FR2017275B1 - - Google Patents

Info

Publication number
FR2017275B1
FR2017275B1 FR696929938A FR6929938A FR2017275B1 FR 2017275 B1 FR2017275 B1 FR 2017275B1 FR 696929938 A FR696929938 A FR 696929938A FR 6929938 A FR6929938 A FR 6929938A FR 2017275 B1 FR2017275 B1 FR 2017275B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR696929938A
Other versions
FR2017275A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FR2017275A1 publication Critical patent/FR2017275A1/fr
Application granted granted Critical
Publication of FR2017275B1 publication Critical patent/FR2017275B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05CAPPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C11/00Component parts, details or accessories not specifically provided for in groups B05C1/00 - B05C9/00
    • B05C11/11Vats or other containers for liquids or other fluent materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B26HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26DCUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D3/00Cutting work characterised by the nature of the cut made; Apparatus therefor
    • B26D3/18Cutting work characterised by the nature of the cut made; Apparatus therefor to obtain cubes or the like
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/26Preparation from compounds already containing the benzodiazepine skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Forests & Forestry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mechanical Engineering (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR696929938A 1968-09-03 1969-09-02 Expired FR2017275B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6332368 1968-09-03
JP6332468 1968-09-03

Publications (2)

Publication Number Publication Date
FR2017275A1 FR2017275A1 (fr) 1970-05-22
FR2017275B1 true FR2017275B1 (fr) 1973-06-08

Family

ID=26404426

Family Applications (1)

Application Number Title Priority Date Filing Date
FR696929938A Expired FR2017275B1 (fr) 1968-09-03 1969-09-02

Country Status (9)

Country Link
US (1) US3692772A (fr)
CH (1) CH535243A (fr)
DE (2) DE1966132B2 (fr)
ES (1) ES371134A1 (fr)
FR (1) FR2017275B1 (fr)
GB (2) GB1276169A (fr)
NL (1) NL165158C (fr)
NO (1) NO124035B (fr)
SE (1) SE349807B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1484661A (en) * 1975-01-06 1977-09-01 Clin Midy Preparatin of benzodiazepine derivatives
CN110003125A (zh) * 2019-04-24 2019-07-12 湖北美林药业有限公司 一种地西泮、地西泮注射液及其制备方法
CN114276375A (zh) * 2021-12-15 2022-04-05 重庆医科大学 一种1,3,2-苯并二氮杂硼烷酮及其衍生物的合成方法
CN115197261B (zh) * 2022-07-06 2024-05-03 重庆医科大学 噁二氮杂硼衍生物的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1411072A (fr) * 1963-07-10 1965-09-17 Hoffmann La Roche Procédé pour la préparation de dérivés de benzodiazépine
NL6409554A (fr) * 1964-08-19 1966-02-21
US3558603A (en) * 1967-12-01 1971-01-26 Sumitomo Chemical Co Process for producing benzodiazepine derivatives

Also Published As

Publication number Publication date
GB1276169A (en) 1972-06-01
DE1944404B2 (de) 1979-01-11
FR2017275A1 (fr) 1970-05-22
DE1944404A1 (de) 1970-03-12
SE349807B (fr) 1972-10-09
GB1276168A (en) 1972-06-01
ES371134A1 (es) 1972-01-01
DE1966132A1 (de) 1971-08-19
NL165158B (nl) 1980-10-15
US3692772A (en) 1972-09-19
NL165158C (nl) 1981-03-16
NO124035B (fr) 1972-02-21
DE1944404C3 (de) 1979-09-13
CH535243A (de) 1973-03-31
DE1966132B2 (de) 1981-07-23
NL6913339A (fr) 1970-03-05

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Legal Events

Date Code Title Description
ST Notification of lapse