NL7503849A - Werkwijze voor de bereiding van een geneesmid- del met antidiarree werkzaamheid, alsmede voor de bereiding van daarvoor geschikte verbindin- gen. - Google Patents
Werkwijze voor de bereiding van een geneesmid- del met antidiarree werkzaamheid, alsmede voor de bereiding van daarvoor geschikte verbindin- gen.Info
- Publication number
- NL7503849A NL7503849A NL7503849A NL7503849A NL7503849A NL 7503849 A NL7503849 A NL 7503849A NL 7503849 A NL7503849 A NL 7503849A NL 7503849 A NL7503849 A NL 7503849A NL 7503849 A NL7503849 A NL 7503849A
- Authority
- NL
- Netherlands
- Prior art keywords
- preparation
- antidiarrree
- efficacy
- procedure
- well
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US456755A US3917615A (en) | 1974-04-01 | 1974-04-01 | 1,1-Diaryl-1-oxadiazol-alkylamines |
Publications (1)
Publication Number | Publication Date |
---|---|
NL7503849A true NL7503849A (nl) | 1975-10-03 |
Family
ID=23814026
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7503856A NL7503856A (nl) | 1974-04-01 | 1975-04-01 | Werkwijze voor de bereiding van een geneesmid- del met antidiarree werkzaamheid, alsmede voor de bereiding van daarvoor geschikte verbindin- gen. |
NL7503849A NL7503849A (nl) | 1974-04-01 | 1975-04-01 | Werkwijze voor de bereiding van een geneesmid- del met antidiarree werkzaamheid, alsmede voor de bereiding van daarvoor geschikte verbindin- gen. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7503856A NL7503856A (nl) | 1974-04-01 | 1975-04-01 | Werkwijze voor de bereiding van een geneesmid- del met antidiarree werkzaamheid, alsmede voor de bereiding van daarvoor geschikte verbindin- gen. |
Country Status (26)
Country | Link |
---|---|
US (2) | US3917615A (cs) |
JP (2) | JPS5939434B2 (cs) |
AR (2) | AR206425A1 (cs) |
AT (2) | AT340916B (cs) |
BE (2) | BE827323A (cs) |
CA (2) | CA1053672A (cs) |
CH (2) | CH613964A5 (cs) |
CS (1) | CS194718B2 (cs) |
DE (2) | DE2514229A1 (cs) |
DK (2) | DK137275A (cs) |
EG (1) | EG12104A (cs) |
ES (2) | ES436044A1 (cs) |
FI (2) | FI63572C (cs) |
FR (2) | FR2265367B1 (cs) |
GB (2) | GB1494943A (cs) |
HU (1) | HU170747B (cs) |
IE (2) | IE40895B1 (cs) |
IL (2) | IL46959A (cs) |
NL (2) | NL7503856A (cs) |
NO (2) | NO142174C (cs) |
OA (1) | OA04914A (cs) |
PH (1) | PH11423A (cs) |
PL (1) | PL99553B1 (cs) |
SE (2) | SE420491B (cs) |
YU (1) | YU39200B (cs) |
ZA (2) | ZA751193B (cs) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4003904A (en) * | 1974-04-01 | 1977-01-18 | G. D. Searle & Co. | Anti-diarrheal oxadiazoles |
US4057549A (en) * | 1975-04-16 | 1977-11-08 | G. D. Searle & Co. | Triarylpropyl-azabicyclooctanes |
US4086227A (en) * | 1975-04-16 | 1978-04-25 | G. D. Searle & Co. | Novel anti-diarrheal 4-azatricyclo[4.3.1.13,8 ] undecane derivatives |
US3998832A (en) * | 1975-04-16 | 1976-12-21 | G. D. Searle & Co. | Anti-diarrheal compounds |
US4025524A (en) * | 1975-04-16 | 1977-05-24 | G. D. Searle & Co. | 2-{3-[4-Azatricyclo(4.3.1.13,8)undecan-4-yl]-1,1-diphenylpropyl}-5-methyl-1,3,4-oxadiazole and congeners |
US3996214A (en) * | 1976-02-23 | 1976-12-07 | G. D. Searle & Co. | 5-(1,1-Diphenyl-4-(cyclic amino) but-2-trans-en-1-yl)-2-alkyl-1,3,4-oxadiazoles and intermediates thereto |
US4013668A (en) * | 1976-03-10 | 1977-03-22 | G. D. Searle & Co. | 5-(1,1-diphenyl-3-(5- or 6-hydroxy-2-azabicyclo(2.2.2)oct-2-yl)propyl)-2-alkyl-1,3,4-oxadiazoles and related compounds |
US4012393A (en) * | 1976-03-22 | 1977-03-15 | G. D. Searle & Co. | 2-[5-(CYCLIC AMINO) ETHYL-10,11-DIHYDRO-5H-dibenzo[a,d]-cyclohepten-5- yl]-5 |
US4028364A (en) * | 1976-07-06 | 1977-06-07 | G. D. Searle & Co. | 2-Azabicyclo[2.2.2.]octan-2-yl-diphenyl-alkanones and related compounds |
US4053477A (en) * | 1976-09-20 | 1977-10-11 | G. D. Searle & Co. | 5-(1,1-diphenyl-3-(4-phenylpiperidino)propyl)-2-methyl-1,3,4-oxadiazole and related compounds |
US4194045A (en) * | 1977-12-27 | 1980-03-18 | G. D. Searle & Co. | 1-(3,3-Diaryl-3-oxadiazolalkyl)-4-phenyl-4-piperidinomethanols and related compounds |
US4203990A (en) * | 1979-04-30 | 1980-05-20 | G. D. Searle & Co. | Anti-diarrheal 2-substituted quinuclidines |
US4203989A (en) * | 1979-04-30 | 1980-05-20 | G. D. Searle & Co. | Anti-diarrheal diaryl-(1-azabicyclo(2.2.2)octan-2-yl)-alkanols and related compounds |
US4596801A (en) | 1983-03-24 | 1986-06-24 | Chugai Seiyaku Kabushiki Kaisha | 4H-3,1-benzoxazine derivatives, process for producing the same and agricultural or horticultural fungicide containing the same |
JPS61194917A (ja) * | 1985-02-23 | 1986-08-29 | Matsushita Electric Works Ltd | 遅れスイツチ |
JPS61195022A (ja) * | 1985-02-25 | 1986-08-29 | Matsushita Electric Works Ltd | 遅れスイツチ |
GB8830226D0 (en) * | 1988-12-23 | 1989-02-22 | Beecham Group Plc | Novel compounds |
DK40890D0 (da) * | 1990-02-16 | 1990-02-16 | Ferrosan As | Substituerede urinstofforbindelser, deres fremstilling og anvendelse |
US5889038A (en) * | 1996-03-20 | 1999-03-30 | Children's Hospital | Methods and products for treating diarrhea and scours: use of clotrimazole and related aromatic compounds |
WO2012164573A2 (en) | 2011-05-27 | 2012-12-06 | Reliance Industries Ltd., | Hydrolysis and esterification with acid catalysts |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3141019A (en) * | 1964-07-14 | Chaohj | ||
US3299044A (en) * | 1964-05-13 | 1967-01-17 | Searle & Co | Complex n-substituted azabicycloalkanes |
FR1469022A (fr) * | 1965-12-14 | 1967-02-10 | Chimie Et Synthese De Picardie | Nouveaux dérivés oxadiazoliques et leur procédé de préparation |
GB1174411A (en) * | 1966-03-02 | 1969-12-17 | Aspro Nicholas Ltd | Novel Benzothiophen Compounds, Compositions containing them and processes for their manufacture |
GB1231829A (cs) * | 1968-09-19 | 1971-05-12 | ||
US3720685A (en) * | 1970-07-15 | 1973-03-13 | Squibb & Sons Inc | 3-amino-5-benzyl-1,2,4-oxadiazoles |
-
1974
- 1974-04-01 US US456755A patent/US3917615A/en not_active Expired - Lifetime
-
1975
- 1975-01-01 AR AR258169A patent/AR206425A1/es active
- 1975-02-26 ZA ZA00751193A patent/ZA751193B/xx unknown
- 1975-03-26 ES ES436044A patent/ES436044A1/es not_active Expired
- 1975-03-28 HU HUSE1776A patent/HU170747B/hu unknown
- 1975-03-28 FR FR7509995A patent/FR2265367B1/fr not_active Expired
- 1975-03-28 BE BE154889A patent/BE827323A/xx not_active IP Right Cessation
- 1975-03-28 CS CS752162A patent/CS194718B2/cs unknown
- 1975-03-28 IL IL46959A patent/IL46959A/xx unknown
- 1975-03-28 BE BE154890A patent/BE827324A/xx not_active IP Right Cessation
- 1975-03-28 FR FR7509996A patent/FR2265376B1/fr not_active Expired
- 1975-03-31 IL IL46966A patent/IL46966A/en unknown
- 1975-03-31 EG EG179/75A patent/EG12104A/xx active
- 1975-03-31 YU YU00816/75A patent/YU39200B/xx unknown
- 1975-03-31 JP JP50039024A patent/JPS5939434B2/ja not_active Expired
- 1975-03-31 ES ES436160A patent/ES436160A1/es not_active Expired
- 1975-03-31 JP JP50039025A patent/JPS5936631B2/ja not_active Expired
- 1975-03-31 OA OA55456A patent/OA04914A/xx unknown
- 1975-03-31 PH PH16986A patent/PH11423A/en unknown
- 1975-04-01 CA CA223,487A patent/CA1053672A/en not_active Expired
- 1975-04-01 DE DE19752514229 patent/DE2514229A1/de not_active Ceased
- 1975-04-01 SE SE7503688A patent/SE420491B/xx not_active IP Right Cessation
- 1975-04-01 SE SE7503689A patent/SE420492B/xx unknown
- 1975-04-01 FI FI750965A patent/FI63572C/fi not_active IP Right Cessation
- 1975-04-01 GB GB13184/75A patent/GB1494943A/en not_active Expired
- 1975-04-01 PL PL1975179255A patent/PL99553B1/pl unknown
- 1975-04-01 ZA ZA00751986A patent/ZA751986B/xx unknown
- 1975-04-01 NL NL7503856A patent/NL7503856A/xx not_active Application Discontinuation
- 1975-04-01 DK DK137275A patent/DK137275A/da not_active IP Right Cessation
- 1975-04-01 NL NL7503849A patent/NL7503849A/xx not_active Application Discontinuation
- 1975-04-01 CH CH410875A patent/CH613964A5/xx not_active IP Right Cessation
- 1975-04-01 DK DK137375A patent/DK137375A/da not_active Application Discontinuation
- 1975-04-01 GB GB1318675A patent/GB1456943A/en not_active Expired
- 1975-04-01 FI FI750966A patent/FI61895C/fi not_active IP Right Cessation
- 1975-04-01 DE DE19752514183 patent/DE2514183A1/de not_active Withdrawn
- 1975-04-01 NO NO751104A patent/NO142174C/no unknown
- 1975-04-01 CA CA223,485A patent/CA1067498A/en not_active Expired
- 1975-04-01 NO NO751103A patent/NO142173C/no unknown
- 1975-04-01 AT AT245175A patent/AT340916B/de not_active IP Right Cessation
- 1975-04-01 AT AT245275A patent/AT342045B/de not_active IP Right Cessation
- 1975-04-01 CH CH410975A patent/CH614205A5/xx not_active IP Right Cessation
- 1975-04-02 IE IE713/75A patent/IE40895B1/xx unknown
- 1975-04-02 IE IE712/75A patent/IE40894B1/xx unknown
-
1976
- 1976-07-15 AR AR20634176D patent/AR206341A1/es active
- 1976-09-02 US US05/719,775 patent/USRE29556E/en not_active Expired - Lifetime
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BA | A request for search or an international-type search has been filed | ||
BB | A search report has been drawn up | ||
BC | A request for examination has been filed | ||
A85 | Still pending on 85-01-01 | ||
BV | The patent application has lapsed |