NL179906C - Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten. - Google Patents

Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten.

Info

Publication number
NL179906C
NL179906C NLAANVRAGE7401807,A NL7401807A NL179906C NL 179906 C NL179906 C NL 179906C NL 7401807 A NL7401807 A NL 7401807A NL 179906 C NL179906 C NL 179906C
Authority
NL
Netherlands
Prior art keywords
hexahydrodibenzo
pyrazino
preparing
azepine derivatives
azepine
Prior art date
Application number
NLAANVRAGE7401807,A
Other languages
English (en)
Dutch (nl)
Other versions
NL7401807A (nl
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Priority to NLAANVRAGE7401807,A priority Critical patent/NL179906C/xx
Priority to GB39732/76A priority patent/GB1498633A/en
Priority to GB3670/75A priority patent/GB1498632A/en
Priority to DK032375A priority patent/DK150144C/da
Priority to FI750327A priority patent/FI57106C/fi
Priority to CH143875A priority patent/CH613705A5/xx
Priority to US05/547,680 priority patent/US4025513A/en
Priority to FR7503954A priority patent/FR2260579B1/fr
Priority to ES434533A priority patent/ES434533A1/es
Priority to SE7501365A priority patent/SE418745B/xx
Priority to DE19752505239 priority patent/DE2505239A1/de
Priority to JP1615675A priority patent/JPS5315520B2/ja
Priority to HUAO404A priority patent/HU169018B/hu
Priority to CA219,742A priority patent/CA1084490A/en
Publication of NL7401807A publication Critical patent/NL7401807A/xx
Priority to US05/754,216 priority patent/US4217452A/en
Priority to US06/064,812 priority patent/US4254031A/en
Application granted granted Critical
Publication of NL179906C publication Critical patent/NL179906C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/04—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NLAANVRAGE7401807,A 1974-02-09 1974-02-09 Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten. NL179906C (nl)

Priority Applications (16)

Application Number Priority Date Filing Date Title
NLAANVRAGE7401807,A NL179906C (nl) 1974-02-09 1974-02-09 Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten.
GB39732/76A GB1498633A (en) 1974-02-09 1975-01-28 2-phenyl-piperazines and 4-phenyl-hexahydro pyrimidines
GB3670/75A GB1498632A (en) 1974-02-09 1975-01-28 Preparation of 1,2,3,4,10,14b-hexahydro-dibenzo(c,f)-pyrazino(1,2-a)azepines and 1,2,3,4,10,14b-dibenzo-(c,f)-pyrimidino(3,4-a)-azepines
DK032375A DK150144C (da) 1974-02-09 1975-01-30 Fremgangsmaade til fremstilling af tetracykliske, kondenserede pyrazinderivater
CH143875A CH613705A5 (da) 1974-02-09 1975-02-06
US05/547,680 US4025513A (en) 1974-02-09 1975-02-06 Synthesis for the preparation of tetracyclic compounds
FI750327A FI57106C (fi) 1974-02-09 1975-02-06 Foerfarande foer framstaellning av dibenso(c,f)-pyrazino(1,2-a)-azepinderivat
ES434533A ES434533A1 (es) 1974-02-09 1975-02-07 Un procedimiento para la preparacion de compuestos tetraci-clicos.
FR7503954A FR2260579B1 (da) 1974-02-09 1975-02-07
SE7501365A SE418745B (sv) 1974-02-09 1975-02-07 Forfarande for framstellning av tetracykliska azepinforeningar
DE19752505239 DE2505239A1 (de) 1974-02-09 1975-02-07 Verfahren zur herstellung tetracyclischer verbindungen
JP1615675A JPS5315520B2 (da) 1974-02-09 1975-02-07
HUAO404A HU169018B (da) 1974-02-09 1975-02-07
CA219,742A CA1084490A (en) 1974-02-09 1975-02-10 Synthesis for the preparation of tetracyclic compounds
US05/754,216 US4217452A (en) 1974-02-09 1976-12-27 Synthesis for the preparation of tetracyclic compounds
US06/064,812 US4254031A (en) 1974-02-09 1979-08-08 Synthesis for the preparation of tetracyclic compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NLAANVRAGE7401807,A NL179906C (nl) 1974-02-09 1974-02-09 Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten.

Publications (2)

Publication Number Publication Date
NL7401807A NL7401807A (nl) 1975-08-12
NL179906C true NL179906C (nl) 1986-12-01

Family

ID=19820725

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7401807,A NL179906C (nl) 1974-02-09 1974-02-09 Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten.

Country Status (13)

Country Link
US (2) US4025513A (da)
JP (1) JPS5315520B2 (da)
CA (1) CA1084490A (da)
CH (1) CH613705A5 (da)
DE (1) DE2505239A1 (da)
DK (1) DK150144C (da)
ES (1) ES434533A1 (da)
FI (1) FI57106C (da)
FR (1) FR2260579B1 (da)
GB (2) GB1498632A (da)
HU (1) HU169018B (da)
NL (1) NL179906C (da)
SE (1) SE418745B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5655174U (da) * 1979-10-06 1981-05-14
EP0088575B1 (en) * 1982-03-05 1986-12-30 Beecham Group Plc Pentacyclic compounds
US4515792A (en) * 1982-09-30 1985-05-07 Ciba-Geigy Corporation Tetracyclic heterocycles and antidepressant compositions thereof
GB2138016B (en) * 1983-04-05 1986-10-29 Bostik Ltd Adhesive bonding
RU2048469C1 (ru) * 1989-10-05 1995-11-20 Санкио Компани Лимитед Способ получения азетидинового производного или его фармацевтически приемлемой соли
EP0539164A1 (en) * 1991-10-23 1993-04-28 Sankyo Company Limited Nitrogen-containing tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use
DE4305659A1 (de) * 1993-02-24 1994-08-25 Heumann Pharma Gmbh & Co Verfahren zur Herstellung von 1,2,3,4,10,14b-Hexahydro-2-methyl-dibenzo[c,f]pyrazino[1,2-a]azepin und seiner Salze
EP1017695A4 (en) * 1997-09-26 2002-01-16 Univ Monash RESOLUTION OF OPTICALLY ACTIVE COMPOUNDS
AU777105B2 (en) * 1999-04-19 2004-09-30 Teva Pharmaceutical Industries Ltd. Novel synthesis of piperazine ring
AU6476300A (en) 1999-09-30 2001-05-10 Sumika Fine Chemicals Co., Ltd. Process for the preparation of a piperazine derivative
EP2291181B9 (en) 2008-04-18 2013-09-11 University College Dublin National University Of Ireland, Dublin Captodiamine for the treatment of depression symptoms
CN102649779A (zh) * 2012-04-20 2012-08-29 山东鲁药制药有限公司 一种药物中间体1-甲基-3-苯基哌嗪的合成方法
CN102911793B (zh) * 2012-10-04 2013-10-23 盐城师范学院 一种功能化碱性离子液体及其在生物柴油制备中的应用
CN102876466B (zh) * 2012-10-05 2013-10-23 盐城师范学院 一种碱性离子液体催化酯交换反应的方法
CN104892608B (zh) * 2015-06-29 2017-06-20 山西康宝生物制品股份有限公司 一种米氮醇的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3190893A (en) * 1961-02-17 1965-06-22 Kefalas As Method of producing 9, 10-dihydroanthracenes
CH420150A (de) * 1961-12-18 1966-09-15 Siegfried Ag Verfahren zur Herstellung von 10-Aminoalkyl-5,5-dialkylacridanen
NL129434C (da) * 1966-03-12
US3808208A (en) * 1970-02-02 1974-04-30 Dow Chemical Co P-benzodithino(dioxino)(2,3,-b)pyrazines
NL176458C (nl) * 1972-09-23 1985-04-16 Akzo Nv Werkwijze ter bereiding van een farmaceutisch preparaat en werkwijze voor de bereiding van daartoe geschikte actieve stoffen.
DE2457971A1 (de) * 1974-12-07 1976-06-10 Merck Patent Gmbh Verfahren zur herstellung von 2-acyl4-oxo-pyrazino-isochinolin-derivaten

Also Published As

Publication number Publication date
GB1498632A (en) 1978-01-25
FR2260579B1 (da) 1977-07-08
FI57106B (fi) 1980-02-29
DK150144B (da) 1986-12-15
US4254031A (en) 1981-03-03
NL7401807A (nl) 1975-08-12
SE418745B (sv) 1981-06-22
JPS50108299A (da) 1975-08-26
DK32375A (da) 1975-09-29
SE7501365L (da) 1975-08-11
DK150144C (da) 1987-10-19
ES434533A1 (es) 1976-12-01
FR2260579A1 (da) 1975-09-05
DE2505239A1 (de) 1975-08-14
JPS5315520B2 (da) 1978-05-25
FI750327A (da) 1975-08-10
US4025513A (en) 1977-05-24
HU169018B (da) 1976-09-28
CA1084490A (en) 1980-08-26
FI57106C (fi) 1980-06-10
CH613705A5 (da) 1979-10-15
GB1498633A (en) 1978-01-25
DE2505239C2 (da) 1988-11-03

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Legal Events

Date Code Title Description
BC A request for examination has been filed
A85 Still pending on 85-01-01