JPS5764665A - N-lower alkyl 3-phenoxy-1-azetidine carboxamides - Google Patents

N-lower alkyl 3-phenoxy-1-azetidine carboxamides

Info

Publication number
JPS5764665A
JPS5764665A JP55139734A JP13973480A JPS5764665A JP S5764665 A JPS5764665 A JP S5764665A JP 55139734 A JP55139734 A JP 55139734A JP 13973480 A JP13973480 A JP 13973480A JP S5764665 A JPS5764665 A JP S5764665A
Authority
JP
Japan
Prior art keywords
phenoxy
lower alkyl
carboxamides
azetidine
azetidine carboxamides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP55139734A
Other languages
English (en)
Other versions
JPS643185B2 (ja
Inventor
Dankan Keeru Jiyuniaa Arubaato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US06/029,800 priority Critical patent/US4226861A/en
Priority to CH740880A priority patent/CH645352A5/de
Priority to NL8005514A priority patent/NL191314C/xx
Priority to FR8021340A priority patent/FR2491467A1/fr
Priority to BE0/202346A priority patent/BE885549A/fr
Priority to JP55139734A priority patent/JPS5764665A/ja
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Priority to GB8032104A priority patent/GB2084993B/en
Priority to DE3037770A priority patent/DE3037770C2/de
Priority to CA000361594A priority patent/CA1161853A/en
Publication of JPS5764665A publication Critical patent/JPS5764665A/ja
Priority to AU32252/84A priority patent/AU571258B2/en
Priority claimed from AU32252/84A external-priority patent/AU571258B2/en
Publication of JPS643185B2 publication Critical patent/JPS643185B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP55139734A 1978-04-18 1980-10-06 N-lower alkyl 3-phenoxy-1-azetidine carboxamides Granted JPS5764665A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
US06/029,800 US4226861A (en) 1978-04-18 1979-04-13 N-Lower-alkyl 3-phenoxy-1-azetidinecarboxamides
CH740880A CH645352A5 (en) 1978-04-18 1980-10-03 N-Lower alkyl-3-phenoxy-1-azetidinecarboxamides
FR8021340A FR2491467A1 (fr) 1978-04-18 1980-10-06 Nouveaux n-alkyl inferieur)-3-phenoxy-1-azetidinecarboxamides possedant notamment une activite sur le systeme nerveux central, et leur procede de preparation
BE0/202346A BE885549A (fr) 1978-04-18 1980-10-06 N-alkyl inferieur-3-phenoxy-1-azetidine-carboxamides
JP55139734A JPS5764665A (en) 1978-04-18 1980-10-06 N-lower alkyl 3-phenoxy-1-azetidine carboxamides
NL8005514A NL191314C (nl) 1978-04-18 1980-10-06 3-Monogesubstitueerd-1-azetidine-carboxamidederivaat, alsmede een anticonvulsief preparaat.
GB8032104A GB2084993B (en) 1978-04-18 1980-10-06 N-lower-alkyl 3-phenoxy-1-azetidine-carboxamides
DE3037770A DE3037770C2 (de) 1978-04-18 1980-10-06 N-Niedrigalkyl-3-phenoxy-1-azetidincarboxamide und diese Verbindungen enthaltende Zubereitungen
CA000361594A CA1161853A (en) 1978-04-18 1980-10-06 N-lower-alkyl 3-phenoxy-1-azetidine-carboxamides
AU32252/84A AU571258B2 (en) 1978-04-18 1984-08-21 N-lower alkyl-3-phenoxy-1-azetidinecarboxamides

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US89746278A 1978-04-18 1978-04-18
US06/029,800 US4226861A (en) 1978-04-18 1979-04-13 N-Lower-alkyl 3-phenoxy-1-azetidinecarboxamides
CH740880A CH645352A5 (en) 1978-04-18 1980-10-03 N-Lower alkyl-3-phenoxy-1-azetidinecarboxamides
FR8021340A FR2491467A1 (fr) 1978-04-18 1980-10-06 Nouveaux n-alkyl inferieur)-3-phenoxy-1-azetidinecarboxamides possedant notamment une activite sur le systeme nerveux central, et leur procede de preparation
JP55139734A JPS5764665A (en) 1978-04-18 1980-10-06 N-lower alkyl 3-phenoxy-1-azetidine carboxamides
NL8005514A NL191314C (nl) 1978-04-18 1980-10-06 3-Monogesubstitueerd-1-azetidine-carboxamidederivaat, alsmede een anticonvulsief preparaat.
GB8032104A GB2084993B (en) 1978-04-18 1980-10-06 N-lower-alkyl 3-phenoxy-1-azetidine-carboxamides
DE3037770A DE3037770C2 (de) 1978-04-18 1980-10-06 N-Niedrigalkyl-3-phenoxy-1-azetidincarboxamide und diese Verbindungen enthaltende Zubereitungen
CA000361594A CA1161853A (en) 1978-04-18 1980-10-06 N-lower-alkyl 3-phenoxy-1-azetidine-carboxamides
AU32252/84A AU571258B2 (en) 1978-04-18 1984-08-21 N-lower alkyl-3-phenoxy-1-azetidinecarboxamides

Publications (2)

Publication Number Publication Date
JPS5764665A true JPS5764665A (en) 1982-04-19
JPS643185B2 JPS643185B2 (ja) 1989-01-19

Family

ID=27578959

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55139734A Granted JPS5764665A (en) 1978-04-18 1980-10-06 N-lower alkyl 3-phenoxy-1-azetidine carboxamides

Country Status (9)

Country Link
US (1) US4226861A (ja)
JP (1) JPS5764665A (ja)
BE (1) BE885549A (ja)
CA (1) CA1161853A (ja)
CH (1) CH645352A5 (ja)
DE (1) DE3037770C2 (ja)
FR (1) FR2491467A1 (ja)
GB (1) GB2084993B (ja)
NL (1) NL191314C (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5980657A (ja) * 1982-08-19 1984-05-10 エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド ３−フエノキシ−１−アゼチジンカルボキサミド、その製造方法及びそれからなる鎮痙剤
JPS61205254A (ja) * 1985-02-28 1986-09-11 エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド 筋弛緩薬および抗不安薬としての３‐アリールオキシアゼチジンカルボキサミド含有組成物
JPS61210031A (ja) * 1985-02-28 1986-09-18 エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド 抗けいれん剤および抗てんかん剤としての３‐アリルオキシアゼチジンカルボキサミド

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4379151A (en) * 1978-03-14 1983-04-05 A. H. Robins Company, Inc. 3-Phenoxyazetidines for anorexigenic activity
US4571393A (en) * 1982-08-19 1986-02-18 A. H. Robins Company, Incorporated 3-Phenoxy-1-azetidinecarboxamides
US4505907A (en) * 1982-09-02 1985-03-19 A. H. Robins Company, Inc. N-Formyl and N-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides
US4594189A (en) * 1983-07-06 1986-06-10 A. H. Robins Company, Inc. Process for preparing 3-phenoxy-1-azetidines and carboxamide derivatives
US5151418A (en) * 1985-02-28 1992-09-29 A. H. Robins Company, Incorporated Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides
FI87559C (fi) * 1985-02-28 1993-01-25 Robins Co Inc A H Foerfarande foer framstaellning av aktiva 3-fenyloxiazetidinkarboxamider
US5183902A (en) * 1985-02-28 1993-02-02 A. H. Robins Company, Incorporated Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides
US4956359A (en) * 1985-02-28 1990-09-11 A. H. Robins Company, Inc. 3-aryloxy and 3-arylthioazetidinecarboxamides as anticonvulsants and antiepileptics
US5068231A (en) * 1985-02-28 1991-11-26 A. H. Robins Company Incorporated Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides
US5095014A (en) * 1990-12-07 1992-03-10 A. H. Robins Company, Incorporated 3-(2-chloro-4-(trifluoromethyl)phenoxy)-1-azetidine carboxamides having anticonvulsant activity
US5130309A (en) * 1991-04-12 1992-07-14 A. H. Robins Company, Incorporated Aryloxy and aryloxyalklazetidines as antiarrhythmic and anticonvulsant agents
US5183903A (en) * 1991-11-26 1993-02-02 A. H. Robins Company, Incorporated Urea fusion process for the synthesis of 3-phenoxy-1-azetidinecarboxamides
GB9801501D0 (en) 1998-01-23 1998-03-18 Cerebrus Ltd Chemical compounds - II
AU2178099A (en) 1998-01-23 1999-08-09 Vernalis Research Limited Azetidinecarboxamide derivatives for treating cns disorders
WO1999037612A1 (en) 1998-01-23 1999-07-29 Vernalis Research Limited Azetidinecarboxamide derivatives for treating cns disorders
GB9917386D0 (en) * 1999-07-23 1999-09-22 Cerebrus Ltd Chemical compounds-II

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1147585B (de) * 1958-12-23 1963-04-25 Lepetit Spa Verfahren zur Herstellung von 1-Carbamylazetidinen (1-Carbamyl-trimethyleniminen)
FR1332510A (fr) * 1959-12-07 1963-07-19 Lepetit Spa Procédé pour la préparation de nouvelles carbamylazétidines
DE2053333A1 (de) * 1970-10-30 1972-05-04 Farbenfabriken Bayer Ag, 5090 Lever Kusen Herbizide Mittel
US4031221A (en) * 1974-06-17 1977-06-21 American Hoechst Corporation Method of treating pain and hypertension
US4379151A (en) * 1978-03-14 1983-04-05 A. H. Robins Company, Inc. 3-Phenoxyazetidines for anorexigenic activity

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5980657A (ja) * 1982-08-19 1984-05-10 エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド ３−フエノキシ−１−アゼチジンカルボキサミド、その製造方法及びそれからなる鎮痙剤
JPS61205254A (ja) * 1985-02-28 1986-09-11 エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド 筋弛緩薬および抗不安薬としての３‐アリールオキシアゼチジンカルボキサミド含有組成物
JPS61210031A (ja) * 1985-02-28 1986-09-18 エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド 抗けいれん剤および抗てんかん剤としての３‐アリルオキシアゼチジンカルボキサミド

Also Published As

Publication number Publication date
GB2084993A (en) 1982-04-21
CA1161853A (en) 1984-02-07
JPS643185B2 (ja) 1989-01-19
US4226861A (en) 1980-10-07
NL191314C (nl) 1995-05-16
GB2084993B (en) 1984-07-11
BE885549A (fr) 1981-02-02
NL191314B (ja) 1994-12-16
FR2491467A1 (fr) 1982-04-09
NL8005514A (nl) 1982-05-03
DE3037770A1 (de) 1982-05-19
CH645352A5 (en) 1984-09-28
FR2491467B1 (ja) 1984-06-08
DE3037770C2 (de) 1994-11-10

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