MY132470A - Substituted oxobutyric acids as matrix metalloprotease inhibitors - Google Patents
Substituted oxobutyric acids as matrix metalloprotease inhibitorsInfo
- Publication number
- MY132470A MY132470A MYPI97002045A MYPI19972045A MY132470A MY 132470 A MY132470 A MY 132470A MY PI97002045 A MYPI97002045 A MY PI97002045A MY PI19972045 A MYPI19972045 A MY PI19972045A MY 132470 A MY132470 A MY 132470A
- Authority
- MY
- Malaysia
- Prior art keywords
- matrix metalloprotease
- substituted
- metalloprotease inhibitors
- formula
- carbons
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64838496A | 1996-05-15 | 1996-05-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
MY132470A true MY132470A (en) | 2007-10-31 |
Family
ID=24600568
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MYPI97002045A MY132470A (en) | 1996-05-15 | 1997-05-09 | Substituted oxobutyric acids as matrix metalloprotease inhibitors |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0912487A1 (xx) |
JP (1) | JP3417951B2 (xx) |
CN (1) | CN1163466C (xx) |
AR (1) | AR007096A1 (xx) |
AU (1) | AU727648B2 (xx) |
CA (1) | CA2253869C (xx) |
CO (1) | CO4990925A1 (xx) |
HR (1) | HRP970246B1 (xx) |
ID (1) | ID20291A (xx) |
MY (1) | MY132470A (xx) |
PA (1) | PA8429401A1 (xx) |
PE (1) | PE65998A1 (xx) |
SV (1) | SV1997000034A (xx) |
TN (1) | TNSN97085A1 (xx) |
TW (1) | TW467892B (xx) |
WO (1) | WO1997043238A1 (xx) |
YU (1) | YU18797A (xx) |
ZA (1) | ZA974032B (xx) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6288063B1 (en) | 1998-05-27 | 2001-09-11 | Bayer Corporation | Substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors |
GB0321538D0 (en) | 2003-09-13 | 2003-10-15 | Glaxo Group Ltd | Therapeutically useful compounds |
US20100324081A1 (en) * | 2007-08-15 | 2010-12-23 | Kyorin Pharmaceutical Co., Ltd. | Preventive, inhibitor or remedy for cerebral aneurysm comprising ibudilast as an active ingredient |
EP3126339A1 (de) | 2014-04-03 | 2017-02-08 | Bayer Pharma Aktiengesellschaft | 2,5-disubstituierte cyclopentancarbonsäuren und ihre verwendung |
JP2017509665A (ja) | 2014-04-03 | 2017-04-06 | バイエル ファーマ アクチエンゲゼルシャフト | 気道疾患治療のための2,5−ジ置換されたシクロペンタンカルボン酸類 |
JP2017511319A (ja) | 2014-04-03 | 2017-04-20 | バイエル ファーマ アクチエンゲゼルシャフト | キラル2,5−ジ置換されたシクロペンタンカルボン酸誘導体およびそれの使用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69529100T2 (de) * | 1994-01-22 | 2003-07-17 | British Biotech Pharm | Metalloproteinaseinhibitoren |
-
1997
- 1997-05-09 ZA ZA9704032A patent/ZA974032B/xx unknown
- 1997-05-09 MY MYPI97002045A patent/MY132470A/en unknown
- 1997-05-09 CO CO97025164A patent/CO4990925A1/es unknown
- 1997-05-09 TN TNTNSN97085A patent/TNSN97085A1/fr unknown
- 1997-05-09 HR HR970246A patent/HRP970246B1/xx not_active IP Right Cessation
- 1997-05-12 AR ARP970101976A patent/AR007096A1/es unknown
- 1997-05-12 TW TW086106284A patent/TW467892B/zh not_active IP Right Cessation
- 1997-05-12 PA PA19978429401A patent/PA8429401A1/es unknown
- 1997-05-12 JP JP54100297A patent/JP3417951B2/ja not_active Expired - Fee Related
- 1997-05-12 CN CNB971964599A patent/CN1163466C/zh not_active Expired - Fee Related
- 1997-05-12 AU AU31219/97A patent/AU727648B2/en not_active Ceased
- 1997-05-12 YU YU18797A patent/YU18797A/sr unknown
- 1997-05-12 CA CA002253869A patent/CA2253869C/en not_active Expired - Fee Related
- 1997-05-12 SV SV1997000034A patent/SV1997000034A/es not_active Application Discontinuation
- 1997-05-12 WO PCT/US1997/007975 patent/WO1997043238A1/en not_active Application Discontinuation
- 1997-05-12 EP EP97926454A patent/EP0912487A1/en not_active Withdrawn
- 1997-05-12 PE PE1997000362A patent/PE65998A1/es not_active Application Discontinuation
- 1997-05-14 ID IDP971607A patent/ID20291A/id unknown
Also Published As
Publication number | Publication date |
---|---|
CA2253869C (en) | 2003-04-22 |
ID20291A (id) | 1998-11-19 |
TW467892B (en) | 2001-12-11 |
TNSN97085A1 (fr) | 2005-03-15 |
YU18797A (en) | 1999-11-22 |
PA8429401A1 (es) | 2000-05-24 |
HRP970246B1 (en) | 2002-04-30 |
WO1997043238A1 (en) | 1997-11-20 |
JP3417951B2 (ja) | 2003-06-16 |
CN1225622A (zh) | 1999-08-11 |
ZA974032B (en) | 1998-02-19 |
PE65998A1 (es) | 1998-10-20 |
JPH11509870A (ja) | 1999-08-31 |
CO4990925A1 (es) | 2000-12-26 |
AR007096A1 (es) | 1999-10-13 |
CN1163466C (zh) | 2004-08-25 |
EP0912487A1 (en) | 1999-05-06 |
AU727648B2 (en) | 2000-12-21 |
SV1997000034A (es) | 1999-07-05 |
CA2253869A1 (en) | 1997-11-20 |
HRP970246A2 (en) | 1998-04-30 |
AU3121997A (en) | 1997-12-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MY105328A (en) | Blocking agents of edrf effect or formation for the treatment of shock. | |
DE69512797D1 (en) | Prostaglandin-synthase hemmer | |
HUT76548A (en) | Aryl-sulfonamido-hydroxamic acids of matrix-metalloproteinase-inhibiting activity | |
BR9713417A (pt) | Composto de açúcar, agente gelificante, composição de agente gelificante, processos para suas preparações e composição de gel. | |
CA2264254A1 (en) | Phosphinic acid amides as matrix metalloprotease inhibitors | |
EA200100139A1 (ru) | Фармацевтические композиции, содержащие 2-хинолоны | |
ATE15749T1 (de) | Synergistische konservierungszusammensetzungen, diese enthaltende produkte und verfahren zu ihren gebrauch. | |
BR8901097A (pt) | Processo para a preparacao de uma composicao biocida | |
KR940703655A (ko) | 약제학적 조성물과 그 제조방법 | |
EP0331382A3 (en) | Transdermal flux enhancing compositions | |
MY132470A (en) | Substituted oxobutyric acids as matrix metalloprotease inhibitors | |
NO994659L (no) | Nye pyridinderivater og farmasöytiske preparater inneholdende slike | |
KR890016017A (ko) | 치환된 1-(1h-이미다졸-4-일)알킬-벤즈아미드 | |
KR950703941A (ko) | 일산화질소 합성 억제제(nitrogen monoxide synthesis inhibitor) | |
ATE239711T1 (de) | Neue allythiopyridazinderivate und verfahren zu ihrer herstellung | |
ATE228303T1 (de) | Synergistische antimikrobielle zusammensetzungen die 1-hydroxymethylpyrazol und präservierungsmittel enthalten | |
KR960706476A (ko) | 인터류킨-1 활성 억제제로서의 신규한 벤젠설포닐아민 유도체(Novel benzen-esulfonylimine derivatives as inhibitors of lL-1 action) | |
KR870010782A (ko) | 아인산 유도체를 함유하는 살균 조성물 | |
EA200400523A1 (ru) | Производные [[2-(амино-3,4-диоксо-1-циклобутен-1-ил)амино]алкил] кислоты, применяемые для лечения боли | |
DE59002760D1 (de) | K2p pro-stabilisierung. | |
DE69515881D1 (de) | Pestizide zusammensetzungen, die ethoxylierte fettamine zur steigerung der effektivität von endothall und dessen salzen enthalten. | |
EA200000681A1 (ru) | Фунгицидная смесь на базе амидных соединений и производных пиридина | |
GB1449768A (en) | Liquid herbicidal compositions and process for the destruction of troublesome and harmful weeds | |
ES8503199A1 (es) | Procedimiento para la preparacion de nuevos agentes antihelminticos derivados de imidiazoles. | |
IE39679L (en) | Methods and compositions for killing parasites of warm¹blooded animals |