MXPA05003801A - Compuestos de 7,9-difluoro-5h-cromeno[3,4-f]quinolina 5-sustituida como moduladores selectivos de receptores de progesterona. - Google Patents
Compuestos de 7,9-difluoro-5h-cromeno[3,4-f]quinolina 5-sustituida como moduladores selectivos de receptores de progesterona.Info
- Publication number
- MXPA05003801A MXPA05003801A MXPA05003801A MXPA05003801A MXPA05003801A MX PA05003801 A MXPA05003801 A MX PA05003801A MX PA05003801 A MXPA05003801 A MX PA05003801A MX PA05003801 A MXPA05003801 A MX PA05003801A MX PA05003801 A MXPA05003801 A MX PA05003801A
- Authority
- MX
- Mexico
- Prior art keywords
- compound
- carbon atoms
- difluoro
- dihydro
- quinoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41796802P | 2002-10-11 | 2002-10-11 | |
| PCT/US2003/024420 WO2004033461A1 (en) | 2002-10-11 | 2003-08-04 | 5-SUBSTITUTED 7,9-DIFLUORO-5H-CHROMENO[3,4-f]QUINOLINE COMPOUNDS AS SELECTIVE PROGESTERONE RECEPTOR MODULATORS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05003801A true MXPA05003801A (es) | 2005-06-08 |
Family
ID=31994318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05003801A MXPA05003801A (es) | 2002-10-11 | 2003-08-04 | Compuestos de 7,9-difluoro-5h-cromeno[3,4-f]quinolina 5-sustituida como moduladores selectivos de receptores de progesterona. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7163946B2 (enExample) |
| EP (1) | EP1554283A1 (enExample) |
| JP (1) | JP2006504737A (enExample) |
| AR (1) | AR040781A1 (enExample) |
| AU (1) | AU2003258051A1 (enExample) |
| CA (1) | CA2501834A1 (enExample) |
| CL (1) | CL2003001545A1 (enExample) |
| DE (1) | DE20301728U1 (enExample) |
| HK (1) | HK1055059A2 (enExample) |
| MX (1) | MXPA05003801A (enExample) |
| TW (1) | TW200413384A (enExample) |
| WO (1) | WO2004033461A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566372B1 (en) | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
| US7026484B2 (en) | 2001-02-23 | 2006-04-11 | Ligand Pharmaceuticals Incorporated | Tricyclic androgen receptor modulator compounds and methods |
| DE20301728U1 (de) | 2002-10-11 | 2004-03-11 | Ligand Pharmaceuticals, Inc., San Diego | 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen |
| AR040783A1 (es) * | 2002-10-11 | 2005-04-20 | Ligand Pharm Inc | 5-(1',1'-cicloaquil/alquenil) metiliden-1,2 -dihidro-5-h-cromeno [3,4- f] quiinolinas como compuestos moduladores selectivos de receptores de progesterona |
| TW200410968A (en) | 2002-10-11 | 2004-07-01 | Ligand Pharm Inc | 5-cycloalkenyl 5H-chromeno[3,4-f]quinoline derivatives as selective progesterone receptor modulator compounds |
| MD3820874T2 (ro) * | 2018-07-12 | 2023-05-31 | Lilly Co Eli | Degradanți selectivi ai receptorului estrogen |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3635941A (en) | 1969-04-01 | 1972-01-18 | Eastman Kodak Co | Disperse mono azo dyes containing an acylamidotetrahydroquinoline group |
| US3907507A (en) | 1971-04-26 | 1975-09-23 | Heliodoro Monroy Rivera | Novel apparatus for the obtention of substituted 1,2-dihydroquinolines |
| DK0513387T3 (da) | 1990-11-30 | 2000-06-05 | Otsuka Pharma Co Ltd | Thiazolderivater som inhibitorer af aktivt oxygen |
| JPH04316557A (ja) | 1991-04-16 | 1992-11-06 | Kyorin Pharmaceut Co Ltd | ６−アリール環状アントラニル酸誘導体 |
| US5506102A (en) | 1993-10-28 | 1996-04-09 | Ligand Pharmaceuticals Incorporated | Methods of using the A form of the progesterone receptor to screen for antagonists of steroid intracellar receptor-mediated transcription |
| US5688808A (en) | 1994-12-22 | 1997-11-18 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
| AU717251B2 (en) | 1994-12-22 | 2000-03-23 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
| US6696459B1 (en) | 1994-12-22 | 2004-02-24 | Ligand Pharmaceuticals Inc. | Steroid receptor modulator compounds and methods |
| BR9710988A (pt) | 1996-06-27 | 2002-01-15 | Ligand Pharm Inc | Método e compostos moduladores receptores de androgênio |
| KR20010040935A (ko) * | 1998-02-13 | 2001-05-15 | 스티븐 에프. 웨인스톡 | 글루코코르티코이드 선택적인 소염제 |
| US6506766B1 (en) | 1998-02-13 | 2003-01-14 | Abbott Laboratories | Glucocortiocoid-selective antinflammatory agents |
| US6380207B2 (en) | 1998-02-13 | 2002-04-30 | Abbott Laboratories | Glucocortiocoid-selective antiinflammatory agents |
| US6093826A (en) | 1998-06-08 | 2000-07-25 | Ligand Pharmaceuticals Incorporated | Process for the preparation of C(5)-substituted 1,2-dihydro-5H-chromeno[3,4-f] quinolines |
| TW200410968A (en) | 2002-10-11 | 2004-07-01 | Ligand Pharm Inc | 5-cycloalkenyl 5H-chromeno[3,4-f]quinoline derivatives as selective progesterone receptor modulator compounds |
| AR040783A1 (es) | 2002-10-11 | 2005-04-20 | Ligand Pharm Inc | 5-(1',1'-cicloaquil/alquenil) metiliden-1,2 -dihidro-5-h-cromeno [3,4- f] quiinolinas como compuestos moduladores selectivos de receptores de progesterona |
| DE20301728U1 (de) | 2002-10-11 | 2004-03-11 | Ligand Pharmaceuticals, Inc., San Diego | 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen |
-
2003
- 2003-02-04 DE DE20301728U patent/DE20301728U1/de not_active Expired - Lifetime
- 2003-08-04 WO PCT/US2003/024420 patent/WO2004033461A1/en not_active Ceased
- 2003-08-04 AR AR20030102794A patent/AR040781A1/es not_active Application Discontinuation
- 2003-08-04 JP JP2004543233A patent/JP2006504737A/ja active Pending
- 2003-08-04 CA CA002501834A patent/CA2501834A1/en not_active Abandoned
- 2003-08-04 MX MXPA05003801A patent/MXPA05003801A/es unknown
- 2003-08-04 TW TW092121283A patent/TW200413384A/zh unknown
- 2003-08-04 HK HK03105598A patent/HK1055059A2/xx not_active IP Right Cessation
- 2003-08-04 CL CL200301545A patent/CL2003001545A1/es unknown
- 2003-08-04 EP EP03808052A patent/EP1554283A1/en not_active Withdrawn
- 2003-08-04 AU AU2003258051A patent/AU2003258051A1/en not_active Abandoned
- 2003-10-10 US US10/684,212 patent/US7163946B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7163946B2 (en) | 2007-01-16 |
| AR040781A1 (es) | 2005-04-20 |
| TW200413384A (en) | 2004-08-01 |
| AU2003258051A1 (en) | 2004-05-04 |
| WO2004033461A1 (en) | 2004-04-22 |
| CL2003001545A1 (es) | 2005-01-07 |
| HK1055059A2 (en) | 2003-12-05 |
| DE20301728U1 (de) | 2004-03-11 |
| EP1554283A1 (en) | 2005-07-20 |
| US20040152717A1 (en) | 2004-08-05 |
| CA2501834A1 (en) | 2004-04-22 |
| JP2006504737A (ja) | 2006-02-09 |
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