MY7100120A - Basically substituted bis-benzimidazole ds and process for their manufacture - Google Patents
Basically substituted bis-benzimidazole ds and process for their manufactureInfo
- Publication number
- MY7100120A MY7100120A MY1971120A MY7100120A MY7100120A MY 7100120 A MY7100120 A MY 7100120A MY 1971120 A MY1971120 A MY 1971120A MY 7100120 A MY7100120 A MY 7100120A MY 7100120 A MY7100120 A MY 7100120A
- Authority
- MY
- Malaysia
- Prior art keywords
- benzimidazole
- manufacture
- substituted bis
- basically substituted
- basically
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- INAAIJLSXJJHOZ-UHFFFAOYSA-N pibenzimol Chemical class C1CN(C)CCN1C1=CC=C(N=C(N2)C=3C=C4NC(=NC4=CC=3)C=3C=CC(O)=CC=3)C2=C1 INAAIJLSXJJHOZ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF0048833 | 1966-04-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY7100120A true MY7100120A (en) | 1971-12-31 |
Family
ID=7102516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MY1971120A MY7100120A (en) | 1966-04-01 | 1971-12-31 | Basically substituted bis-benzimidazole ds and process for their manufacture |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3538097A (cs) |
| BE (1) | BE696499A (cs) |
| CH (2) | CH525902A (cs) |
| DE (1) | DE1670684A1 (cs) |
| FR (2) | FR1519964A (cs) |
| GB (1) | GB1186723A (cs) |
| MY (1) | MY7100120A (cs) |
| NL (1) | NL6704539A (cs) |
| OA (1) | OA02583A (cs) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091101A (en) * | 1977-06-15 | 1978-05-23 | Merck & Co., Inc. | 6-(1-Piperazinyl)quinoxaline |
| DE3611343A1 (de) * | 1986-04-04 | 1987-10-08 | Boehringer Mannheim Gmbh | Heterocyclisch substituierte benzimidazole, verfahren zu ihrer herstellung, arzneimittel sowie zwischenprodukte |
| AU695936B2 (en) * | 1994-08-26 | 1998-08-27 | Auckland Division Cancer Society Of New Zealand Inc | Novel dna-targeted alkylating agents |
| EP0777656B1 (en) * | 1994-08-26 | 2004-04-14 | Auckland Division Cancer Society Of New Zealand (Incorporated) | Novel dna-targeted alkylating agents |
| US5807874A (en) * | 1995-05-17 | 1998-09-15 | Rutgers, The State University Of New Jersey | Trisbenzimidazoles useful as topoisomerase I inhibitors |
| US5767142A (en) * | 1996-03-20 | 1998-06-16 | Rutgers, The State University Of New Jersey | Trisbenzimidazoles useful as topoisomerase I inhibitors |
| AUPN449295A0 (en) * | 1995-07-28 | 1995-08-24 | Inner And Eastern Health Care Network, The | Radioprotectors |
| PL332416A1 (en) * | 1996-09-23 | 1999-09-13 | Rutgers | Substituted heterocyclic compounds as anticarcinogenic agents |
| US6140328A (en) | 1997-12-12 | 2000-10-31 | Rutgers, The State University Of New Jersey | Heterocyclic cytotoxic agents |
| DE69839781D1 (en) * | 1997-12-31 | 2008-09-04 | Univ Rutgers | Heterocyclische topoisomerase toxine |
| US6063801A (en) | 1998-02-12 | 2000-05-16 | Rutgers, The State University Of New Jersey | Heterocyclic topoisomerase poisons |
| US6740650B2 (en) | 1999-10-29 | 2004-05-25 | Rutgers, The State University Of New Jersey | Heterocyclic cytotoxic agents |
| DE60231426D1 (de) * | 2001-11-14 | 2009-04-16 | Univ Rutgers | Solubilisierte topoisomerase-gift-mittel |
| EP1465625B1 (en) * | 2001-11-14 | 2010-02-03 | Rutgers, The State University | Solubilized topoisomerase poisons |
| AU2002352708A1 (en) | 2001-11-14 | 2003-05-26 | Edmond J. Lavoie | Cytotoxic agents |
| ATE390923T1 (de) * | 2001-11-14 | 2008-04-15 | Univ Rutgers | Topoisomerase-giftmittel |
| US20050119251A1 (en) * | 2001-12-21 | 2005-06-02 | Jian-Min Fu | Nicotinamide derivatives and their use as therapeutic agents |
| WO2004014906A2 (en) * | 2002-08-09 | 2004-02-19 | Rutgers, The State University | Nitro and amino substituted dibenzonaphthyridines as topoisomerase agents |
| AU2003265405A1 (en) * | 2002-08-09 | 2004-02-25 | Edmond J. Lavoie | Nitro and amino substituted heterocycles as topoisomerase i targeting agents |
| WO2004014918A1 (en) | 2002-08-09 | 2004-02-19 | Rutgers, The State University | Nitro and amino substituted topoisomerase agents |
| WO2004044174A2 (en) * | 2002-11-12 | 2004-05-27 | Rutgers, The State University | Topoisomerase-targeting agents |
| CN101083993A (zh) * | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途 |
| US8071603B2 (en) | 2004-09-20 | 2011-12-06 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
| EP2540296A1 (en) * | 2005-06-03 | 2013-01-02 | Xenon Pharmaceuticals Inc. | Arminothiazole derivatives as human stearoyl-coa desaturase inhibitors |
| PT2114896E (pt) * | 2006-12-21 | 2015-11-04 | Peter Maccallum Cancer Inst | Compostos radio-protetores e métodos relacionados |
| GB0821913D0 (en) | 2008-12-02 | 2009-01-07 | Price & Co | Antibacterial compounds |
| WO2010102219A1 (en) | 2009-03-06 | 2010-09-10 | Rutgers, The State University Of New Jersey | Methylenedioxybenzo [i] phenanthridine derivatives used to treat cancer |
| WO2010127363A1 (en) | 2009-05-01 | 2010-11-04 | Rutgers, The State University Of New Jersey | Toposiomerase inhibitors |
| JP5712524B2 (ja) * | 2009-10-28 | 2015-05-07 | Jsr株式会社 | 液晶配向剤および液晶表示素子 |
| DK2575968T3 (en) * | 2010-06-01 | 2016-05-30 | Summit Therapeutics Plc | COMPOUNDS FOR THE TREATMENT OF Clostridium difficile-associated disease |
| WO2012170867A1 (en) * | 2011-06-09 | 2012-12-13 | Rhizen Pharmaceuticals Sa | Novel compounds as modulators of gpr-119 |
| GB201506658D0 (en) | 2015-04-20 | 2015-06-03 | Cellcentric Ltd | Pharmaceutical compounds |
| GB201506660D0 (en) | 2015-04-20 | 2015-06-03 | Cellcentric Ltd | Pharmaceutical compounds |
| WO2017125944A1 (en) * | 2016-01-23 | 2017-07-27 | Jawaharlal Nehru University (Jnu) | Broad spectrum antibacterial activity of novel bisbenzimidazoles targeting topoisomerase ia and the synergistic composition of bisbenzimidazole with efflux pump inhibitors against pathogenic bacteria |
| EP3442979A4 (en) | 2016-04-04 | 2019-12-18 | Rutgers, the State University of New Jersey | topoisomerase poisons |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3103403A (en) * | 1963-09-10 | Dyeing of polyester fibers with com- | ||
| US2980690A (en) * | 1957-08-30 | 1961-04-18 | Ciba Pharm Prod Inc | New basically substituted benzylbenzimidazoles |
| US3072661A (en) * | 1960-08-24 | 1963-01-08 | Interchem Corp | New process for improved bis-imidazole vat dyestuff pigments |
| US3133056A (en) * | 1961-05-15 | 1964-05-12 | May & Baker Ltd | N-phenylpiperazine derivatives of tetrahydrobenzodiazepines |
| BE631368A (cs) * | 1962-04-21 | |||
| NL135043C (cs) * | 1963-10-11 | |||
| GB1122988A (en) * | 1964-10-22 | 1968-08-07 | Fisons Pest Control Ltd | Benzimidazole derivatives |
| US3336191A (en) * | 1966-03-11 | 1967-08-15 | Smith Kline French Lab | Anthelmintic 2-amidobenzimidazoles |
| US3362956A (en) * | 1965-08-19 | 1968-01-09 | Sterling Drug Inc | 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines |
-
1966
- 1966-04-01 DE DE19661670684 patent/DE1670684A1/de active Pending
-
1967
- 1967-03-23 US US625329A patent/US3538097A/en not_active Expired - Lifetime
- 1967-03-28 CH CH429167A patent/CH525902A/de not_active IP Right Cessation
- 1967-03-28 CH CH594172A patent/CH533124A/de not_active IP Right Cessation
- 1967-03-30 NL NL6704539A patent/NL6704539A/xx unknown
- 1967-03-30 GB GB04681/67A patent/GB1186723A/en not_active Expired
- 1967-04-01 OA OA52892A patent/OA02583A/xx unknown
- 1967-04-03 FR FR101212A patent/FR1519964A/fr not_active Expired
- 1967-04-03 BE BE696499D patent/BE696499A/xx unknown
- 1967-06-29 FR FR112465A patent/FR6681M/fr not_active Expired
-
1971
- 1971-12-31 MY MY1971120A patent/MY7100120A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH525902A (de) | 1972-07-31 |
| OA02583A (fr) | 1970-05-05 |
| NL6704539A (cs) | 1967-10-02 |
| CH533124A (de) | 1973-01-31 |
| FR6681M (cs) | 1969-02-03 |
| US3538097A (en) | 1970-11-03 |
| BE696499A (cs) | 1967-10-03 |
| DE1670684A1 (de) | 1970-12-03 |
| GB1186723A (en) | 1970-04-02 |
| FR1519964A (fr) | 1968-04-05 |
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