MXPA05004133A - Nuevos compuestos antitumorales. - Google Patents
Nuevos compuestos antitumorales.Info
- Publication number
- MXPA05004133A MXPA05004133A MXPA05004133A MXPA05004133A MXPA05004133A MX PA05004133 A MXPA05004133 A MX PA05004133A MX PA05004133 A MXPA05004133 A MX PA05004133A MX PA05004133 A MXPA05004133 A MX PA05004133A MX PA05004133 A MXPA05004133 A MX PA05004133A
- Authority
- MX
- Mexico
- Prior art keywords
- kahalaide
- methylhexanoic
- compound
- kahalalide
- antitumoral
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 abstract 2
- RCGXNDQKCXNWLO-WLEIXIPESA-N (2r)-n-[(2s)-5-amino-1-[[(2r,3r)-1-[[(3s,6z,9s,12r,15r,18r,19s)-9-benzyl-15-[(2r)-butan-2-yl]-6-ethylidene-19-methyl-2,5,8,11,14,17-hexaoxo-3,12-di(propan-2-yl)-1-oxa-4,7,10,13,16-pentazacyclononadec-18-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopent Chemical class N([C@@H](CCCN)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H]1C(N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)NC(/C(=O)N[C@H](C(=O)O[C@H]1C)C(C)C)=C\C)C(C)C)[C@H](C)CC)=O)C(=O)[C@H]1CCCN1C(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)CCCC(C)C)C(C)C)[C@@H](C)O)C(C)C)C(C)C RCGXNDQKCXNWLO-WLEIXIPESA-N 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 229930194861 kahalalide Natural products 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2002/004735 WO2003033012A1 (en) | 2001-10-19 | 2002-10-18 | Kahalalide compounds for use in cancer therapy |
| GBGB0304367.6A GB0304367D0 (en) | 2003-02-26 | 2003-02-26 | Methods for treating psoriasis |
| GB0314725A GB0314725D0 (en) | 2003-06-24 | 2003-06-24 | New antitumoral compounds |
| PCT/US2003/033207 WO2004035613A2 (en) | 2002-10-18 | 2003-10-20 | 4-methylhexanoic kahalaide f compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05004133A true MXPA05004133A (es) | 2005-10-05 |
Family
ID=32110555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05004133A MXPA05004133A (es) | 2002-10-18 | 2003-10-20 | Nuevos compuestos antitumorales. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1572726B1 (https=) |
| JP (1) | JP4430009B2 (https=) |
| CN (2) | CN100591691C (https=) |
| BR (1) | BR0315489A (https=) |
| CA (1) | CA2501089C (https=) |
| ES (1) | ES2357644T3 (https=) |
| MX (1) | MXPA05004133A (https=) |
| NZ (1) | NZ539093A (https=) |
| WO (1) | WO2004035613A2 (https=) |
| ZA (1) | ZA200502926B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6274551B1 (en) * | 1994-02-03 | 2001-08-14 | Pharmamar, S.A. | Cytotoxic and antiviral compound |
| GB0304367D0 (en) * | 2003-02-26 | 2003-04-02 | Pharma Mar Sau | Methods for treating psoriasis |
| US7507708B2 (en) | 2003-02-26 | 2009-03-24 | Pharma Mar, S.A.U. | Antitumoral compounds |
| GB0321066D0 (en) | 2003-09-09 | 2003-10-08 | Pharma Mar Sau | New antitumoral compounds |
| WO2009052379A2 (en) * | 2007-10-19 | 2009-04-23 | Pharma Mar, S.A. | Improved antitumoral treatments |
| DE102008005097B4 (de) * | 2008-01-18 | 2011-04-07 | Leibnitz-Institut für Meereswissenschaften | Antitumoraler Cyclodepsipeptide, deren Herstellung und Verwendung |
| CN101965192A (zh) * | 2008-03-07 | 2011-02-02 | 法马马有限公司 | 改善的抗肿瘤治疗 |
| WO2009135939A2 (en) * | 2008-05-09 | 2009-11-12 | Pharma Mar, S.A. | Depsipeptide for use in cancer therapy |
| ME02395B (me) | 2010-11-12 | 2016-09-20 | Pharma Mar Sa | Kombinovana terapija sa antitumorskim alkaloidima |
| HRP20231233T1 (hr) | 2017-04-27 | 2024-01-19 | Pharma Mar, S.A. | Antitumorski spojevi |
| JP2023503318A (ja) | 2019-11-21 | 2023-01-27 | ファルマ、マール、ソシエダード、アノニマ | ルルビネクテジン製剤で小細胞肺がんを処置する方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6178719A (ja) * | 1984-09-25 | 1986-04-22 | Tanabe Seiyaku Co Ltd | 総合輸液剤 |
| GB9302046D0 (en) * | 1993-02-03 | 1993-03-24 | Pharma Mar Sa | Antiumoral compound-v |
| US6274551B1 (en) * | 1994-02-03 | 2001-08-14 | Pharmamar, S.A. | Cytotoxic and antiviral compound |
| ES2256305T3 (es) * | 2000-10-31 | 2006-07-16 | Pharma Mar, S.A. | Formulaciones de kahalalide f. |
| WO2003033012A1 (en) * | 2001-10-19 | 2003-04-24 | Pharma Mar, S.A. | Kahalalide compounds for use in cancer therapy |
-
2003
- 2003-10-20 NZ NZ539093A patent/NZ539093A/en not_active IP Right Cessation
- 2003-10-20 JP JP2005501483A patent/JP4430009B2/ja not_active Expired - Fee Related
- 2003-10-20 CA CA2501089A patent/CA2501089C/en not_active Expired - Fee Related
- 2003-10-20 WO PCT/US2003/033207 patent/WO2004035613A2/en not_active Ceased
- 2003-10-20 CN CN200380101647A patent/CN100591691C/zh not_active Expired - Fee Related
- 2003-10-20 EP EP03779140A patent/EP1572726B1/en not_active Expired - Lifetime
- 2003-10-20 ES ES03779140T patent/ES2357644T3/es not_active Expired - Lifetime
- 2003-10-20 MX MXPA05004133A patent/MXPA05004133A/es active IP Right Grant
- 2003-10-20 CN CNA2007101122538A patent/CN101077885A/zh active Pending
- 2003-10-20 BR BR0315489-0A patent/BR0315489A/pt not_active IP Right Cessation
-
2005
- 2005-04-11 ZA ZA200502926A patent/ZA200502926B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2501089C (en) | 2012-07-17 |
| BR0315489A (pt) | 2005-08-23 |
| CA2501089A1 (en) | 2004-04-29 |
| ZA200502926B (en) | 2006-02-22 |
| WO2004035613A3 (en) | 2004-07-29 |
| EP1572726A2 (en) | 2005-09-14 |
| CN1705677A (zh) | 2005-12-07 |
| NZ539093A (en) | 2007-10-26 |
| CN101077885A (zh) | 2007-11-28 |
| ES2357644T3 (es) | 2011-04-28 |
| JP2006517195A (ja) | 2006-07-20 |
| EP1572726B1 (en) | 2010-12-08 |
| JP4430009B2 (ja) | 2010-03-10 |
| WO2004035613A2 (en) | 2004-04-29 |
| CN100591691C (zh) | 2010-02-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |