NL189258C - SALT OF 3-ISOBUTOXY-2-PYRROLIDINO-N-PHENYL-N-BENZYL-PROPYLAMINE WITH CARDIOVASCULAR PROPERTIES, AND THE MEDICINAL PRODUCT CONTAINING THIS SALT. - Google Patents

SALT OF 3-ISOBUTOXY-2-PYRROLIDINO-N-PHENYL-N-BENZYL-PROPYLAMINE WITH CARDIOVASCULAR PROPERTIES, AND THE MEDICINAL PRODUCT CONTAINING THIS SALT.

Info

Publication number
NL189258C
NL189258C NLAANVRAGE7800753,A NL7800753A NL189258C NL 189258 C NL189258 C NL 189258C NL 7800753 A NL7800753 A NL 7800753A NL 189258 C NL189258 C NL 189258C
Authority
NL
Netherlands
Prior art keywords
salt
pyrrolidino
isobutoxy
propylamine
benzyl
Prior art date
Application number
NLAANVRAGE7800753,A
Other languages
Dutch (nl)
Other versions
NL189258B (en
NL7800753A (en
Original Assignee
Cerm Cent Europ Rech Mauvernay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerm Cent Europ Rech Mauvernay filed Critical Cerm Cent Europ Rech Mauvernay
Publication of NL7800753A publication Critical patent/NL7800753A/en
Publication of NL189258B publication Critical patent/NL189258B/en
Application granted granted Critical
Publication of NL189258C publication Critical patent/NL189258C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NLAANVRAGE7800753,A 1977-01-25 1978-01-20 SALT OF 3-ISOBUTOXY-2-PYRROLIDINO-N-PHENYL-N-BENZYL-PROPYLAMINE WITH CARDIOVASCULAR PROPERTIES, AND THE MEDICINAL PRODUCT CONTAINING THIS SALT. NL189258C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7702058A FR2378024A1 (en) 1977-01-25 1977-01-25 NEW SUBSTITUTED PROPYLAMINE, OBTAINING AND APPLYING

Publications (3)

Publication Number Publication Date
NL7800753A NL7800753A (en) 1978-07-27
NL189258B NL189258B (en) 1992-09-16
NL189258C true NL189258C (en) 1993-02-16

Family

ID=9185890

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7800753,A NL189258C (en) 1977-01-25 1978-01-20 SALT OF 3-ISOBUTOXY-2-PYRROLIDINO-N-PHENYL-N-BENZYL-PROPYLAMINE WITH CARDIOVASCULAR PROPERTIES, AND THE MEDICINAL PRODUCT CONTAINING THIS SALT.

Country Status (12)

Country Link
JP (1) JPS5392764A (en)
AU (1) AU516479B2 (en)
BE (1) BE863214A (en)
CH (1) CH628889A5 (en)
DE (1) DE2802864C2 (en)
ES (1) ES466237A1 (en)
FR (1) FR2378024A1 (en)
GB (1) GB1595031A (en)
IL (1) IL53816A0 (en)
NL (1) NL189258C (en)
PT (1) PT67556B (en)
ZA (1) ZA78426B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3278160D1 (en) * 1981-12-28 1988-04-07 Carter Wallace Process for the preparation of b-û(2-methylpropoxy)-methyl¨-n-phenyl-n-(phenylmethyl)-1-pyrrolidineethanamine
DK156396C (en) * 1983-09-27 1990-01-08 Cerm Cent Europ Rech Mauvernay 2- (N-PYRROLIDINO) -3-ISOBUTOXY-N-SUBSTITUTED PHENYL-N-BENZYL-PROPYLAMINE COMPOUNDS AND PHARMACEUTICAL AGENTS CONTAINING THESE
EP0146159B1 (en) * 1983-11-11 1988-01-13 Akzo N.V. Ether of n-propanolamine derivative
GB8330197D0 (en) * 1983-11-11 1983-12-21 Akzo Nv Ether of n-propanolamine derivative
FR2558161B1 (en) * 1984-01-18 1987-01-23 Cerm Cent Europ Rech Mauvernay 3-ALKOXY 2- (N-PYRROLIDINO) N-FURYLMETHYL OR N-THIENYLMETHYL N-PYRIDYL PROPYLAMINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2558160B1 (en) * 1984-01-18 1986-05-30 Cerm Cent Europ Rech Mauvernay 3-ALKOXY 2- (N-PYRROLIDINO) -N-PYRIMIDINYL OR -PYRAZINYL PROPYLAMINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2558159B1 (en) * 1984-01-18 1986-06-13 Cerm Cent Europ Rech Mauvernay 3-ALKOXY 2- (N-PYRROLIDINO) -N-PYRIDYL-N-ARYLMETHYL-PROPYLAMINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
DE3726632A1 (en) * 1987-08-11 1989-05-18 Boehringer Mannheim Gmbh 1,2-DIAMINO COMPOUNDS, METHOD FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3726633A1 (en) * 1987-08-11 1989-02-23 Boehringer Mannheim Gmbh NEW 1,2-DIAMINO COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
JP2678758B2 (en) * 1988-02-16 1997-11-17 興和株式会社 Novel propane derivative
WO2016098128A1 (en) * 2014-12-16 2016-06-23 Council Of Scientific & Industrial Research Process for the preparation of bepridil

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795735A (en) * 1972-03-06 1973-06-18 Cerm Cent Europ Rech Mauvernay NEW ETHYLENEDIAMINES SUBSTITUTES WITH CARDIOVASCULAR ACTIVITY

Also Published As

Publication number Publication date
BE863214A (en) 1978-07-24
FR2378024A1 (en) 1978-08-18
GB1595031A (en) 1981-08-05
JPS5429493B2 (en) 1979-09-25
DE2802864A1 (en) 1978-07-27
JPS5392764A (en) 1978-08-15
CH628889A5 (en) 1982-03-31
IL53816A0 (en) 1978-04-30
DE2802864C2 (en) 1982-12-09
NL189258B (en) 1992-09-16
ZA78426B (en) 1979-01-31
PT67556A (en) 1978-02-01
NL7800753A (en) 1978-07-27
AU516479B2 (en) 1981-06-04
PT67556B (en) 1979-06-18
AU3266078A (en) 1979-08-02
ES466237A1 (en) 1978-10-16
FR2378024B1 (en) 1979-05-11

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