MXPA05012319A - Suministro de compuestos con celulas sanguineas rehidratadas. - Google Patents

Suministro de compuestos con celulas sanguineas rehidratadas.

Info

Publication number
MXPA05012319A
MXPA05012319A MXPA05012319A MXPA05012319A MXPA05012319A MX PA05012319 A MXPA05012319 A MX PA05012319A MX PA05012319 A MXPA05012319 A MX PA05012319A MX PA05012319 A MXPA05012319 A MX PA05012319A MX PA05012319 A MXPA05012319 A MX PA05012319A
Authority
MX
Mexico
Prior art keywords
blood cells
delivery
compounds
same
rehydrated blood
Prior art date
Application number
MXPA05012319A
Other languages
English (en)
Inventor
Marjorie S Read
Original Assignee
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina filed Critical Univ North Carolina
Publication of MXPA05012319A publication Critical patent/MXPA05012319A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0215—Disinfecting agents, e.g. antimicrobials for preserving living parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/905—Specially adapted for travel through blood circulatory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Se describen celulas sanguineas fijadas-secas que portan un agente activo, junto con metodos para hacer las mismas, metodos para utilizar las mismas, y composiciones que contienen a las mismas; las celulas sanguineas pueden ser globulos rojos o plaquetas sanguineas.
MXPA05012319A 2003-05-16 2004-05-14 Suministro de compuestos con celulas sanguineas rehidratadas. MXPA05012319A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US47100503P 2003-05-16 2003-05-16
US53305903P 2003-12-29 2003-12-29
US10/845,045 US7294455B2 (en) 2003-05-16 2004-05-13 Fixed-dried platelets cross-linked to protein
PCT/US2004/015320 WO2005021706A2 (en) 2003-05-16 2004-05-14 Delivery of compounds with rehydrated blood cells

Publications (1)

Publication Number Publication Date
MXPA05012319A true MXPA05012319A (es) 2006-01-30

Family

ID=34279762

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05012319A MXPA05012319A (es) 2003-05-16 2004-05-14 Suministro de compuestos con celulas sanguineas rehidratadas.

Country Status (7)

Country Link
US (5) US7294455B2 (es)
EP (1) EP1624752A4 (es)
JP (1) JP2006525810A (es)
CN (1) CN1822765B (es)
CA (1) CA2525374A1 (es)
MX (1) MXPA05012319A (es)
WO (1) WO2005021706A2 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7294455B2 (en) * 2003-05-16 2007-11-13 The University Of North Carolina At Chapel Hill Fixed-dried platelets cross-linked to protein
US8277837B2 (en) 2006-01-11 2012-10-02 Entegrion, Inc. Hemostatic textile
US20070178107A1 (en) * 2006-01-31 2007-08-02 Awdalla Essam T Method and means for treating solid tumors
CN104998257A (zh) * 2007-04-06 2015-10-28 武田疫苗公司 用于活的减毒病毒的方法和组合物
US8512697B2 (en) * 2007-05-16 2013-08-20 The University Of North Carolina At Chapel Hill Delivery of micro- and nanoparticles with blood platelets
WO2009111615A2 (en) 2008-03-05 2009-09-11 Thrombovision, Inc. Systems for measuring properties of a physiological fluid suspension
US10117428B2 (en) 2013-07-17 2018-11-06 Rythrx Therapeutics, Llc Compositions and methods for preserving donated blood
US9919002B2 (en) 2013-10-21 2018-03-20 North Carolina State University Methods and constructs for compound delivery
WO2015109220A1 (en) * 2014-01-17 2015-07-23 President And Fellows Of Harvard College Platelet decoy and use thereof
JP6659591B2 (ja) 2014-06-09 2020-03-04 テルモ ビーシーティー、インコーポレーテッド 凍結乾燥
WO2016023008A1 (en) * 2014-08-07 2016-02-11 The General Hospital Corporation Platelet-targeted microfluidic isolation of cells
CA3005311A1 (en) * 2014-11-14 2016-05-19 Cellphire, Inc. Products and devices for controlling and stopping bleeding and methods of using
CN109890420B (zh) * 2016-09-13 2024-04-09 北卡罗来纳州立大学 用于递送治疗剂的血小板组合物和方法
LT3548092T (lt) * 2016-11-30 2022-10-10 University Of Miami Rmd kompozicija ir panaudojimo būdai
US10793327B2 (en) 2017-10-09 2020-10-06 Terumo Bct Biotechnologies, Llc Lyophilization container and method of using same
CA3121484A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets loaded with anti-cancer agents
US11767511B2 (en) 2018-11-30 2023-09-26 Cellphire, Inc. Platelets as delivery agents
CA3130670A1 (en) 2019-03-14 2020-09-17 Terumo Bct Biotechnologies, Llc Lyophilization loading tray assembly and system
AU2020267368B2 (en) 2019-05-03 2023-05-04 Cellphire, Inc. Materials and methods for producing blood products
AU2020334903B2 (en) 2019-08-16 2023-12-21 Cellphire, Inc. Thrombosomes as an antiplatelet agent reversal agent
WO2021158646A1 (en) 2020-02-04 2021-08-12 Cellphire, Inc. Treatment of von willebrand disease
CN112656763B (zh) * 2020-12-29 2022-07-15 吉林大学 一种基于剪切力响应的载药纳米胶束的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU650045B2 (en) * 1990-09-12 1994-06-09 Lifecell Corporation Method and apparatus for cryopreparation dry stabilization and rehydration of biological suspensions
ATE311438T1 (de) * 1992-05-29 2005-12-15 Univ North Carolina Im immobilisierten zustand getrocknete pharmazeutisch verträgliche menschliche blutplättchen
JPH08109142A (ja) * 1994-08-16 1996-04-30 S R L:Kk 血小板薬物送達システム
AR001654A1 (es) 1995-04-19 1997-11-26 Univ East Carolina Método para la descontaminacion microbiana de plaquetas sanguineas
US5891393A (en) * 1996-04-09 1999-04-06 The University Of North Carolina At Chapel Hill Method for the microbial decontamination of blood platelets
AT407484B (de) 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
WO1999034680A1 (en) 1998-01-06 1999-07-15 Trustees Of Boston University Decorated red blood cells
US6139878A (en) 1998-04-27 2000-10-31 Aventis Behring, Llc Method for preparing a diafiltered stabilized blood product
WO2001058266A1 (en) * 2000-02-10 2001-08-16 The Regents Of The University Of California Therapeutic platelets and methods
US6770478B2 (en) * 2000-02-10 2004-08-03 The Regents Of The University Of California Erythrocytic cells and method for preserving cells
JP2001333771A (ja) * 2000-03-24 2001-12-04 Olympus Optical Co Ltd 固相組織又は細胞の乾燥固定方法
WO2003020116A2 (en) * 2001-08-31 2003-03-13 University Of North Carolina At Chapel Hill Fixed-dried red blood cells
US7294455B2 (en) * 2003-05-16 2007-11-13 The University Of North Carolina At Chapel Hill Fixed-dried platelets cross-linked to protein
DE102004054536A1 (de) * 2004-11-06 2006-05-11 Capsulution Nanoscience Ag Multimodal veränderte Zellen als zellulare Darreichungsformen für aktive Substanzen und als diagnostische Zellpartikel

Also Published As

Publication number Publication date
US20120128647A1 (en) 2012-05-24
US20140065120A1 (en) 2014-03-06
EP1624752A4 (en) 2007-07-11
US20070212300A1 (en) 2007-09-13
CN1822765B (zh) 2011-08-17
CA2525374A1 (en) 2005-03-10
US7294455B2 (en) 2007-11-13
CN1822765A (zh) 2006-08-23
AU2004269308A1 (en) 2005-03-10
WO2005021706A3 (en) 2005-12-15
EP1624752A2 (en) 2006-02-15
JP2006525810A (ja) 2006-11-16
US7901674B2 (en) 2011-03-08
US20050025748A1 (en) 2005-02-03
AU2004269308B2 (en) 2009-09-17
US20050272161A1 (en) 2005-12-08
WO2005021706A2 (en) 2005-03-10
US8492081B2 (en) 2013-07-23

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