NL189258C - Zout van 3-isobutoxy-2-pyrrolidino-n-fenyl-n-benzyl-propylamine met cardiovasculaire eigenschappen, alsmede geneesmiddel dat dit zout bevat. - Google Patents
Zout van 3-isobutoxy-2-pyrrolidino-n-fenyl-n-benzyl-propylamine met cardiovasculaire eigenschappen, alsmede geneesmiddel dat dit zout bevat.Info
- Publication number
- NL189258C NL189258C NLAANVRAGE7800753,A NL7800753A NL189258C NL 189258 C NL189258 C NL 189258C NL 7800753 A NL7800753 A NL 7800753A NL 189258 C NL189258 C NL 189258C
- Authority
- NL
- Netherlands
- Prior art keywords
- salt
- pyrrolidino
- isobutoxy
- propylamine
- benzyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7702058A FR2378024A1 (fr) | 1977-01-25 | 1977-01-25 | Nouvelle propylamine substituee, obtention et application |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL7800753A NL7800753A (nl) | 1978-07-27 |
| NL189258B NL189258B (nl) | 1992-09-16 |
| NL189258C true NL189258C (nl) | 1993-02-16 |
Family
ID=9185890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NLAANVRAGE7800753,A NL189258C (nl) | 1977-01-25 | 1978-01-20 | Zout van 3-isobutoxy-2-pyrrolidino-n-fenyl-n-benzyl-propylamine met cardiovasculaire eigenschappen, alsmede geneesmiddel dat dit zout bevat. |
Country Status (12)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR8208033A (pt) * | 1981-12-28 | 1983-11-22 | Carter Wallace | Processo quimico |
| DK156396C (da) * | 1983-09-27 | 1990-01-08 | Cerm Cent Europ Rech Mauvernay | 2-(n-pyrrolidino)-3-isobutoxy-n-substituerede phenyl-n-benzyl-propylamin-forbindelser og farmaceutiske midler indeholdende disse |
| GB8330197D0 (en) * | 1983-11-11 | 1983-12-21 | Akzo Nv | Ether of n-propanolamine derivative |
| EP0146159B1 (en) * | 1983-11-11 | 1988-01-13 | Akzo N.V. | Ether of n-propanolamine derivative |
| FR2558160B1 (fr) * | 1984-01-18 | 1986-05-30 | Cerm Cent Europ Rech Mauvernay | 3-alkoxy 2-(n-pyrrolidino)-n-pyrimidinyl ou -pyrazinyl propylamines, leur preparation et leur application en therapeutique |
| FR2558161B1 (fr) * | 1984-01-18 | 1987-01-23 | Cerm Cent Europ Rech Mauvernay | 3-alkoxy 2-(n-pyrrolidino) n-furylmethyl ou n-thienylmethyl n-pyridyl propylamines, leur preparation et leur application en therapeutique |
| FR2558159B1 (fr) * | 1984-01-18 | 1986-06-13 | Cerm Cent Europ Rech Mauvernay | 3-alkoxy 2-(n-pyrrolidino)-n-pyridyl-n-arylmethyl-propylamines, leur preparation et leur application en therapeutique |
| DE3726633A1 (de) * | 1987-08-11 | 1989-02-23 | Boehringer Mannheim Gmbh | Neue 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
| DE3726632A1 (de) * | 1987-08-11 | 1989-05-18 | Boehringer Mannheim Gmbh | 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
| JP2678758B2 (ja) * | 1988-02-16 | 1997-11-17 | 興和株式会社 | 新規なプロパン誘導体 |
| WO2016098128A1 (en) * | 2014-12-16 | 2016-06-23 | Council Of Scientific & Industrial Research | Process for the preparation of bepridil |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE795735A (fr) * | 1972-03-06 | 1973-06-18 | Cerm Cent Europ Rech Mauvernay | Nouvelles ethylenediamines substituees a activite cardiovasculaire |
-
1977
- 1977-01-25 FR FR7702058A patent/FR2378024A1/fr active Granted
- 1977-10-03 JP JP11797777A patent/JPS5392764A/ja active Granted
-
1978
- 1978-01-11 CH CH27378A patent/CH628889A5/fr not_active IP Right Cessation
- 1978-01-13 GB GB1506/78A patent/GB1595031A/en not_active Expired
- 1978-01-16 IL IL53816A patent/IL53816A0/xx not_active IP Right Cessation
- 1978-01-20 PT PT67556A patent/PT67556B/pt unknown
- 1978-01-20 NL NLAANVRAGE7800753,A patent/NL189258C/xx not_active IP Right Cessation
- 1978-01-21 ES ES466237A patent/ES466237A1/es not_active Expired
- 1978-01-23 AU AU32660/78A patent/AU516479B2/en not_active Expired
- 1978-01-23 BE BE184554A patent/BE863214A/xx not_active IP Right Cessation
- 1978-01-24 ZA ZA00780426A patent/ZA78426B/xx unknown
- 1978-01-24 DE DE2802864A patent/DE2802864C2/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA78426B (en) | 1979-01-31 |
| AU3266078A (en) | 1979-08-02 |
| JPS5392764A (en) | 1978-08-15 |
| PT67556A (fr) | 1978-02-01 |
| AU516479B2 (en) | 1981-06-04 |
| ES466237A1 (es) | 1978-10-16 |
| CH628889A5 (en) | 1982-03-31 |
| GB1595031A (en) | 1981-08-05 |
| NL189258B (nl) | 1992-09-16 |
| BE863214A (fr) | 1978-07-24 |
| PT67556B (fr) | 1979-06-18 |
| DE2802864C2 (de) | 1982-12-09 |
| FR2378024A1 (fr) | 1978-08-18 |
| IL53816A0 (en) | 1978-04-30 |
| NL7800753A (nl) | 1978-07-27 |
| FR2378024B1 (US20110232667A1-20110929-C00004.png) | 1979-05-11 |
| JPS5429493B2 (US20110232667A1-20110929-C00004.png) | 1979-09-25 |
| DE2802864A1 (de) | 1978-07-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| BC | A request for examination has been filed | ||
| A85 | Still pending on 85-01-01 | ||
| BV | The patent application has lapsed | ||
| DNT | Communications of changes of names of applicants whose applications have been laid open to public inspection |
Free format text: "RL-CERM" S.A. "RIOM-LABORATOIRES-C.E.R.M." AFGEKORT - |
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| V4 | Discontinued because of reaching the maximum lifetime of a patent |
Free format text: 980120 |