NL7216702A - Antiinflammatory aminophenoxyacetamides - from nitrophenoxyacetamides by catalytic redn - Google Patents

Antiinflammatory aminophenoxyacetamides - from nitrophenoxyacetamides by catalytic redn

Info

Publication number
NL7216702A
NL7216702A NL7216702A NL7216702A NL7216702A NL 7216702 A NL7216702 A NL 7216702A NL 7216702 A NL7216702 A NL 7216702A NL 7216702 A NL7216702 A NL 7216702A NL 7216702 A NL7216702 A NL 7216702A
Authority
NL
Netherlands
Prior art keywords
nitrophenoxyacetamides
aryl
antiinflammatory
aminophenoxyacetamides
redn
Prior art date
Application number
NL7216702A
Other versions
NL148305B (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7218646A external-priority patent/FR2185399A2/en
Priority claimed from FR7218645A external-priority patent/FR2185395A1/en
Application filed filed Critical
Publication of NL7216702A publication Critical patent/NL7216702A/en
Publication of NL148305B publication Critical patent/NL148305B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D333/40—Thiophene-2-carboxylic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Cpds. of formula (I) and acid addn. salts (where Z = NH2,RCONH (esp. formyl or acetyl), NHR1,NR2R3 or NHCONR4R4; R = H, a linear or branched, satd. or unsatd. cyclic or heterocyclic, aliphatic, aryl or aryloxy-aliphatic, carboxyaliphatic or aromatic residue; R1, R2, R3=alkyl, aryl or aralkyl; R4, R5 = H, alkyl, aryl, aralkyl or alkylamino) are appetite depressants, anxiolytics and antiinflammatory agents. Prepd. from the corresp. nitrophenoxyacetamides (I; A=NO2) by redn. with H2 in presence of Pt oxide.
NL7216702A 1972-05-25 1972-12-08 PROCESS FOR THE PREPARATION OF MEDICINAL PRODUCTS CONTAINING A PHENOXYACETIC ACID (1-METHYL-2- (M-TRIFLUORMETHYLPHENYL) -ETHYLAMIDE) AS A THERAPEUTIC ACTIVE SUBSTANCE, PREPARED BY MEDICINES, PREPARED, PREPARED BY MEDICINES NL148305B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7218646A FR2185399A2 (en) 1971-06-11 1972-05-25 Antiinflammatory aminophenoxyacetamides - from nitrophenoxyacetamides by catalytic redn
FR7218645A FR2185395A1 (en) 1972-05-25 1972-05-25 Antiinflammatory aminophenoxyacetamides - from nitrophenoxyacetamides by catalytic redn

Publications (2)

Publication Number Publication Date
NL7216702A true NL7216702A (en) 1973-11-27
NL148305B NL148305B (en) 1976-01-15

Family

ID=26217099

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7216702A NL148305B (en) 1972-05-25 1972-12-08 PROCESS FOR THE PREPARATION OF MEDICINAL PRODUCTS CONTAINING A PHENOXYACETIC ACID (1-METHYL-2- (M-TRIFLUORMETHYLPHENYL) -ETHYLAMIDE) AS A THERAPEUTIC ACTIVE SUBSTANCE, PREPARED BY MEDICINES, PREPARED, PREPARED BY MEDICINES

Country Status (3)

Country Link
ES (1) ES409040A1 (en)
NL (1) NL148305B (en)
SE (1) SE400554B (en)

Also Published As

Publication number Publication date
SE400554B (en) 1978-04-03
NL148305B (en) 1976-01-15
ES409040A1 (en) 1976-04-01

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Legal Events

Date Code Title Description
V1 Lapsed because of non-payment of the annual fee
NL80 Abbreviated name of patent owner mentioned of already nullified patent

Owner name: BUZAS