NL158779B - Werkwijze ter bereiding van een farmaceutisch preparaat met cholesterolspiegel verlagende werking en van een verbinding, die gebruikt kan worden in zo'n preparaat. - Google Patents
Werkwijze ter bereiding van een farmaceutisch preparaat met cholesterolspiegel verlagende werking en van een verbinding, die gebruikt kan worden in zo'n preparaat.Info
- Publication number
- NL158779B NL158779B NL6708766.A NL6708766A NL158779B NL 158779 B NL158779 B NL 158779B NL 6708766 A NL6708766 A NL 6708766A NL 158779 B NL158779 B NL 158779B
- Authority
- NL
- Netherlands
- Prior art keywords
- preparation
- preparing
- compound
- reducing action
- pharmaceutical preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
- C07C17/2637—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions between a compound containing only oxygen and possibly halogen as hetero-atoms and a halogenated hydrocarbon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/22—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/19—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB28198/66A GB1140748A (en) | 1966-06-23 | 1966-06-23 | New carboxylic acid derivatives |
GB2820066 | 1966-06-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
NL6708766A NL6708766A (nl) | 1967-12-27 |
NL158779B true NL158779B (nl) | 1978-12-15 |
Family
ID=26259251
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL6708766.A NL158779B (nl) | 1966-06-23 | 1967-06-23 | Werkwijze ter bereiding van een farmaceutisch preparaat met cholesterolspiegel verlagende werking en van een verbinding, die gebruikt kan worden in zo'n preparaat. |
Country Status (10)
Country | Link |
---|---|
US (1) | US3549690A (nl) |
BE (1) | BE700110A (nl) |
CH (1) | CH506467A (nl) |
DE (1) | DE1618568B2 (nl) |
DK (1) | DK117823B (nl) |
FR (1) | FR8486M (nl) |
GB (1) | GB1140748A (nl) |
MY (1) | MY7300061A (nl) |
NL (1) | NL158779B (nl) |
SE (1) | SE343572B (nl) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7416412A (nl) * | 1973-12-27 | 1975-07-01 | Siegfried Ag | Werkwijze ter bereiding van nieuwe cholesterol- gende verbindingen. |
AT336589B (de) * | 1974-05-20 | 1977-05-10 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen biphenylderivaten |
US4107329A (en) * | 1974-12-06 | 1978-08-15 | Imperial Chemical Industries Limited | Fluorinated compounds as therapeutics |
GB1499508A (en) * | 1974-12-06 | 1978-02-01 | Ici Ltd | 3,3,3-trifluoropropionic acid derivatives |
ATE1855T1 (de) * | 1978-09-08 | 1982-12-15 | Imperial Chemical Industries Plc | Antiarthritische hydroxyessigsaeurederivate, pharmazeutische zusammensetzungen daraus und verfahren zu ihrer herstellung. |
US4214004A (en) * | 1978-12-04 | 1980-07-22 | Fmc Corporation | Insecticidal cyclopropanecarboxylates from substituted [1,1'-biphenyl]-3-ylmethyl compounds |
GB2073177A (en) * | 1980-04-03 | 1981-10-14 | Ici Ltd | Benzaldehyde derivative |
JPS58150563A (ja) * | 1982-03-04 | 1983-09-07 | Taisho Pharmaceut Co Ltd | 3−ベンゾイル−2−メルカプトプロピオン酸誘導体 |
US4864038A (en) * | 1986-05-05 | 1989-09-05 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
IL94466A (en) * | 1989-05-25 | 1995-01-24 | Erba Carlo Spa | Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation |
US5307735A (en) * | 1992-11-05 | 1994-05-03 | Gross-Given Manufacturing Co. | Beverage brewing device |
GB9306899D0 (en) * | 1993-04-01 | 1993-05-26 | Erba Carlo Spa | Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation |
GB9306886D0 (en) * | 1993-04-01 | 1993-05-26 | Erba Carlo Spa | Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation |
GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
JP2002516855A (ja) | 1998-06-02 | 2002-06-11 | アースロミックス・パブリック・リミテッド・カンパニー | 繊維症治療用の甲状腺ホルモン受容体と相互作用する化合物 |
PT1423168E (pt) | 2001-09-03 | 2006-05-31 | Newron Pharm Spa | Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico |
EP1438956A1 (en) * | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
AR044007A1 (es) | 2003-04-11 | 2005-08-24 | Newron Pharmaceuticals Inc | Metodos para el tratamiento de la enfermedad de parkinson |
US7449481B2 (en) * | 2004-04-13 | 2008-11-11 | Cephalon, Inc. | Thio-substituted biaryl-methanesulfinyl derivatives |
EP1586559A1 (en) * | 2004-04-13 | 2005-10-19 | Cephalon, Inc. | Biaryl-methanethio-, -sulphinyl- and sulphonyl derivatives |
EP1588704A1 (en) | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders |
RU2391973C2 (ru) * | 2004-09-10 | 2010-06-20 | Ньюрон Фармасьютикалс С.П.А. | Применение (галобензилокси)бензиламино-пропанамидов для производства лекарственных средств, действующих как селективные модуляторы натриевых и/или кальциевых каналов |
EP1870097A1 (en) | 2006-06-15 | 2007-12-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of cognitive disorders |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3332842A (en) * | 1963-08-30 | 1967-07-25 | Ciba Geigy Corp | Ether acids and derivatives thereof |
US3364249A (en) * | 1964-01-30 | 1968-01-16 | Merck & Co Inc | N-carboxyalkyl-phenoxyalkanoic acid amide |
-
1966
- 1966-06-23 GB GB28198/66A patent/GB1140748A/en not_active Expired
-
1967
- 1967-06-08 US US644489A patent/US3549690A/en not_active Expired - Lifetime
- 1967-06-14 DE DE1967J0033909 patent/DE1618568B2/de active Granted
- 1967-06-16 BE BE700110D patent/BE700110A/xx not_active IP Right Cessation
- 1967-06-20 DK DK318767AA patent/DK117823B/da not_active IP Right Cessation
- 1967-06-21 SE SE8887/67A patent/SE343572B/xx unknown
- 1967-06-22 CH CH884567A patent/CH506467A/de not_active IP Right Cessation
- 1967-06-23 NL NL6708766.A patent/NL158779B/nl not_active IP Right Cessation
- 1967-09-22 FR FR122014A patent/FR8486M/fr not_active Expired
-
1973
- 1973-12-31 MY MY197361A patent/MY7300061A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DK117823B (da) | 1970-06-08 |
US3549690A (en) | 1970-12-22 |
DE1618568A1 (de) | 1971-02-25 |
CH506467A (de) | 1971-04-30 |
MY7300061A (en) | 1973-12-31 |
DE1618568B2 (de) | 1976-07-01 |
SE343572B (nl) | 1972-03-13 |
GB1140748A (en) | 1969-01-22 |
FR8486M (nl) | 1973-07-27 |
BE700110A (nl) | 1967-12-18 |
NL6708766A (nl) | 1967-12-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
V1 | Lapsed because of non-payment of the annual fee | ||
NL80 | Information provided on patent owner name for an already discontinued patent |
Owner name: ICI |