FR2182943A1 - Cis-dihalo-bis(ethyleneimine) platinum (ii) derivs - anti-cancer agents - Google Patents

Cis-dihalo-bis(ethyleneimine) platinum (ii) derivs - anti-cancer agents

Info

Publication number
FR2182943A1
FR2182943A1 FR7312664A FR7312664A FR2182943A1 FR 2182943 A1 FR2182943 A1 FR 2182943A1 FR 7312664 A FR7312664 A FR 7312664A FR 7312664 A FR7312664 A FR 7312664A FR 2182943 A1 FR2182943 A1 FR 2182943A1
Authority
FR
France
Prior art keywords
derivs
dihalo
ethyleneimine
cis
platinum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7312664A
Other languages
French (fr)
Other versions
FR2182943B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rustenburg Platinum Mines Ltd
Original Assignee
Rustenburg Platinum Mines Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rustenburg Platinum Mines Ltd filed Critical Rustenburg Platinum Mines Ltd
Publication of FR2182943A1 publication Critical patent/FR2182943A1/en
Application granted granted Critical
Publication of FR2182943B1 publication Critical patent/FR2182943B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/22Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage

Abstract

Title cpds. are of formula I, where R1-R8 = H, opt. subst. alkyl, aryl, aralkyl or alkaryl, hal, pseudohal, NO2, NH2, CONH2, OH, CHO, CO2H or SO3H.
FR7312664A 1972-04-10 1973-04-09 Cis-dihalo-bis(ethyleneimine) platinum (ii) derivs - anti-cancer agents Granted FR2182943A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1635072 1972-04-10
GB2138972 1972-05-08

Publications (2)

Publication Number Publication Date
FR2182943A1 true FR2182943A1 (en) 1973-12-14
FR2182943B1 FR2182943B1 (en) 1976-12-31

Family

ID=26251984

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7312664A Granted FR2182943A1 (en) 1972-04-10 1973-04-09 Cis-dihalo-bis(ethyleneimine) platinum (ii) derivs - anti-cancer agents

Country Status (4)

Country Link
JP (1) JPS4913316A (en)
DE (1) DE2318020A1 (en)
FR (1) FR2182943A1 (en)
NL (1) NL7304882A (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5171994A (en) * 1974-12-17 1976-06-22 Nippon Electric Co
US4645661A (en) * 1984-06-29 1987-02-24 St. Jude Children's Research Hospital Method for alleviating cisplatin-induced nephrotoxicity and dithiocarbamate compounds for effecting same
TWI315982B (en) 2001-07-19 2009-10-21 Novartis Ag Combinations comprising epothilones and pharmaceutical uses thereof
US7122668B2 (en) * 2001-08-23 2006-10-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Platinum complexes and their use in therapy
EP2272511A1 (en) 2006-05-09 2011-01-12 Novartis AG Combination comprising an iron chelator and an anti-neoplastic agent and use thereof
EP2444912A3 (en) * 2006-06-28 2012-07-25 IHI Corporation Magnetic drug, magnetic drug guidance system and magnetic drug design method
NZ586053A (en) 2007-11-09 2012-09-28 Peregrine Pharmaceuticals Inc Anti-vegf antibody compositions and methods
US20090169484A1 (en) 2007-12-28 2009-07-02 Ihi Corporation Iron-salen complex
RU2495045C2 (en) 2008-11-20 2013-10-10 АйЭйчАй КОРПОРЕЙШН Complex compound of magnetisable metal and salen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS", VOLUME 78, REF. 79753Q 1973 ) *

Also Published As

Publication number Publication date
JPS4913316A (en) 1974-02-05
NL7304882A (en) 1973-10-12
FR2182943B1 (en) 1976-12-31
DE2318020A1 (en) 1973-11-08

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Legal Events

Date Code Title Description
ST Notification of lapse