MXPA98006838A - Compositions disinfect - Google Patents

Abstract

The present invention relates to disinfectant compositions comprising a peroxygen bleach, an amphoteric surfactant, glutaraldehyde and an antimicrobial or active essential oil thereof, and a method for disinfecting the surface

Description

DISINFECTANT COMPOSITIONS TECHNICAL FIELD The present invention relates to antimicrobial compositions that can be used to disinfect and clean various surfaces including animated surfaces (eg human skin, mouth and simples) and inanimate surfaces that include but are not limited to such hard surfaces. as walls »tiles» table tops »glass» bathroom surfaces »kitchen surfaces and dishes» as well as fabrics »clothes» rugs and the like.

BACKGROUND The antimicrobial / antibacterial compositions include materials that have the ability to disinfect. It is generally recognized that a disinfectant material greatly reduces or even eliminates microorganisms, for example »bacteria» that exist on a surface. Compositions based on halogen-containing compounds such as hipee! orito "or based on quaternary compounds" have been described extensively in the art for purposes of desfection. The compositions comprising peroxide bleach are also known as disinfectant compositions. However, compositions based on, for example, peroxide bleach as the only anionic compound (typically at a level of 1% by weight of the total composition) are not completely effective, especially when used at high levels. Dilution levels »eg at a dilution level of 1:50 (composition) to disinfect soiled surfaces» eg »surfaces that need to be both washed and disinfected. In fact, the presence of organic / inorganic soils decreases the bactericidal activity of many aniicribians such as peroxygen bleach, thus resulting in a lower bactericidal activity / disinfecting potency for the compositions comprising them. Thus, it is an object of the present invention to provide compositions that provide excellent disinfection on soiled surfaces specifically for heavily soiled surfaces even when used under highly diluted conditions. It has now been discovered that this can be achieved by combining different antimicrobial compounds together, ie by combining a peroxygen bleach an amphoteric surfactant or a mixture thereof, glutaraldehyde and an antimicrobial essential oil or an active thereof or mixtures thereof. thereof. It has particularly been found that a composition comprising said peroxygen bleach said amphoteric surfactant said glutaraldehyde and said antimicrobial essential oil or an active thereof, provides excellent disinfection on soiled surfaces including heavily soiled surfaces, including highly diluted conditions "ie" up to a level of dilution of said composition to water of 1: 100. An advantage of the present invention is that excellent disinfection is provided under dirty conditions over a wide range of bacterial strains including Gram-positive and Gram-negative bacterial strains but also more resistant microorganisms such as fungi. Another advantage of the compositions of the present invention is that apart from the disinfection properties supplied, an adequate cleaning performance is also provided. Similarly, the compositions according to the present invention are suitable for use on all types of surfaces including animated surfaces (eg "human skin and / or mouth" when used as an oral preparation or toothpaste) as well as inanimate surfaces. In fact, this technology is particularly suitable in hard surface applications as well as in laundry applications »eg, as a laundry detergent or laundry additive in a so-called" soaking mode "," washing mode ". or even as a laundry pre-cleaner in a "pre-treatment mode". Very particularly, the compositions according to the present i They are suitable for use safely on delicate surfaces including those surfaces in contact with food and / or babies. In fact, when the compositions according to the present invention are used under diluted conditions, the amount of chemical residues left on a surface disinfected with them is reduced. In this way, it may not be necessary to rinse a hard surface, for example, after the compositions of the present invention have been applied thereto under diluted conditions. A further advantage of the compositions of the present invention is that they can be provided in different forms »eg in liquid form packed in a conventional detergent bottle» or in a sprayable or foam form packed in a spray dispenser. foam "or in the form of towels incorporating said composition" or in a non-liquid form. EP-B-288 SB9 discloses a hard surface liquid comprising effective antimicrobial amounts of pine oil and at least one soluble organic oil. No other antimicrobial compounds are mentioned, much less a peroxygen bleach. EP-241390 discloses that textiles contaminated with bacteria can be disinfected by first treating with a detergent and then with a peroxide bleaching agent in an aqueous bath at pH 9-13 in the presence of noncompressed calcium. Other antimicrobial compounds are not described. The document EU-, 404 »191 discloses that the compounds such as onopersulfate have bactericidal, fungicidal and virucidal properties. Document EU-4 '404,191 discloses that compositions comprising monopersulfate can be used in diluted form to treat hard surfaces. However, other anti-crobian compounds are not mentioned. EP-A-667 392 discloses hard surface cleaning compositions comprising hydrogen peroxide and a surfactant / thickener component comprising alkylether sulfate surfactant together with an amine or betaine oxide. The compositions of that document have a pH of from 7 to 10. No other antimicrobial compounds are described and fewer essential oils or active ingredients thereof or gl taraldehyde. The document EU-5 »403» 587 discloses aqueous antimicrobial compositions which can be used to sanitize, disinfect and clean hard surfaces. Most particularly, document EU-5,403,587 discloses aqueous compositions (pH 1 to 12) comprising essential oils (0.02% to 5%), which exhibit efficacy in antimicrobial properties, such as thyme oil, eucalyptus oil, oil Nail and the like "and a sufficient solubilizing or dispersing agent to form an aqueous solution or dispersion of said essential oils in a water vehicle. Said compositions may further comprise other antimicrobial ingredients such as phenolic compounds and quaternary ammonium compounds.; however, amphoteric surfactants or peroxygen bleaches are not disclosed. EU-5, 368,749 discloses compositions for inhibiting the growth of aerobic microorganisms including bacteria and fungi, said compositions include an oxidant and glutaraldehyde. The oxidants can be selected from the group of chlorine, bromine, monopersulfate, perborate, hydrogen peroxide, peracetic acid and percarbonate. It is mentioned that the oxidant exhibits a synergistic effect when added to glutaraldehyde. Other antimicrobial compounds such as essential and active oils thereof or amphoteric surfactants are not described. EU-3 »852» 210 discloses aqueous oxygen releasing compositions suitable for a wide range of industrial and domestic applications, for example, as laundry bleach detergents or as hard surface cleaners. The germicidal and bactericidal activity of said compositions makes them also suitable for medical application. Said compositions (pH 2 to 10) comprise an active oxygen producing compound »eg, hydrogen peroxide (0.1-50%), a betaine or sulfobetaine (0.5-50%) such as cetylbetaine or lauryl sulfobetaine and agents non-ionic copolymer surfactants of polyethylene-polyoxypropylene block copolymers having a solubility in water of at least one gram per 100 ml of water and a molecular weight within the range of 1,000 to 15,000. No other antimicrobial compounds are described "and fewer essential oils or active ingredients thereof" or glutaraldehyde. J-6003B497 discloses a two-component foam-generating detergent composition comprising (a) an aqueous solution of hydrogen peroxide (0.5% -50%) »(b) an alkaline compound containing an alkaline substance having 0.1% at 50% alkalinity expressed in terms of NaOH »such as NaOH, KOH, Na2CO3. One of the two components (a) and (b) of said surfactant compositions comprises a surfactant, eg, amphoteric surfactants and / or at least one compound selected from terpene alcohols, cyclic terpene alcohols. and its esters such as geranium !. The compositions of document J-60038497 are designed to clean soils on hard materials such as plastics, joints and voids and corners particularly difficult to clean. Glutaraldehyde is not described. There is also no reference to disinfection.

BRIEF DESC IPCIOM OF THE INVENTION The present invention encompasses a de-inerting composition comprising a peroxygen bleach, an amphoteric surfactant, glutaraldehyde and an antimicrobial essential oil or an active ingredient thereof.

The present invention also encompasses a method for disinfecting a surface, wherein a composition comprising a peroxygen bleach, an amphoteric surfactant, glutaraldehyde and an antimicrobial essential oil or an active thereof is applied on said surface.

DETAILED DESCRIPTION OF THE INVENTION The disinfectant compositions according to the present invention comprise a peroxygen bleach, a ageinte amphoteric surfactant, glutaraldehyde and an antimicrobial essential oil or an active thereof. The compositions according to the present invention can be formulated as either liquid or non-liquid (e.g., "gel or paste form" or solid form such as powder or granulate). In case the compositions are formulated as solids, they will be mixed with a suitable solvent, typically water, before being used. In liquid form, the compositions are formulated prifferently, but not necessarily as aqueous compositions. Liquid compositions are preferred here for reasons of convenience of use. Co or an essential element, the compositions according to the present invention comprise a peroxygen bleach or mixtures thereof. The peroxygen blancher that is pre-fused is hydrogen peroxide, or a water-soluble source thereof, or mixtures thereof. It is more preferred to use hydrogen peroxide in the compositions according to the present invention. It is believed that the presence of said peroxygen bleach, especially hydrogen peroxide, persulfate and sims, in the compositions of the present invention contributes to the disinfecting properties of said compositions. In fact, said peroxygen bleach can attack the vital function of the microorganism's cells, "for example," it can inhibit the assembly of ribosome units within the cytoplasm of the microorganism's cells. Similarly, said peroxygen bleach, such as hydrogen peroxide, is a strong oxidant that generates hydroxyl free radicals that attack proteins and nucleic acids. Moreover, the presence of said peroxygen bleach, especially hydrogen peroxide, provides strong stain removal benefits that are particularly noticeable for example in laundry and hard surface cleaning applications. As used herein, a source of hydrogen peroxide refers to any compound that produces hydrogen peroxide when said compound is in contact with water. Suitable water soluble sources of hydrogen peroxide to be used herein include percarbonates, persilicates, persulfates such as monopersulfate, perborates and peroxyacids such as diperoxydodecanoic acid (DPDA), magnesium peristaltic acid and mixtures thereof.

Further »other kinds of peroxides can be used as an alternative for hydrogen peroxide and hydrogen peroxide sources» or in combination with hydrogen peroxide and sources thereof. Suitable classes include dialkeroperoxy, diisocyl peroxides, preformed percarboxylic acids, peroxides and / or organic and inorganic hydroperoxides. Typically, the compositions herein comprise at least 0.01% by weight of the total composition of said peroxygen bleach or mixtures thereof, preferably from 0.1% to 15%, and most preferably from 1% to 10%. As a second essential ingredient, the compositions according to the present invention comprise an amphoteric surfactant or mixtures thereof. It is speculated that said amphoteric surfactants have a double action. In fact, they help disinfection by increasing the permeability of the bacterial cell wall, thus allowing other active ingredients to enter the cell. Likewise, said surfactants contribute to the cleaning performance of the compositions herein. Moreover »due to the smooth action profile of said amphoteric surfactants, especially betaine or sulphaetaine surfactants, the compositions herein may be particularly suitable for the cleaning of delicate surfaces »ie, delicate laundry or surfaces in contact with foods and / or babies, especially when used under diluted. For example, betaine and / or sulfobetaine surfactants are also extremely gentle on the skin, and thus contribute to the convenience of using the compositions of the present invention. The amphoteric surfactants that are preferred include betaine and sulfobetaine surfactants, derivatives thereof, and mixtures thereof. The betaine and sulfobetaine surfactants suitable for use in the compositions of the present invention are the betaine / sulfobetaine and betaine type detergents in which the molecule contains both basic and acid groups which form an internal salt which gives the molecule groups cationic and anionic hydrophilic over a wide range of pH values. Some common examples of these detergents are described in the patents of E.U.A. Nos. 2 »082» 275 »2» 702,279 and 2,255,082 »incorporated herein by reference. Preferred betaine and sulfobetaine surfactants are in accordance with the formula: wherein R 1 is an alkyl radical containing from 1 to 24 carbon atoms, preferably from 8 to 18 and very preferably from 12 to 14, wherein R 2 and R 3 contain from 1 to 3 carbon atoms and preferably 1 atom of carbon "wherein n is an integer of 1 to 1" preferably from 1 to 6 and most preferably is 1, and is selected from the group consisting of carboxyl and sulfonyl radicals "and wherein the sum of the radicals R1" R2 and R3 is from about 14 to about 24 carbon atoms "or mixtures thereof. Examples of particularly suitable betaine surfactants include alkyldimeti Ibetaine C12-Cia such as cocobetaine and Idi eti Ibetaine of C10-C16 such co or lauryl 1-etaine. Cocobetaine is commercially available from Seppic under the trade name of Amoni 1 265R »and lauryl betaine is commercially available from Albright & Wilson under the trade name Empi gene BB / LR. Other amphoteric surfactants suitable for use herein include the amine oxides or mixtures thereof. Amine oxides are preferred herein because they contribute to the disinfecting properties of the compositions herein. In fact, they help disinfect the membrane / wall of the bacterium cell, thus allowing other antimicrobial agents to enter the cell and attack, for example, the inner part of the cell. Amine oxides suitable for use herein have the following formula R ^ ^ R ^ NO, wherein each of R1, R2 and R3 is independently a straight or branched and saturated hydrocarbon chain containing from 1 to 30 carbon atoms. carbon. Amine oxides suitable for use in accordance with the present invention are amine oxides having the following formula R ^ ^ RaNO wherein R 1 is a hydrocarbon chain containing from 1 to 30 carbon atoms, preferably from S to 20. carbon atoms, very preferably from S to 14 and more preferably from 8 to 10, and wherein R 2 and R 3 are independently or unsubstituted linear or branched hydrocarbon chains containing from 1 to 4 carbon atoms, preferably from 1 to 4 carbon atoms; 3 carbon atoms and very preferably are methyl groups. R1 can be a straight or branched and saturated hydrocarbon chain. The amine oxides which are preferred to be used here are, for example, the amine oxides of C8-C10 naturally mixed, as well as the C12-C1S amine oxides commercially available from Hoechst. In a preferred embodiment of the present invention wherein the compositions herein are particularly suitable for the disinfection of a hard surface, the surfactant agent is typically a surfactant system comprising an amine oxide and a betaine surfactant. or sulfobetaine, preferably at a weight ratio of amine oxide to betaine or sulfobetaine of 2: 1 to 100: 1. The use of such a surfactant system in the compositions herein suitable for disinfecting a hard surface, provides an effective cleaning performance and provides brightening on the cleaned surfaces "ie, the amount of film / streaking left on the surface. cleaned surface that has been treated with said compositions is minimal. Typically, the compositions herein comprise at least 0.005% by weight of the total composition of said amphoteric surfactant, or mixtures thereof preferably from 0.01% to 10% and most preferably from 0.1% to 5%. As a third essential ingredient, the compositions according to the present invention comprise glwtaraldehyde. Glutaraldehyde is available commercially from Union Carbide or BASF. Typically, the compositions herein comprise at least 0.003% by weight of the total composition of said glutaraldehyde, preferably from 0.008% to 4% and very preferably from 0.2% to 2%. As a fourth essential ingredient, the compositions of according to the present invention comprise an antimicrobial essential oil or an active thereof or mixtures thereof. Suitable antimicrobial essential oils for use in the compositions herein are those essential oils that exhibit antimicrobial activity. By "active antimicrobial essential oil" is meant here any ingredient of essential oils that exhibits antimicrobial activity. It is speculated that said antimicrobial essential oils and actives thereof act as protein denaturing agents. Likewise, said antimicrobial essential oils and active ingredients thereof are naturally occurring compounds that contribute to the safety profile of the compositions of the present invention when they are used to disinfect any surface. An additional advantage of the presence of said antimicrobial actives of essential oils and active ingredients thereof is that they can impart a pleasing odor to the disinfectant compositions of the present invention without the need to add a perfume. In fact »the disinfectant compositions according to the present invention provide not only excellent disinfecting properties on the soiled surfaces that will be disinfected, but also a good aroma. These antimicrobial essential oils include »but are not limited to, those obtained from thyme» lemon grass (Cymbopogon citratus), citrus, lemons »oranges» anise, clove »anise seed» cinnamon »geranium» roses »mint» lavender »citronella »Eucalyptus» mint »camphor» sandalwood »cedar and mixtures thereof. The essential oil assets that will be used herein include but are not limited to, thymus! (present for example in thyme), eugenol (present for example in cinnamon), he said! (present for example in mint), geranium! (present for example in geranium or rose), verbenone (present for example in the vein pod), eucalyptol (present for example in eucalyptus), cec'rol (present for example in cedar), pinocarvone, carvacrol » anethole (present for example in the seed of anise) »hinoquitiol» berberine »terpineol, limonene, rotania and mixtures thereof. The essential oil assets that are preferred to use here are thymus, eugenol, verbenone, eucalyptol, limonene and / or geranium !. The scam! may be commercially available for example from Aldrich »and eugenol may be commercially available for example from Sigma or Bioindustries (SBI) or Manhei er Inc. Typically the compositions herein comprise at least 0.003% by weight of the total composition of said antimicrobial or active essential oil. same or mixtures thereof, preferably from 0.006% to 10% and most preferably from O.01% to 4%. It has now been discovered that improved disinfection is provided by the compositions of the present invention on soiled surfaces, including heavily soiled surfaces, even at high dilution levels, i.e., up to a level of dilution of said composition to water of: L: i? o By "heavily soiled surfaces" it is intended here to mean surfaces that are contaminated by organic and / or inorganic soils in an amount which is equivalent to a water solution of O.3 g / 1 of bovine albumins and hard water (cf. dirt conditions from 1 to European standard prEN 1276, CEN / TC 216 N59 of 11/95). By "improved de-fection" is meant here that the compositions of the present invention comprising said peroxygen bleach, said amphoteric surfactant, said "glutaraldehyde and said antimicrobial essential oil or active thereof" allow to reduce the amount of bacteria on a surface heavily soiled "in comparison with the same compositions without said peroxygen blancher" said amphoteric surfactant and said glutaraldehyde "or with the same compositions without said antimicrobial or active essential oil" especially when used in diluted form. In fact »excellent disinfection is obtained on several microorganisms that include Gram-positive bacteria such as Staphi lococcus aureus» and Gram-negative bacteria such as Pseudomonas aeroginosa. as well as on fungi such as Candi a albicans, present on heavily soiled surfaces. The disinfecting properties of a composition can be measured by the bactericidal activity of said composition. A suitable test method for evaluating the bactericidal activity of a composition is described in the European Standard prEN 1040, CEN / TC 216 N 78, November 1995, issued by the European committee for the norm »Brussels. European Standard prEN 1040 »CEN / TC 216 N 78 specifies a test method and requirements for the minimum bactericidal activity of a disinfectant composition. The test is passed if the bacterial colonies forming units (cfu) are reduced from 10"'' cfu (initial level) to 102 cfu (final level after contact with the disinfecting product), that is, a reduction of The viability of the compositions according to the present invention pass this test under heavily soiled conditions even if they are used under highly diluted conditions Another suitable test method for evaluating the bactericidal activity of the present compositions on heavily soiled surfaces is AFNOR T72-190R and T72- 301". The compositions according to the present invention can be applied to the surface to be disinfected in its concentrated form or in its diluted form, and preferably applied in its diluted form. By "dilute form" it is meant herein that the compositions according to the present invention which are in liquid form or in solid form can be diluted by the user with a liquid, typically water. Said compositions can be diluted by the user typically up to 100 times their weight of water, preferably 80 to 40 times their weight of water and most preferably SO to 30 times. Accordingly, the present invention also encompasses dilute disinfectant compositions obtainable by diluting a composition according to the present invention in water.

In the preferred embodiment of the present invention wherein said compositions are liquid and aqueous compositions, said aqueous compositions preferably have a pH of not more than 12, most preferably of 3.5 to 7, and more preferably of 4 to 5. The pH of the Compositions can be adjusted using organic acids such as citric acid, succinic acid, acetic acid, aspartic acid, lactic acid and the like, or inorganic acids, or alkalizing agents. The compositions of the present invention may further comprise any surfactant known to those skilled in the art, including nonionic, ammonium, cationic, and / or zwitterionic surfactants. Such surfactants are desirable, since they contribute to the cleaning performance of the compositions herein. Typically, the compositions according to the present invention comprise up to 50% by weight of the total composition of another surfactant »or mixtures thereof» above said surfactant or mixture thereof, preferably from 0.3% to 3% by weight. ?% and very preferably from 0.4% to 25%. The compositions of the present invention may also preferably comprise an anionic surfactant or mixtures thereof. Particularly suitable anionic surfactants which will be used herein include the water-soluble salts or acids of the formula R 0 S 0, wherein R is preferably a C 2 -C 2 hydrocarbyl, preferably alkyl or hydroxyalkyl having a alkyl component of Ca-Czo, most preferably an alkyl; or hi-hydroxyl of Ca-Ca <; 3 and M is H or a cation »v.gr .. an alkali metal cation (e.g., sodium, potassium, lithium), or ammonium or substituted ammonium (e.g.» methyl-, dimethyl cations and trimethylammonium and quaternary ammonium cations such as tetramethyl ammonium and dimethylpiperidinium cations and quaternary ammonium cations derived from alkylamines such as lamin, diethylamine, triethyl and mixtures thereof and the like). Other suitable anionic surfactants for use herein include the alkyl Idi in 1-ether sulfonates and alkylcarboxylates. Other ammonium surfactants may include salts (including, for example, sodium, potassium, ammonium and substituted ammonium salts such as mono-> di- and triethanolamine salts) of soap linear C ^ -Z-alkyl alkylbenzenesulfonates, primary or secondary alknesulfonates of Ce-C22 »olefin sulphonates of £ & - £, > sulphonated polycarboxylic acids prepared by the sulfonation of the pyro! raising alkaline earth metal citrates, e.g., as described in British Patent No. 1,082,179 »C 1 -C 6 alkyl ether-sulfates of Cm-Cz ^ (containing up to 10 moles of ethylene oxide); to the ethersulfonates such as methyl 4-Cl-4-methyl estersulfonates; ac Igl icerolsulfonates. olei 1-glycerol fatty sulfonates »ethylene oxide ethersulfates of alkylphenol, paraffinsulfonates, alkylsphosphates, isethionates such as acyl isethionates, N-acyl taurates, alkyl succinamates and sulphosuccinates, monoesters of sulfosuccinate (especially monoesters of C-S-C) : L &saturated and unsaturated) diesters of sulfosuccinate (especially saturated or unsaturated dC-esters), acyl sarcosinates, alkylpolysaccharide sulfates such as alkyl sulfates Ipol iglucoside (non-sulphonated non-ionic compounds si? Ndo described later). branched primary alkylsulphates »alkylpoly isotopes such as those of the formula RO (H20)? CHsCOO-M * wherein R is an alkyl of CT-C22» K is an integer from 0 to 10. and M it is a suitable salt-forming cation. Resin acids and hydrogenated resin acids are also suitable such as rosin, rosin, and resin acids and hydrogenated resin acids present in or derived from tallow oil. Additional examples are given in "Surface Active Agents and Detergents" (Vol. I and II by Schwartz »Perry and Berch). A variety of such surfactants are also generally described in the US patent. No. 3 »929» 67B »issued on December 30, 1975 to Laughlin» et al. column 23 »line 58 to column 29» line 23. The anionic surfactants which are preferred to be used in the compositions herein are C8-C1S alkyl sulphonates, C8-C16 alkyl sulphates, alkoxylated sulfates of CS-C16 ( e.g., alkyl ethoxylated sulfates of C8-C16) and mixtures thereof. Such anionic surfactants are preferred here because they have been found to contribute to the disinfecting properties of a composition herein. For example, C8-C1S aluyl sulfate acts by disrupting the membrane of the bacterial cell, thereby inhibiting "immature activities" by interrupting cell transport and / or by denaturing cellular proteins. Indeed, it is speculated that the improved disinfection performance is associated with the addition of an anionic surfactant, especially a C 8 -C 16 alkylsulphonate, an C 8 -C 16 alkylsulfate and / or an alkoxylated alkylsulfate of CS-C1G. example in a composition of the present invention will »multiply the mode of attack of said surfactant against Tas bacteria. Thus, another aspect of the present invention is the use of an anionic surfactant, especially a C8-C1S alkylsulfonate, a C8-C16 alkylsulfate and / or an alkylating agent. alkoxylated sulfate of CB-C1S in a composition of the present invention to improve the denaturing properties of said composition on gram negative and / or gram positive bacteria. The compositions of the present invention may preferably comprise a nonionic surfactant or mixtures thereof. Suitable nonionic surfactants for use herein are ethoxylated and / or propoxylated fatty alcohols which are commercially available with a variety of fatty alcohol chain lengths and a variety of degrees of ethoxylation. In fact, the HLB values of said alkoxylated nonionic surfactants depend essentially on the length of the fatty alcohol chain, the nature of the coxylation and the degree of alkoxylation. Surfactants catalogs listing a number of surfactants are available "including non-ionic surfactants, together with their respective HLB values. Particularly suitable for use herein as nonionic surfactants are the hydrophobic nonionic surfactants having a HLB (hydrophilic-lipophilic balance) below 1G, preferably below 15 and most preferably below 14. It has been found that non-ionic hydrophobic surfactants provide adequate fat-cutting properties. The hydrophobic nonionic surfactants that will be used in the compositions according to the present invention are the surfactants having an HLB below 16 and which are in accordance with the formula R0- (C3H ^ Q) "(C3H <; s0) mH > wherein R is an alkyl chain of Cs to C22 or an alkylbenzene chain of Cs to C2ß "and wherein n + m is from 0 to 20 and n is from 0 to 15 and m is from 0 to 20, preferably n + m is from 1 to 15 and »n and m are from 0.5 to 15» most preferably n + m is from 1 to 10 and »n and m are from 0 to 10. The R chains which are preferred to use here are the alkyl chains of Cs to C22. Accordingly, the suitable non-ionic hydrophobic surfactants to be used herein are Dobanol "91-2.5 (HLB = 8.l; R is a mixture of alkyl chains of Cß and Ci; L» n is 2.5 and m is O), or Lutensol "T03 (HLB = 8; R is an alkyl chain of C13, n is 3 and m is O), or Lutensol" A03 (HLB = 8; R is a mixture of Ci3 and CiS alkyl chains, n is 3 and m is O), or Tergitol "25L3 (HLB = 7.7, R is on the alkyl chain length scale of CA2 at ca.l5 'n is 3 and m is O)" or Dobanol "23-3 (HLB = 8.1» R is a mixture of alkyl chains of Ci; 2 and Ci3 »n is 3 and m is O)» or Dobanol "23-2 (HLB = 6.2; R is a mixture of Cx: alkyl chains and CA3, n is 2 and m is O), or Dobanol "45-7 (HLB = 11.S; R is a mixture of alkyl chains of Ci2 and CiS» n is 7 and m is O), oo Dobanol "23-6.5 (HLB = 11.9; R is a mixture of alkyl chains of Cass and C 3, n is 6.5 and is O), or Dobanol "25-7 (HLB = 12, R is a mixture of alkyl chains of CiS? and Cií5, n is 7 and m is O) , or Dobanol "91-5 (HLB = 11.6» R is a a mixture of alkyl chains of cs > And c 'n is 5 and is 0). or Dobanol "91-6 (HLB = 12.5.R is a mixture of alkyl chains of C« =, and C »n is 6 and m is O), or Dobanol" 91-8 (HLB = 13.7; R is a mixture of alkyl chains of CQ and cx 'p is 8 and m is 0)' or Dobanol "91-10 (HLB = 14.2» R is a mixture of alkyl chains of Cs and CA »n is 10 and m is 0)» or mixtures thereof Dobanol is preferred here "91-2.5. or Lutensol "T03, or Lutensol" A03, or Tergitol "25L3, or Dobanol" 23-3 or Dobanol "23-2 or mixtures thereof These Dobanol surfactants" are commercially available from SHELL. These Luternsol surfactants are commercially available from BASF and these Tergito surfactants are commercially available from UNION CARBIDE. Other suitable surfactants also include conventional C6-C20 soaps (alkali metal salts of a CS-C20 fatty acid, preferably sodium salts) The compositions herein may further comprise a chelating agent as an optional ingredient. Suitable chelating agents can be any of those known to those skilled in the art such as those selected from the group comprising phosphonate chelating agents, "aminophosphonate chelating agents," substituted heteroaromatic chelating agents, "amy nocarboxylate chelating agents," other chelating agents, and carboxylate »optionally substituted polyacrylating agents» biodegradable chelating agents such as ethylenediamine-N, l-α-di-succinic acid or mixtures thereof Phosphonate chelating agents suitable for use herein include etidronic acid »(acid 1) -hydroxieti len-diphosphonic (HEDP)) and / or alkali metal ethan-1-hydroxydiphos onatos. Amine phosphonate chelating agents suitable for use herein include aminoalkylamino (alkyphosphonates) »or tri-lotris (methyl 1 in), rifaphosphonates, ethanediamine or tetramethyl 1 in onathates and / or diethylmethiaminopentamethylphosphonates. The aminophosphonate chelating agents that are preferred to be used here are the diethyl-1-entriamipenta and the lympho-phosphonates. These phosphonate / amyphosphonate chelating agents can be present either in their acid form or as salts of different cations on some or all of their acid functionalities. Such phosphonate / aminophosphonate chelating agents are commercially available from Monsanto under the tradename DEQUEST. "Substituted heteroaromatic chelating agents to be used herein include hydroxypyridine N-oxide or a derivative thereof.The suitable hydroxypyrine N-oxides and derivatives thereof for use in accordance with the present invention are in accordance with the following formula: wherein X is nitrogen, Y is one of the following groups: oxygen, -CHO, -OH »- (CH2) -COOH, wherein n is an integer from 0 to 2.0, preferably from 0 to 10 and most preferably is O , and where Y is preferably oxygen. Accordingly, the N-oxides of particularly preferred hydroxypropionate and derivatives thereof for use herein is the 2-hydroxypyridine N-oxide. The hydroxypyridine N-oxides and derivatives thereof are commercially available from Sigma.

Aromatic-substituted aromatic chelating agents may also be useful in the compositions herein. See the patent of E.U.A. No. 3,812,044"issued May 21, 1974 to Connor et al. Compounds of this type which are preferred in acid form are dihydroxydisulfobenzenes such as l-2-dihydroxy-3,5-disulfobenzene. A biodegradable chelating agent which is preferred to be used herein is the eti-lendiamino-N'N-disuccinic acid or the alkali metal, alkaline earth, ammonium or substituted ammonium salts thereof, or mixtures thereof. The eti-lendiamino-N, Nt-disuccinic acids, especially the isomer (S, S) have been extensively described in the patent of E.U.A. 4 »704» 233, November 3, 1987 to Hartman and Perkins. The eti lendia ino-N'N'-disuccinic acid is commercially available, for example, under the tradename ssEDDS from Palmer Research Laboratories The lendiamino-N, N'-disuccinic acid is particularly suitable for use in the compositions herein SUMMARY Ami ocarboxylate chelating agents suitable and useful herein include ethylene tetraacetates, diethylenetriaminepentaacetates, diethyltriamine n-pentoacetate (DTPA), N-hydroxyethyi lendiaminotriacetates, or tri-otri acetates, ethyl endiami notetrapropi. onatos, tri et 1 entetraaminohexaacetatos, ethanol digl icinas, propi lendiaminotetraacetic acid (PDTA) and acid meti Igl icododiaceti co (MGDA), both in their acid form or in their forms of alkali metal salt »ammonium and substituted ammonium. used in the present are diethyltrinophenacetic acid (DTPA) »propylenedia inotetraacetic acid (PDTA) which is available commercially available from BASF under the tradename Tri 1 on FS "and methyglycinacetic acid (MGDA). Additional carboxylate chelating agents to be used herein include malonic acid »salicylic acid» glycine »aspartic acid» glutamic acid or mixtures thereof. Typically, the compositions according to the present invention comprise up to 5% by weight of the total composition of a chelating agent or mixtures thereof. same, preferably from 0.01% to 3% by weight and most preferably from 0.01% to 1.5%. The compositions herein may comprise a radical remover as a preferred optional ingredient. Suitable radical scavengers for use herein include the well-known mono- and substituted hydroxybenzenes and derivatives of Tos themselves, alkyl- and arcarboxylates and mixtures thereof. The radical scavengers that are preferred to be used here include di-tert-butyl hydroxy toluene (BHT), p-hydroxy toluene »hydroquinone (HQ), di-tert-butyl hydroquinone (DTBHQ), ono-tert-buty 1 hydroquinone (MTBHQ), ter-buti 1-hydroxy aniso! (BHA), p-hydroxy aniso !, benzoic acid, 2,5-dihydroxybenzoic acid, 2,5-dihydroxy terephthalic acid, toulic acid »catechol, t-util catechol, 4-al i 1-catechol, 4 -acetyl ecol »2-methoxy-phenol, 2-ethoxy-phenol, 2-metho-4- (2-propen 1) phenol, 3,4-dihydroxybenzaldehyde, 2,3-dihydroxybenzaldehyde» benzylamine, 1 » 1-3-tris (2- eti 1-4-hydroxy-5-t-butyl Ifenyl) butane »tet-butyl-hydroxyani-1a» p-hydroxyaniin-1 »as well as n-pro-1-alato. It is highly preferred here to use di-tert-butyl hydroxy toluene, which is available for example from SHELL under the tradename IONOL CP "and / or tert-butyl hydroxyanisole. to the stability of the peroxygen bleach-containing compositions herein. Typically, the compositions according to the present invention comprise up to 5% by weight of the total composition of a radical scavenger or mixtures thereof. same »preferably from 0.002% to 1.5% by weight and most preferably from 0.002% to 1%. The compositions herein may comprise as a preferred optional ingredient a solvent or mixtures of! same. When used, the solvents will advantageously provide an increased cleaning ability to the compositions herein. Suitable solvents for incorporation into the compositions according to the present invention include propylene glycol derivatives such as n-butoxypropanol or n-butoxypropoxypropanol "water soluble CARBITOL" solvents or CELLOSOLVE "water soluble solvents. The water-soluble CARBITOL solvents are compounds of the class 2- (2-alkoxyethoxy) ethanol in which the alkoxy group is derived from et-1-propyl or butyl, A water-soluble carbitol which is preferred is 2- (2 -butoxyethoxy) ethanol "also known as buti learbi tol. CELLOSOLVE" water-soluble solvents are compounds of class 2-alkoxyethoxyethanol, 2-butoxyethoxyethanol being preferred. Other suitable solvents are benzyl alcohol, methane, ethanol, isopropyl alcohol, and diols such as 2-ethyl-l-3-hexanediol and 2 »2» 4-t-imet-1, 3-pentanediol and mixtures thereof. The solvents that are preferred to be used here are n-butoxypropoxypropanol, butyl, Icarbi tol, benzyl alcohol, iscopropanol and mixtures thereof. The solvents that are most preferred to use here are buti! cabi tol ", benzyl alcohol and isopropanol Solvents may typically be present in the compositions of the invention at a level of up to 15% by weight, preferably from 2% to 7% by weight of the composition. further comprising a variety of other optional ingredients such as pH regulators (e.g., borate pH regulators), detergency builders, stabilizers, bleach activators, soil suspending agents, dye transfer agents, abriters, perfumes , anti-dusting agents, enzymes, dispersants »dye transfer inhibitors, pigments, perfumes and dyes.

Packaging Form of the Compositions The compositions herein can be packaged in a variety of suitable detergent packages known to those skilled in the art. The liquid compositions herein can be desirably packaged in manually operated spray dispensing containers which are usually made of organic and synthetic polymer plastic materials, and preferably in a trigger spray dispenser or pump spray dispenser. Said spray-type dispensers allow the liquid disinfectant compositions of the present invention to be applied uniformly to a relatively large area of a surface to be disinfected, thus contributing to the disinfecting properties of said compositions. Said spray-type dispensers are particularly suitable for disinfecting vertical surfaces. Spray-type dispensers suitable for use in accordance with the present invention include manually operated trigger-type foam dispensers sold for example by Specialty PacKaging Products, Inc. or Continental Sprayers, Inc. These types of dispensers are described, for example, in the US. -4,701,311 to Dunning and others, and EU-4,646,973 and EU-4,538,745 both to Focarracci. It is particularly preferred to use here spray dispensers such as T 8500"or T 8900" commercially available from Continental Spray International or T SlOO "commercially available from Canyon, Northern Ireland In said dispenser» the liquid composition is divided into small drops liquid and fine that result in a spray that is directed on the surface to be treated, in fact "in said spray-type dispenser" the composition contained in the body of said dispenser is directed through the head of the spray-type dispenser by means of an energy communicated with a pumping mechanism by the user while said user activates said pumping mechanism, very particularly »in said head of the spray-type dispenser» the composition is forced against an obstacle »eg a grate or a cone or similar »thus providing shocks to help atomize the liquid composition» that is to help the formation of of small drops of liquid. The compositions of the present invention can also be applied in the form of rags. By "rags" is meant here disposable towels impregnated with a liquid composition according to the present invention. Preferably, said rags are packed in a plastic box. The advantage of this embodiment is a faster use of a disinfectant composition by the user. This even outside the home, ie, it is not necessary to pour the liquid compositions in accordance with the present invention overlays the surfaces that will be treated / disinfected and dried with a cloth. In other words, the rags allow the disinfection of surfaces in one step.

Desfection procedure: The present invention encompasses a method of disinfecting a surface "wherein a composition comprising a peroxygen bleach, an amphoteric surfactant, glutaraldehyde and an antimicrobial essential oil or an active ingredient of the surface is applied to said surface. same. By "surface" is meant herein any surface, including an animated surface such as human skin, mouth, teeth and inanimate surfaces. The surfaces. inanimate include, but are not limited to »hard surfaces typically found in homes» such as kitchens »bathrooms or car interiors, for example, tiles, walls, floors, chrome, glass, smooth vinyl» any plastic, plasticized wood, uppers of tables, sinks, tableware »sanitary ware such as sinks, showers, shower curtains, toilets and the like» as well as on fabrics including »curtains» upholstery »white» tablecloths, sleeping bags, tents, furniture upholstered and similar, and carpets. The inanimate surfaces also include household items that include, but are not limited to, »refrigerators, freezers,» washing machines, »automatic dryers, ovens, microwave ovens, dishwashers and so on. In the process according to the present invention, said composition is applied in its concentrated form or after it has been diluted with water.

Preferably said composition is diluted up to 100 times its weight of water, preferably in SO to 40 times its weight of water, and most preferably 60 to 30 times, before being applied to said surface. In the preferred embodiment of the process of the present invention wherein said composition is applied to a hard surface that will be disinfected in its diluted form, "it is not necessary to rinse the surface after the composition has been applied" in fact there are no substantial residues. visible residues on said surface. The present invention will be further illustrated by means of the following examples.

EXAMPLES The following compositions were made by mixing the ingredients listed in the proportions listed (percentages by weight unless otherwise specified). These compositions were tested for prEN 1276 dirt conditions (0.3% albumin / hard water) of the European Normity Committee. These compositions provide excellent disinfection when used diluted or concentrated, eg, at dilution levels of 1: 100, 1:25, 1:50, on heavily soiled surfaces, while providing excellent surface safety.

Compositions 1 11 m IV V VI Hydrogen peroxide 7.0 6.0 7.0 2.0 7.0 1.0 Betaine- * 4.5 4.0 3.0 0.1 6.0 0.2 Uncle! - 0.5 Gl utaral dehyde 0.8 0.8 0.5 0.05 0.8 0.15 Eugenol 0.5 - - 0.02 0.5 - Geranium! - - 1.0 - - 0.2 Water and comp. Minor -Up to 100% H_.50 ^ up to pH 4.0 Compositions VII VIII IX X XI XII Hydrogen peroxide 7.0 6.0 3.5 2.0 7.0 1.0 Betaine- * 4.5 4.0 3.0 0.1 6.0 0.2 Glutaraldehyde O.B O.B 0.5 0.5 0.8 0.15 (Timo1 / Eugeno1 / 2.0 3.0 1.5 1.0 3.0 1.0 Geranium!) Water and comp. minor HßSO ^ up to pH 4.0 Compositions XIII XIV XV XVI XVII XVIII Hydrogen peroxide 7.0 6.0 7.0 2.0 7.0 1.0 Non-ionic surfactant ** 1 * '1 1.2 2.0 1.1 0.5 1.2 - Tensioacti or non-ionic **? *,? * < ? 1.6 - - 0.7 1.5 0.4 Betaine * - 4.5 4.0 3.0 0.1 6.0 0.2 Thymus! - 0.5 Gl Litara! Dehyde 0.8 0.8 0.5 0.5 0.8 0.15 Eugenol 0.5 0.05 0.5 __ Geraniol 1.0 0.2 Water and comp. Minor -Up to 100% - H_.SO ^ up to pH 4.0 Compositions XIX XX XXI XXII XXIII XXIV Hydrogen peroxide 7.0 6.0 7.0 2.0 7.0 1.0 Non-ionic surfactant **** 1.2 2.0 1.1 0.5 1.2 Non-ionic surfactant ****** 1.6 0.7 1.5 0.4 CIO Amine Oxide l.O 2.0 1.0 0.5 CIO Alkyl Sulfate - 4.5 3.0 1.5 Betaine * - 4.5 4.0 3.0 0.1 6.0 0.2 Thymus! 0.5 Glu tara! Dehide O.8 0.8 O.5 O.5 O.B O.15 Eugenol 0.5 0.05 0.5 Geranium! 1.0 - 0.2 Water and comp. Minor -Up to 100% - H-.SO ^ up to pH 4.0 Compositions XXV XXVI XXVII XXVIII XXIX Hydrogen peroxide 7. O 1.0 2.0 2.0 3.5 CIO amine oxide 4.5 0.2 0.8 0.8 3.0 Gl taraldehyde 0.8 0.15 0.2 0.2 0.5 Thymus! - __ 0.2 0.01 __ Eugenol 0.5 Geranium! 0.2 0.3 0.02 (Ti nol / Eugenol / Geranium!) 1.5 Water and comp. minor Up to 100% HaSO ^ up to pH 4.0 Betaine * is either commercially available coconut betaine from Seppic under the trade name Amonil 265"or lauri 1 etain commercially available from Albright &ilson under the trade name Empigen BB / L" or mixtures from the same. **** is Dobanol 23.3"****** is Dobanol 91. O"

Claims (15)

NOVELTY OF THE INVENTION CLAIMS

1. A de-fecting composition comprising a peroxygen bleach, an amphoteric surfactant, glutaraldehyde and an antimicrobial essential oil or an active substance thereof.

2. A composition according to claim 1, further characterized in that said "hydrogen peroxide bleach" or a water-soluble source thereof selected from the group consisting of percarbonates, pers-cates, persulfates, perborates, peroxygen, acids, dialkyoperoxides, diacides, peroxides, preformed percarboxylic acids, organic and inorganic peroxides, organic and inorganic hydroperoxides and mixtures thereof, and preferably is hydrogen peroxide.

3. A composition according to any of the preceding claims, further characterized in that said amphoteric surfactant is a betaine or sulfobetaine surfactant according to the formula: where Rl is a radica! alkyl containing from 1 to 24 carbon atoms, preferably from 8 to 18 and very preferably from 12 to 14, wherR2 and R3 contain from 1 to 3 carbon atoms and preferably 1 carbon atom, whern is a whole from 1 to 10 »preferably from 1 to 6 and most preferably is 1» Y is selected from the group consisting of carboxyl radicals and their "'foni! o' and wherthe sum of the radicals Rl» R2 and R3 is 14 to 24 carbon atoms and / or an amine oxide according to the formula RAR2R3N0 whereach of R1 »R2 and R3 is independently a straight or branched and saturated hydrocarbon chain containing from 1 to 30 carbon atoms» preferred from 6 to 20, and wherR2 and R3 are linear or branched hydrocarbon chains independently or substituted or unsubstituted containing from 1 to 4 carbon atoms, preferably from 1 to 3 carbon atoms and most preferably are methyl groups. .- A composition in accordance with which of the preceding claims »also characterized in that said antimicrobial essential oil is obtained from thyme» lemon grass (Cy bopagon citratus). citrus fruits »Rudolves» oranges »anise» cloves »anise seed» cinnamon »geranium» roses »lavender» citronella »eucalyptus» mint »camphor» sandalwood and cedar and mixtures thereof »and / or characterized further because said active essential oils they are selected from the group consisting of thymus! »eugenol» mertol »cedar!» verbenone »eucalyptol» anethole »pinocarvone» carvacrol »geranium!» hinoquitiol »berberine» terpineol, limsnene, rstania and mixtures thereof, and preferably is eugenol » verbenone »geranium!» eucalyptol. limonene and / or thymus !. 5. A composition according to any of the preceding claims "further characterized in that said composition comprises at least 0.O03% by weight of the total composition of said antimicrobial or active essential oil thereof, or mixtures thereof, preferably from 0.006% to 10% and most preferably from O.01% to 4%. 6. A composition according to any of the preceding claims, further characterized in that said composition comprises at least 0.01% by weight of the total composition of said peroxygen bleach or mixtures thereof »preferably from 0.1% to 15% and very preferably from 1% to 10%. 7. A composition according to any of the preceding claims, further characterized in that said composition comprises at least 0.005% by weight of the total composition of said amphoteric surfactant or mixtures thereof, preferably from 0.O% to 10% by weight. % and most preferably from 0.1% to 5%. 8. A composition according to any of the preceding claims, further characterized in that said composition comprises at least 0.003% by weight of the total composition! of glutaraldehyde, preferably from 0.008% to 4% and most preferably from 0.2% to 2%. 9. A composition according to any of the preceding indications, further characterized in that said composition further comprises a chelating agent selected from the group consisting of phosphonate chelating agents, aminophosphonate chelating agents, substituted heteroaromatic chelating agents, aminocarboxylate chelating agents, other carboxylate chelating agents, optionally substituted polyacrylating agent chelating agents. , eti lendiamino-, NT r-disuccinic and mixtures of Cough themselves. 10. A composition according to any of the preceding claims, further characterized in that said composition further comprises at least one optional ingredient selected from the group consisting of surfactants, radical scavengers, solvents »builders» stabilizers »Bleaching activators» soil suspending agents »agents for the transfer of dyes» brighteners. anti dusting agents. enzymes »dispersants» dye transfer inhibitors »pigments» perfumes »dyes and mixtures of Coughs themselves. 11. A composition according to any of the preceding claims "further characterized in that said composition is a liquid composition" preferably a liquid and aqueous composition with a pH preferably of not more than 12", most preferably from 3.5 to 7. 12.- A composition according to claim 11 further characterized in that said composition is packed in a spray dispenser. 13. An impregnated cloth with a composition according to claim 11. 1

4. A method for disinfecting a surface »further characterized in that a composition according to any of the preceding claims 1 to 12 is applied on said surface. 1

5. A method according to claim 14 »further characterized in that said composition is applied on said surface after having been diluted up to 100 times its weight of water, preferably 80 to 40 times its weight of water and very preferably 60. to 30 times.