MXPA98010220A - Complex preparations characterized by beta content - Google Patents

Abstract

Preparations, specifically for local use, containing compounds containing ions, astringents, binders and adhesives, possibly lipotropic compounds, antifungal, anti-inflammatory and plant components, characterized by a beta-containing content

Description

COMPLEX PREPARATIONS CHARACTERIZED BY BETAINE CONTENT DESCRIPTIVE MEMORY -r The invention relates to complex preparations for local, intracorporeal or oral treatment that affects, maintains and improves cellular function, cellular metabolism, physiological processes, microcirculation, immunity, biostasis and / or prevention, healing, care of various manifestations of tissue damage, tissue change and deformation caused by exogenous and / or endogenic factors, or arising due to them, in humans and animals. It is known that there are already agents and preparations for treating and / or improving cell function, physiological processes or immunity. It is also known that there are local agents for the stimulation of the surface of the blood circulation and for the healing and care of the human and animal body. The bases of these agents, especially when dermal agents are involved, are usually antibiotics, cortisones, antifungals and other often very dangerous materials. Due to side effects, these are contraindicated, for example during pregnancy or for infants. These agents are also associated with other disadvantages because, if they are effective in any way, they are therapeutically effective only after prolonged use or when used in connection with other agents, or with a special diet. None of these known agents contain ionic preparations, which can introduce, at high osmotic pressure, the physiologically necessary materials, such as substances containing amino acids, enzymes, • * mineral substances, vitamins, etc., inside cells and blood plasma due to its effect on the cell membrane. It is an object of this invention to provide preparations with natural materials on a phytobiological basis, especially for local use for rapid, effective treatment that affects and maintains cellular function, cellular metabolism, physiological processes, microarticulation, immunity, resistance , homeotasis and / or prevention, cure, care of various manifestations of tissue damage, changes and tissue deformation, caused by exogenous and / or endogenic influences or arising due to these, in humans and animals, which, at high osmotic pressure, carry the ions and the active ingredients to the cellular layer, selectively make the membrane porous and enter inside the cells and the blood plasma and, with the necessary substances, mineral materials, amino acids, enzymes, vitamins, proteins, acid and / or other components, provide and contribute significantly to reinforce and boost the processes physiological to establish the balance in the organism.

This object is achieved in accordance with the principles of the invention. It is known in the prior art (DE patent 3816442 C2) a local agent for the treatment of tissue and microbial tissue damage. In addition, the United Kingdom patent application no.2 106 386 relates to a preparation for the treatment of the scalp and hair containing a mixture of metals (especially iron salts, magnesium salts, manganese salts, calcium salts, zinc salts and copper salts), phosphates , carbohydrates, amino acids, vitamins and oils. The invention is based on special compositions of the preparations. The preparations according to the invention comprise compounds containing ions, salts, astringent components, amphoteric surfactants, wetting agents, binding agents and adhesives, essential oils, to which one or more materials may be added, if necessary. appropriate, such as enzymes, vitamins, proteins and auxiliary components. The preparations according to the invention are characterized not only by the presence of compounds containing ions, but also by the presence of lipotropic active agents, preferably betaine. Compounds containing ions and salts with Na, K, Mg, Ca and phosphate are preferred; the preferred astringents are tannin, aspartic acid and / or sandalwood oil; a preferred wetting agent is glycerin and a preferred ether oil is peppermint oil. Preferred binding agents preferably include pectin and / or a hydrogel such as agar gel. The preparations according to the invention have a comparatively low or physiologically normal pH value and a comparatively high osmotic pressure. The combined components according to the invention have a surprisingly effective synergistic effect whereby cell function, metabolism, physiological processes and microcirculation are promoted, while simultaneously supplying and supplying to all tissues important substances, such as as mineral substances, amino acids, dextrose, enzymes, vitamins and proteins, which is especially advantageous in the case of physical exertion and altered physiological balance. If necessary, the preparations according to the invention may contain, among other ingredients, vegetable extracts, emulsifiers, amino acids, lanolin, glycine, choline, eucerin, dyes, waxes, bacteriostatic agents, oils, starches, tin, iron, fats, gelatins, preservatives, petrolatum, camphor, carbamide, surfactants, paraffins. The amount of the components is variable and can be 0.01% for one component and 20% more for another. The examples that are provided explain this more widely.

In its consistency or administration, the preparations according to the invention can be an infusible and / or local solution, ointment, cream, gel, lotion, powder, sprayer, foam, emulsion, tablets, capsules, textile wound dressings or can be mixed partially or completely with other agents or other materials. In the preparations according to the invention, the amounts provided can be increased or decreased and / or the components can be omitted and / or exchanged. The preparations according to the invention vary in their decomposition and the principle and effect resulting from their function, period of effect, methods of use, interaction and availability as do other comparable agents of the prior art, especially agents that are for local use. to affect, boost, maintain and / or restore cellular function, physiological processes, microcirculation, immunity in human or animal tissue. As a lipotropic active ingredient, betaine is known as a component in the production of sedatives, surfactants, body cleansers to inhibit infections. But it should be considered as very surprising that the betaine reaches the deep cell level with the lipotropic substance containing amino acids in preparations containing ions according to the invention via high-pressure osmotic ions and produces an exchange of cells and nutrients intensely high, and an improved microcirculation and extensive physiological processes. It should be considered as very surprising that, only in the preparations indicated according to the invention, betaine effectively reaches the deep tissue and manifests an effective influence of cellular and physiological processes. It should be considered as surprising that effective substances, such as betaine, but also enzymes, vitamins and other essential materials and elements, can be rapidly and precisely administered locally via the preparations containing ions according to the invention. and avoid osmotic pressure. The ionic results confirm these surprising effects and show a significantly improved microcirculation and improved and increased physiological processes, which are manifested especially in the tissues of the skin and muscles, fibers, joints and healing processes. These surprising results can also offer new advantages and opportunities in the immunological, hematological and metabolic fields. The surprising effect of the betaine-containing compounds according to the invention was confirmed by the following clinical tests: 15 individuals, female, aged 20-58, were divided into three groups of five each (A, B and C). All individuals exhibited a characteristic manifestation of cellulitis in the second stage or third in the thigh: test with positive forceps, mattress-shaped protuberances visible to the naked eye when standing (according to the stage) or when they were lying down as well as when they were standing (third stage), loose skin tone. These symptoms are the result of interrupted, deficient cellular function and microcirculation, which results in the accumulation of water and fat in the tissue. During the trial period it was required that the individuals did not change anything about their lifestyle and that they did not start any diet or aerobic / sports activities. Group A applied the ion-containing preparation according to the invention to the affected skin area (right thigh) once a day for 14 days, applying it in a thin layer and massaging it into the skin until it was completely absorbed. . The circumference of the thigh was measured in a place marked on the first day and the last day of the treatment. The stretching and smoothing of the skin was visible already after four days. After eight days of. treatment, you could observe a clearly visible reduction of the pertuberance on the surface of the skin. After 14 days, the surface of the treated skin was smooth, flexible, elastic and stretched. A reduction in thigh circumference of up to 3 cm was measured in all five individuals. Group B underwent the same treatment with a preparation that contained ions such as group A, but without the inclusion of betaine. After about ten days, light smoothing and stretching of the skin was confirmed in four of the five individuals. However, after the fourteen day treatment, there were no more changes or improvements in the manifestation of cellulite. Group C underwent the same treatment of a body cleansing agent that contained betaine. After fourteen days, none of the individuals showed an improvement or a positive change, either in the condition of the skin or in the circumference of the thigh.

EXAMPLE 1 EXAMPLE 2 EXAMPLE 3 EXAMPLE 4 EXAMPLE 5 EXAMPLE 6

Claims (4)

NOVELTY OF THE INVENTION CLAIMS

1. - Complex preparations containing the following components: a) one or more compounds containing ions and lipotropic substances, b) an astringent agent, a binding agent and adhesive, a wetting agent and one or more essential oils, c) if necessary amino acids , proteins, antifungal agents, anti-inflammatory agents, plants and other components necessary for the purpose of the invention, characterized by a betaine content.

2. - Preparations according to claim 1, further characterized in that component a) contains compounds of Na-, K-, Cl-, Mg-, Ca, and phosphate and at least one of these compounds.

3. Preparations according to claims 1 and 2, further characterized in that component b) contains tannin or an acidic compound such as astringent, pectin or a gel as binder and adhesive, peppermint oil as ether oil, or at least one of these components.

4. - Preparations according to claims 1, 2 and 3, further characterized in that component c) contains, if necessary, substances containing amino acids, substances that contain. acids, lipotropic substances, bacteriostatic agents, lanolin, eucerin, plant extracts, waxes, dyes, oils, starches, tin, iron, sulphate compounds, jellies, fats, carbamide, surfactants, paraffins, petroleum jelly, sandalwood oil, camphor, or conservatives.