NL191314C - 3-Monogesubstitueerd-1-azetidine-carboxamidederivaat, alsmede een anticonvulsief preparaat. - Google Patents
3-Monogesubstitueerd-1-azetidine-carboxamidederivaat, alsmede een anticonvulsief preparaat.Info
- Publication number
- NL191314C NL191314C NL8005514A NL8005514A NL191314C NL 191314 C NL191314 C NL 191314C NL 8005514 A NL8005514 A NL 8005514A NL 8005514 A NL8005514 A NL 8005514A NL 191314 C NL191314 C NL 191314C
- Authority
- NL
- Netherlands
- Prior art keywords
- anticonvulsant
- monosubstituted
- preparation
- well
- carboxamide derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/029,800 US4226861A (en) | 1978-04-18 | 1979-04-13 | N-Lower-alkyl 3-phenoxy-1-azetidinecarboxamides |
CH740880A CH645352A5 (en) | 1978-04-18 | 1980-10-03 | N-Lower alkyl-3-phenoxy-1-azetidinecarboxamides |
GB8032104A GB2084993B (en) | 1978-04-18 | 1980-10-06 | N-lower-alkyl 3-phenoxy-1-azetidine-carboxamides |
CA000361594A CA1161853A (en) | 1978-04-18 | 1980-10-06 | N-lower-alkyl 3-phenoxy-1-azetidine-carboxamides |
DE3037770A DE3037770C2 (de) | 1978-04-18 | 1980-10-06 | N-Niedrigalkyl-3-phenoxy-1-azetidincarboxamide und diese Verbindungen enthaltende Zubereitungen |
BE0/202346A BE885549A (fr) | 1978-04-18 | 1980-10-06 | N-alkyl inferieur-3-phenoxy-1-azetidine-carboxamides |
JP55139734A JPS5764665A (en) | 1978-04-18 | 1980-10-06 | N-lower alkyl 3-phenoxy-1-azetidine carboxamides |
FR8021340A FR2491467A1 (fr) | 1978-04-18 | 1980-10-06 | Nouveaux n-alkyl inferieur)-3-phenoxy-1-azetidinecarboxamides possedant notamment une activite sur le systeme nerveux central, et leur procede de preparation |
NL8005514A NL191314C (nl) | 1978-04-18 | 1980-10-06 | 3-Monogesubstitueerd-1-azetidine-carboxamidederivaat, alsmede een anticonvulsief preparaat. |
AU32252/84A AU571258B2 (en) | 1978-04-18 | 1984-08-21 | N-lower alkyl-3-phenoxy-1-azetidinecarboxamides |
Applications Claiming Priority (20)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89746278A | 1978-04-18 | 1978-04-18 | |
US89746278 | 1978-04-18 | ||
US2980079 | 1979-04-13 | ||
US06/029,800 US4226861A (en) | 1978-04-18 | 1979-04-13 | N-Lower-alkyl 3-phenoxy-1-azetidinecarboxamides |
CH740880 | 1980-10-03 | ||
CH740880A CH645352A5 (en) | 1978-04-18 | 1980-10-03 | N-Lower alkyl-3-phenoxy-1-azetidinecarboxamides |
GB8032104 | 1980-10-06 | ||
JP13973480 | 1980-10-06 | ||
FR8021340A FR2491467A1 (fr) | 1978-04-18 | 1980-10-06 | Nouveaux n-alkyl inferieur)-3-phenoxy-1-azetidinecarboxamides possedant notamment une activite sur le systeme nerveux central, et leur procede de preparation |
DE3037770A DE3037770C2 (de) | 1978-04-18 | 1980-10-06 | N-Niedrigalkyl-3-phenoxy-1-azetidincarboxamide und diese Verbindungen enthaltende Zubereitungen |
DE3037770 | 1980-10-06 | ||
FR8021340 | 1980-10-06 | ||
NL8005514 | 1980-10-06 | ||
CA000361594A CA1161853A (en) | 1978-04-18 | 1980-10-06 | N-lower-alkyl 3-phenoxy-1-azetidine-carboxamides |
JP55139734A JPS5764665A (en) | 1978-04-18 | 1980-10-06 | N-lower alkyl 3-phenoxy-1-azetidine carboxamides |
NL8005514A NL191314C (nl) | 1978-04-18 | 1980-10-06 | 3-Monogesubstitueerd-1-azetidine-carboxamidederivaat, alsmede een anticonvulsief preparaat. |
GB8032104A GB2084993B (en) | 1978-04-18 | 1980-10-06 | N-lower-alkyl 3-phenoxy-1-azetidine-carboxamides |
CA361594 | 1980-10-06 | ||
AU3225284 | 1984-08-21 | ||
AU32252/84A AU571258B2 (en) | 1978-04-18 | 1984-08-21 | N-lower alkyl-3-phenoxy-1-azetidinecarboxamides |
Publications (3)
Publication Number | Publication Date |
---|---|
NL8005514A NL8005514A (nl) | 1982-05-03 |
NL191314B NL191314B (de) | 1994-12-16 |
NL191314C true NL191314C (nl) | 1995-05-16 |
Family
ID=27578959
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL8005514A NL191314C (nl) | 1978-04-18 | 1980-10-06 | 3-Monogesubstitueerd-1-azetidine-carboxamidederivaat, alsmede een anticonvulsief preparaat. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4226861A (de) |
JP (1) | JPS5764665A (de) |
BE (1) | BE885549A (de) |
CA (1) | CA1161853A (de) |
CH (1) | CH645352A5 (de) |
DE (1) | DE3037770C2 (de) |
FR (1) | FR2491467A1 (de) |
GB (1) | GB2084993B (de) |
NL (1) | NL191314C (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4379151A (en) * | 1978-03-14 | 1983-04-05 | A. H. Robins Company, Inc. | 3-Phenoxyazetidines for anorexigenic activity |
IL68699A (en) * | 1982-08-19 | 1986-08-31 | Robins Co Inc A H | 3-phenoxy-1-azetidine-carboxamides,their preparation and pharmaceutical compositions containing them |
US4571393A (en) * | 1982-08-19 | 1986-02-18 | A. H. Robins Company, Incorporated | 3-Phenoxy-1-azetidinecarboxamides |
US4505907A (en) * | 1982-09-02 | 1985-03-19 | A. H. Robins Company, Inc. | N-Formyl and N-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides |
US4594189A (en) * | 1983-07-06 | 1986-06-10 | A. H. Robins Company, Inc. | Process for preparing 3-phenoxy-1-azetidines and carboxamide derivatives |
IN162808B (de) * | 1985-02-28 | 1988-07-09 | Robins Co Inc A H | |
IE58943B1 (en) * | 1985-02-28 | 1993-12-01 | Robins Co Inc A H | 3-Aryloxy-azetidine-carboxamides |
US5068231A (en) * | 1985-02-28 | 1991-11-26 | A. H. Robins Company Incorporated | Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides |
US4956359A (en) * | 1985-02-28 | 1990-09-11 | A. H. Robins Company, Inc. | 3-aryloxy and 3-arylthioazetidinecarboxamides as anticonvulsants and antiepileptics |
ZA861210B (en) * | 1985-02-28 | 1987-10-28 | Robins Co Inc A H | 3-aryloxyazetidinecarboxamides as anticonvulsants and antiepileptics |
US5183902A (en) * | 1985-02-28 | 1993-02-02 | A. H. Robins Company, Incorporated | Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides |
US5151418A (en) * | 1985-02-28 | 1992-09-29 | A. H. Robins Company, Incorporated | Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides |
US5095014A (en) * | 1990-12-07 | 1992-03-10 | A. H. Robins Company, Incorporated | 3-(2-chloro-4-(trifluoromethyl)phenoxy)-1-azetidine carboxamides having anticonvulsant activity |
US5130309A (en) * | 1991-04-12 | 1992-07-14 | A. H. Robins Company, Incorporated | Aryloxy and aryloxyalklazetidines as antiarrhythmic and anticonvulsant agents |
US5183903A (en) * | 1991-11-26 | 1993-02-02 | A. H. Robins Company, Incorporated | Urea fusion process for the synthesis of 3-phenoxy-1-azetidinecarboxamides |
US6831078B1 (en) | 1998-01-23 | 2004-12-14 | Vernalis Research Limited | Azetidinecarboxamide derivatives for treating CNS disorders |
DK1049672T3 (da) | 1998-01-23 | 2004-01-19 | Vernalis Res Ltd | Azetidincarboxamid-derivater til behandling af CNS-lidelser |
GB9801501D0 (en) | 1998-01-23 | 1998-03-18 | Cerebrus Ltd | Chemical compounds - II |
GB9917386D0 (en) * | 1999-07-23 | 1999-09-22 | Cerebrus Ltd | Chemical compounds-II |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1332510A (fr) * | 1959-12-07 | 1963-07-19 | Lepetit Spa | Procédé pour la préparation de nouvelles carbamylazétidines |
DE1147585B (de) * | 1958-12-23 | 1963-04-25 | Lepetit Spa | Verfahren zur Herstellung von 1-Carbamylazetidinen (1-Carbamyl-trimethyleniminen) |
DE2053333A1 (de) * | 1970-10-30 | 1972-05-04 | Farbenfabriken Bayer Ag, 5090 Lever Kusen | Herbizide Mittel |
US4031221A (en) * | 1974-06-17 | 1977-06-21 | American Hoechst Corporation | Method of treating pain and hypertension |
US4379151A (en) * | 1978-03-14 | 1983-04-05 | A. H. Robins Company, Inc. | 3-Phenoxyazetidines for anorexigenic activity |
-
1979
- 1979-04-13 US US06/029,800 patent/US4226861A/en not_active Expired - Lifetime
-
1980
- 1980-10-03 CH CH740880A patent/CH645352A5/de not_active IP Right Cessation
- 1980-10-06 CA CA000361594A patent/CA1161853A/en not_active Expired
- 1980-10-06 NL NL8005514A patent/NL191314C/xx not_active IP Right Cessation
- 1980-10-06 BE BE0/202346A patent/BE885549A/fr not_active IP Right Cessation
- 1980-10-06 FR FR8021340A patent/FR2491467A1/fr active Granted
- 1980-10-06 JP JP55139734A patent/JPS5764665A/ja active Granted
- 1980-10-06 GB GB8032104A patent/GB2084993B/en not_active Expired
- 1980-10-06 DE DE3037770A patent/DE3037770C2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE3037770A1 (de) | 1982-05-19 |
GB2084993B (en) | 1984-07-11 |
CA1161853A (en) | 1984-02-07 |
JPS643185B2 (de) | 1989-01-19 |
NL191314B (de) | 1994-12-16 |
BE885549A (fr) | 1981-02-02 |
GB2084993A (en) | 1982-04-21 |
CH645352A5 (en) | 1984-09-28 |
DE3037770C2 (de) | 1994-11-10 |
NL8005514A (nl) | 1982-05-03 |
US4226861A (en) | 1980-10-07 |
JPS5764665A (en) | 1982-04-19 |
FR2491467B1 (de) | 1984-06-08 |
FR2491467A1 (fr) | 1982-04-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A85 | Still pending on 85-01-01 | ||
BA | A request for search or an international-type search has been filed | ||
BB | A search report has been drawn up | ||
BC | A request for examination has been filed | ||
CNR | Transfer of rights (patent application after its laying open for public inspection) |
Free format text: AHP SUBSIDIARY (9) CORPORATION |
|
DNT | Communications of changes of names of applicants whose applications have been laid open to public inspection |
Free format text: ROBINS COMPANY, INCORPORATED. A.H. - |
|
V1 | Lapsed because of non-payment of the annual fee |
Effective date: 19960501 |