MXPA05013717A - Derivados de acido 2-etoxi-2-fenilpropionico para el tratamiento de trastornos de lipido. - Google Patents

Derivados de acido 2-etoxi-2-fenilpropionico para el tratamiento de trastornos de lipido.

Info

Publication number
MXPA05013717A
MXPA05013717A MXPA05013717A MXPA05013717A MXPA05013717A MX PA05013717 A MXPA05013717 A MX PA05013717A MX PA05013717 A MXPA05013717 A MX PA05013717A MX PA05013717 A MXPA05013717 A MX PA05013717A MX PA05013717 A MXPA05013717 A MX PA05013717A
Authority
MX
Mexico
Prior art keywords
lipid disorders
ethoxy
treatment
acid derivatives
phenylpropionic acid
Prior art date
Application number
MXPA05013717A
Other languages
English (en)
Inventor
Eva-Lotte Lindstedt-Alstermark
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MXPA05013717A publication Critical patent/MXPA05013717A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/64Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66Methanesulfonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un compuestos de la formula (I) en donde T representa O, S o NR y en donde R representa H, un grupo alquilo de 1 a 6 atomos de carbono o un grupo fenilalquilo de 1 a 6 atomos de carbono y sales farmaceuticamente aceptables de los mismos, procedimientos para preparar dichos compuestos, su utilidad en el tratamiento de condiciones clinicas incluyendo trastornos de lipido (dislipidemias), asociadas o no asociadas con resistencia a insulina, metodos para su uso terapeutico y composiciones farmaceuticas que los contienen (ver formula A).
MXPA05013717A 2003-06-18 2004-06-16 Derivados de acido 2-etoxi-2-fenilpropionico para el tratamiento de trastornos de lipido. MXPA05013717A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0314078.7A GB0314078D0 (en) 2003-06-18 2003-06-18 Therapeutic agents
PCT/GB2004/002619 WO2004113276A1 (en) 2003-06-18 2004-06-16 2-ethoxy-3-phenylpropionic acid derivatives for the treatment of lipid disorders

Publications (1)

Publication Number Publication Date
MXPA05013717A true MXPA05013717A (es) 2006-03-08

Family

ID=27636749

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05013717A MXPA05013717A (es) 2003-06-18 2004-06-16 Derivados de acido 2-etoxi-2-fenilpropionico para el tratamiento de trastornos de lipido.

Country Status (23)

Country Link
US (1) US7309720B2 (es)
EP (1) EP1638926A1 (es)
JP (1) JP2006527752A (es)
KR (1) KR20060030043A (es)
CN (1) CN1835916A (es)
AR (1) AR044827A1 (es)
AU (1) AU2004249494B2 (es)
BR (1) BRPI0411579A (es)
CA (1) CA2529253A1 (es)
CO (1) CO5650239A2 (es)
GB (1) GB0314078D0 (es)
IL (1) IL172377A0 (es)
IS (1) IS8225A (es)
MX (1) MXPA05013717A (es)
MY (1) MY137679A (es)
NO (1) NO20055889L (es)
RU (1) RU2005141067A (es)
SA (1) SA04250194B1 (es)
TW (1) TW200502202A (es)
UA (1) UA81810C2 (es)
UY (1) UY28368A1 (es)
WO (1) WO2004113276A1 (es)
ZA (1) ZA200510254B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA104987C2 (uk) * 2001-06-12 2014-04-10 Уеллстат Терепьютікс Корпорейшн Похідні 3-(2,6-диметилбензилокси)фенілоцтової кислоти
SE0104333D0 (sv) 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents
DK1517883T3 (da) 2002-06-20 2008-05-26 Astrazeneca Ab Ortho-substituerede benzoesyrederivater til behandling af insulinresistens

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801992D0 (sv) 1998-06-04 1998-06-04 Astra Ab New 3-aryl-2-hydroxypropionic acid derivative I
MA26634A1 (fr) 1998-06-04 2004-12-20 Astra Ab Nouveaux derives de l'acide 3-aryl propionique et analogues

Also Published As

Publication number Publication date
US20060178432A1 (en) 2006-08-10
US7309720B2 (en) 2007-12-18
IS8225A (is) 2006-01-10
MY137679A (en) 2009-02-27
UA81810C2 (uk) 2008-02-11
ZA200510254B (en) 2007-04-25
BRPI0411579A (pt) 2006-08-08
AR044827A1 (es) 2005-10-05
GB0314078D0 (en) 2003-07-23
KR20060030043A (ko) 2006-04-07
EP1638926A1 (en) 2006-03-29
NO20055889L (no) 2006-01-12
WO2004113276A1 (en) 2004-12-29
TW200502202A (en) 2005-01-16
SA04250194B1 (ar) 2008-06-02
CA2529253A1 (en) 2004-12-29
RU2005141067A (ru) 2006-07-27
AU2004249494A1 (en) 2004-12-29
CO5650239A2 (es) 2006-06-30
UY28368A1 (es) 2005-01-31
AU2004249494B2 (en) 2008-03-20
IL172377A0 (en) 2009-02-11
JP2006527752A (ja) 2006-12-07
CN1835916A (zh) 2006-09-20

Similar Documents

Publication Publication Date Title
MXPA05013712A (es) Derivados de acido propionico, utiles en el tratamiento de trastornos de lipidos.
TWI255807B (en) Therapeutic agents
TW200508180A (en) Therapeutic agents
BG108318A (en) Carboxamide-substituted phenylurea derivatives and method for the production and use thereof as medicaments
SE0202462D0 (sv) Novel use
MXPA05012415A (es) Inhibidores de glutamina fructosa-3-fosfato amidotransferasa (gfat).
TW200502230A (en) Dual nk1/nk3 derivatives
MX2009006742A (es) Inhibidores acilaminopirazoles como fgfr.
UA85708C2 (ru) Лекарственные комбинации, содержащие бензоксазины, для лечения заболеваний дыхательных путей
NO20065904L (no) Terapeutiske forbindelser
UA86977C2 (ru) Производные гидантоина для лечения обструктивных болезней дыхательных путей
SE9901573D0 (sv) New compounds
MY140630A (en) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
TW200504029A (en) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
TW200640465A (en) New pharmaceutically active compounds for the treatment of respiratory diseases
TW200626581A (en) Compounds, compositions containing them, preparation thereof and uses thereof
MY124727A (en) Tri-substituted phenyl derivatives and analogues.
UA83832C2 (ru) Производные бензимидазола, фармацевтическая композиция, которая их содержит, способ их получения и их применение
NO20053805L (no) Diarylmetylindenpiperidinderivater, framgangsmate for fremstilling derav, og anvendelse derav
CA2470066A1 (en) 3-phenyl-2-arylalkylthiopropionic acid derivatives as selective agonists of ppar-alpha
MXPA05013717A (es) Derivados de acido 2-etoxi-2-fenilpropionico para el tratamiento de trastornos de lipido.
SE0101978D0 (sv) New compounds
NO20045353L (no) Orto-substituerte benzosyrederivater for behandling av insulinresistens
MXPA04012685A (es) Derivados de acido benzoico orto-sustituidos para el tratamiento de la resistencia a la insulina.
TW200510313A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof

Legal Events

Date Code Title Description
FA Abandonment or withdrawal