MXPA05013715A - Proceso para preparar derivados del acido (2s)-3-(4- {2-[amino]-2 -oxoetoxi} fenil)-2- [amino]-2 -oxoetoxi}fenil)-2 -etoxipropanoico. - Google Patents

Proceso para preparar derivados del acido (2s)-3-(4- {2-[amino]-2 -oxoetoxi} fenil)-2- [amino]-2 -oxoetoxi}fenil)-2 -etoxipropanoico.

Info

Publication number
MXPA05013715A
MXPA05013715A MXPA05013715A MXPA05013715A MXPA05013715A MX PA05013715 A MXPA05013715 A MX PA05013715A MX PA05013715 A MXPA05013715 A MX PA05013715A MX PA05013715 A MXPA05013715 A MX PA05013715A MX PA05013715 A MXPA05013715 A MX PA05013715A
Authority
MX
Mexico
Prior art keywords
oxoethoxy
phenyl
amino
preparing
processes
Prior art date
Application number
MXPA05013715A
Other languages
English (en)
Inventor
Emmanuel Macedo
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MXPA05013715A publication Critical patent/MXPA05013715A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
    • C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invencion proporciona un proceso para la preparacion de un compuesto de la formula I, en el cual un compuesto de la formula II en donde R es H u OR representa un grupo protector para un grupo hidroxi carboxilico, se hace reaccionar con un compuesto de la formula III C6H13X, en donde X es un grupo saliente, en presencia de una base en presencia de un disolvente inerte, a una temperatura en el rango de -25 a 150OC y, opcionalmente, cuando OR representa un grupo protector, remover el grupo protector.
MXPA05013715A 2003-06-18 2004-06-16 Proceso para preparar derivados del acido (2s)-3-(4- {2-[amino]-2 -oxoetoxi} fenil)-2- [amino]-2 -oxoetoxi}fenil)-2 -etoxipropanoico. MXPA05013715A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0314134.8A GB0314134D0 (en) 2003-06-18 2003-06-18 Therapeutic agents
PCT/SE2004/000966 WO2004110982A1 (en) 2003-06-18 2004-06-16 Processes for preparing (2s)-3-(4-{2-[amino]-2-oxoethoxy}phenyl)-2-ethoxypropanoic acid derivatives

Publications (1)

Publication Number Publication Date
MXPA05013715A true MXPA05013715A (es) 2006-03-08

Family

ID=27636793

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05013715A MXPA05013715A (es) 2003-06-18 2004-06-16 Proceso para preparar derivados del acido (2s)-3-(4- {2-[amino]-2 -oxoetoxi} fenil)-2- [amino]-2 -oxoetoxi}fenil)-2 -etoxipropanoico.

Country Status (14)

Country Link
US (1) US20060142392A1 (es)
EP (1) EP1638920A1 (es)
JP (1) JP3822901B1 (es)
KR (1) KR20060065583A (es)
CN (1) CN1809528A (es)
AU (1) AU2004247612A1 (es)
BR (1) BRPI0411558A (es)
CA (1) CA2528933A1 (es)
GB (1) GB0314134D0 (es)
IL (1) IL172169A0 (es)
MX (1) MXPA05013715A (es)
NO (1) NO20055924L (es)
WO (1) WO2004110982A1 (es)
ZA (1) ZA200510248B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0314079D0 (en) * 2003-06-18 2003-07-23 Astrazeneca Ab Therapeutic agents
SE0104334D0 (sv) * 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents
GB0229931D0 (en) * 2002-12-21 2003-01-29 Astrazeneca Ab Therapeutic agents
WO2007004957A1 (en) * 2005-07-05 2007-01-11 Astrazeneca Ab Novel crystalline form
AR055073A1 (es) * 2005-07-11 2007-08-01 Astrazeneca Ab Agentes terapeuticos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6353023B1 (en) * 1997-08-28 2002-03-05 Pharmacia & Upjohn Company Inhibitors of protein tyrosine phosphatase
US6410585B1 (en) * 1997-08-28 2002-06-25 Scott D. Larsen Inhibitors of protein tyrosine phosphatase
SE0104333D0 (sv) * 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents
SE0104334D0 (sv) * 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents

Also Published As

Publication number Publication date
AU2004247612A1 (en) 2004-12-23
KR20060065583A (ko) 2006-06-14
EP1638920A1 (en) 2006-03-29
BRPI0411558A (pt) 2006-08-01
CN1809528A (zh) 2006-07-26
JP3822901B1 (ja) 2006-09-20
US20060142392A1 (en) 2006-06-29
WO2004110982A1 (en) 2004-12-23
ZA200510248B (en) 2006-12-27
GB0314134D0 (en) 2003-07-23
NO20055924L (no) 2006-01-05
IL172169A0 (en) 2009-02-11
JP2006527768A (ja) 2006-12-07
CA2528933A1 (en) 2004-12-23

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