) HU175963B (pl)
IE (1) IE44097B1 (pl)
IL (1) IL49392A (pl)
LU (1) LU74759A1 (pl)
NL (1) NL7603653A (pl)
NO (1) NO761208L (pl)
NZ (1) NZ180581A (pl)
PH (1) PH14726A (pl)
PL (1) PL113974B1 (pl)
PT (1) PT65031B (pl)
SE (1) SE7604094L (pl)
ZA (1) ZA762407B (pl)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
WO1996021454A1 (en) * 1995-01-12 1996-07-18 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
WO1996039156A2 (en) * 1995-06-06 1996-12-12 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US8187631B2 (en) 1999-10-19 2012-05-29 Genzyme Corporation Direct compression polymer tablet core
US8986669B2 (en) 2005-09-02 2015-03-24 Genzyme Corporation Method for removing phosphate and polymer used therefore
US11267924B2 (en) 2014-12-18 2022-03-08 Genzyme Corporation Crosslinked polydiallymine copolymers for the treatment of type 2 diabetes

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093657A (en) * 1976-04-09 1978-06-06 Merck & Co., Inc. Process for preparing monomer of bile acid sequestrant polymer
FR2356425A1 (fr) * 1976-07-01 1978-01-27 Roussel Uclaf Application a titre de medicaments de derives organiques de la montmorillonite
US4185088A (en) * 1977-02-17 1980-01-22 Merck & Co., Inc. Non-adhesive ionene quaternary polymer compositions useful as bile acid sequestrants
NZ191762A (en) * 1978-10-19 1982-09-14 Merck & Co Inc Hypocholesteremic composition containing cholesterol synthesis inhibitor and anion exchange resin
IT1185484B (it) * 1985-10-31 1987-11-12 Pirelli Cavi Spa Cavo elettrico e materiale per il rivestimento di conduttori elettrici avente funzione di isolante e/o di guaina
US4824602A (en) * 1986-10-27 1989-04-25 The Procter & Gamble Company Processes for purification of quaternary cationic surfactant materials and cosmetic compositions containing same
US5349089A (en) * 1989-07-07 1994-09-20 National Starch And Chemical Investment Holding Corporation Reagent for preparing polycationic polysaccharides
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US6129910A (en) * 1993-06-02 2000-10-10 Geltex Pharmaceuticals, Inc. Water-insoluble noncrosslinked bile acid sequestrants
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
TW474813B (en) * 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
CN1108801C (zh) * 1995-01-12 2003-05-21 吉尔特药品公司 用于口服的磷酸盐结合聚合物
US20040053208A1 (en) * 1995-08-29 2004-03-18 V. I. TECHNOLOGIES, Inc. Methods to selectively inactivate parasites in biological compositions
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
GB2321900A (en) * 1997-02-11 1998-08-12 Procter & Gamble Cationic surfactants
US6423754B1 (en) * 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6352695B1 (en) * 1997-10-03 2002-03-05 V.I. Technologies, Inc. Methods and compositions for the selective modification of nucleic acids
US6093564A (en) * 1997-10-03 2000-07-25 V.I. Technologies, Inc. Methods and compositions for the selective modification of nucleic acids
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US6617100B2 (en) 1998-09-25 2003-09-09 V.I. Technologies, Inc. Solid phase quenching systems
US6403359B1 (en) 1998-09-25 2002-06-11 V. I. TECHNOLOGIES, Inc. Solid phase quenching systems
EP3000460A1 (en) 2005-09-15 2016-03-30 Genzyme Corporation Sachet formulation for amine polymers

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2163181A (en) * 1935-03-01 1939-06-20 Ig Farbenindustrie Ag Process of producing halogen-alkyl amines or their salts
US2884057A (en) * 1954-02-25 1959-04-28 American Cyanamid Co Paper of improved dry strength and method of making same
US3147065A (en) * 1960-05-02 1964-09-01 Minnesota Mining & Mfg Quaternized halomethylamides
US3234150A (en) * 1960-06-16 1966-02-08 Nalco Chemical Co Strong base anion exchange resins from polymeric tertiary amines
AT243774B (de) * 1961-02-07 1965-11-25 American Cyanamid Co Verfahren zur Herstellung von neuen Hydroxydiaminen
NL282900A (pl) * 1961-09-22 1900-01-01
US3372129A (en) * 1964-10-06 1968-03-05 Nalco Chemical Co Method of preparing polyamines
US3370048A (en) * 1965-03-15 1968-02-20 Eastman Kodak Co Process for the preparation of new linear condensation polymers
CH508583A (de) * 1968-01-31 1971-06-15 Bayer Ag Verfahren zur Herstellung von 3-Aminopropanolen
US3493615A (en) * 1968-10-28 1970-02-03 Colgate Palmolive Co Surfactant anti-microbial compounds
NL7103340A (pl) * 1970-03-19 1971-09-21
US3632507A (en) * 1970-06-30 1972-01-04 Standard Brands Chem Ind Inc Flocculation of particles dispersed in aqueous media and flocculants used therein
CH375271A4 (pl) * 1971-03-15 1974-03-15
CH568958A5 (pl) * 1972-04-28 1975-11-14 Sandoz Ag

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7014846B2 (en) 1993-08-11 2006-03-21 Genzyme Corporation Phosphate-binding polymers for oral administration
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
EP0716606A1 (en) * 1993-08-11 1996-06-19 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US7459151B2 (en) 1993-08-11 2008-12-02 Genzyme Corporation Phosphate-binding polymers for oral administration
EP0716606A4 (en) * 1993-08-11 1999-12-22 Geltex Pharma Inc PHOSPHATE-BINDING POLYMERS FOR ORAL ADMINISTRATION
EP1133989A2 (en) * 1993-08-11 2001-09-19 Geltex Pharmaceuticals, Inc. Polymer compositions for use in therapy
US6509013B1 (en) 1993-08-11 2003-01-21 Geltex Pharmaceuticals, Inc. Method of making phosphate-binding polymers for oral administration
EP1133989A3 (en) * 1993-08-11 2004-05-12 Genzyme Corporation Polymer compositions for use in therapy
US6858203B2 (en) 1993-08-11 2005-02-22 Genzyme Corporation Method of making phosphate-binding polymers for oral administration
WO1996021454A1 (en) * 1995-01-12 1996-07-18 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
WO1996039156A3 (en) * 1995-06-06 1997-03-27 Geltex Pharma Inc Phosphate-binding polymers for oral administration
WO1996039156A2 (en) * 1995-06-06 1996-12-12 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US8187631B2 (en) 1999-10-19 2012-05-29 Genzyme Corporation Direct compression polymer tablet core
US9579343B2 (en) 1999-10-19 2017-02-28 Genzyme Corporation Direct compression polymer tablet core
US9931358B2 (en) 1999-10-19 2018-04-03 Genzyme Corporation Direct compression polymer tablet core
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US8808738B2 (en) 2004-11-01 2014-08-19 Genzyme Corporation Aliphatic amine polymer salts for tableting
US9555056B2 (en) 2004-11-01 2017-01-31 Genzyme Corporation Aliphatic amine polymer salts for tableting
US9895315B2 (en) 2004-11-01 2018-02-20 Genzyme Corporation Aliphatic amine polymer salts for tableting
US8986669B2 (en) 2005-09-02 2015-03-24 Genzyme Corporation Method for removing phosphate and polymer used therefore
US11267924B2 (en) 2014-12-18 2022-03-08 Genzyme Corporation Crosslinked polydiallymine copolymers for the treatment of type 2 diabetes

Also Published As

Publication number Publication date
FR2308375B1 (pl) 1981-07-31
IE44097L (en) 1976-10-23
AU1299176A (en) 1977-10-20
BE841005A (fr) 1976-10-22
SE7604094L (sv) 1976-10-24
PT65031A (en) 1976-05-01
DE2617524A1 (de) 1976-11-04
FI760939A (pl) 1976-10-24
LU74759A1 (pl) 1977-02-04
IL49392A (en) 1980-07-31
AU506771B2 (en) 1980-01-24
ZA762407B (en) 1977-11-30
EG12656A (en) 1979-06-30
US4156693A (en) 1979-05-29
AT354099B (de) 1979-12-27
IE44097B1 (en) 1981-08-12
CS190529B2 (en) 1979-05-31
FR2357528B1 (pl) 1980-09-26
FR2308375A1 (fr) 1976-11-19
IL49392A0 (en) 1976-06-30
CA1082228A (en) 1980-07-22
DD131645A5 (de) 1978-07-12
GB1525762A (en) 1978-09-20
PH14726A (en) 1981-11-13
FR2357528A1 (fr) 1978-02-03
US4098726A (en) 1978-07-04
DD131564A5 (de) 1978-07-05
US4016209A (en) 1977-04-05
PT65031B (en) 1978-04-03
NZ180581A (en) 1978-11-13
GR59848B (en) 1978-03-07
GB1539006A (en) 1979-01-24
DK164576A (da) 1976-10-24
ES447059A1 (es) 1977-11-16
ATA290976A (de) 1979-05-15
JPS51136605A (en) 1976-11-26
NO761208L (pl) 1976-10-26
AR223301A1 (es) 1981-08-14
PL113974B1 (en) 1981-01-31
HU175963B (en) 1980-11-28

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Legal Events

Date Code Title Description
BV The patent application has lapsed