NL189462C - Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan. - Google Patents
Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan.Info
- Publication number
- NL189462C NL189462C NLAANVRAGE8101509,A NL8101509A NL189462C NL 189462 C NL189462 C NL 189462C NL 8101509 A NL8101509 A NL 8101509A NL 189462 C NL189462 C NL 189462C
- Authority
- NL
- Netherlands
- Prior art keywords
- antiprolactinic
- pharmaceutical preparation
- ergoline derivatives
- antihypertensive properties
- antihypertensive
- Prior art date
Links
- AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical class O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 title 1
- 230000003276 anti-hypertensive effect Effects 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8011234 | 1980-04-03 | ||
| GB8011234 | 1980-04-03 | ||
| GB8040575 | 1980-12-18 | ||
| GB8040575 | 1980-12-18 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL8101509A NL8101509A (nl) | 1981-11-02 |
| NL189462B NL189462B (nl) | 1992-11-16 |
| NL189462C true NL189462C (nl) | 1993-04-16 |
Family
ID=26275073
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NLAANVRAGE8101509,A NL189462C (nl) | 1980-04-03 | 1981-03-26 | Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan. |
| NL930092C NL930092I1 (nl) | 1980-04-03 | 1993-06-24 | Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan |
| NL930091C NL930091I2 (nl) | 1980-04-03 | 1993-06-24 | Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL930092C NL930092I1 (nl) | 1980-04-03 | 1993-06-24 | Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan |
| NL930091C NL930091I2 (nl) | 1980-04-03 | 1993-06-24 | Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan. |
Country Status (20)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2173189B (en) * | 1985-02-21 | 1988-04-27 | Maruko Pharmaceutical Co | Ergoline derivatives and salts thereof and pharmaceutical compositions thereof |
| GB0409785D0 (en) | 2004-04-30 | 2004-06-09 | Resolution Chemicals Ltd | Preparation of cabergoline |
| GB0505965D0 (en) | 2005-03-23 | 2005-04-27 | Resolution Chemicals Ltd | Preparation of cabergoline |
| US7339060B2 (en) | 2005-03-23 | 2008-03-04 | Resolution Chemicals, Ltd. | Preparation of cabergoline |
| US7939665B2 (en) | 2007-05-04 | 2011-05-10 | Apotex Pharmachem Inc. | Efficient process for the preparation of cabergoline and its intermediates |
| EP2067780A1 (en) * | 2007-12-07 | 2009-06-10 | Axxonis Pharma AG | Ergoline derivatives as selective radical scavengers for neurons |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE396753B (sv) * | 1970-05-18 | 1977-10-03 | Richter Gedeon Vegyeszet | Analogiforfarande for framstellning av en forening tillhorande dihydrolysergsyraserien |
-
1981
- 1981-03-26 NL NLAANVRAGE8101509,A patent/NL189462C/xx not_active IP Right Cessation
- 1981-03-30 CH CH214481A patent/CH645896A5/de not_active IP Right Cessation
- 1981-03-30 IL IL62519A patent/IL62519A/xx not_active IP Right Cessation
- 1981-03-30 CA CA000374134A patent/CA1156648A/en not_active Expired
- 1981-03-30 NZ NZ196670A patent/NZ196670A/xx unknown
- 1981-03-30 AT AT0148481A patent/AT375076B/de not_active IP Right Cessation
- 1981-03-31 DE DE19813112861 patent/DE3112861A1/de active Granted
- 1981-03-31 AU AU68937/81A patent/AU540621B2/en not_active Expired
- 1981-03-31 FR FR8106422A patent/FR2479829B1/fr not_active Expired
- 1981-03-31 ES ES500911A patent/ES8202003A1/es not_active Expired
- 1981-03-31 YU YU851/81A patent/YU43011B/xx unknown
- 1981-04-01 PT PT72785A patent/PT72785B/pt unknown
- 1981-04-01 IT IT8120866A patent/IT1210473B/it active
- 1981-04-01 IT IT20865/81A patent/IT1205241B/it active Protection Beyond IP Right Term
- 1981-04-01 IE IE754/81A patent/IE51130B1/en not_active IP Right Cessation
- 1981-04-01 GR GR64542A patent/GR74806B/el unknown
- 1981-04-02 DK DK150781A patent/DK148686C/da not_active IP Right Cessation
- 1981-04-02 SE SE8102131A patent/SE442637B/sv not_active IP Right Cessation
- 1981-04-02 FI FI811025A patent/FI70412C/fi not_active IP Right Cessation
-
1987
- 1987-09-17 HK HK672/87A patent/HK67287A/xx not_active IP Right Cessation
-
1991
- 1991-12-30 CS CS914152A patent/CS415291A3/cs unknown
-
1993
- 1993-06-24 NL NL930092C patent/NL930092I1/nl unknown
- 1993-06-24 NL NL930091C patent/NL930091I2/nl unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BT | A notification was added to the application dossier and made available to the public | ||
| A85 | Still pending on 85-01-01 | ||
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| CNR | Transfer of rights (patent application after its laying open for public inspection) |
Free format text: ERBAMONT INDUSTRIALE S.R.L. |
|
| DNT | Communications of changes of names of applicants whose applications have been laid open to public inspection |
Free format text: ERBA S.R.L. FARMITALIA CARLO - |
|
| AC1 | Application for a supplementary protection certificate |
Free format text: 930092, 930624 |
|
| KC1 | Grant of a supplementary protection certificate |
Free format text: 930091, 20010325, EXPIRES:20020106 |
|
| SNR | Assignments of patents or rights arising from examined patent applications |
Owner name: PHARMACIA S.P.A. |
|
| BC1 | Further communications concerning applications for a supplementary protection certificate |
Free format text: 930092 |
|
| AC1 | Application for a supplementary protection certificate |
Free format text: 930091, 930624;930092, 930624 |
|
| TNT | Modifications of names of proprietors of patents or applicants of examined patent applications |
Owner name: PHARMACIA & UPJOHN S.P.A. |
|
| BC1 | Further communications concerning applications for a supplementary protection certificate |
Free format text: 930092 |
|
| V4 | Discontinued because of reaching the maximum lifetime of a patent |
Free format text: 20010326 |