FR2141526B1 - - Google Patents

Info

Publication number
FR2141526B1
FR2141526B1 FR7121466A FR7121466A FR2141526B1 FR 2141526 B1 FR2141526 B1 FR 2141526B1 FR 7121466 A FR7121466 A FR 7121466A FR 7121466 A FR7121466 A FR 7121466A FR 2141526 B1 FR2141526 B1 FR 2141526B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7121466A
Other languages
French (fr)
Other versions
FR2141526A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7121466A priority Critical patent/FR2141526B1/fr
Priority to IL39611A priority patent/IL39611A/en
Priority to SU1792313A priority patent/SU465007A3/en
Priority to DD16358272A priority patent/DD99799A5/xx
Priority to CH871872A priority patent/CH555362A/en
Priority to HURO000664 priority patent/HU163928B/hu
Priority to CA144,628A priority patent/CA1001629A/en
Priority to DE19722228805 priority patent/DE2228805C3/en
Priority to BE784777A priority patent/BE784777A/en
Priority to SE7207750A priority patent/SE389673B/en
Priority to ES403786A priority patent/ES403786A1/en
Priority to GB2789372A priority patent/GB1382887A/en
Priority to JP5869472A priority patent/JPS5515477B1/ja
Priority to ZA724090A priority patent/ZA724090B/en
Priority to NLAANVRAGE7208138,A priority patent/NL176072C/en
Priority to AT510672A priority patent/AT317895B/en
Priority to US00262785A priority patent/US3853875A/en
Priority to DK295272A priority patent/DK145224C/en
Publication of FR2141526A1 publication Critical patent/FR2141526A1/fr
Priority to FR7306847A priority patent/FR2247243B2/fr
Application granted granted Critical
Publication of FR2141526B1 publication Critical patent/FR2141526B1/fr
Priority to JP7313379A priority patent/JPS5519251A/en
Priority to NL7908300A priority patent/NL7908300A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
FR7121466A 1971-06-14 1971-06-14 Expired FR2141526B1 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR7121466A FR2141526B1 (en) 1971-06-14 1971-06-14
IL39611A IL39611A (en) 1971-06-14 1972-06-06 New omega-(4-substituted-1-piperazinyl)alkyl esters of 2-alkyl-thiazole-5-carboxylic acids and process for preparing them
SU1792313A SU465007A3 (en) 1971-06-14 1972-06-09 Method for producing 2-alkylthiazole-5-carboxylic acid esters
DD16358272A DD99799A5 (en) 1971-06-14 1972-06-09
CH871872A CH555362A (en) 1971-06-14 1972-06-12 PROCESS FOR THE PREPARATION OF NEW ESTERS OF 2-ALCOYL THIAZOLE 5-CARBOXYLIC ACID.
CA144,628A CA1001629A (en) 1971-06-14 1972-06-13 Process for making new esters from 2-alcoylthiazozol 5-carboxilic acid
DE19722228805 DE2228805C3 (en) 1971-06-14 1972-06-13 Substituted piperazinoethyl esters of 2-propylthiazole-5-carboxylic acid, process for their preparation and pharmaceutical compositions
BE784777A BE784777A (en) 1971-06-14 1972-06-13 NEW ESTERS OF 2-ALCOYL THIAZOL 5-CARBOXYLIC ACID AND PREPARATION PROCESS
SE7207750A SE389673B (en) 1971-06-14 1972-06-13 METHOD OF MAKING NEW ESTERS OF 2-ALKYLTIAZOLE-5-CARBOXYIC ACID
ES403786A ES403786A1 (en) 1971-06-14 1972-06-13 A procedure for the preparation of new esters of the 2-alcohil-tiazol-5-carboxylic acid. (Machine-translation by Google Translate, not legally binding)
HURO000664 HU163928B (en) 1971-06-14 1972-06-13
NLAANVRAGE7208138,A NL176072C (en) 1971-06-14 1972-06-14 PROCESS FOR THE PREPARATION OF 2-ALKYL 5-THIAZOLIC CARBONIC ACID ESTERS, AND A MEDICINAL PRODUCT WITH DEVASTATIC ACTION; FORMED MEDICINAL PRODUCT.
ZA724090A ZA724090B (en) 1971-06-14 1972-06-14 New esters of 2-alkyl thiazole 5-carboxylic acid and process for preparing them
GB2789372A GB1382887A (en) 1971-06-14 1972-06-14 Thiazole-5-carboxylic acid esters
AT510672A AT317895B (en) 1971-06-14 1972-06-14 Process for the preparation of new esters of 2-alkyl-thiazole-5-carboxylic acid and their acid addition salts
US00262785A US3853875A (en) 1971-06-14 1972-06-14 Esters of 2-alkyl thiazole 5-carboxylic acid
DK295272A DK145224C (en) 1971-06-14 1972-06-14 METHOD OF ANALOGUE FOR PREPARING ESTERS OF 2-ALKYLTHIAZOL-5-CARBOXYLIC ACID OR SALTS THEREOF
JP5869472A JPS5515477B1 (en) 1971-06-14 1972-06-14
FR7306847A FR2247243B2 (en) 1971-06-14 1973-02-27
JP7313379A JPS5519251A (en) 1971-06-14 1979-06-12 Manufacture of substituted piperazinoethanol
NL7908300A NL7908300A (en) 1971-06-14 1979-11-13 METHOD FOR PREPARING NEW PIPERAZINO-ETHANOL COMPOUNDS.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7121466A FR2141526B1 (en) 1971-06-14 1971-06-14
FR7306847A FR2247243B2 (en) 1971-06-14 1973-02-27

Publications (2)

Publication Number Publication Date
FR2141526A1 FR2141526A1 (en) 1973-01-26
FR2141526B1 true FR2141526B1 (en) 1975-05-30

Family

ID=26216449

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7121466A Expired FR2141526B1 (en) 1971-06-14 1971-06-14
FR7306847A Expired FR2247243B2 (en) 1971-06-14 1973-02-27

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7306847A Expired FR2247243B2 (en) 1971-06-14 1973-02-27

Country Status (10)

Country Link
US (1) US3853875A (en)
JP (1) JPS5519251A (en)
AT (1) AT317895B (en)
BE (1) BE784777A (en)
CA (1) CA1001629A (en)
CH (1) CH555362A (en)
FR (2) FR2141526B1 (en)
GB (1) GB1382887A (en)
NL (2) NL176072C (en)
SE (1) SE389673B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411900A (en) * 1980-01-03 1983-10-25 Fujisawa Pharmaceutical Co., Ltd. Benzhydrylpiperozinyl thiazole derivatives and pharmaceutical composition comprising the same
DE3002989A1 (en) * 1980-01-29 1981-07-30 Hoechst Ag, 6000 Frankfurt HYDROXYPHENYL-THIAZOLE, -THIAZOLINE AND -THIAZOLIDINE-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR INFLUENCING COLLAGEN METABOLISM
DE4339617C2 (en) * 1993-11-20 2003-06-05 Vortex Gmbh Dt Check valve for a domestic water circulation system
US6083966A (en) 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
EP1143951A3 (en) 1998-09-21 2002-02-06 University Of Florida Research Foundation, Inc. Antimalarial agents
AU2003270473A1 (en) 2003-09-09 2005-04-27 University Of Florida Desferrithiocin derivatives and their use as iron chelators
EP1866296B1 (en) 2005-04-04 2016-11-02 University of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
NZ579994A (en) 2007-03-15 2011-09-30 Univ Florida Desferrithiocin polyether analogues useful in the treatment of pathological conditions responsive to chelation or sequestration of trivalent metal
ES2761200T3 (en) 2011-12-16 2020-05-19 Univ Florida Uses of 4'-deferritiocin analogs
EP3071201A4 (en) 2013-11-22 2017-04-26 University of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
CA2984250A1 (en) 2015-04-27 2016-11-03 University Of Florida Research Foundation, Incorporated Metabolically programmed metal chelators and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238203A (en) * 1962-10-12 1966-03-01 Olin Mathieson Basic esters of n-alkenoylanthranilic acid
FR2073284B1 (en) * 1969-12-23 1973-07-13 Ferlux

Also Published As

Publication number Publication date
NL7908300A (en) 1980-03-31
FR2247243A2 (en) 1975-05-09
DE2228805B2 (en) 1977-03-31
US3853875A (en) 1974-12-10
DE2228805A1 (en) 1972-12-21
CA1001629A (en) 1976-12-14
JPS5519251A (en) 1980-02-09
SE389673B (en) 1976-11-15
NL176072B (en) 1984-09-17
AT317895B (en) 1974-09-25
FR2141526A1 (en) 1973-01-26
GB1382887A (en) 1975-02-05
NL176072C (en) 1985-02-18
NL7208138A (en) 1972-12-18
FR2247243B2 (en) 1976-12-03
BE784777A (en) 1972-12-13
CH555362A (en) 1974-10-31

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Legal Events

Date Code Title Description
ST Notification of lapse