NL301065I1 - - Google Patents
Info
- Publication number
- NL301065I1 NL301065I1 NL301065C NL301065C NL301065I1 NL 301065 I1 NL301065 I1 NL 301065I1 NL 301065 C NL301065 C NL 301065C NL 301065 C NL301065 C NL 301065C NL 301065 I1 NL301065 I1 NL 301065I1
- Authority
- NL
- Netherlands
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12760308P | 2008-05-14 | 2008-05-14 | |
PCT/US2009/003014 WO2009151529A1 (en) | 2008-05-14 | 2009-05-14 | Novel modulators of sphingosine phosphate receptors |
US12/465,767 US8796318B2 (en) | 2008-05-14 | 2009-05-14 | Modulators of sphingosine phosphate receptors |
Publications (2)
Publication Number | Publication Date |
---|---|
NL301065I1 true NL301065I1 (nl) | 2020-09-30 |
NL301065I2 NL301065I2 (nl) | 2020-10-28 |
Family
ID=41416994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL301065C NL301065I2 (nl) | 2008-05-14 | 2020-09-30 | Ozanimod of een farmaceutisch aanvaardbaar zout daarvan, in het bijzonder ozanimodhydrochloride |
Country Status (20)
Country | Link |
---|---|
US (8) | US8796318B2 (nl) |
EP (3) | EP2913326B1 (nl) |
JP (2) | JP5837417B2 (nl) |
AU (2) | AU2009258242B2 (nl) |
CY (2) | CY1123338T1 (nl) |
DK (1) | DK2291080T3 (nl) |
EA (1) | EA021672B1 (nl) |
ES (2) | ES2813368T3 (nl) |
FI (2) | FI2291080T5 (nl) |
HR (1) | HRP20150982T1 (nl) |
HU (2) | HUE025984T2 (nl) |
LT (1) | LTC2291080I2 (nl) |
MY (2) | MY172105A (nl) |
NL (1) | NL301065I2 (nl) |
NO (1) | NO2020034I1 (nl) |
NZ (1) | NZ589617A (nl) |
PL (2) | PL2291080T3 (nl) |
PT (2) | PT2291080E (nl) |
SI (1) | SI2291080T1 (nl) |
WO (1) | WO2009151529A1 (nl) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
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TWI392671B (zh) | 2006-09-07 | 2013-04-11 | Actelion Pharmaceuticals Ltd | 吡啶-4-基衍生物 |
DK2125797T3 (da) | 2007-03-16 | 2014-02-10 | Actelion Pharmaceuticals Ltd | Aminopyridinderivater som s1p1/edg1-receptoragonister |
WO2009024905A1 (en) | 2007-08-17 | 2009-02-26 | Actelion Pharmaceuticals Ltd | Pyridine derivatives as s1p1/edg1 receptor modulators |
AU2008320374A1 (en) | 2007-11-01 | 2009-05-07 | Actelion Pharmaceuticals Ltd | Novel pyrimidine derivatives |
WO2009074950A2 (en) | 2007-12-10 | 2009-06-18 | Actelion Pharmaceuticals Ltd | Thiophene derivatives as agonists of s1p1/edg1 |
EP2262782B1 (en) | 2008-03-07 | 2012-07-04 | Actelion Pharmaceuticals Ltd. | Novel aminomethyl benzene derivatives |
PT2291080E (pt) | 2008-05-14 | 2015-10-30 | Scripps Research Inst | Novos modelamodeladores dos recetores da esfingosina fosfato |
RU2531915C2 (ru) | 2008-06-09 | 2014-10-27 | Людвиг-Максимилианс-Универзитет Мюнхен | Новые лекарственные средства для ингибирования агрегации белков, вовлеченных в заболевания, связанные с агрегацией белков, и нейродегенеративные заболевания |
EP2297139A1 (en) * | 2008-06-20 | 2011-03-23 | Glaxo Group Limited | Compounds |
KR20190004843A (ko) | 2008-07-23 | 2019-01-14 | 아레나 파마슈티칼스, 인크. | 자가면역성 및 염증성의 장애의 치료에 유용한 치환된 1,2,3,4-테트라히드로시클로펜타[b]인돌-3-일)아세트산 유도체 |
BRPI0917923B1 (pt) | 2008-08-27 | 2022-04-05 | Arena Pharmaceuticals Inc | Derivado de ácido tricíclico substituído, sua composição, seu uso e processo para preparar a referida composição |
ES2405054T3 (es) | 2009-01-23 | 2013-05-30 | Bristol-Myers Squibb Company | Derivados de pirazol-1,2,4-oxadiazol como agonistas de esfingosina-1-fosfato |
JP2012515788A (ja) | 2009-01-23 | 2012-07-12 | ブリストル−マイヤーズ スクイブ カンパニー | 自己免疫疾患および炎症性疾患の処置における、s1pアゴニストとしての置換オキサジアゾール誘導体 |
CN102361867A (zh) | 2009-01-23 | 2012-02-22 | 百时美施贵宝公司 | 在治疗自身免疫疾病和炎性疾病中作为s1p激动剂的取代的噁二唑衍生物 |
RU2547098C2 (ru) | 2009-07-16 | 2015-04-10 | Актелион Фармасьютиклз Лтд | Производные пиридин-4-ила |
US8399451B2 (en) | 2009-08-07 | 2013-03-19 | Bristol-Myers Squibb Company | Heterocyclic compounds |
BR112012011431A8 (pt) * | 2009-11-13 | 2017-12-26 | Receptos Llc | Moduladores heterocíclicos seletivos de receptor de esfingosina 1 fosfato |
EP2498611B1 (en) * | 2009-11-13 | 2018-01-10 | Celgene International II Sàrl | Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis |
AU2015202660B2 (en) * | 2009-11-13 | 2016-10-27 | Receptos Llc | Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis |
CN102762100B (zh) * | 2009-11-13 | 2015-07-01 | 瑞塞普托斯公司 | 选择性的1-磷酸鞘氨醇受体调节剂及手性合成方法 |
EP3378854B1 (en) | 2010-01-27 | 2022-12-21 | Arena Pharmaceuticals, Inc. | Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof |
JP2013521301A (ja) | 2010-03-03 | 2013-06-10 | アリーナ ファーマシューティカルズ, インコーポレイテッド | S1p1受容体修飾物質およびその結晶形の調製のためのプロセス |
EP2390252A1 (en) * | 2010-05-19 | 2011-11-30 | Almirall, S.A. | New pyrazole derivatives |
CN103237795B (zh) * | 2010-09-24 | 2015-10-21 | 百时美施贵宝公司 | 经取代的噁二唑化合物及其作为s1p1激动剂的用途 |
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CN102718726A (zh) * | 2011-03-31 | 2012-10-10 | 上海铂力生物科技有限公司 | 作为免疫调节剂的(z)-5-苯亚甲基噻唑啉-4-酮衍生物 |
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US9199975B2 (en) | 2011-09-30 | 2015-12-01 | Asana Biosciences, Llc | Biaryl imidazole derivatives for regulating CYP17 |
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CN116850181A (zh) | 2015-01-06 | 2023-10-10 | 艾尼纳制药公司 | 治疗与s1p1受体有关的病症的方法 |
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HUE047646T2 (hu) | 2015-05-20 | 2020-05-28 | Idorsia Pharmaceuticals Ltd | Az (S)-3-{4-[5-(2-ciklopentil-6-metoxi-piridin-4-il)-[1,2,4]oxadiazol-3-il]-2-etil-6-metil-fenoxi} -propán-1,2-diol vegyület kristályformája |
MX2017016530A (es) | 2015-06-22 | 2018-03-12 | Arena Pharm Inc | Sal cristalina de l-arginina del acido (r)-2-(7-(4-ciclopentil-3-( trifluorometil)benciloxi)-1,2,3,4-tetrahidrociclopenta[b]indol-3- il)acetico (compuesto1) para ser utilizada en transtornos asociados con el receptor de esfingosina-1-fosfato 1 (s1p1). |
CN114957157A (zh) | 2016-06-14 | 2022-08-30 | 瑞塞普托斯有限责任公司 | 奥扎莫德盐酸盐的晶型及其制备方法 |
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WO2018136893A1 (en) | 2017-01-23 | 2018-07-26 | Naqi Logics, Llc | Apparatus, methods, and systems for using imagined direction to define actions, functions, or execution |
CN110520124A (zh) | 2017-02-16 | 2019-11-29 | 艾尼纳制药公司 | 用于治疗原发性胆汁性胆管炎的化合物和方法 |
US11478448B2 (en) | 2017-02-16 | 2022-10-25 | Arena Pharmaceuticals, Inc. | Compounds and methods for treatment of inflammatory bowel disease with extra-intestinal manifestations |
US10981900B2 (en) * | 2017-02-28 | 2021-04-20 | Medshine Discovery Inc. | Spiro compound and use thereof |
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WO2019094409A1 (en) | 2017-11-07 | 2019-05-16 | Teva Pharmaceuticals International Gmbh | Salts and solid state forms of ozanimod |
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AR116479A1 (es) | 2018-09-25 | 2021-05-12 | Quim Sintetica S A | Intermediarios para la síntesis de ozanimod y procedimiento para la preparación del mencionado agonista del receptor de esfingosina-1-fosfato y de dichos intermediarios |
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US20220227722A1 (en) * | 2019-04-26 | 2022-07-21 | Receptos Llc | Sphingosine 1 phosphate receptor modulator |
CN112062785B (zh) * | 2019-06-11 | 2023-06-27 | 广东东阳光药业有限公司 | 奥扎莫德及其中间体的制备方法 |
WO2021026479A1 (en) * | 2019-08-07 | 2021-02-11 | Stamford, Andrew | Small molecule inhibitors of s1p2 receptor and uses thereof |
JP2023508907A (ja) | 2019-12-20 | 2023-03-06 | テナヤ セラピューティクス, インコーポレイテッド | フルオロアルキル-オキサジアゾールおよびその使用 |
KR20220158743A (ko) * | 2020-03-27 | 2022-12-01 | 리셉토스 엘엘씨 | 스핑고신 1 포스페이트 수용체 조절제 |
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EP2099741A2 (en) | 2006-11-21 | 2009-09-16 | University Of Virginia Patent Foundation | Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity |
NZ577111A (en) | 2006-12-15 | 2012-05-25 | Abbott Lab | Novel oxadiazole compounds |
JO2701B1 (en) | 2006-12-21 | 2013-03-03 | جلاكسو جروب ليميتد | Vehicles |
US20090188269A1 (en) | 2008-01-25 | 2009-07-30 | Henkel Corporation | High pressure connection systems and methods for their manufacture |
HUE050411T2 (hu) | 2008-05-14 | 2020-12-28 | Scripps Research Inst | Szfingozin foszfát receptorok új modulátorai |
PT2291080E (pt) | 2008-05-14 | 2015-10-30 | Scripps Research Inst | Novos modelamodeladores dos recetores da esfingosina fosfato |
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2009
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- 2009-05-14 WO PCT/US2009/003014 patent/WO2009151529A1/en active Application Filing
- 2009-05-14 SI SI200931271T patent/SI2291080T1/sl unknown
- 2009-05-14 JP JP2011509488A patent/JP5837417B2/ja active Active
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- 2009-05-14 AU AU2009258242A patent/AU2009258242B2/en active Active
- 2009-05-14 ES ES15158887T patent/ES2813368T3/es active Active
- 2009-05-14 PT PT151588878T patent/PT2913326T/pt unknown
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- 2009-05-14 ES ES09762826.7T patent/ES2549761T3/es active Active
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- 2009-05-14 FI FIEP09762826.7T patent/FI2291080T5/fi active
- 2009-05-14 EP EP20185750.5A patent/EP3782991A1/en not_active Withdrawn
- 2009-05-14 EA EA201001785A patent/EA021672B1/ru unknown
- 2009-05-14 PL PL15158887T patent/PL2913326T3/pl unknown
- 2009-05-14 DK DK09762826.7T patent/DK2291080T3/en active
- 2009-05-14 EP EP09762826.7A patent/EP2291080B1/en active Active
- 2009-05-14 US US12/465,767 patent/US8796318B2/en active Active
- 2009-05-14 HU HUE09762826A patent/HUE025984T2/hu unknown
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2012
- 2012-09-06 US US13/605,561 patent/US8481573B2/en active Active
- 2012-09-06 US US13/605,358 patent/US8530503B2/en active Active
- 2012-09-06 US US13/605,427 patent/US8466183B2/en active Active
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2014
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2015
- 2015-08-12 AU AU2015213309A patent/AU2015213309B2/en active Active
- 2015-09-17 HR HRP20150982TT patent/HRP20150982T1/hr unknown
- 2015-11-05 JP JP2015217236A patent/JP2016041736A/ja active Pending
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2016
- 2016-06-21 US US15/188,132 patent/US20170050941A1/en not_active Abandoned
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2017
- 2017-09-22 US US15/713,237 patent/US9975863B2/en active Active
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2018
- 2018-04-23 US US15/959,935 patent/US10544136B2/en active Active
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2020
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- 2020-09-30 NL NL301065C patent/NL301065I2/nl unknown
- 2020-10-01 LT LTPA2020529C patent/LTC2291080I2/lt unknown
- 2020-10-01 HU HUS2000038C patent/HUS2000038I1/hu unknown
- 2020-10-02 CY CY2020033C patent/CY2020033I2/el unknown