NL173407B - Werkwijze ter bereiding van 3-(nucleofielmethyl)deltaÿ3-cefemverbindingen. - Google Patents

Werkwijze ter bereiding van 3-(nucleofielmethyl)deltaÿ3-cefemverbindingen.

Info

Publication number
NL173407B
NL173407B NLAANVRAGE6902013,A NL6902013A NL173407B NL 173407 B NL173407 B NL 173407B NL 6902013 A NL6902013 A NL 6902013A NL 173407 B NL173407 B NL 173407B
Authority
NL
Netherlands
Prior art keywords
nucleophyl
deltaÿ3
methyl
preparing
cefem compounds
Prior art date
Application number
NLAANVRAGE6902013,A
Other languages
English (en)
Other versions
NL6902013A (nl
NL173407C (nl
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NL6902013A publication Critical patent/NL6902013A/xx
Publication of NL173407B publication Critical patent/NL173407B/nl
Application granted granted Critical
Publication of NL173407C publication Critical patent/NL173407C/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/60Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 3 and 4
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
NLAANVRAGE6902013,A 1968-02-07 1969-02-07 Werkwijze ter bereiding van 3-(nucleofielmethyl)deltaÿ3-cefemverbindingen. NL173407C (nl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70352368A 1968-02-07 1968-02-07
US79088669A 1969-01-13 1969-01-13
US79084269A 1969-01-13 1969-01-13

Publications (3)

Publication Number Publication Date
NL6902013A NL6902013A (nl) 1969-08-11
NL173407B true NL173407B (nl) 1983-08-16
NL173407C NL173407C (nl) 1984-01-16

Family

ID=27418758

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE6902013,A NL173407C (nl) 1968-02-07 1969-02-07 Werkwijze ter bereiding van 3-(nucleofielmethyl)deltaÿ3-cefemverbindingen.

Country Status (11)

Country Link
JP (3) JPS524558B1 (nl)
BE (1) BE728053A (nl)
CH (1) CH534694A (nl)
DK (1) DK140726B (nl)
FI (1) FI56535C (nl)
FR (3) FR2001491B1 (nl)
GB (2) GB1265333A (nl)
IL (2) IL40447A (nl)
LU (1) LU57932A1 (nl)
NL (1) NL173407C (nl)
SE (3) SE384511B (nl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2132883A1 (de) * 1970-07-08 1972-01-13 Ciba Geigy Ag Cephemverbindungen
JPS53164082U (nl) * 1977-05-31 1978-12-22
JPS5899787U (ja) * 1981-12-28 1983-07-07 奥野電器株式会社 ランプ用ソケツト
EP0300546B1 (en) * 1987-07-10 1995-08-09 Gist-Brocades N.V. Process for the preparation of cephem compounds and cephalosporin derivatives

Also Published As

Publication number Publication date
SE384511B (sv) 1976-05-10
FR2085656A1 (nl) 1971-12-31
FI56535C (fi) 1980-02-11
SE7512818L (sv) 1975-11-14
DK140726B (da) 1979-11-05
FR2085656B1 (nl) 1974-08-23
NL6902013A (nl) 1969-08-11
JPS524559B1 (nl) 1977-02-04
FR2001491A1 (nl) 1969-09-26
SE407064B (sv) 1979-03-12
BE728053A (nl) 1969-08-07
CH534694A (de) 1973-03-15
DK140726C (nl) 1980-03-31
JPS524558B1 (nl) 1977-02-04
GB1265333A (nl) 1972-03-01
LU57932A1 (nl) 1969-09-17
SE418616B (sv) 1981-06-15
NL173407C (nl) 1984-01-16
FR2095486A5 (nl) 1972-02-11
JPS4924076B1 (nl) 1974-06-20
GB1265332A (nl) 1972-03-01
FI56535B (fi) 1979-10-31
IL41553A (en) 1976-02-29
IL40447A (en) 1976-02-29
FR2001491B1 (nl) 1973-07-13

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Legal Events

Date Code Title Description
V4 Lapsed because of reaching the maximum lifetime of a patent