FR2378024A1 - NEW SUBSTITUTED PROPYLAMINE, OBTAINING AND APPLYING - Google Patents
NEW SUBSTITUTED PROPYLAMINE, OBTAINING AND APPLYINGInfo
- Publication number
- FR2378024A1 FR2378024A1 FR7702058A FR7702058A FR2378024A1 FR 2378024 A1 FR2378024 A1 FR 2378024A1 FR 7702058 A FR7702058 A FR 7702058A FR 7702058 A FR7702058 A FR 7702058A FR 2378024 A1 FR2378024 A1 FR 2378024A1
- Authority
- FR
- France
- Prior art keywords
- obtaining
- applying
- new substituted
- propylamine
- substituted propylamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Abstract
3-isobutoxy 2-pyrrolidino N-phényl N-benzyl propylamine. Ce composé présente une masse moléculaire M de 366 et un point d'ébullition E0 3 de 192 degrés C. Application au traitement des affections cardiovasculaires, notamment au traitement de l'angor.3-isobutoxy 2-pyrrolidino N-phenyl N-benzyl propylamine. This compound has a molecular mass M of 366 and a boiling point E0 3 of 192 degrees C. Application to the treatment of cardiovascular disorders, in particular to the treatment of angina.
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7702058A FR2378024A1 (en) | 1977-01-25 | 1977-01-25 | NEW SUBSTITUTED PROPYLAMINE, OBTAINING AND APPLYING |
JP11797777A JPS5392764A (en) | 1977-01-25 | 1977-10-03 | Novel substituted propylamine and method for its production |
CH27378A CH628889A5 (en) | 1977-01-25 | 1978-01-11 | Substituted propylamine, process for its preparation and pharmaceutical composition containing this compound |
GB1506/78A GB1595031A (en) | 1977-01-25 | 1978-01-13 | 3-isobutoxy-2-pyrrolidino-n-phenyl-n-benzyl propylamine and its salts |
IL53816A IL53816A0 (en) | 1977-01-25 | 1978-01-16 | A new substituted propylamine, its preparation and pharmaceutical compositions containing it |
GR55207A GR64868B7 (en) | 1973-02-28 | 1978-01-19 | Method for the preparation of novel substituted propilamine |
NLAANVRAGE7800753,A NL189258C (en) | 1977-01-25 | 1978-01-20 | SALT OF 3-ISOBUTOXY-2-PYRROLIDINO-N-PHENYL-N-BENZYL-PROPYLAMINE WITH CARDIOVASCULAR PROPERTIES, AND THE MEDICINAL PRODUCT CONTAINING THIS SALT. |
PT67556A PT67556B (en) | 1977-01-25 | 1978-01-20 | PROCESS FOR OBTAINING A NEW SUBSTITUTED PROPYLAMINE |
ES466237A ES466237A1 (en) | 1977-01-25 | 1978-01-21 | 3-isobutoxy-2-pyrrolidino-n-phenyl-n-benzyl propylamine and its salts |
AU32660/78A AU516479B2 (en) | 1977-01-25 | 1978-01-23 | Process for preparing 3-isobutoxy 2-pyrrolidino n-phenyl n-benzyl propylamine |
BE184554A BE863214A (en) | 1977-01-25 | 1978-01-23 | NEW SUBSTITUTED PROPYLAMINE, OBTAINING AND APPLYING |
ZA00780426A ZA78426B (en) | 1977-01-25 | 1978-01-24 | Substituted propylamine and a process for obtaining same |
DE2802864A DE2802864C2 (en) | 1977-01-25 | 1978-01-24 | Process for the preparation of 3-isobutoxy-2-pyrrolidino-N-phenyl-N-benzylpropylamine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7702058A FR2378024A1 (en) | 1977-01-25 | 1977-01-25 | NEW SUBSTITUTED PROPYLAMINE, OBTAINING AND APPLYING |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2378024A1 true FR2378024A1 (en) | 1978-08-18 |
FR2378024B1 FR2378024B1 (en) | 1979-05-11 |
Family
ID=9185890
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7702058A Granted FR2378024A1 (en) | 1973-02-28 | 1977-01-25 | NEW SUBSTITUTED PROPYLAMINE, OBTAINING AND APPLYING |
Country Status (12)
Country | Link |
---|---|
JP (1) | JPS5392764A (en) |
AU (1) | AU516479B2 (en) |
BE (1) | BE863214A (en) |
CH (1) | CH628889A5 (en) |
DE (1) | DE2802864C2 (en) |
ES (1) | ES466237A1 (en) |
FR (1) | FR2378024A1 (en) |
GB (1) | GB1595031A (en) |
IL (1) | IL53816A0 (en) |
NL (1) | NL189258C (en) |
PT (1) | PT67556B (en) |
ZA (1) | ZA78426B (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0138684A2 (en) * | 1983-09-27 | 1985-04-24 | Riom Laboratoires- C.E.R.M. "R.L.-Cerm" - (S.A.) | 2-(N-pyrrolidino)-3-isobutoxy-N-phenyl-substituted N-benzylpropyl amines, their preparation and their pharmaceutical use |
FR2558159A1 (en) * | 1984-01-18 | 1985-07-19 | Cerm Cent Europ Rech Mauvernay | 3-Alkoxy-2-(N-pyrrolidino)-N-pyridyl-N-arylmethylpropylamines, their preparation and their therapeutic use |
FR2558160A1 (en) * | 1984-01-18 | 1985-07-19 | Cerm Cent Europ Rech Mauvernay | 3-ALKOXY 2- (N-PYRROLIDINO) -N-PYRIMIDINYL OR -PYRAZINYL PROPYLAMINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
FR2558161A1 (en) * | 1984-01-18 | 1985-07-19 | Cerm Cent Europ Rech Mauvernay | 3-ALKOXY 2- (N-PYRROLIDINO) N-FURYLMETHYL OR N-THIENYLMETHYL N-PYRIDYL PROPYLAMINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
EP0303181A2 (en) * | 1987-08-11 | 1989-02-15 | Roche Diagnostics GmbH | 1,2-Diamine compounds, process for their preparation as well as medicaments containing these compounds |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE32715T1 (en) * | 1981-12-28 | 1988-03-15 | Carter Wallace | PROCESS FOR THE PREPARATION OF B-((2METHYLPROPOXY)-METHYL>-N-PHENYL-N-(PHENYLMETHYL - 1-PYRROLIDINETHANAMINE. |
GB8330197D0 (en) * | 1983-11-11 | 1983-12-21 | Akzo Nv | Ether of n-propanolamine derivative |
DE3468684D1 (en) * | 1983-11-11 | 1988-02-18 | Akzo Nv | ETHER OF N-PROPANOLAMINE DERIVATIVE |
DE3726633A1 (en) * | 1987-08-11 | 1989-02-23 | Boehringer Mannheim Gmbh | NEW 1,2-DIAMINO COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
JP2678758B2 (en) * | 1988-02-16 | 1997-11-17 | 興和株式会社 | Novel propane derivative |
WO2016098128A1 (en) * | 2014-12-16 | 2016-06-23 | Council Of Scientific & Industrial Research | Process for the preparation of bepridil |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2174655A1 (en) * | 1972-03-06 | 1973-10-19 | Mauvernay Ctre Rech |
-
1977
- 1977-01-25 FR FR7702058A patent/FR2378024A1/en active Granted
- 1977-10-03 JP JP11797777A patent/JPS5392764A/en active Granted
-
1978
- 1978-01-11 CH CH27378A patent/CH628889A5/en not_active IP Right Cessation
- 1978-01-13 GB GB1506/78A patent/GB1595031A/en not_active Expired
- 1978-01-16 IL IL53816A patent/IL53816A0/en not_active IP Right Cessation
- 1978-01-20 PT PT67556A patent/PT67556B/en unknown
- 1978-01-20 NL NLAANVRAGE7800753,A patent/NL189258C/en not_active IP Right Cessation
- 1978-01-21 ES ES466237A patent/ES466237A1/en not_active Expired
- 1978-01-23 AU AU32660/78A patent/AU516479B2/en not_active Expired
- 1978-01-23 BE BE184554A patent/BE863214A/en not_active IP Right Cessation
- 1978-01-24 ZA ZA00780426A patent/ZA78426B/en unknown
- 1978-01-24 DE DE2802864A patent/DE2802864C2/en not_active Expired
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2174655A1 (en) * | 1972-03-06 | 1973-10-19 | Mauvernay Ctre Rech |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0138684A2 (en) * | 1983-09-27 | 1985-04-24 | Riom Laboratoires- C.E.R.M. "R.L.-Cerm" - (S.A.) | 2-(N-pyrrolidino)-3-isobutoxy-N-phenyl-substituted N-benzylpropyl amines, their preparation and their pharmaceutical use |
EP0138684A3 (en) * | 1983-09-27 | 1985-06-19 | Riom Laboratoires- C.E.R.M. "R.L.-Cerm" - (S.A.) | 2-(n-pyrrolidino)-3-isobutoxy-n-phenyl-substituted n-benzylpropyl amines, their preparation and their pharmaceutical use |
FR2558159A1 (en) * | 1984-01-18 | 1985-07-19 | Cerm Cent Europ Rech Mauvernay | 3-Alkoxy-2-(N-pyrrolidino)-N-pyridyl-N-arylmethylpropylamines, their preparation and their therapeutic use |
FR2558160A1 (en) * | 1984-01-18 | 1985-07-19 | Cerm Cent Europ Rech Mauvernay | 3-ALKOXY 2- (N-PYRROLIDINO) -N-PYRIMIDINYL OR -PYRAZINYL PROPYLAMINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
FR2558161A1 (en) * | 1984-01-18 | 1985-07-19 | Cerm Cent Europ Rech Mauvernay | 3-ALKOXY 2- (N-PYRROLIDINO) N-FURYLMETHYL OR N-THIENYLMETHYL N-PYRIDYL PROPYLAMINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
EP0149583A2 (en) * | 1984-01-18 | 1985-07-24 | Riom Laboratoires- C.E.R.M. "R.L.-Cerm" - (S.A.) | 3-Alcoxy-2-(N-pyrrolidino)-N-pyridyl-N-furyl(or thienyl)-methyl propyl amines, their preparation and pharmaceutical compositions containing them |
EP0149583A3 (en) * | 1984-01-18 | 1985-08-07 | Riom Laboratoires- C.E.R.M. "R.L.-Cerm" - (S.A.) | 3-alcoxy-2-(n-pyrrolidino)-n-pyridyl-n-furyl(or thienyl)-methyl propyl amines, their preparation and pharmaceutical compositions containing them |
EP0151062A2 (en) * | 1984-01-18 | 1985-08-07 | Riom Laboratoires- C.E.R.M. "R.L.-Cerm" - (S.A.) | 3-Alkoxy-2-(N-pyrrolidino)-N-pyrimidinyl or N-pyrazinylpropylamines, their preparation and pharmaceutical compositions containing them |
EP0151062A3 (en) * | 1984-01-18 | 1985-08-21 | Riom Laboratoires- C.E.R.M. "R.L.-Cerm" - (S.A.) | 3-alkoxy-2-(n-pyrrolidino)-n-pyrimidinyl or n-pyrazinylpropylamines, their preparation and pharmaceutical compositions containing them |
EP0303181A2 (en) * | 1987-08-11 | 1989-02-15 | Roche Diagnostics GmbH | 1,2-Diamine compounds, process for their preparation as well as medicaments containing these compounds |
EP0303181A3 (en) * | 1987-08-11 | 1991-09-04 | Roche Diagnostics GmbH | 1,2-diamine compounds, process for their preparation as well as medicaments containing these compounds |
Also Published As
Publication number | Publication date |
---|---|
AU3266078A (en) | 1979-08-02 |
DE2802864C2 (en) | 1982-12-09 |
FR2378024B1 (en) | 1979-05-11 |
ES466237A1 (en) | 1978-10-16 |
BE863214A (en) | 1978-07-24 |
NL7800753A (en) | 1978-07-27 |
AU516479B2 (en) | 1981-06-04 |
NL189258B (en) | 1992-09-16 |
DE2802864A1 (en) | 1978-07-27 |
IL53816A0 (en) | 1978-04-30 |
ZA78426B (en) | 1979-01-31 |
CH628889A5 (en) | 1982-03-31 |
PT67556B (en) | 1979-06-18 |
GB1595031A (en) | 1981-08-05 |
PT67556A (en) | 1978-02-01 |
JPS5392764A (en) | 1978-08-15 |
JPS5429493B2 (en) | 1979-09-25 |
NL189258C (en) | 1993-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CD | Change of name or company name |