NL2025294B1 - Antimicrobial peptide for treatment and controlling virus infections - Google Patents

Antimicrobial peptide for treatment and controlling virus infections Download PDF

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Publication number
NL2025294B1
NL2025294B1 NL2025294A NL2025294A NL2025294B1 NL 2025294 B1 NL2025294 B1 NL 2025294B1 NL 2025294 A NL2025294 A NL 2025294A NL 2025294 A NL2025294 A NL 2025294A NL 2025294 B1 NL2025294 B1 NL 2025294B1
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NL
Netherlands
Prior art keywords
seq
antimicrobial peptide
peptide
virus
amino acid
Prior art date
Application number
NL2025294A
Other languages
English (en)
Inventor
Broertjes Paul
Peter Johannes Maria Brouwer Cornelis
Original Assignee
Cbmr Scient Nanoscience B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cbmr Scient Nanoscience B V filed Critical Cbmr Scient Nanoscience B V
Priority to NL2025294A priority Critical patent/NL2025294B1/en
Priority to NL2027924A priority patent/NL2027924B1/en
Priority to PCT/NL2021/050224 priority patent/WO2021206548A1/en
Application granted granted Critical
Publication of NL2025294B1 publication Critical patent/NL2025294B1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40Transferrins, e.g. lactoferrins, ovotransferrins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79Transferrins, e.g. lactoferrins, ovotransferrins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Claims (3)

  1. CONCLUSIES: I. Antimicrobieel peptide voor gebruik in een methode voor het voorkomen of behandelen en / of beheersen van een virusinfectie bij een mens of dier, waarbij het antimicrobiële peptide een van de volgende aminozuursequenties omvat of daaruit bestaat: RRRRSVQWCA [SEQ ID NO: 1], GRRRRSVQWCA [SEQ ID NO: 3}, ACWQVSRRRR [SEQ ID NO: 2], ACWQVSRRRRG [SEQ ID NO: 4}, CGRRRRSVQWCA [SEQ ID NO: 5], of een functionele mutant daarvan,
  2. 2. Samenstelling omvattende een antimicrobieel peptide en een farmaceutisch aanvaardbaar verdunningsmiddel of excipiëns, voor gebruik in een methode voor het voorkomen of behandelen en / of beheersen van een virusinfectie bij een mens of dier, waarbij het antimicrobiële peptide een van de volgende aminozuursequenties omvat of daaruit bestaat: RRRRSVQWCA {SEQ ID NO: 1], GRRRRSVQWCA [SEQ ID NO: 3], ACWQVSRRRR {SEQ ID NO: 2], ACWQVSRRRRG [SEQ ID NO: 4], CGRRRRSVQWCA [SEQ ID NO: 5], of een functionele mutant daarvan.
  3. 3. Werkwijze voor het behandelen van een patiënt die aan virusinfecties lijdt, waarbij de methode omvat het toedienen van een therapeutisch effectieve hoeveelheid van een antimicrobieel peptide aan patiënten die zijn aangetast door virusinfecties, waarbij het antimicrobiële peptide een van de aminozuursequenties omvat of hieruit bestaat: RRRRSVQWCA [SEQ ID] NO: 1], GRRRRSVQWCA [SEQ ID NO: 3], ACWQVSRRRR [SEQ ID NO: 2}, ACWQVSRRRRG {SEQ ID NO: 4}, CGRRRRSVQWCA [SEQ ID NO: 5}, of een functionele mutant daarvan.
NL2025294A 2020-04-07 2020-04-07 Antimicrobial peptide for treatment and controlling virus infections NL2025294B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
NL2025294A NL2025294B1 (en) 2020-04-07 2020-04-07 Antimicrobial peptide for treatment and controlling virus infections
NL2027924A NL2027924B1 (en) 2020-04-07 2021-04-06 Antimicrobial peptide for prevention and treatment of virusinfections
PCT/NL2021/050224 WO2021206548A1 (en) 2020-04-07 2021-04-06 Antimicrobial peptide for treatment and controlling virus infections

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL2025294A NL2025294B1 (en) 2020-04-07 2020-04-07 Antimicrobial peptide for treatment and controlling virus infections

Publications (1)

Publication Number Publication Date
NL2025294B1 true NL2025294B1 (en) 2021-10-25

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
NL2025294A NL2025294B1 (en) 2020-04-07 2020-04-07 Antimicrobial peptide for treatment and controlling virus infections
NL2027924A NL2027924B1 (en) 2020-04-07 2021-04-06 Antimicrobial peptide for prevention and treatment of virusinfections

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL2027924A NL2027924B1 (en) 2020-04-07 2021-04-06 Antimicrobial peptide for prevention and treatment of virusinfections

Country Status (2)

Country Link
NL (2) NL2025294B1 (nl)
WO (1) WO2021206548A1 (nl)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0769915A (ja) * 1993-09-02 1995-03-14 Snow Brand Milk Prod Co Ltd ウィルス感染・増殖抑制剤
EP2030980A1 (en) * 2007-08-28 2009-03-04 AM-Pharma B.V. Mutants of lactoferrin
US20090142298A1 (en) * 2007-09-05 2009-06-04 Shatunovskiy Nikolay E Apolactoferrin Compositions and Methods for Their Use in the Treatment of Viral Hepatitis C

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0769915A (ja) * 1993-09-02 1995-03-14 Snow Brand Milk Prod Co Ltd ウィルス感染・増殖抑制剤
EP2030980A1 (en) * 2007-08-28 2009-03-04 AM-Pharma B.V. Mutants of lactoferrin
WO2009028943A1 (en) 2007-08-28 2009-03-05 Am-Pharma B.V. Mutants of lactoferrin
US20090142298A1 (en) * 2007-09-05 2009-06-04 Shatunovskiy Nikolay E Apolactoferrin Compositions and Methods for Their Use in the Treatment of Viral Hepatitis C

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ALLAIRE ANDRÉA ET AL: "Immunofluorescence to Monitor the Cellular Uptake of Human Lactoferrin and its Associated Antiviral Activity Against the Hepatitis C Virus", JOURNAL OF VISUALIZED EXPERIMENTS, no. 104, 1 January 2015 (2015-01-01), XP055781354, DOI: 10.3791/53053 *
JENSSEN H ET AL: "Antimicrobial properties of lactoferrin", BIOCHIMIE, MASSON, PARIS, FR, vol. 91, no. 1, 1 January 2009 (2009-01-01), pages 19 - 29, XP025869223, ISSN: 0300-9084, [retrieved on 20080605], DOI: 10.1016/J.BIOCHI.2008.05.015 *
JENSSEN H: "Anti herpes simplex virus activity of lactoferrin/lactoferricin - an example of antiviral activity of antimicrobial protein/peptide", CELLULAR AND MOLECULAR LIFE SCIENCES, BIRKHÄUSER-VERLAG, BA, vol. 62, no. 24, 1 December 2005 (2005-12-01), pages 3002 - 3013, XP019200911, ISSN: 1420-9071, DOI: 10.1007/S00018-005-5228-7 *

Also Published As

Publication number Publication date
NL2027924A (en) 2021-10-25
NL2027924B1 (en) 2022-03-11
WO2021206548A1 (en) 2021-10-14

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Effective date: 20230501