MY109679A - Anti-androgenic cyclo and bicyclo alkenes - Google Patents
Anti-androgenic cyclo and bicyclo alkenesInfo
- Publication number
- MY109679A MY109679A MYPI93002449A MYPI19932449A MY109679A MY 109679 A MY109679 A MY 109679A MY PI93002449 A MYPI93002449 A MY PI93002449A MY PI19932449 A MYPI19932449 A MY PI19932449A MY 109679 A MY109679 A MY 109679A
- Authority
- MY
- Malaysia
- Prior art keywords
- compounds
- androgen
- formula
- carbons
- metabolism
- Prior art date
Links
- 230000002280 anti-androgenic effect Effects 0.000 title abstract 3
- 150000001336 alkenes Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 102000001307 androgen receptors Human genes 0.000 abstract 2
- 108010080146 androgen receptors Proteins 0.000 abstract 2
- 239000000051 antiandrogen Substances 0.000 abstract 2
- 210000000481 breast Anatomy 0.000 abstract 2
- 230000004060 metabolic process Effects 0.000 abstract 2
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 201000004384 Alopecia Diseases 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000002260 Keloid Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 206010068168 androgenetic alopecia Diseases 0.000 abstract 1
- 230000003416 augmentation Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 201000008482 osteoarthritis Diseases 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/10—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by etherified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/128—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by alcoholysis
- C07C29/1285—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by alcoholysis of esters of organic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/723—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
- C07C49/727—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
- C07C49/733—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system having two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fats And Perfumes (AREA)
- Pyrane Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Polymerisation Methods In General (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Saccharide Compounds (AREA)
- Liquid Crystal Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08004972 US5264619B1 (en) | 1993-01-15 | 1993-01-15 | Anti-androgenic cyclo and bicyclo alkenes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY109679A true MY109679A (en) | 1997-04-30 |
Family
ID=21713473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI93002449A MY109679A (en) | 1993-01-15 | 1993-11-22 | Anti-androgenic cyclo and bicyclo alkenes |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5264619B1 (OSRAM) |
| EP (1) | EP0679152B1 (OSRAM) |
| JP (1) | JPH08505851A (OSRAM) |
| KR (1) | KR960700213A (OSRAM) |
| CN (1) | CN1051758C (OSRAM) |
| AT (1) | ATE157342T1 (OSRAM) |
| AU (1) | AU672265B2 (OSRAM) |
| BR (1) | BR9307758A (OSRAM) |
| CA (1) | CA2152588C (OSRAM) |
| DE (1) | DE69313466T2 (OSRAM) |
| DK (1) | DK0679152T3 (OSRAM) |
| ES (1) | ES2107793T3 (OSRAM) |
| GR (1) | GR3025092T3 (OSRAM) |
| IL (1) | IL107699A0 (OSRAM) |
| MX (1) | MX9307235A (OSRAM) |
| MY (1) | MY109679A (OSRAM) |
| NO (1) | NO952787L (OSRAM) |
| PH (1) | PH30285A (OSRAM) |
| TW (1) | TW294656B (OSRAM) |
| WO (1) | WO1994015900A1 (OSRAM) |
| ZA (1) | ZA938767B (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4311870C2 (de) * | 1993-04-10 | 1998-07-30 | Altramed Holdings Ltd | Verwendung eines Anti-Östrigens zur Therapie und Prophylaxe von Demenz-Erkrankungen |
| DE4320896A1 (de) * | 1993-06-24 | 1995-01-05 | Denecke Rainer Dr Med Vet | Präparat zur Therapie und Prophylaxe von Demenz-Erkrankungen |
| WO1997002041A1 (en) | 1995-07-03 | 1997-01-23 | Crandall Wilson T | Transdermal and oral treatment of androgenic alopecia |
| US6331537B1 (en) | 1998-06-03 | 2001-12-18 | Gpi Nil Holdings, Inc. | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds |
| KR20010052503A (ko) | 1998-06-03 | 2001-06-25 | 다니엘 피. 맥컬럼 | Ｎ-헤테로사이클릭 카복실산 또는 카복실산 등입체의ｎ-결합된 설폰아미드 |
| WO1999062879A1 (en) * | 1998-06-03 | 1999-12-09 | Gpi Nil Holdings, Inc. | Ureas and carbamates of n-heterocyclic carboxylic acids and carboxylic acid isosteres |
| US7253169B2 (en) | 1999-11-12 | 2007-08-07 | Gliamed, Inc. | Aza compounds, pharmaceutical compositions and methods of use |
| US6417189B1 (en) | 1999-11-12 | 2002-07-09 | Gpi Nil Holdings, Inc. | AZA compounds, pharmaceutical compositions and methods of use |
| MXPA02006134A (es) | 1999-12-21 | 2002-12-13 | Guilford Pharm Inc | Compuestos derivados de hidantoina, composiciones farmaceuticas y metodos de uso de los mismos. |
| US6768026B2 (en) * | 2002-01-09 | 2004-07-27 | John P. Mamana | Compounds for blocking androgen receptors |
| US20070048246A1 (en) * | 2005-09-01 | 2007-03-01 | Biophysica Research, Inc. | Novel skin care compositions |
| US20110021869A1 (en) * | 2009-07-24 | 2011-01-27 | Hilary John Cholhan | Single-incision minimally-invasive surgical repair of pelvic organ/vaginal prolapse conditions |
| US8410314B1 (en) | 2010-06-21 | 2013-04-02 | Bcs Business Consulting Services Pte Ltd. | Method of synthesis |
| WO2014140655A1 (en) | 2013-03-11 | 2014-09-18 | Bcs Business Consulting Services Pte Ltd. | Method of synthesis |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7408062A (OSRAM) * | 1973-06-20 | 1974-12-24 | ||
| US4689345A (en) * | 1982-05-06 | 1987-08-25 | Cbd Corporation | Oxygenated alkyl substituted bicyclo alkanes |
| US4535182A (en) * | 1982-08-26 | 1985-08-13 | Sumitomo Chemical Company, Limited | Process for preparing 2-cyclopentenone esters |
| GB8406000D0 (en) * | 1984-03-07 | 1984-04-11 | Ici Plc | Olefine derivatives |
| JPH0637388B2 (ja) * | 1986-02-17 | 1994-05-18 | 千寿製薬株式会社 | 水性液剤 |
| US4963583A (en) * | 1987-10-05 | 1990-10-16 | Ciba-Geigy Corporation | Beta-ionone derivatives as antifungal agents |
| JP2608089B2 (ja) * | 1988-03-09 | 1997-05-07 | 帝人株式会社 | ４−ヒドロキシ−２−シクロペンテノン類およびそれを含有する薬剤組成物 |
| US5010105A (en) * | 1989-06-09 | 1991-04-23 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
-
1993
- 1993-01-15 US US08004972 patent/US5264619B1/en not_active Expired - Fee Related
- 1993-10-14 DE DE69313466T patent/DE69313466T2/de not_active Expired - Fee Related
- 1993-10-14 ES ES94901162T patent/ES2107793T3/es not_active Expired - Lifetime
- 1993-10-14 DK DK94901162.1T patent/DK0679152T3/da active
- 1993-10-14 EP EP94901162A patent/EP0679152B1/en not_active Expired - Lifetime
- 1993-10-14 CA CA002152588A patent/CA2152588C/en not_active Expired - Fee Related
- 1993-10-14 WO PCT/US1993/009844 patent/WO1994015900A1/en not_active Ceased
- 1993-10-14 AT AT94901162T patent/ATE157342T1/de not_active IP Right Cessation
- 1993-10-14 KR KR1019950702903A patent/KR960700213A/ko not_active Withdrawn
- 1993-10-14 BR BR9307758A patent/BR9307758A/pt not_active Application Discontinuation
- 1993-10-14 AU AU55847/94A patent/AU672265B2/en not_active Ceased
- 1993-10-14 JP JP6515960A patent/JPH08505851A/ja not_active Ceased
- 1993-11-19 MX MX9307235A patent/MX9307235A/es unknown
- 1993-11-22 IL IL10769993A patent/IL107699A0/xx unknown
- 1993-11-22 MY MYPI93002449A patent/MY109679A/en unknown
- 1993-11-22 PH PH47301A patent/PH30285A/en unknown
- 1993-11-22 CN CN93114713A patent/CN1051758C/zh not_active Expired - Fee Related
- 1993-11-23 ZA ZA938767A patent/ZA938767B/xx unknown
- 1993-11-23 TW TW082109864A patent/TW294656B/zh active
-
1995
- 1995-07-13 NO NO952787A patent/NO952787L/no unknown
-
1997
- 1997-10-20 GR GR970402733T patent/GR3025092T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5264619A (en) | 1993-11-23 |
| TW294656B (OSRAM) | 1997-01-01 |
| DE69313466D1 (en) | 1997-10-02 |
| CN1051758C (zh) | 2000-04-26 |
| JPH08505851A (ja) | 1996-06-25 |
| DE69313466T2 (de) | 1998-04-02 |
| CA2152588C (en) | 1998-05-05 |
| CA2152588A1 (en) | 1994-07-21 |
| PH30285A (en) | 1997-02-20 |
| BR9307758A (pt) | 1995-10-24 |
| WO1994015900A1 (en) | 1994-07-21 |
| ATE157342T1 (de) | 1997-09-15 |
| EP0679152A1 (en) | 1995-11-02 |
| ES2107793T3 (es) | 1997-12-01 |
| AU672265B2 (en) | 1996-09-26 |
| DK0679152T3 (da) | 1998-02-23 |
| IL107699A0 (en) | 1994-02-27 |
| MX9307235A (es) | 1994-07-29 |
| AU5584794A (en) | 1994-08-15 |
| KR960700213A (ko) | 1996-01-19 |
| GR3025092T3 (en) | 1998-01-30 |
| EP0679152B1 (en) | 1997-08-27 |
| ZA938767B (en) | 1994-06-30 |
| NO952787D0 (no) | 1995-07-13 |
| CN1091733A (zh) | 1994-09-07 |
| US5264619B1 (en) | 1996-05-14 |
| NO952787L (no) | 1995-09-01 |
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