NL176072C - PROCESS FOR THE PREPARATION OF 2-ALKYL 5-THIAZOLIC CARBONIC ACID ESTERS, AND A MEDICINAL PRODUCT WITH DEVASTATIC ACTION; FORMED MEDICINAL PRODUCT. - Google Patents

PROCESS FOR THE PREPARATION OF 2-ALKYL 5-THIAZOLIC CARBONIC ACID ESTERS, AND A MEDICINAL PRODUCT WITH DEVASTATIC ACTION; FORMED MEDICINAL PRODUCT.

Info

Publication number
NL176072C
NL176072C NLAANVRAGE7208138,A NL7208138A NL176072C NL 176072 C NL176072 C NL 176072C NL 7208138 A NL7208138 A NL 7208138A NL 176072 C NL176072 C NL 176072C
Authority
NL
Netherlands
Prior art keywords
medicinal product
devastatic
thiazolic
alkyl
preparation
Prior art date
Application number
NLAANVRAGE7208138,A
Other languages
Dutch (nl)
Other versions
NL176072B (en
NL7208138A (en
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of NL7208138A publication Critical patent/NL7208138A/xx
Publication of NL176072B publication Critical patent/NL176072B/en
Application granted granted Critical
Publication of NL176072C publication Critical patent/NL176072C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
NLAANVRAGE7208138,A 1971-06-14 1972-06-14 PROCESS FOR THE PREPARATION OF 2-ALKYL 5-THIAZOLIC CARBONIC ACID ESTERS, AND A MEDICINAL PRODUCT WITH DEVASTATIC ACTION; FORMED MEDICINAL PRODUCT. NL176072C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7121466A FR2141526B1 (en) 1971-06-14 1971-06-14
FR7306847A FR2247243B2 (en) 1971-06-14 1973-02-27

Publications (3)

Publication Number Publication Date
NL7208138A NL7208138A (en) 1972-12-18
NL176072B NL176072B (en) 1984-09-17
NL176072C true NL176072C (en) 1985-02-18

Family

ID=26216449

Family Applications (2)

Application Number Title Priority Date Filing Date
NLAANVRAGE7208138,A NL176072C (en) 1971-06-14 1972-06-14 PROCESS FOR THE PREPARATION OF 2-ALKYL 5-THIAZOLIC CARBONIC ACID ESTERS, AND A MEDICINAL PRODUCT WITH DEVASTATIC ACTION; FORMED MEDICINAL PRODUCT.
NL7908300A NL7908300A (en) 1971-06-14 1979-11-13 METHOD FOR PREPARING NEW PIPERAZINO-ETHANOL COMPOUNDS.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL7908300A NL7908300A (en) 1971-06-14 1979-11-13 METHOD FOR PREPARING NEW PIPERAZINO-ETHANOL COMPOUNDS.

Country Status (10)

Country Link
US (1) US3853875A (en)
JP (1) JPS5519251A (en)
AT (1) AT317895B (en)
BE (1) BE784777A (en)
CA (1) CA1001629A (en)
CH (1) CH555362A (en)
FR (2) FR2141526B1 (en)
GB (1) GB1382887A (en)
NL (2) NL176072C (en)
SE (1) SE389673B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411900A (en) * 1980-01-03 1983-10-25 Fujisawa Pharmaceutical Co., Ltd. Benzhydrylpiperozinyl thiazole derivatives and pharmaceutical composition comprising the same
DE3002989A1 (en) * 1980-01-29 1981-07-30 Hoechst Ag, 6000 Frankfurt HYDROXYPHENYL-THIAZOLE, -THIAZOLINE AND -THIAZOLIDINE-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR INFLUENCING COLLAGEN METABOLISM
DE4339617C2 (en) * 1993-11-20 2003-06-05 Vortex Gmbh Dt Check valve for a domestic water circulation system
US6083966A (en) 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
EP1143951A3 (en) 1998-09-21 2002-02-06 University Of Florida Research Foundation, Inc. Antimalarial agents
WO2005034949A1 (en) 2003-09-09 2005-04-21 University Of Florida Desferrithiocin derivatives and their use as iron chelators
ES2732625T3 (en) 2005-04-04 2019-11-25 Univ Florida Desferritiocin polyether analogs
AU2008229472B2 (en) 2007-03-15 2013-03-14 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
CN113398126A (en) 2011-12-16 2021-09-17 佛罗里达大学研究基金会 Use of 4' -deferthionin analogues
AU2014352780A1 (en) 2013-11-22 2016-06-09 University Of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
US10570104B2 (en) 2015-04-27 2020-02-25 University Of Florida Research Foundation, Incorporated Metabolically programmed metal chelators and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238203A (en) * 1962-10-12 1966-03-01 Olin Mathieson Basic esters of n-alkenoylanthranilic acid
FR2073284B1 (en) * 1969-12-23 1973-07-13 Ferlux

Also Published As

Publication number Publication date
JPS5519251A (en) 1980-02-09
FR2141526B1 (en) 1975-05-30
DE2228805A1 (en) 1972-12-21
NL176072B (en) 1984-09-17
DE2228805B2 (en) 1977-03-31
NL7908300A (en) 1980-03-31
CH555362A (en) 1974-10-31
AT317895B (en) 1974-09-25
FR2141526A1 (en) 1973-01-26
GB1382887A (en) 1975-02-05
CA1001629A (en) 1976-12-14
US3853875A (en) 1974-12-10
BE784777A (en) 1972-12-13
FR2247243A2 (en) 1975-05-09
SE389673B (en) 1976-11-15
NL7208138A (en) 1972-12-18
FR2247243B2 (en) 1976-12-03

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BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee
V1 Lapsed because of non-payment of the annual fee