NL300828I2 - albutrepenonacog alfa - Google Patents
albutrepenonacog alfaInfo
- Publication number
- NL300828I2 NL300828I2 NL300828C NL300828C NL300828I2 NL 300828 I2 NL300828 I2 NL 300828I2 NL 300828 C NL300828 C NL 300828C NL 300828 C NL300828 C NL 300828C NL 300828 I2 NL300828 I2 NL 300828I2
- Authority
- NL
- Netherlands
- Prior art keywords
- albutrepenonacog
- alfa
- albutrepenonacog alfa
- Prior art date
Links
- 229960001354 albutrepenonacog alfa Drugs 0.000 title 1
- 108010049769 albutrepenonacog alfa Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6472—Cysteine endopeptidases (3.4.22)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06012262A EP1867660A1 (en) | 2006-06-14 | 2006-06-14 | Proteolytically cleavable fusion protein comprising a blood coagulation factor |
US81962006P | 2006-07-11 | 2006-07-11 | |
PCT/EP2007/005246 WO2007144173A1 (en) | 2006-06-14 | 2007-06-14 | Proteolytically cleavable fusion protein comprising a blood coagulation factor |
EP07726010.7A EP2032607B2 (en) | 2006-06-14 | 2007-06-14 | Proteolytically cleavable fusion protein comprising a blood coagulation factor |
Publications (1)
Publication Number | Publication Date |
---|---|
NL300828I2 true NL300828I2 (nl) | 2024-09-18 |
Family
ID=38430551
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL300828C NL300828I2 (nl) | 2006-06-14 | 2016-09-09 | albutrepenonacog alfa |
Country Status (10)
Country | Link |
---|---|
EP (2) | EP2032607B2 (nl) |
JP (1) | JP5800458B2 (nl) |
KR (1) | KR101641899B1 (nl) |
AU (1) | AU2007260185B2 (nl) |
CA (1) | CA2655248C (nl) |
DK (2) | DK2256135T3 (nl) |
ES (2) | ES2910207T3 (nl) |
NL (1) | NL300828I2 (nl) |
PL (2) | PL3896090T3 (nl) |
WO (1) | WO2007144173A1 (nl) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
JP5832285B2 (ja) | 2008-06-24 | 2015-12-16 | ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー | 延長されたインビボ半減期を有する第viii因子、フォン・ヴィレブランド因子又はそれらの複合体 |
CN102317315A (zh) | 2009-02-11 | 2012-01-11 | 诺维信生物制药丹麦公司 | 白蛋白变体和缀合物 |
CA2770609A1 (en) | 2009-08-20 | 2011-02-24 | Csl Behring Gmbh | Albumin fused coagulation factors for non-intravenous administration in the therapy and prophylactic treatment of bleeding disorders |
JP5813641B2 (ja) | 2009-08-24 | 2015-11-17 | アムニクス オペレーティング インコーポレイテッド | 凝固第ix因子組成物ならびにそれを製造および使用する方法 |
EP2493921B1 (en) | 2009-10-30 | 2018-09-26 | Albumedix Ltd | Albumin variants |
ES2796829T3 (es) | 2009-12-18 | 2020-11-30 | Csl Ltd | Procedimiento de purificación de polipéptidos |
EP2371857A1 (en) | 2010-04-01 | 2011-10-05 | CSL Behring GmbH | Factor XII inhibitors for treating interstitial lung disease |
NZ605400A (en) * | 2010-07-09 | 2015-05-29 | Biogen Idec Hemophilia Inc | Chimeric clotting factors |
KR20180118808A (ko) | 2010-07-09 | 2018-10-31 | 바이오버라티브 테라퓨틱스 인크. | 인자 ix 폴리펩티드 및 이들의 사용 방법 |
JP6101638B2 (ja) | 2011-03-03 | 2017-03-22 | ザイムワークス,インコーポレイテッド | 多価ヘテロマルチマー足場設計及び構築物 |
JP6108630B2 (ja) | 2011-10-06 | 2017-04-05 | ハンミ サイエンス カンパニー リミテッドHanmi Science Co.,Ltd. | 血液凝固因子VII及びVIIa誘導体、それらを含む結合体及び複合体、並びにそれらの使用 |
US20140315817A1 (en) | 2011-11-18 | 2014-10-23 | Eleven Biotherapeutics, Inc. | Variant serum albumin with improved half-life and other properties |
PL2804623T3 (pl) | 2012-01-12 | 2020-03-31 | Bioverativ Therapeutics Inc. | Chimeryczne polipeptydy czynnika viii i ich zastosowania |
MY188897A (en) | 2012-02-15 | 2022-01-12 | Bioverativ Therapeutics Inc | Factor viii compositions and methods of making and using same |
BR112014019901A8 (pt) | 2012-02-15 | 2018-01-02 | Biogen Idec Inc | Proteínas de fator viii recombinante |
PL2814502T3 (pl) | 2012-02-15 | 2018-02-28 | Csl Behring Gmbh | Warianty czynnika von Willebranda mające ulepszone powinowactwo do wiązania czynnika VIII |
KR20140136934A (ko) | 2012-03-16 | 2014-12-01 | 노보자임스 바이오파마 디케이 에이/에스 | 알부민 변이체 |
BR112015000267B1 (pt) | 2012-07-11 | 2023-01-24 | Bioverativ Therapeutics Inc. | Proteínas quiméricas, e composição farmacêutica |
WO2014012082A2 (en) | 2012-07-13 | 2014-01-16 | Zymeworks Inc. | Multivalent heteromultimer scaffold design an constructs |
TWI750197B (zh) | 2012-09-25 | 2021-12-21 | 美商百歐維拉提夫治療公司 | Fix多肽的應用 |
AU2013343503B2 (en) | 2012-11-08 | 2017-12-14 | Albumedix Ltd. | Albumin variants |
KR20150118123A (ko) | 2013-02-16 | 2015-10-21 | 노보자임스 바이오파마 디케이 에이/에스 | 약동학적 동물 모델 |
EP2968498A4 (en) | 2013-03-15 | 2016-09-07 | Biogen Ma Inc | PREPARATIONS CONTAINING FACTOR IX POLYPEPTIDE |
EP2796145B1 (en) | 2013-04-22 | 2017-11-01 | CSL Ltd. | A covalent complex of von willebrand factor and faktor viii linked by a disulphide bridge |
EP3013359A4 (en) * | 2013-06-28 | 2017-01-25 | Biogen MA Inc. | Thrombin cleavable linker |
EP3033097B1 (en) | 2013-08-14 | 2021-03-10 | Bioverativ Therapeutics Inc. | Factor viii-xten fusions and uses thereof |
SI4176894T1 (sl) | 2014-01-10 | 2024-07-31 | Bioverativ Therapeutics Inc. | Himerni proteini faktorja VIII in njihova uporaba |
US10253088B2 (en) | 2014-07-02 | 2019-04-09 | CSL Behring Lengnau AG | Modified von Willebrand Factor |
SG10201910896UA (en) | 2015-05-22 | 2020-01-30 | CSL Behring Lengnau AG | Truncated von willebrand factor polypeptides for treating hemophilia |
JP6651548B2 (ja) | 2015-05-22 | 2020-02-19 | ツェー・エス・エル・ベーリング・レングナウ・アクチエンゲゼルシャフト | 改変フォン・ヴィルブランド因子を製造するための方法 |
TWI741992B (zh) | 2015-08-03 | 2021-10-11 | 美商百歐維拉提夫治療公司 | 因子ix融合蛋白以及其製備及使用方法 |
AU2016308504A1 (en) | 2015-08-20 | 2018-01-18 | Albumedix Ltd. | Albumin variants and conjugates |
WO2017066653A1 (en) * | 2015-10-15 | 2017-04-20 | Woods Hole Oceanographic Institution | Compositions and methods for absolute quantification of proteins |
US10806774B2 (en) | 2016-01-07 | 2020-10-20 | CSL Behring Lengnau AG | Mutated truncated von Willebrand Factor |
ES2881701T3 (es) | 2016-01-07 | 2021-11-30 | CSL Behring Lengnau AG | Factor de von Willebrand mutado |
DK3538134T3 (da) | 2016-11-11 | 2022-02-07 | CSL Behring Lengnau AG | Trunkeret von willebrand-faktor polypeptider til ekstravaskulær administration til behandling eller profylakse af en blodkoagulationsforstyrrelse |
AU2017358861B2 (en) | 2016-11-11 | 2022-02-17 | CSL Behring Lengnau AG | Truncated von Willebrand Factor polypeptides for treating hemophilia |
WO2018206168A1 (en) * | 2017-05-11 | 2018-11-15 | Zentrum Für Forschungsförderung In Der Pädiatrie Gmbh | Concept for the treatment of monogenetic disorders |
EP3687580A1 (en) | 2017-09-27 | 2020-08-05 | Sigilon Therapeutics, Inc. | Methods, compositions, and implantable elements comprising active cells |
US20210145889A1 (en) | 2018-04-04 | 2021-05-20 | Sigilon Therapeutics, Inc. | Methods, compositions, and implantable elements comprising stem cells |
WO2019195055A1 (en) | 2018-04-04 | 2019-10-10 | Sigilon Therapeutics, Inc. | Implantable particles and related methods |
KR20210020030A (ko) | 2018-05-18 | 2021-02-23 | 바이오버라티브 테라퓨틱스 인크. | A형 혈우병의 치료 방법 |
UY38389A (es) | 2018-09-27 | 2020-04-30 | Sigilon Therapeutics Inc | Dispositivos implantables para terapia celular y métodos relacionados |
US20220154161A1 (en) | 2019-03-19 | 2022-05-19 | CSL Behring Lengnau AG | Factor ix variants and uses thereof in therapy |
KR20220029733A (ko) | 2019-07-04 | 2022-03-08 | 체에스엘 베링 렝나우 아게 | 응고 인자 viii의 시험관내 안정성을 증가시키기 위한 절단된 폰 빌레브란트 인자 (vwf) |
WO2024081309A1 (en) | 2022-10-11 | 2024-04-18 | Sigilon Therapeutics, Inc. | Engineered cells and implantable elements for treatment of disease |
WO2024081310A1 (en) | 2022-10-11 | 2024-04-18 | Sigilon Therapeutics, Inc. | Engineered cells and implantable elements for treatment of disease |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR860984B (en) | 1985-04-17 | 1986-08-18 | Zymogenetics Inc | Expression of factor vii and ix activities in mammalian cells |
GB8927722D0 (en) | 1989-12-07 | 1990-02-07 | British Bio Technology | Proteins and nucleic acids |
ES2153483T3 (es) * | 1994-07-11 | 2001-03-01 | Univ Texas | Metodos y composiciones para la coagulacion especifica en los vasos tumorales. |
CA2405525A1 (en) * | 2000-04-12 | 2001-10-25 | Principia Pharmaceutical Corporation | Albumin fusion proteins |
AU2001275897A1 (en) | 2000-07-12 | 2002-01-21 | Immunex Corporation | Improvement of cell culture performance |
ATE425989T1 (de) | 2001-12-21 | 2009-04-15 | Immunex Corp | Proteinreinigungsverfahren |
CA2475388A1 (en) | 2002-02-14 | 2003-08-21 | William J. Rutter | Chimeric molecules for cleavage in a treated host |
WO2004021861A2 (en) * | 2002-09-03 | 2004-03-18 | Vit Lauermann | Targeted release |
EP1444986A1 (en) * | 2003-02-07 | 2004-08-11 | Aventis Behring GmbH | Pharmaceutical preparation for the improved treatment of blood-clotting disorders |
US20050176108A1 (en) | 2003-03-13 | 2005-08-11 | Young-Min Kim | Physiologically active polypeptide conjugate having prolonged in vivo half-life |
EP3552627A1 (en) | 2003-05-06 | 2019-10-16 | Bioverativ Therapeutics Inc. | Clotting factor-fc chimeric proteins to treat hemophilia |
TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
WO2005024044A2 (en) | 2003-09-05 | 2005-03-17 | Gtc Biotherapeutics, Inc. | Method for the production of fusion proteins in transgenic mammal milk |
EP1816201A1 (en) * | 2006-02-06 | 2007-08-08 | CSL Behring GmbH | Modified coagulation factor VIIa with extended half-life |
-
2007
- 2007-06-14 WO PCT/EP2007/005246 patent/WO2007144173A1/en active Application Filing
- 2007-06-14 EP EP07726010.7A patent/EP2032607B2/en active Active
- 2007-06-14 AU AU2007260185A patent/AU2007260185B2/en active Active
- 2007-06-14 DK DK10168453.8T patent/DK2256135T3/da active
- 2007-06-14 KR KR1020097000784A patent/KR101641899B1/ko active IP Right Grant
- 2007-06-14 JP JP2009514703A patent/JP5800458B2/ja active Active
- 2007-06-14 PL PL21162926T patent/PL3896090T3/pl unknown
- 2007-06-14 ES ES21162926T patent/ES2910207T3/es active Active
- 2007-06-14 CA CA2655248A patent/CA2655248C/en active Active
- 2007-06-14 PL PL07726010T patent/PL2032607T5/pl unknown
- 2007-06-14 DK DK21162926.6T patent/DK3896090T3/da active
- 2007-06-14 EP EP21162926.6A patent/EP3896090B1/en active Active
- 2007-06-14 ES ES19162362T patent/ES2889920T3/es active Active
-
2016
- 2016-09-09 NL NL300828C patent/NL300828I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
EP3896090B1 (en) | 2022-01-12 |
DK3896090T3 (da) | 2022-03-21 |
JP5800458B2 (ja) | 2015-10-28 |
AU2007260185A1 (en) | 2007-12-21 |
EP2032607B1 (en) | 2014-01-22 |
KR20090023486A (ko) | 2009-03-04 |
PL3896090T3 (pl) | 2022-05-02 |
PL2032607T5 (pl) | 2017-10-31 |
JP2009539391A (ja) | 2009-11-19 |
DK2256135T3 (da) | 2019-06-11 |
EP2032607B2 (en) | 2017-02-22 |
ES2889920T3 (es) | 2022-01-14 |
WO2007144173A1 (en) | 2007-12-21 |
AU2007260185B2 (en) | 2013-01-31 |
ES2910207T3 (es) | 2022-05-11 |
KR101641899B1 (ko) | 2016-08-01 |
PL2032607T3 (pl) | 2014-06-30 |
CA2655248A1 (en) | 2007-12-21 |
EP2032607A1 (en) | 2009-03-11 |
CA2655248C (en) | 2016-02-09 |
EP3896090A1 (en) | 2021-10-20 |
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