MXPA06001050A - Sales de tartrato de 2-metoximetil -3-(3, 4-diclorofenil) -8-azabiciclo [3.2.1] octano. - Google Patents

Sales de tartrato de 2-metoximetil -3-(3, 4-diclorofenil) -8-azabiciclo [3.2.1] octano.

Info

Publication number
MXPA06001050A
MXPA06001050A MXPA06001050A MXPA06001050A MXPA06001050A MX PA06001050 A MXPA06001050 A MX PA06001050A MX PA06001050 A MXPA06001050 A MX PA06001050A MX PA06001050 A MXPA06001050 A MX PA06001050A MX PA06001050 A MXPA06001050 A MX PA06001050A
Authority
MX
Mexico
Prior art keywords
azabicyclo
dichlorophenyl
methoxymethyl
salts
tartrate salts
Prior art date
Application number
MXPA06001050A
Other languages
English (en)
Inventor
Klaus Snej Jensen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Priority claimed from PCT/EP2004/051651 external-priority patent/WO2005011694A1/en
Publication of MXPA06001050A publication Critical patent/MXPA06001050A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Esta invencion se relaciona con las novedosas sales de tartrato de (1R, 2R, 3S, 5S)-2 -metoximetil-3-(3, 4-diclorofenil) -8-azabiciclo [3.2.1]octano, tales como las L-tartrato monohidratadas y anhidras. Las sales son utiles como inhibidores de re-captacion de neurotransmisores monoamina. En otros aspectos la invencion se relaciona con el uso de estas sales en un metodo de terapia y con composiciones farmaceuticas que incluyen las sales de la invencion.
MXPA06001050A 2003-07-31 2004-07-29 Sales de tartrato de 2-metoximetil -3-(3, 4-diclorofenil) -8-azabiciclo [3.2.1] octano. MXPA06001050A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200301117 2003-07-31
US49409003P 2003-08-12 2003-08-12
PCT/EP2004/051651 WO2005011694A1 (en) 2003-07-31 2004-07-29 2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octane tartrate salts

Publications (1)

Publication Number Publication Date
MXPA06001050A true MXPA06001050A (es) 2006-04-24

Family

ID=34117517

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA06001050A MXPA06001050A (es) 2003-07-31 2004-07-29 Sales de tartrato de 2-metoximetil -3-(3, 4-diclorofenil) -8-azabiciclo [3.2.1] octano.

Country Status (9)

Country Link
KR (1) KR20060054386A (es)
CO (1) CO5640088A2 (es)
CY (1) CY1107639T1 (es)
HK (1) HK1089968A1 (es)
HR (1) HRP20070197T3 (es)
IL (1) IL172576A0 (es)
IS (1) IS2588B (es)
MX (1) MXPA06001050A (es)
NO (1) NO20060934L (es)

Also Published As

Publication number Publication date
HK1089968A1 (en) 2006-12-15
CO5640088A2 (es) 2006-05-31
NO20060934L (no) 2006-04-28
CY1107639T1 (el) 2013-04-18
KR20060054386A (ko) 2006-05-22
IS8330A (is) 2006-02-27
IL172576A0 (en) 2006-04-10
HRP20070197T3 (en) 2007-06-30
IS2588B (is) 2010-02-15

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