FR2140338A1 - Antiinflammatory aminophenoxyacetamides - from nitrophenoxyacetamides by catalytic redn - Google Patents

Antiinflammatory aminophenoxyacetamides - from nitrophenoxyacetamides by catalytic redn

Info

Publication number
FR2140338A1
FR2140338A1 FR7121267A FR7121267A FR2140338A1 FR 2140338 A1 FR2140338 A1 FR 2140338A1 FR 7121267 A FR7121267 A FR 7121267A FR 7121267 A FR7121267 A FR 7121267A FR 2140338 A1 FR2140338 A1 FR 2140338A1
Authority
FR
France
Prior art keywords
nitrophenoxyacetamides
aryl
antiinflammatory
aminophenoxyacetamides
redn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7121267A
Other languages
French (fr)
Other versions
FR2140338B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BUZAS ANDRE FR
Original Assignee
BUZAS ANDRE FR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE791772D priority Critical patent/BE791772A/en
Application filed by BUZAS ANDRE FR filed Critical BUZAS ANDRE FR
Priority to FR7121267A priority patent/FR2140338A1/en
Priority to FR7218646A priority patent/FR2185399A2/en
Priority to US00261106A priority patent/US3843647A/en
Priority to DE2227846A priority patent/DE2227846C3/en
Priority to GB2708672A priority patent/GB1380784A/en
Publication of FR2140338A1 publication Critical patent/FR2140338A1/en
Application granted granted Critical
Publication of FR2140338B1 publication Critical patent/FR2140338B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Cpds. of formula (I) and acid addn. salts (where Z = NH2,RCONH (esp. formyl or acetyl), NHR1,NR2R3 or NHCONR4R4; R = H, a linear or branched, satd. or unsatd. cyclic or heterocyclic, aliphatic, aryl or aryloxy-aliphatic, carboxyaliphatic or aromatic residue; R1, R2, R3=alkyl, aryl or aralkyl; R4, R5 = H, alkyl, aryl, aralkyl or alkylamino) are appetite depressants, anxiolytics and antiinflammatory agents. Prepd. from the corresp. nitrophenoxyacetamides (I; A=NO2) by redn. with H2 in presence of Pt oxide.
FR7121267A 1971-06-11 1971-06-11 Antiinflammatory aminophenoxyacetamides - from nitrophenoxyacetamides by catalytic redn Granted FR2140338A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
BE791772D BE791772A (en) 1971-06-11 PHENOXY-ACETIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR7121267A FR2140338A1 (en) 1971-06-11 1971-06-11 Antiinflammatory aminophenoxyacetamides - from nitrophenoxyacetamides by catalytic redn
FR7218646A FR2185399A2 (en) 1971-06-11 1972-05-25 Antiinflammatory aminophenoxyacetamides - from nitrophenoxyacetamides by catalytic redn
US00261106A US3843647A (en) 1971-06-11 1972-06-08 Derivatives of phenoxyacetic acids
DE2227846A DE2227846C3 (en) 1971-06-11 1972-06-08 Substituted phenoxyacetic acid amides, process for their preparation and pharmaceutical composition
GB2708672A GB1380784A (en) 1971-06-11 1972-06-09 Derivatives of phenoxyacetic acids their preparation and their use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7121267A FR2140338A1 (en) 1971-06-11 1971-06-11 Antiinflammatory aminophenoxyacetamides - from nitrophenoxyacetamides by catalytic redn

Publications (2)

Publication Number Publication Date
FR2140338A1 true FR2140338A1 (en) 1973-01-19
FR2140338B1 FR2140338B1 (en) 1974-08-30

Family

ID=9078503

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7121267A Granted FR2140338A1 (en) 1971-06-11 1971-06-11 Antiinflammatory aminophenoxyacetamides - from nitrophenoxyacetamides by catalytic redn

Country Status (1)

Country Link
FR (1) FR2140338A1 (en)

Also Published As

Publication number Publication date
FR2140338B1 (en) 1974-08-30

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Legal Events

Date Code Title Description
GC Lien (pledge) constituted
CL Concession to grant licenses
ST Notification of lapse