MXPA04003278A - Derivados de 5-metoxi-8-aril-?1,2,4?triazolo?1,5-a?piridina como antagonistas del receptor de adenosina. - Google Patents
Derivados de 5-metoxi-8-aril-?1,2,4?triazolo?1,5-a?piridina como antagonistas del receptor de adenosina.Info
- Publication number
- MXPA04003278A MXPA04003278A MXPA04003278A MXPA04003278A MXPA04003278A MX PA04003278 A MXPA04003278 A MX PA04003278A MX PA04003278 A MXPA04003278 A MX PA04003278A MX PA04003278 A MXPA04003278 A MX PA04003278A MX PA04003278 A MXPA04003278 A MX PA04003278A
- Authority
- MX
- Mexico
- Prior art keywords
- triazolo
- methoxy
- aryl
- receptor antagonists
- adenosine receptor
- Prior art date
Links
- 229940121359 adenosine receptor antagonist Drugs 0.000 title 1
- 239000000296 purinergic P1 receptor antagonist Substances 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 102000000506 Adenosine A2 Receptors Human genes 0.000 abstract 1
- 108010041368 Adenosine A2 Receptors Proteins 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Addiction (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01123949 | 2001-10-08 | ||
| PCT/EP2002/010917 WO2003031445A1 (en) | 2001-10-08 | 2002-09-28 | 5-methoxy-8-aryl-[1,2,4] triazolo [1,5-a] pyridine derivatives as adenosine receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04003278A true MXPA04003278A (es) | 2004-07-23 |
Family
ID=8178877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04003278A MXPA04003278A (es) | 2001-10-08 | 2002-09-28 | Derivados de 5-metoxi-8-aril-?1,2,4?triazolo?1,5-a?piridina como antagonistas del receptor de adenosina. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6693116B2 (OSRAM) |
| EP (1) | EP1436292B1 (OSRAM) |
| JP (1) | JP4101756B2 (OSRAM) |
| KR (1) | KR100604407B1 (OSRAM) |
| CN (1) | CN1254475C (OSRAM) |
| AR (1) | AR036735A1 (OSRAM) |
| AT (1) | ATE338043T1 (OSRAM) |
| AU (1) | AU2002338827B2 (OSRAM) |
| BR (1) | BR0213177A (OSRAM) |
| CA (1) | CA2462801A1 (OSRAM) |
| DE (1) | DE60214408T2 (OSRAM) |
| ES (1) | ES2269772T3 (OSRAM) |
| MX (1) | MXPA04003278A (OSRAM) |
| PL (1) | PL370565A1 (OSRAM) |
| RU (1) | RU2298009C2 (OSRAM) |
| WO (1) | WO2003031445A1 (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1830978B (zh) * | 2005-03-07 | 2010-06-16 | 中国人民解放军军事医学科学院毒物药物研究所 | 吡唑并[4,3-c]喹啉-3-酮化合物、其制备方法及其应用 |
| WO2009017954A1 (en) * | 2007-08-01 | 2009-02-05 | Phenomix Corporation | Inhibitors of jak2 kinase |
| GB0719803D0 (en) * | 2007-10-10 | 2007-11-21 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| CA2727036C (en) * | 2008-06-20 | 2017-03-21 | Genentech, Inc. | Triazolopyridine jak inhibitor compounds and methods |
| EP2296475A4 (en) | 2008-06-20 | 2014-03-05 | Genentech Inc | TRIAZOLOPYRIDINE COMPOUNDS JAK KINASE INHIBITORS AND METHODS |
| SG172206A1 (en) * | 2008-12-19 | 2011-07-28 | Leo Pharma As | Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases |
| BRPI1009637A2 (pt) | 2009-06-05 | 2019-04-30 | Cephalon, Inc | composto, composição e uso de um composto |
| UA112096C2 (uk) * | 2011-12-12 | 2016-07-25 | Байєр Інтеллектуал Проперті Гмбх | Заміщені триазолопіридини та їх застосування як інгібіторів ttk |
| IN2015DN00202A (OSRAM) * | 2012-07-12 | 2015-06-12 | Chiesi Farma Spa | |
| CN104768954B (zh) * | 2012-09-14 | 2017-11-17 | 美国陶氏益农公司 | 由4‑氨基‑2,5‑二甲氧基嘧啶制备2‑氨基‑5,8‑二甲氧基[1,2,4]三唑并[1,5‑c]嘧啶的改善方法 |
| PE20161323A1 (es) | 2013-09-05 | 2016-11-25 | Hoffmann La Roche | Compuestos de triazolopiridina, composiciones y metodos de uso de los mismos |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE287262C (OSRAM) * | ||||
| US6355653B1 (en) | 1999-09-06 | 2002-03-12 | Hoffmann-La Roche Inc. | Amino-triazolopyridine derivatives |
| US6514989B1 (en) * | 2001-07-20 | 2003-02-04 | Hoffmann-La Roche Inc. | Aromatic and heteroaromatic substituted 1,2,4-triazolo pyridine derivatives |
-
2002
- 2002-09-18 US US10/246,551 patent/US6693116B2/en not_active Expired - Fee Related
- 2002-09-28 WO PCT/EP2002/010917 patent/WO2003031445A1/en not_active Ceased
- 2002-09-28 RU RU2004114277/04A patent/RU2298009C2/ru not_active IP Right Cessation
- 2002-09-28 JP JP2003534428A patent/JP4101756B2/ja not_active Expired - Fee Related
- 2002-09-28 KR KR1020047005097A patent/KR100604407B1/ko not_active Expired - Fee Related
- 2002-09-28 CN CNB028199138A patent/CN1254475C/zh not_active Expired - Fee Related
- 2002-09-28 MX MXPA04003278A patent/MXPA04003278A/es active IP Right Grant
- 2002-09-28 CA CA002462801A patent/CA2462801A1/en not_active Abandoned
- 2002-09-28 ES ES02777254T patent/ES2269772T3/es not_active Expired - Lifetime
- 2002-09-28 AT AT02777254T patent/ATE338043T1/de not_active IP Right Cessation
- 2002-09-28 AU AU2002338827A patent/AU2002338827B2/en not_active Ceased
- 2002-09-28 BR BR0213177-3A patent/BR0213177A/pt not_active IP Right Cessation
- 2002-09-28 PL PL02370565A patent/PL370565A1/xx not_active Application Discontinuation
- 2002-09-28 DE DE60214408T patent/DE60214408T2/de not_active Expired - Fee Related
- 2002-09-28 EP EP02777254A patent/EP1436292B1/en not_active Expired - Lifetime
- 2002-10-04 AR ARP020103750A patent/AR036735A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1254475C (zh) | 2006-05-03 |
| PL370565A1 (en) | 2005-05-30 |
| RU2298009C2 (ru) | 2007-04-27 |
| AR036735A1 (es) | 2004-09-29 |
| BR0213177A (pt) | 2004-09-14 |
| CA2462801A1 (en) | 2003-04-17 |
| EP1436292A1 (en) | 2004-07-14 |
| WO2003031445A1 (en) | 2003-04-17 |
| ES2269772T3 (es) | 2007-04-01 |
| AU2002338827B2 (en) | 2007-09-06 |
| ATE338043T1 (de) | 2006-09-15 |
| KR100604407B1 (ko) | 2006-07-25 |
| DE60214408D1 (de) | 2006-10-12 |
| US6693116B2 (en) | 2004-02-17 |
| JP4101756B2 (ja) | 2008-06-18 |
| JP2005508954A (ja) | 2005-04-07 |
| RU2004114277A (ru) | 2006-01-10 |
| KR20040044196A (ko) | 2004-05-27 |
| CN1564821A (zh) | 2005-01-12 |
| DE60214408T2 (de) | 2007-03-08 |
| US20030134873A1 (en) | 2003-07-17 |
| EP1436292B1 (en) | 2006-08-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUP0102084A2 (hu) | Kinolinszármazékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyszerkészítmények | |
| PL373414A1 (en) | 8-methoxy-(1,2,4)triazolo(1,5-a)pyridine derivatives and their use as adenosine receptor ligands | |
| WO2003080580A3 (en) | Quinoline derivatives and their use as 5-ht6 ligands | |
| WO2003106428A8 (fr) | Derives d'arylsulfonamides et leur utilisation en tant que antagonistes au recepteur b1 de la bradykinine | |
| BG103785A (en) | Pyrrolo[2,3-d]pyrimidines and their application as tyrosine kinase inhibitors | |
| BG104248A (en) | Benzamidoxim derivatives, intermediate products and methods for preparing and using them as fungicides | |
| NZ512731A (en) | Tricyclic inhibitors of poly(ADP-ribose) polymerases | |
| CA2286723A1 (en) | Tricyclic compounds | |
| DE60039359D1 (de) | Amide als pyruvatdehydrogenaseinhibitoren | |
| DE60236719D1 (de) | Purinderivate als antagonisten an purinergen rezeptoren | |
| MXPA04003278A (es) | Derivados de 5-metoxi-8-aril-?1,2,4?triazolo?1,5-a?piridina como antagonistas del receptor de adenosina. | |
| MX2012008147A (es) | Derivados de pirrazolopiridina. | |
| MX2007004250A (es) | Derivados de imidazo[1,5-a]triazolo[1,5-d]benzodiazepina para el tratamiento de trastornos cognitivos. | |
| NZ519126A (en) | Novel IL-8 receptor antagonists | |
| MXPA02011464A (es) | Derivados 1,4-diazepan-2,5-diona y su uso como antagonistas del receptor de la nk-1. | |
| ATE337827T1 (de) | N-aryl-4,5-diaminopyrazole und diese verbindungen enthaltende färbemittel | |
| HUP0101311A1 (hu) | 3-Szubsztituált 3,4,5,7-tetrahidro-pirrolo[3',4':4,5]tieno[2,3-d]pirimidin-származékok, eljárás előállításukra és alkalmazásuk 5-HT antagonistákként | |
| HK1049486A1 (zh) | 作為mcp-1受體拮抗劑的吲類衍生物 | |
| AR021094A1 (es) | Compuestos heterociclicos inhibidores de la fosfodiesterasa iv y su uso para el tratamiento de enfermedades inflamatorias | |
| HU0103912D0 (en) | Use of substituted alkylpyridazinone derivatives for the preparation of pharmaceutical compositions with anxiolytic activity | |
| IS7152A (is) | Glýsín-setin þíeno[2,3-d]pýrimidín með sameinaða LH og FSH gerandefnisvirkni | |
| ATE238300T1 (de) | (3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl)-3-(1 - indol-3-yl)-alkylamine | |
| AU2003260569A1 (en) | Oxophenyl-cyclohexyl-propanolamine derivatives, production and use thereof in therapeutics | |
| NO308304B1 (no) | Nye 5H-thiazol[3,2-a]pyrimidin-5-on derivater, anvendelse derav for fremstilling av farmasøytiske sammensetninger, farmasøytiske sammensetninger inneholdende derivatene, samt et preparat til behandling av psykose, schizofreni og angst | |
| MY138045A (en) | New benzo[b]pyrano[3,2-h]acridin-7-one cinnamate compounds, a process for their preparation and pharmaceutical compositions containing them |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |