MXPA04001142A - Sintesis bidireccional de agentes de transporte de oligoguanidina. - Google Patents

Sintesis bidireccional de agentes de transporte de oligoguanidina.

Info

Publication number
MXPA04001142A
MXPA04001142A MXPA04001142A MXPA04001142A MXPA04001142A MX PA04001142 A MXPA04001142 A MX PA04001142A MX PA04001142 A MXPA04001142 A MX PA04001142A MX PA04001142 A MXPA04001142 A MX PA04001142A MX PA04001142 A MXPA04001142 A MX PA04001142A
Authority
MX
Mexico
Prior art keywords
oligoguanidine
compounds
transport agents
synthesis
directional synthesis
Prior art date
Application number
MXPA04001142A
Other languages
English (en)
Spanish (es)
Inventor
C Jessop Theodore
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Publication of MXPA04001142A publication Critical patent/MXPA04001142A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
MXPA04001142A 2001-08-03 2002-08-02 Sintesis bidireccional de agentes de transporte de oligoguanidina. MXPA04001142A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31030501P 2001-08-03 2001-08-03
PCT/US2002/024645 WO2003014076A2 (en) 2001-08-03 2002-08-02 Bi-directional synthesis of oligoguanidine transport agents

Publications (1)

Publication Number Publication Date
MXPA04001142A true MXPA04001142A (es) 2004-09-13

Family

ID=23201904

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04001142A MXPA04001142A (es) 2001-08-03 2002-08-02 Sintesis bidireccional de agentes de transporte de oligoguanidina.

Country Status (6)

Country Link
US (1) US7067698B2 (cg-RX-API-DMAC10.html)
EP (1) EP1419172A4 (cg-RX-API-DMAC10.html)
JP (1) JP2004537596A (cg-RX-API-DMAC10.html)
CA (1) CA2455951A1 (cg-RX-API-DMAC10.html)
MX (1) MXPA04001142A (cg-RX-API-DMAC10.html)
WO (1) WO2003014076A2 (cg-RX-API-DMAC10.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007038169A2 (en) * 2005-09-23 2007-04-05 Nitto Denko Corporation Multi-valent guanidinium compounds for molecular translocation across cellular membranes and epithelial tissues
WO2007038172A2 (en) * 2005-09-23 2007-04-05 Nitto Denko Corporation Guanidinium carriers
US7700565B2 (en) * 2005-09-23 2010-04-20 Nitto Denko Corporation Peptide nucleic acid based guanidinium compounds
US20100062465A1 (en) * 2006-04-21 2010-03-11 Ronen Sabrina M Detection of Histone Deacetylase Inhibition
US8624006B2 (en) 2007-04-09 2014-01-07 The Regents Of The University Of California One-pot synthesis of alpha/beta-O-glycolipids
PT3149025T (pt) 2014-05-21 2019-08-01 Entrada Therapeutics Inc Peptídeos penetrantes de células e métodos de fabrico e utilização dos mesmos
US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
WO2016033368A1 (en) 2014-08-27 2016-03-03 Ohio State Innovation Foundation Improved peptidyl calcineurin inhibitors
US11339192B2 (en) 2017-10-04 2022-05-24 Ohio State Innovation Foundation Bicyclic peptidyl inhibitors
EP3746105A4 (en) 2018-01-29 2022-05-18 Ohio State Innovation Foundation CYCLIC PEPTIDYLIN HIBITORS OF THE CAL-PDZ-BINDING DOMAIN
US11576946B2 (en) 2018-01-29 2023-02-14 Ohio State Innovation Foundation Peptidyl inhibitors of calcineurin-NFAT interaction
WO2019165183A1 (en) 2018-02-22 2019-08-29 Entrada Therapeutics, Inc. Compositions and methods for treating mitochondrial neurogastrointestinal encephalopathy
WO2019217682A1 (en) 2018-05-09 2019-11-14 Ohio State Innovation Foundation Cyclic cell-penetrating peptides with one or more hydrophobic residues
AU2021386370A1 (en) 2020-11-24 2023-06-22 Lyell Immunopharma, Inc. Methods for making, compositions comprising, and methods of using rejuvenated t cells

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4694086A (en) * 1983-10-05 1987-09-15 Toray Industries, Inc. Guanidine derivatives
EP0684958B1 (en) * 1993-02-17 1998-06-10 Btg International Limited Polymers containing guanidino groups for use in therapy
US5627194A (en) * 1993-11-17 1997-05-06 Allelix Biopharmaceuticals Inc. Anti-viral guanidino-substituted compounds
US5925552A (en) * 1996-04-25 1999-07-20 Medtronic, Inc. Method for attachment of biomolecules to medical devices surfaces
EP0941122B1 (en) * 1996-08-13 2003-10-29 Chiron Corporation Compositions for polynucleotide delivery
TW499412B (en) * 1996-11-26 2002-08-21 Dimensional Pharm Inc Aminoguanidines and alkoxyguanidines as protease inhibitors
WO1998036743A1 (en) * 1997-02-21 1998-08-27 Cypros Pharmaceutical Corporation Neuroprotective poly-guanidino compounds which block presynaptic n and p/q calcium channels
ES2210761T3 (es) * 1997-05-21 2004-07-01 The Board Of Trustees Of The Leland Stanford Junior University Composicion y procedimiento para mejorar el transporte a traves de las membranas biologicas.
US6072075A (en) * 1997-05-22 2000-06-06 The Regents Of The University Of California Guanidinylation reagents
US6623576B2 (en) * 1998-10-28 2003-09-23 Basf Aktiengesellschaft Continuous manufacture of superabsorbent/ion exchange sheet material
US6222091B1 (en) * 1997-11-19 2001-04-24 Basf Aktiengesellschaft Multicomponent superabsorbent gel particles
US6767904B2 (en) * 1998-03-06 2004-07-27 Bringham Young University Steroid derived antibiotics
US6350738B1 (en) * 1998-03-06 2002-02-26 Brigham Young University Steroid derived antibiotics
US6605115B1 (en) 1999-06-05 2003-08-12 Board Of Trustees Of The Leland Stanford Junior University Method and composition for inhibiting cardiovascular cell proliferation
WO2001013957A2 (en) 1999-08-24 2001-03-01 Cellgate, Inc. Enhancing drug delivery across and into epithelial tissues using oligo arginine moieties

Also Published As

Publication number Publication date
WO2003014076A2 (en) 2003-02-20
EP1419172A4 (en) 2007-10-03
EP1419172A2 (en) 2004-05-19
CA2455951A1 (en) 2003-02-20
JP2004537596A (ja) 2004-12-16
WO2003014076A3 (en) 2003-10-09
US7067698B2 (en) 2006-06-27
US20030073807A1 (en) 2003-04-17

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