BE863214A - Nouvelle propylamine substituee, obtention et application - Google Patents

Nouvelle propylamine substituee, obtention et application

Info

Publication number
BE863214A
BE863214A BE184554A BE184554A BE863214A BE 863214 A BE863214 A BE 863214A BE 184554 A BE184554 A BE 184554A BE 184554 A BE184554 A BE 184554A BE 863214 A BE863214 A BE 863214A
Authority
BE
Belgium
Prior art keywords
obtaining
applying
new substituted
substituted propylamine
propylamine
Prior art date
Application number
BE184554A
Other languages
English (en)
Inventor
R Y Mauvernay
N Busch
J Simond
A Monteil
J Moleyre
Original Assignee
Ct Europ De Rech S Mauvernay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Europ De Rech S Mauvernay filed Critical Ct Europ De Rech S Mauvernay
Publication of BE863214A publication Critical patent/BE863214A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE184554A 1977-01-25 1978-01-23 Nouvelle propylamine substituee, obtention et application BE863214A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7702058A FR2378024A1 (fr) 1977-01-25 1977-01-25 Nouvelle propylamine substituee, obtention et application

Publications (1)

Publication Number Publication Date
BE863214A true BE863214A (fr) 1978-07-24

Family

ID=9185890

Family Applications (1)

Application Number Title Priority Date Filing Date
BE184554A BE863214A (fr) 1977-01-25 1978-01-23 Nouvelle propylamine substituee, obtention et application

Country Status (12)

Country Link
JP (1) JPS5392764A (fr)
AU (1) AU516479B2 (fr)
BE (1) BE863214A (fr)
CH (1) CH628889A5 (fr)
DE (1) DE2802864C2 (fr)
ES (1) ES466237A1 (fr)
FR (1) FR2378024A1 (fr)
GB (1) GB1595031A (fr)
IL (1) IL53816A0 (fr)
NL (1) NL189258C (fr)
PT (1) PT67556B (fr)
ZA (1) ZA78426B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983002274A1 (fr) * 1981-12-28 1983-07-07 Carter Wallace Synthese de l'hydrochlorure de 1-(3-isobutoxy-2-(phenylbenzyl)-amino)-propyl-pyrrolydino
DK156396C (da) * 1983-09-27 1990-01-08 Cerm Cent Europ Rech Mauvernay 2-(n-pyrrolidino)-3-isobutoxy-n-substituerede phenyl-n-benzyl-propylamin-forbindelser og farmaceutiske midler indeholdende disse
GB8330197D0 (en) * 1983-11-11 1983-12-21 Akzo Nv Ether of n-propanolamine derivative
DE3468684D1 (de) * 1983-11-11 1988-02-18 Akzo Nv Ether of n-propanolamine derivative
FR2558161B1 (fr) * 1984-01-18 1987-01-23 Cerm Cent Europ Rech Mauvernay 3-alkoxy 2-(n-pyrrolidino) n-furylmethyl ou n-thienylmethyl n-pyridyl propylamines, leur preparation et leur application en therapeutique
FR2558160B1 (fr) * 1984-01-18 1986-05-30 Cerm Cent Europ Rech Mauvernay 3-alkoxy 2-(n-pyrrolidino)-n-pyrimidinyl ou -pyrazinyl propylamines, leur preparation et leur application en therapeutique
FR2558159B1 (fr) * 1984-01-18 1986-06-13 Cerm Cent Europ Rech Mauvernay 3-alkoxy 2-(n-pyrrolidino)-n-pyridyl-n-arylmethyl-propylamines, leur preparation et leur application en therapeutique
DE3726632A1 (de) * 1987-08-11 1989-05-18 Boehringer Mannheim Gmbh 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE3726633A1 (de) * 1987-08-11 1989-02-23 Boehringer Mannheim Gmbh Neue 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
JP2678758B2 (ja) * 1988-02-16 1997-11-17 興和株式会社 新規なプロパン誘導体
WO2016098128A1 (fr) * 2014-12-16 2016-06-23 Council Of Scientific & Industrial Research Procédé de préparation de bépridil

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795735A (fr) * 1972-03-06 1973-06-18 Cerm Cent Europ Rech Mauvernay Nouvelles ethylenediamines substituees a activite cardiovasculaire

Also Published As

Publication number Publication date
PT67556A (fr) 1978-02-01
NL7800753A (nl) 1978-07-27
FR2378024A1 (fr) 1978-08-18
NL189258C (nl) 1993-02-16
IL53816A0 (en) 1978-04-30
ZA78426B (en) 1979-01-31
AU3266078A (en) 1979-08-02
DE2802864C2 (de) 1982-12-09
GB1595031A (en) 1981-08-05
FR2378024B1 (fr) 1979-05-11
JPS5429493B2 (fr) 1979-09-25
NL189258B (nl) 1992-09-16
AU516479B2 (en) 1981-06-04
JPS5392764A (en) 1978-08-15
ES466237A1 (es) 1978-10-16
PT67556B (fr) 1979-06-18
DE2802864A1 (de) 1978-07-27
CH628889A5 (en) 1982-03-31

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: CENTRE EUROPEEN DE RECHERCHES MAUVERNAY

Effective date: 19980123