NL165158C - Werkwijze ter bereiding van 5-fenyl-1,3-dihydro-1,4- -benzodiazepinederivaten. - Google Patents
Werkwijze ter bereiding van 5-fenyl-1,3-dihydro-1,4- -benzodiazepinederivaten.Info
- Publication number
- NL165158C NL165158C NL6913339.A NL6913339A NL165158C NL 165158 C NL165158 C NL 165158C NL 6913339 A NL6913339 A NL 6913339A NL 165158 C NL165158 C NL 165158C
- Authority
- NL
- Netherlands
- Prior art keywords
- dihydro
- phenyl
- preparing
- benzodiazepine derivatives
- benzodiazepine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C11/00—Component parts, details or accessories not specifically provided for in groups B05C1/00 - B05C9/00
- B05C11/11—Vats or other containers for liquids or other fluent materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D3/00—Cutting work characterised by the nature of the cut made; Apparatus therefor
- B26D3/18—Cutting work characterised by the nature of the cut made; Apparatus therefor to obtain cubes or the like
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Forests & Forestry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Mechanical Engineering (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6332468 | 1968-09-03 | ||
| JP6332368 | 1968-09-03 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL6913339A NL6913339A (xx) | 1970-03-05 |
| NL165158B NL165158B (nl) | 1980-10-15 |
| NL165158C true NL165158C (nl) | 1981-03-16 |
Family
ID=26404426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL6913339.A NL165158C (nl) | 1968-09-03 | 1969-09-01 | Werkwijze ter bereiding van 5-fenyl-1,3-dihydro-1,4- -benzodiazepinederivaten. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3692772A (xx) |
| CH (1) | CH535243A (xx) |
| DE (2) | DE1966132B2 (xx) |
| ES (1) | ES371134A1 (xx) |
| FR (1) | FR2017275B1 (xx) |
| GB (2) | GB1276168A (xx) |
| NL (1) | NL165158C (xx) |
| NO (1) | NO124035B (xx) |
| SE (1) | SE349807B (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1484661A (en) * | 1975-01-06 | 1977-09-01 | Clin Midy | Preparatin of benzodiazepine derivatives |
| CN110003125A (zh) * | 2019-04-24 | 2019-07-12 | 湖北美林药业有限公司 | 一种地西泮、地西泮注射液及其制备方法 |
| CN114276375A (zh) * | 2021-12-15 | 2022-04-05 | 重庆医科大学 | 一种1,3,2-苯并二氮杂硼烷酮及其衍生物的合成方法 |
| CN115197261B (zh) * | 2022-07-06 | 2024-05-03 | 重庆医科大学 | 噁二氮杂硼衍生物的合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1411072A (fr) * | 1963-07-10 | 1965-09-17 | Hoffmann La Roche | Procédé pour la préparation de dérivés de benzodiazépine |
| NL6409554A (xx) * | 1964-08-19 | 1966-02-21 | ||
| US3558603A (en) * | 1967-12-01 | 1971-01-26 | Sumitomo Chemical Co | Process for producing benzodiazepine derivatives |
-
1969
- 1969-08-25 SE SE11770/69A patent/SE349807B/xx unknown
- 1969-09-01 NL NL6913339.A patent/NL165158C/xx not_active IP Right Cessation
- 1969-09-02 CH CH1327869A patent/CH535243A/de not_active IP Right Cessation
- 1969-09-02 ES ES371134A patent/ES371134A1/es not_active Expired
- 1969-09-02 DE DE1966132A patent/DE1966132B2/de not_active Withdrawn
- 1969-09-02 FR FR696929938A patent/FR2017275B1/fr not_active Expired
- 1969-09-02 DE DE1944404A patent/DE1944404C3/de not_active Expired
- 1969-09-02 NO NO3505/69A patent/NO124035B/no unknown
- 1969-09-03 US US855042A patent/US3692772A/en not_active Expired - Lifetime
- 1969-09-03 GB GB43519/69A patent/GB1276168A/en not_active Expired
- 1969-09-03 GB GB34002/71A patent/GB1276169A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3692772A (en) | 1972-09-19 |
| NL165158B (nl) | 1980-10-15 |
| DE1966132A1 (de) | 1971-08-19 |
| FR2017275A1 (xx) | 1970-05-22 |
| CH535243A (de) | 1973-03-31 |
| NO124035B (xx) | 1972-02-21 |
| FR2017275B1 (xx) | 1973-06-08 |
| ES371134A1 (es) | 1972-01-01 |
| DE1944404B2 (de) | 1979-01-11 |
| NL6913339A (xx) | 1970-03-05 |
| DE1944404C3 (de) | 1979-09-13 |
| GB1276169A (en) | 1972-06-01 |
| GB1276168A (en) | 1972-06-01 |
| DE1966132B2 (de) | 1981-07-23 |
| DE1944404A1 (de) | 1970-03-12 |
| SE349807B (xx) | 1972-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| V1 | Lapsed because of non-payment of the annual fee |